BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//UM//UM*Events//EN
CALSCALE:GREGORIAN
BEGIN:VTIMEZONE
TZID:America/Detroit
TZURL:http://tzurl.org/zoneinfo/America/Detroit
X-LIC-LOCATION:America/Detroit
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20070311T020000
RRULE:FREQ=YEARLY;BYMONTH=3;BYDAY=2SU
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20071104T020000
RRULE:FREQ=YEARLY;BYMONTH=11;BYDAY=1SU
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTAMP:20171101T181542
DTSTART;TZID=America/Detroit:20171101T160000
DTEND;TZID=America/Detroit:20171101T173000
SUMMARY:Other:RNA structure heterogeneity
DESCRIPTION:RNA is unique among all biomolecules as it can be both information-storing and enzymatic. These features are tightly linked to its structure\, in which base-pairing interactions give rise to a highly folded macromolecule. Indeed\, in addition to the genetic code\, which specifies the composition of proteins\, we now know there is a secondary layer of information encoded in every transcript in the form of RNA structure that can regulate processes as diverse as splicing\, localization\, and translation efficiency. Our lab has developed approaches to probe RNA structure at single molecule and single nucleotide level\, which are capable of detecting alternative RNA structures forming from the same underlying sequence. Application of these approaches to Human Immunodeficiency Virus-1 (HIV-1) reveals HIV-1 genomic RNA structure heterogeneity with novel functional implications. \n                        \nSilvia Rouskin (MIT Whitehead Institute)
UID:45520-10200818@events.umich.edu
URL:https://events.umich.edu/event/45520
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Chemistry,Science
LOCATION:Chemistry Dow Lab - 1640
CONTACT:
END:VEVENT
END:VCALENDAR