{ "83879-21619426": { "datetime_modified":"20210511T124519", "datetime_start":"20210604T080000", "datetime_end":"20210604T230000", "has_end_time":1, "date_start":"2021-06-04", "date_end":"2021-06-04", "time_start":"08:00:00", "time_end":"23:00:00", "time_zone":"America\/Detroit", "event_title":"Become a UROP Research Mentor", "occurrence_title":"", "combined_title":"Become a UROP Research Mentor", "event_subtitle":"", "event_type":"Other", "event_type_id":"22", "description":"Submit a Research Project for the 2021-2022 Academic Year: https:\/\/lsa.umich.edu\/urop\/research-mentors.html\r\n\r\nUROP Research Mentors are faculty and post-doc researchers from across all U-M's 19 Schools and Colleges who provide undergraduate student researchers an opportunity to engage in research activities that help them learn about the pursuit of knowledge within an academic discipline. This early exposure to research fosters a valuable academic experience for students. 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Student research assistants work alongside a faculty member, research scientist or professional practitioner on an ongoing or new research project.\r\n\r\nLearn more and apply at: myumi.ch\/uropyearone\r\n\r\nApplications being accepted on a rolling basis.", "occurrence_notes":"Apply at: myumi.ch\/uropyearone", "guid":"83923-21617050@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/83923", "building_id":"1005046", "building_name":"Undergraduate Science Building", "campus_maps_id":"508", "room":"", "location_name":"Undergraduate Science Building", "has_livestream":0, "cost":"", "tags":["AEM Featured","Applications","first-generation","Free","Interdisciplinary","Networking","Research","Undergraduate","Undergraduate Students","Urop"], "website":"http:\/\/myumi.ch\/uropyearone", "sponsors":[ { "group_name":"UROP - Undergraduate Research Opportunity Program", "group_id":"3702", "website":"https:\/\/twitter.com\/UROPumich" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2021\/04\/event_83923_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2021\/04\/event_83923_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2021\/04\/event_83923_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2021\/04\/event_83923_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2021\/04\/event_83923_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2021\/04\/event_83923_original-1.png" }, "occurrence_count":181, "first_occurrence":21617016 } , "82067-21014949": { "datetime_modified":"20210804T182828", "datetime_start":"20210604T080000", "datetime_end":"20210604T230000", "has_end_time":1, "date_start":"2021-06-04", "date_end":"2021-06-04", "time_start":"08:00:00", "time_end":"23:00:00", "time_zone":"America\/Detroit", "event_title":"UROP Research Scholars Application now open", "occurrence_title":"", "combined_title":"UROP Research Scholars Application now open", "event_subtitle":"", "event_type":"Careers \/ Jobs", "event_type_id":"2", "description":"The UROP Research Scholars Program is designed for students who want to expand on their first year UROP experience and participate in UROP for a second year at an advanced level. 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The exhi\u00adbi\u00adtion blends archival mate\u00adri\u00adals, social and polit\u00adi\u00adcal arti\u00adfacts, pho\u00adtog\u00adra\u00adphy, and art to explore the con\u00adgru\u00adent and con\u00adtra\u00addict\u00ading ideas, aes\u00adthet\u00adics, and cul\u00adtures work\u00ading to make the halal metrop\u00ado\u00adlis both a real and imag\u00adi\u00adnary entity.\r\n\r\nFea\u00adtur\u00ading works by:\r\n\r\nAmna Asghar\r\nQais Assali\r\nBGIRL MAMA\r\nNour Ball\u00adout\r\nAdnan Charara\r\nKecia Escoe\r\nParisa Ghaderi\r\nAnthony Keith Giannini\r\nRazi Jafri\r\nOsman Khan\r\nMaamoul Press\r\nEndi Poskovic\r\nHaleem \u200b\u2018Stringz\u2019 Rasul\r\nReem Taki\r\n\r\nThis exhi\u00adbi\u00adtion is pre\u00adsented in part\u00adner\u00adship with the Uni\u00adver\u00adsity of Michigan-Dearborn\u2019s Cen\u00adter for Arab Amer\u00adi\u00adcan Stud\u00adies (CAAS), with sup\u00adport from the Knight Foun\u00adda\u00adtion, the Doris Duke Foun\u00adda\u00adtion, the Andy Warhol Foun\u00adda\u00adtion for the Visual Arts, the El-Hibri Foun\u00adda\u00adtion, the Com\u00admu\u00adnity Foun\u00adda\u00adtion of SE Michi\u00adgan, and the Michi\u00adgan Human\u00adi\u00adties Council.", "occurrence_notes":null, "guid":"84359-21623506@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/84359", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Stamps Gallery, 201 South Division Street Ann Arbor, Michigan 48104", "has_livestream":0, "cost":"", "tags":["Art","Detroit","Exhibition","Multidisciplinary Design","Muslim"], "website":"https:\/\/stamps.umich.edu\/events\/halal-metropolis", "sponsors":[ { "group_name":"Penny W Stamps School of Art & Design", "group_id":"3157", "website":"http:\/\/stamps.umich.edu\/" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2021\/06\/event_84359_original-1.