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If you would like to volunteer, please start the enrollment process by creating an account on the Children Center's\u00a0Volunteer Site found HERE.\u00a0After your account is created, the Children's Center will reach out to you within 2 business days to answer any questions and discuss the next steps.In accordance with the CMS Vaccine Mandate, those volunteering in-person at the Children\u2019s Center are required to be fully vaccinated and must provide proof of full vaccination upon request.", "occurrence_notes":null, "guid":"93885-21787814@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/93885", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"The Children's Center ", "has_livestream":0, "cost":"", "tags":[], "website":"https:\/\/maizepages.umich.edu\/event\/8007835", "sponsors":[ { "group_name":"Maize Pages Student Organizations", "group_id":"2390", "website":"" } ], 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Students learn valuable academic skills, applying these skills to their research project, academics, and future career opportunities, while receiving academic credit or compensation for their efforts in research work.\r\n\r\nApplications are accepted on a rolling basis.\r\nLearn more about Changing Gears at: myumi.ch\/uropcg", "occurrence_notes":"Apply at myumi.ch\/uropcg", "guid":"92406-21690938@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/92406", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Off Campus Location", "has_livestream":0, "cost":"", "tags":["AEM Featured","Applications","first-generation","Free","Interdisciplinary","Networking","Research","research data","Social Impact","The College Of Literature, Science, And The Arts","Transfer Students","Undergraduate","Undergraduate Students","Urop"], "website":"https:\/\/lsa.umich.edu\/urop\/Prospective-Students\/fall-winter-programs\/changing-gears-program.html", "sponsors":[ { "group_name":"UROP - Undergraduate Research Opportunity Program", "group_id":"3702", "website":"https:\/\/twitter.com\/UROPumich" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2022\/02\/event_92406_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2022\/02\/event_92406_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2022\/02\/event_92406_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2022\/02\/event_92406_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2022\/02\/event_92406_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2022\/02\/event_92406_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2022\/02\/event_92406_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2022\/02\/event_92406_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2022\/02\/event_92406_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2022\/02\/event_92406_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2022\/02\/event_92406_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2022\/02\/event_92406_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2022\/02\/event_92406_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2022\/02\/event_92406_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2022\/02\/event_92406_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2022\/02\/event_92406_original-1.png" }, "occurrence_count":181, "first_occurrence":21690856 } , "94707-21761621": { "datetime_modified":"20220419T113622", "datetime_start":"20220509T080000", "datetime_end":"20220509T190000", "has_end_time":1, "date_start":"2022-05-09", "date_end":"2022-05-09", "time_start":"08:00:00", "time_end":"19:00:00", "time_zone":"America\/Detroit", "event_title":"Mail Art: Postcards from the Pandemic", "occurrence_title":"", "combined_title":"Mail Art: Postcards from the Pandemic", "event_subtitle":"", "event_type":"Exhibition", "event_type_id":"7", "description":"View postcards from the pandemic. When the U-M Library and the Ann Arbor District Library asked community members to submit handmade postcards \u2014 mail art \u2014 in 2020 to capture the emotions and experiences of the Ann Arbor and U-M community during challenging pandemic times, creative pieces of art started arriving at the library. 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Student research assistants work alongside a faculty member, research scientist or professional practitioner on an ongoing or new research project.\r\n\r\nLearn more and apply at: myumi.ch\/uropyearone\r\n\r\nApplications being accepted on a rolling basis.", "occurrence_notes":null, "guid":"83923-21785163@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/83923", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":null, "has_livestream":0, "cost":"", "tags":["AEM Featured","Applications","first-generation","Free","Interdisciplinary","Networking","Research","Undergraduate","Undergraduate Students","Urop"], "website":"http:\/\/myumi.ch\/uropyearone", "sponsors":[ { "group_name":"UROP - Undergraduate Research Opportunity Program", "group_id":"3702", "website":"https:\/\/twitter.com\/UROPumich" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2021\/04\/event_83923_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2021\/04\/event_83923_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2021\/04\/event_83923_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2021\/04\/event_83923_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2021\/04\/event_83923_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2021\/04\/event_83923_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2021\/04\/event_83923_original-1.png" }, "occurrence_count":181, "first_occurrence":21617016 } , "91080-21676522": { "datetime_modified":"20220117T095807", "datetime_start":"20220509T080000", "datetime_end":"20220509T230000", "has_end_time":1, "date_start":"2022-05-09", "date_end":"2022-05-09", "time_start":"08:00:00", "time_end":"23:00:00", "time_zone":"America\/Detroit", "event_title":"UROP Research Scholars Program Application Open", "occurrence_title":"", "combined_title":"UROP Research Scholars Program Application Open: Continue your UROP research experience", "event_subtitle":"Continue your UROP research experience", "event_type":"Careers \/ Jobs", "event_type_id":"2", "description":"The UROP Research Scholars Program is designed for students who want to expand on their first year UROP experience and participate in UROP for a second year at an advanced level. 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Students are expected to explore various written and oral possibilities for communicating their research process, identifying the limits set by the discipline and the opportunities that lie beyond.\r\n\r\nApplications for the 2022-2023 academic year cohort open February 14th.\r\nPriority Deadline for the applications is March 18th\r\n\r\nLearn more at: myumi.ch\/uroprs", "occurrence_notes":"Apply at: myumi.ch\/uroprs", "guid":"91080-21676522@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/91080", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Off Campus Location", "has_livestream":0, "cost":"", "tags":["AEM Featured","Applications","Fellowship","first-generation","Interdisciplinary","Networking","Research","research data","Sophomore","The College Of Literature, Science, And The Arts","Undergraduate","Undergraduate Students","Urop"], "website":"http:\/\/myumi.ch\/uroprs", "sponsors":[ { "group_name":"UROP - 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All methods presented here build on a recently-proposed non-parametric approach to quantile regression that is analogous to local linear regression in the least-squares setting. A major challenge is that the raw local quantile estimates are cumbersome to interpret and gain insight from directly. Aiming to overcome this challenge, there are four main contributions herein. First, we demonstrate how a low-rank additive regression analysis can produce insight into a collection of local nonparametric quantile estimates. The low rank structure regularizes the noisy quantile estimates and facilitates interpretation of the findings. Second, we show how a multivariate dimension reduction approach provides a different type of insight into a collection of estimated conditional quantile functions. The third contribution of the thesis leverages the combination of nonparametric quantile estimation and low-rank regression in the context of mediation analysis. We show that this produces a novel quantile-based approach to mediation analysis that expresses direct and indirect effects in a concise and interpretable way. The final methodological contribution of the thesis is a framework for moment-based estimation of conditional covariance functions for stochastic processes. Throughout the thesis, we motivate our work through analyses looking at the proximal and distal factors predicting human blood pressure.", "occurrence_notes":null, "guid":"94978-21788179@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/94978", "building_id":"1000167", "building_name":"West Hall", "campus_maps_id":"163", "room":"438", "location_name":"West Hall", "has_livestream":0, "cost":"", "tags":["Dissertation"], "website":"", "sponsors":[ { "group_name":"Department of Statistics Dissertation Defenses", "group_id":"4045", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2022\/05\/event_94978_original-1.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_thumb\/media\/attachments\/2022\/05\/event_94978_original-1.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2022\/05\/event_94978_original-1.jpeg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2022\/05\/event_94978_original-1.jpeg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2022\/05\/event_94978_original-1.jpeg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2022\/05\/event_94978_original-1.jpeg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2022\/05\/event_94978_original-1.jpeg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2022\/05\/event_94978_original-1.jpeg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large_lightbox\/media\/attachments\/2022\/05\/event_94978_original-1.jpeg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2022\/05\/event_94978_original-1.jpeg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2022\/05\/event_94978_original-1.jpeg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2022\/05\/event_94978_original-1.jpeg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2022\/05\/event_94978_original-1.jpeg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2022\/05\/event_94978_original-1.jpeg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_large\/media\/attachments\/2022\/05\/event_94978_original-1.jpeg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_thumb\/media\/attachments\/2022\/05\/event_94978_original-1.jpeg" }, "occurrence_count":1, "first_occurrence":21788179 } , "92000-21684906": { "datetime_modified":"20220204T165932", "datetime_start":"20220509T090000", "datetime_end":"20220509T180000", "has_end_time":1, "date_start":"2022-05-09", "date_end":"2022-05-09", "time_start":"09:00:00", "time_end":"18:00:00", "time_zone":"America\/Detroit", "event_title":"Greek Manuscripts at the University of Michigan Library: A Celebration", "occurrence_title":"", "combined_title":"Greek Manuscripts at the University of Michigan Library: A Celebration", "event_subtitle":"", "event_type":"Exhibition", "event_type_id":"7", "description":"Splendors of the religious and artistic endeavors of Byzantine manuscript makers are on display in this exhibit of highlights from the Greek manuscript collection at the University of Michigan Library Special Collections Research Center.\u00a0The collection \u2014 110 codices (bound manuscripts) and fragments written in Greek from the fourth to the nineteenth centuries C.E. \u2014 is the largest such collection in the Western Hemisphere and provides unique insights into this era of achievement in textual transmission, calligraphy, illumination, and bookbinding.\u00a0The exhibit will be open during Audubon Room hours.\r\n\r\nA digital version of the exhibit will be available in the Audubon Room and online, and allows visitors to explore other pages of the manuscripts on display and other manuscripts from the collection.\r\n\r\nThis exhibit celebrates two recent publications based on the collection:\u00a0\r\n\r\n* Catalogue of Greek Manuscripts at the University of Michigan, Ann Arbor. Vol. 1., by Nadezhda Kavrus-Hoffmann (Ann Arbor: University of Michigan Press, 2021)\r\n\r\n* Tradition and Individuality: Bindings from the University of Michigan Greek Manuscript Collection, by Julia Miller (Ann Arbor: The Legacy Press, 2021)", "occurrence_notes":"Please check hours at lib.umich.edu", "guid":"92000-21684906@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/92000", "building_id":"1000181", "building_name":"Hatcher Graduate Library", "campus_maps_id":"65", "room":"Audubon Room, 1st floor", "location_name":"Hatcher Graduate Library", "has_livestream":0, "cost":"", "tags":["Classical Studies","Exhibition","Library"], "website":"", "sponsors":[ { "group_name":"University Library", "group_id":"1186", "website":"https:\/\/www.facebook.com\/UMichLibrary\/" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2022\/02\/event_92000_original-1.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2022\/02\/event_92000_original-1.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2022\/02\/event_92000_original-1.jpeg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2022\/02\/event_92000_original-1.jpeg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2022\/02\/event_92000_original-1.jpeg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2022\/02\/event_92000_original-1.jpeg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2022\/02\/event_92000_original-1.jpeg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2022\/02\/event_92000_original-1.jpeg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2022\/02\/event_92000_original-1.jpeg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2022\/02\/event_92000_original-1.jpeg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2022\/02\/event_92000_original-1.jpeg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2022\/02\/event_92000_original-1.jpeg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2022\/02\/event_92000_original-1.jpeg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2022\/02\/event_92000_original-1.jpeg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2022\/02\/event_92000_original-1.jpeg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2022\/02\/event_92000_original-1.jpeg" }, "occurrence_count":95, "first_occurrence":21684862 } , "94871-21778936": { "datetime_modified":"20220524T063051", "datetime_start":"20220509T093000", "datetime_end":"20220509T103000", "has_end_time":1, "date_start":"2022-05-09", "date_end":"2022-05-09", "time_start":"09:30:00", "time_end":"10:30:00", "time_zone":"America\/Detroit", "event_title":"Coffee with the CNO - Lorain and Youngstown Markets", "occurrence_title":"", "combined_title":"Coffee with the CNO - Lorain and Youngstown Markets", "event_subtitle":"", "event_type":"Careers \/ Jobs", "event_type_id":"2", "description":"Mercy Health is inviting students interested in a career with the Ministry to have virtual coffee with the Chief Nursing Officer, Stacie Call!