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        "event_title":"UROP Research Scholars Application now open",
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        "event_title":"A Garden of Earthy Delights: Ceramic Sculptures by Ann Arbor Potters Guild at Matthaei Botanical Gardens",
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        "event_title":"BME Ph.D. Defense: Yuan Li",
        "occurrence_title":"",
        "combined_title":"BME Ph.D. Defense: Yuan Li: Investigation of High Order Diffusion Models in Glioblastoma by  Exploring High b-value, Echo time (TE), and Diffusion Time",
        "event_subtitle":"Investigation of High Order Diffusion Models in Glioblastoma by  Exploring High b-value, Echo time (TE), and Diffusion Time",
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        "description":"Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults and has a poor prognosis with a median survival of approximately 14 months. Clinical standard assessment of therapy response and tumor progression is based upon post-contrast T1-weighted (T1W) and fluid-attenuated inversion recovery (FLAIR) T2-weighted (T2W) magnetic resonance images (MRI).\u00a0 However, contrast enhancement observed on the post-contrast T1W MRI is affected not only by tumor growth but also effects of radiation, anti-angiogenesis drugs and chemotherapy, due to the fact that it represents blood-brain barrier disruption. Another problem is that abnormality on T2W FLAIR images is influenced by T2 changes of tumor cells as well as edema and necrosis that always co-exist within GBM. Diffusion weighted (DW) imaging has been proposed to overcome these limitations. Conventional DW images quantify apparent diffusion coefficient (ADC) with b-values between 0 and 1000 s\/mm2\u00a0using a mono-exponential decay. One limitation is that co-existence of edema in clinical GBM elevates ADC.\r\n\u00a0\r\nIn diffusion MRI, there are three dimensions of parameter spaces that we could explore in research \u2014b value, diffusion time (t) and echo time (TE). Hence, we investigated and developed high order diffusion models in these three spaces and evaluated whether they could reveal more features of GBM.\r\n\u00a0\r\nIn the b-value space, we investigated a microstructure model (MSM), in which modulation of diffusion gradient with cell size is considered, with high b-value diffusion images in the patients with GBM pre-radiation therapy (RT). We found apparent cell size (ARS), extracellular diffusion coefficient (Dex) and intracellular fractional volume (Vin) in tumor were significantly greater than ones in normal tissue and edema. In addition, we investigated diffusion kurtosis imaging (DKI) in GBM pre-RT and mid-RT, and found pre-RT mean kurtosis of the tumor could provide a predictive value of overall survival (OS) additional to clinical prognostic factors.\r\n\u00a0\r\nIn the TE space,\u00a0T2-Relaxation-Diffusion correlation experiments can be powerful in resolving water compartments with respect to their size and chemical composition, but the problem is ill-posed.\u00a0We\u00a0simplified the T2-Relaxation-Diffusion correlation to consider the T2 values and diffusion coefficients in a 2x2 fashion. We found that\u00a0there were significant differences between fast and slow diffusion coefficients and between associated T2 values in tumor, cortex, deep GM, and edema. Multivariate Cox model showed the fractional volume of slow component (Vs) mid-RT may add a predictive value to clinical factors.\r\n\u00a0\r\nIn diffusion time space, we applied three different diffusion times using pulsed diffusion gradients (PG) and oscillating gradients at frequencies of 30 Hz (OS30) and 50 Hz (OS50) using a prototype sequence. Using a random walk with barriers model, we estimated cell diameter, unrestricted diffusion coefficient (D0) at a short time limit, bulk diffusion coefficient (Dinf) at a long time limit, cell membrane permeability and effective restriction in the contrast-enhanced tumor. Those parameters provide microstructural information in the GBM and need to be further investigated and validated with pathology.\r\n\u00a0\r\nPrevious studies have mainly investigated high order diffusion models in prostate cancer and xenograft tumor models, and only a few studies investigated GBM. The current knowledge about the relationship between model parameters and physiological\/pathological features in GBM are still limited. Our research in GBM could lead to better imaging means for GBM diagnosis, tumor target definition for radiation therapy, and therapy response assessment.\r\n\u00a0\r\nDate:\u00a0Thursday, July 22, 2021\r\nTime:\u00a02:00 PM\r\nZoom:\u00a0https:\/\/umich.zoom.us\/j\/96213084276\r\n\r\nChair:\u00a0Dr. Yue Cao",
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        "event_title":"CoderSpaces (Thursdays)",
        "occurrence_title":"",
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        "website":"https:\/\/datascience.isr.umich.edu\/events\/coderspaces\/",