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2021\/06\/event_84359_original-1.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2021\/06\/event_84359_original-1.jpeg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2021\/06\/event_84359_original-1.jpeg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2021\/06\/event_84359_original-1.jpeg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2021\/06\/event_84359_original-1.jpeg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2021\/06\/event_84359_original-1.jpeg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2021\/06\/event_84359_original-1.jpeg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2021\/06\/event_84359_original-1.jpeg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2021\/06\/event_84359_original-1.jpeg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2021\/06\/event_84359_original-1.jpeg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2021\/06\/event_84359_original-1.jpeg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2021\/06\/event_84359_original-1.jpeg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2021\/06\/event_84359_original-1.jpeg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2021\/06\/event_84359_original-1.jpeg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2021\/06\/event_84359_original-1.jpeg" }, "occurrence_count":26, "first_occurrence":21623505 } , "84067-21619803": { "datetime_modified":"20210518T091930", "datetime_start":"20210604T110000", "datetime_end":"20210604T123000", "has_end_time":1, "date_start":"2021-06-04", "date_end":"2021-06-04", "time_start":"11:00:00", "time_end":"12:30:00", "time_zone":"America\/Detroit", "event_title":"Southeast Asian Languages and Scholarship Information Session", "occurrence_title":"", "combined_title":"Southeast Asian Languages and Scholarship Information Session", "event_subtitle":"", "event_type":"Livestream \/ Virtual", "event_type_id":"24", "description":"Want to learn about all the Southeast Asian languages we offer? Want to learn about opportunities to work in Southeast Asia and scholarships for these languages? Attend this information session! You will listen to our Filipino, Indonesia, Thai, and Vietnamese instructors and students directly. Our center staff will also answer questions about applying for a first year language scholarship and FLAS fellowship. Graduate and undergraduates at all levels and with varying backgrounds are welcome to attend. There will be a virtual showcase of Southeast Asian unique cultures as well as games and door prizes (T-shirts, tote bags and notebooks, and Amazon gift cards). 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But re-examining these assumptions can often reveal something new. In this talk, Richard Redding discusses how, in re-examining his own assumptions, he uncovered new insights into the diet of laborers at Giza in ancient Egypt.\r\n\r\nKelsey Museum Flash Talks are 15-minute Zoom lectures by Kelsey curators, staff members, researchers, and graduate students talking about their recent research or current projects. Each presentation is followed by 15 minutes of Q&A. Flash Talks are free and open to all visitors. 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Wang", "occurrence_title":"", "combined_title":"PhD Defense: William Y. Wang: Biomimetic Microsystems to Study Cell Migration Mechanoreciprocity in Health and Disease", "event_subtitle":"Biomimetic Microsystems to Study Cell Migration Mechanoreciprocity in Health and Disease", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"Mechanoreciprocity in cell migration is an emerging concept describing the dynamic, bi-directional interactions between migrating cells and the surrounding extracellular matrix (ECM) they negotiate. Migrating cells not only sense and adapt to biochemical and biophysical ECM cues, but also, exert forces, deposit matrix, and secrete chemokines, matrix metalloproteinases, and matrix crosslinking enzymes that dynamically alter the same ECM properties known to regulate cell migration. Due to limitations in standard cell migration assays, how matrix properties influence cell migration and in turn, how cells influence matrix properties, has previously been studied as separate processes. However, observations from development, wound healing, and a variety of disease processes highlight the interdependency and iterative relationship between cell migration and ECM. An improved understanding of the underlying mechanisms that orchestrate the coevolution of migrating cells and ECM will aid in tissue engineering and regenerative medicine efforts to guide repair fibroblasts to regenerate wound beds, direct collective endothelial cell migration to vascularize ischemic or engineered tissue grafts and confine otherwise metastatic cancer cells to the primary tumor. Thus, the focus of this dissertation is to design biomimetic microsystems that afford investigation of cell migration mechanoreciprocity with a focus on fibroblasts, endothelial cells, and cancer cells.