\n \nPre-registered students will receive a virtual Starbucks gift card the day before the event so they can grab coffee and log-on for a great discussion with Stacie about the Youngstown and Lorain hospitals, job opportunities, education benefits, and all things Mercy Health! Representatives from University Relations and Talent Acquisition will also be available to answer questions. \n \nCoffee with the CNO will be on May 9, 2022 from 9:30am-10:30am in celebration of National Student Nurse Day on May 8. The event will begin promptly at 9:30am, so your coffee doesn't get cold!", "occurrence_notes":null, "guid":"94871-21778936@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/94871", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"", "has_livestream":0, "cost":"", "tags":[], "website":"", "sponsors":[ { "group_name":"University Career Center UCC", "group_id":"1140", "website":"http:\/\/careercenter.umich.edu" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21778936 } , "94501-21742778": { "datetime_modified":"20220524T063043", "datetime_start":"20220509T100000", "datetime_end":"20220509T110000", "has_end_time":1, "date_start":"2022-05-09", "date_end":"2022-05-09", "time_start":"10:00:00", "time_end":"11:00:00", "time_zone":"America\/Detroit", "event_title":"Discovering Your Passion: A Conversation with Roger Harris", "occurrence_title":"", "combined_title":"Discovering Your Passion: A Conversation with Roger Harris", "event_subtitle":"", "event_type":"Careers \/ Jobs", "event_type_id":"2", "description":"Your success is a train ride away.\n\nAmtrak connects businesses and communities across the country and we move America's workforce toward the future. We employ more than 20,000 diverse, energetic professionals in a variety of career fields throughout the United States. The safety of our passengers, our employees, the public and our operating environment is our priority and the success of our railroad is the result of our employees.\n\nMoving America Where it wants to go. We are not just a railroad; we are a company that moves people. With 21,000 route miles in 46 states, the District of Columbia and three Canadian provinces, Amtrak operates more than 300 trains each day \u2013 at speeds up to 150 mph \u2013 to more than 500 destinations. We move customers where they want to go by responding to their wants and needs. And by doing so, we connect communities, economies and families that make our nation great. We employ more than 20,000 diverse, energetic professionals in a variety of career fields throughout the Unites States. Our mission is to provide safe transportation in the most efficient way possible, while ensuring that our customers get a consistent, high quality experience. Carrying out this mission, and ultimately achieving our vision, hinges on our employees. \n\nThe future rides with us.", "occurrence_notes":null, "guid":"94501-21742778@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/94501", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"", "has_livestream":0, "cost":"", "tags":[], "website":"", "sponsors":[ { "group_name":"University Career Center UCC", "group_id":"1140", "website":"http:\/\/careercenter.umich.edu" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21742778 } , "94843-21776805": { "datetime_modified":"20220427T142801", "datetime_start":"20220509T110000", "datetime_end":"20220509T120000", "has_end_time":1, "date_start":"2022-05-09", "date_end":"2022-05-09", "time_start":"11:00:00", "time_end":"12:00:00", "time_zone":"America\/Detroit", "event_title":"A Multicellular, Biomaterial-based Platform for the Engineering of Vascularized Bone", "occurrence_title":"", "combined_title":"A Multicellular, Biomaterial-based Platform for the Engineering of Vascularized Bone: BME PhD Defense: Nicholas Schott", "event_subtitle":"BME PhD Defense: Nicholas Schott", "event_type":"Presentation", "event_type_id":"16", "description":"Cell-based tissue engineering offers the potential to greatly improve the treatment of large and complex bone defects by addressing the main shortcomings associated with current bone grafting procedures. A main challenge is the ischemic environment that can result from traumatic bone injury, resulting in the death of transplanted cells and tissue constructs. Achieving an adequate vascular supply is a critical barrier preventing the translational success of cell-based regeneration approaches. Therefore, a variety of strategies have been developed to prevascularize engineered tissue constructs prior to transplantation. Adult mesenchymal stromal cells (MSC) and endothelial cells (EC) are key players in native orthopaedic tissue regeneration and vascularization, and represent promising cell types for tissue engineering strategies to create vascularized bone. However, to effectively harness the regenerative potential of MSC, the appropriate phenotype must be achieved before implantation. A main challenge in engineering vascularized bone tissue is creating an appropriate culture environment to support multiple cell phenotypes. Therefore, this work focuses on designing a cell-based, biomaterial-enabled strategy that provides spatiotemporal control of key microenvironmental cues to support the co-development of osseous and vascular tissues, with the end goal of generating vascularized, bone-forming constructs.\r\n\r\nFirst, this thesis explores how temporal control of the culture environment can be used to maintain preformed vessels and subsequent osteogenic development in engineered tissue constructs. To mimic the sequential process of native bone development, in which vascularization precedes tissue ossification, we generated cell-laden hydrogel constructs cultured in vasculogenic growth medium to induce vessel development, and subsequently supplemented the medium with osteoinductive components to promote osteogenic differentiation. Our results revealed conflicting effects of the two culture environments, in which osteoinductive factors compromised cellular viability and MSC pericyte-like function, leading to ~93% regression of preformed vessels. Further, vasculogenic culture conditions inhibited MSC-mediated matrix mineralization as evidenced by impaired calcium deposition.