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        "date_end":"2021-07-22",
        "time_start":"14:00:00",
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        "time_zone":"America\/Detroit",
        "event_title":"Coffee Chats for Graduate Students: Cover Letters",
        "occurrence_title":"",
        "combined_title":"Coffee Chats for Graduate Students: Cover Letters",
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        "event_type":"Livestream \/ Virtual",
        "event_type_id":"24",
        "description":"We are offering a series of virtual coffee chats for the Rackham community, hosted by Rackham\u2019s embedded University Career Center career counselor. The general topic for this session is writing effective cover letters, including strategies for tailoring your cover letters to each job application. There will be time for Q&A. This event is intended to be interactive and therefore a recording will not be available.\nRegistration is required at https:\/\/myumi.ch\/jxXd9.\nWe want to ensure full and equitable participation in our events. If an accommodation would promote your full participation in this event, please follow the registration link to indicate your accommodation requirements. Please let us know as soon as possible in order to have adequate time, preferably one week, to arrange for your requested accommodations or an effective alternative.",
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        "event_title":"HACU Corporate Internship Program Webinar - JLL",
        "occurrence_title":"",
        "combined_title":"HACU Corporate Internship Program Webinar - JLL",
        "event_subtitle":"",
        "event_type":"Careers \/ Jobs",
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        "description":"HACU, is co-hosting a webinar with one of our newest corporate partners, JLL, as part of HACU\u2019s National Internship Program (Corporate Component) to promote available internships and entry-level opportunities with JLL.\n\nThe webinar is scheduled to take place on Thursday, July22nd, from 1:00 PM \u2013 2:00 PM CDT\/2:00 PM \u2013 3:00 PM EDT\/11:00 AM \u2013 12:00 PM PDT. We are looking for undergraduate students from the followingmajors to attend: \n\n\u2022\tEngineering\n\u2022\tFacilities Management\n\u2022\tReal Estate\n\u2022\tBusiness\n\u2022\tAccounting\n\u2022\tFinance\n\u2022\tSales\n\u2022\tMarketing\n\u2022\tEconomics\n\u2022\tAny related majors\n",
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        "datetime_modified":"20210712T173128",
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        "event_title":"How to Use TransPop Data: The first national probability sample of transgender individuals in the United States",
        "occurrence_title":"",
        "combined_title":"How to Use TransPop Data: The first national probability sample of transgender individuals in the United States",
        "event_subtitle":"",
        "event_type":"Presentation",
        "event_type_id":"16",
        "description":"Join us for a virtual presentation of TransPop, the first national probability sample of transgender individuals in the United States. During this presentation you'll learn how to use these data to reach your own groundbreaking results.\r\n\r\nThe TransPop study not only describes the demographic make-up of the transgender population and their experiences related to identity and transition, but also aims to provide information on areas like health outcomes, health care access, quality of life, and experiences with discrimination.\r\n\r\nIn addition to being the first national probability sample of transgender individuals in the United States, it also includes a comparative cisgender sample. A primary goal of this study was to provide researchers with a representative sample of transgender people in the United States. The study examines a variety of health-relevant domains including health outcomes and health behaviors, experiences with interpersonal and institutional discrimination, identity, transition-related experiences, and basic demographic characteristics (age, race\/ethnicity, religion, political party affiliation, marital status, employment, income, location, sex, gender, and education).\r\n\r\nThe TransPop study is available at https:\/\/doi.org\/10.3886\/ICPSR37938.v1.\r\n\r\nThis webinar is free and open to the public. A live transcript will be available. The webinar will be recorded, and the recording and slides will be sent to all registrants after the webinar.\r\n\r\nZoom FAQs for Attendees: http:\/\/myumi.ch\/kx2oo",
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                "guid":"84448-21623998@events.umich.edu",
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        "tags":["Activism","Data","Data Curation","Data Science","Diversity Equity and Inclusion","Free","Lecture","Social Sciences","Talk","Virtual","Webcast","Webinar"],
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                "group_id":"3196",
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