\r\n\r\n \r\n\r\nFirst, this thesis investigated how single mesenchymal cells (fibroblasts and cancer cells) migrate in fibrous stromal tissue settings, such as in trans-stromal cancer cell migration during metastasis. To model fibrous stromal tissue, 3D fiber networks were electrospun over microfabricated wells to define ECM mechanics. Independently tuning alignment and stiffness of these matrices resulted in two phenotypically distinct cell migration modes. In contrast to stiff matrices where cells migrated continuously in a traditional mesenchymal fashion, cells in deformable matrices stretched matrix fibers to store elastic energy; subsequent adhesion failure triggered sudden matrix recoil and rapid cell translocation (termed slingshot migration). Across a variety of cell types, traction force measurements revealed a relationship between cell contractility and the matrix stiffness where slingshot migration mode occurred optimally.\r\n\r\n \r\n\r\nNext, this thesis describes how microenvironmental cues influence collective endothelial cell migration during sprouting angiogenesis towards the design of pro-angiogenic biomaterials. This work employed a multiplexed angiogenesis-on-a-chip platform to assess the chemokine-directed 3D invasion of endothelial cells from a lumenized parent vessel into user-defined ECM. By tuning soluble and physical cues of the ECM, this work identified how 1) functional angiogenesis requires microenvironmental cues that balance cell invasion speed and proliferation; 2) dynamic interactions between sprout stalk cells and ECM regulates neovessel lumenization; and 3) imbuing microporosity within synthetic hydrogels can enhance endothelial cell invasion and angiogenic sprout lumenization.\r\n\r\n \r\n\r\nLastly, this thesis investigated how fibrous matrix cues activate quiescent vessel-lining endothelial cells into invasive tip cells in the context of fibrosis. Composite hydrogels (electrospun fiber segments suspended within 3D ECM) were integrated with the angiogenesis-on-a-chip platform. These studies establish that heightened matrix fiber density destabilizes cell-cell adherens junctions, reduces endothelium barrier function, and promotes the invasion of endothelial tip cells. Performing transcriptomic and secretomic analyses on fiber-induced tip endothelial cells revealed that fibrous ECM cues promote a fibrosis propagating phenotype.\r\n\r\n \r\n\r\nOverall, the work presented in this dissertation integrates tunable biomaterials with microfabricated devices to investigate cell migration mechanoreciprocity of single mesenchymal cell migration, the collective migration of endothelial cells during angiogenesis, and endothelial-mesenchymal transition of quiescent endothelial cells into a fibrosis propagating cell phenotype.\r\n\r\n \r\n\r\nDate: Friday, June 4, 2021\r\n\r\nTime: 12:30 PM\r\n\r\nZoom: https:\/\/umich.zoom.us\/meeting\/register\/tJcsf-uhpj4vGtyM7x-td2VV39BzqmF_zoob (Zoom link requires prior registration)\r\n\r\nChair: Dr. Brendon Baker", "occurrence_notes":"(Zoom link requires prior registration)", "guid":"84102-21620248@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/84102", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Virtual (Zoom)", "has_livestream":1, "livestream_type":"other", "livetream_require_login":0, "livestream_id":"", "livestream_link":"https:\/\/umich.zoom.us\/meeting\/register\/tJcsf-uhpj4vGtyM7x-td2VV39BzqmF_zoob", "cost":"", "tags":["Basic Science","Biointerfaces","Biology","biomedical","biomedical engineering","Bioninterfaces","Biosciences","Biotechnology","bme","engineer","engineering","Life Science","Science"], "website":"http:\/\/twitter.com\/umbme", "sponsors":[ { "group_name":"Biomedical Engineering", "group_id":"1143", "website":"https:\/\/www.facebook.com\/profile.php?id=100094127215673" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2021\/05\/event_84102_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2021\/05\/event_84102_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2021\/05\/event_84102_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2021\/05\/event_84102_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2021\/05\/event_84102_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2021\/05\/event_84102_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2021\/05\/event_84102_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2021\/05\/event_84102_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2021\/05\/event_84102_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2021\/05\/event_84102_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2021\/05\/event_84102_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2021\/05\/event_84102_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2021\/05\/event_84102_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2021\/05\/event_84102_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2021\/05\/event_84102_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2021\/05\/event_84102_original-1.png" }, "occurrence_count":1, "first_occurrence":21620248 } , "84131-21620332": { "datetime_modified":"20210601T112542", "datetime_start":"20210604T130000", "datetime_end":"20210604T140000", "has_end_time":1, "date_start":"2021-06-04", "date_end":"2021-06-04", "time_start":"13:00:00", "time_end":"14:00:00", "time_zone":"America\/Detroit", "event_title":"Crucial Conversations for Societal Change: Reflection, Research & Resolve", "occurrence_title":"", "combined_title":"Crucial Conversations for Societal Change: Reflection, Research & Resolve", "event_subtitle":"", "event_type":"Livestream \/ Virtual", "event_type_id":"24", "description":"U-M leadership, faculty, graduate and undergraduate students will gather on June 4 to explore and reflect on the progress that has been made and the many problems that still plague the world today related to racism, violence, and inequality, since the original Conversation for Societal Change dialogue nearly one year ago. \r\n\r\nModerated by Katrina Wade-Golden, deputy chief diversity officer, panelists President Mark Schlissel; Eddie Washington, Jr., Executive Director of the Division of Public Safety and Security; Earl Lewis, University Professor of History, Afroamerican and African Studies and Public Policy, director of the Center for Social Solutions, and co-chair of the Advancing Public Safety at the University of Michigan Task Force; and Rebecca Cunningham, Vice President for Research will also be joined by representatives from the U-M graduate and undergraduate communities. \r\n\r\nJoin this constructive and crucial conversation about race, law enforcement, protest and reform at 1pm on June 4 via Zoom or YouTube.", "occurrence_notes":null, "guid":"84131-21620332@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/84131", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Virtual", "has_livestream":1, "livestream_type":"other", "livetream_require_login":0, "livestream_id":"", "livestream_link":"myumi.ch\/jxyZ3", "cost":"", "tags":["Activism","Discussion","Diversity","Diversity Equity and Inclusion","Social Impact","Social Inequities","Social Justice"], "website":"http:\/\/myumi.ch\/jxyZ3", "sponsors":[ { "group_name":"Public Engagement & Impact", "group_id":"4640", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2021\/06\/event_84131_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2021\/06\/event_84131_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2021\/06\/event_84131_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2021\/06\/event_84131_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2021\/06\/event_84131_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2021\/06\/event_84131_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2021\/06\/event_84131_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2021\/06\/event_84131_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2021\/06\/event_84131_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2021\/06\/event_84131_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2021\/06\/event_84131_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2021\/06\/event_84131_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2021\/06\/event_84131_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2021\/06\/event_84131_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2021\/06\/event_84131_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2021\/06\/event_84131_original-1.png" }, "occurrence_count":1, "first_occurrence":21620332 } , "84066-21619787": { "datetime_modified":"20210518T161413", "datetime_start":"20210604T140000", "datetime_end":"20210604T153000", "has_end_time":1, "date_start":"2021-06-04", "date_end":"2021-06-04", "time_start":"14:00:00", "time_end":"15:30:00", "time_zone":"America\/Detroit", "event_title":"A Celebration of Black Music II", "occurrence_title":"", "combined_title":"A Celebration of Black Music II: I Know why the Caged Bird Sings", "event_subtitle":"I Know why the Caged Bird Sings", "event_type":"Performance", "event_type_id":"15", "description":"\u00bbI know why the caged bird sings\u00ab \u2013 it sings of freedom in order not to lose hope. 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