\r\n\r\nNext, this thesis describes the development and characterization of a modular biomaterial approach that provides control of discrete environmental properties designed to promote vasculogenic and osteogenic tissue development. Separate populations of cell-laden microtissues were fabricated and independently cultured under specific differentiation conditions to support either osteogenic or pericyte-like lineage commitment of MSC. This approach enabled the formation of primitive osteogenic microtissues exhibiting mineralization of the extracellular matrix, and vascular microtissues with demonstrated EC sprouting potential. The combination of microtissues led to the generation of a multiphase construct that supported extensive vessel development. While osteogenic activity was maintained without exogenous osteoinductive factors, the vasculogenic culture environment was not conducive for sustained mineralization.\r\n\r\nLastly, this thesis describes a novel approach incorporating the modular biomaterial platform with a biomimetic induction process emulating the native endochondral ossification (EO) pathway to better couple vascular and osteogenic tissue development. Chondrogenically-primed MSC were matured to hypertrophy to form hypertrophic pellets resembling EO, as evidenced by MMP-mediated remodeling and mineralization of the formed cartilaginous matrix. Hypertrophic induction of MSC was associated with secretion of distinct angiogenic factors which stimulated EC vasculogenesis. When combined with vasculogenic microtissues, hypertrophic pellets supported robust vessel development and cell-mediated mineralization without exogenous vasculogenic medium or osteoinductive components.\r\n\r\nOverall, this dissertation presents an attractive strategy for generating vascularized bone-like tissue. By integrating the modular biomaterial platform with an EO-based induction process, we successfully leveraged physiologic cues of hypertrophic MSC to achieve concomitant vasculogenic and osteogenic development.\r\n\r\nDate: Monday, May 9, 2022\r\nTime: 11:00 AM\r\nLocation: 1130 LBME and Zoom (https:\/\/umich.zoom.us\/j\/96133803682 Passcode: bones)\r\nChair: Dr. Jan Stegemann", "occurrence_notes":null, "guid":"94843-21776805@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/94843", "building_id":"1000406", "building_name":"Lurie Biomedical Engineering (formerly ATL)", "campus_maps_id":"7", "room":"1130", "location_name":"Lurie Biomedical Engineering (formerly ATL)", "has_livestream":1, "livestream_type":"zoom", "livetream_require_login":0, "livestream_id":"96133803682", "livestream_password":"bones", "livestream_link":"https:\/\/umich.zoom.us\/j\/96133803682", "cost":"", "tags":["Basic Science","biomedical","biomedical engineering","Biosciences","bme","engineering","Life Science","Medicine","Michigan Engineering"], "website":"", "sponsors":[ { "group_name":"Biomedical Engineering", "group_id":"1143", "website":"https:\/\/www.facebook.com\/profile.php?id=100094127215673" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2022\/04\/event_94843_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_thumb\/media\/attachments\/2022\/04\/event_94843_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2022\/04\/event_94843_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2022\/04\/event_94843_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2022\/04\/event_94843_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2022\/04\/event_94843_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2022\/04\/event_94843_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2022\/04\/event_94843_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large_lightbox\/media\/attachments\/2022\/04\/event_94843_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2022\/04\/event_94843_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2022\/04\/event_94843_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2022\/04\/event_94843_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2022\/04\/event_94843_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2022\/04\/event_94843_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2022\/04\/event_94843_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_thumb\/media\/attachments\/2022\/04\/event_94843_original-1.png" }, "occurrence_count":1, "first_occurrence":21776805 } , "94906-21784746": { "datetime_modified":"20220509T113311", "datetime_start":"20220509T113000", "datetime_end":"20220509T133000", "has_end_time":1, "date_start":"2022-05-09", "date_end":"2022-05-09", "time_start":"11:30:00", "time_end":"13:30:00", "time_zone":"America\/Detroit", "event_title":"Dissertation Defense: Andrew McInnerney", "occurrence_title":"", "combined_title":"Dissertation Defense: Andrew McInnerney: The Argument\/Adjunct Distinction and the Structure of Prepositional Phrases", "event_subtitle":"The Argument\/Adjunct Distinction and the Structure of Prepositional Phrases", "event_type":"Other", "event_type_id":"22", "description":"Linguistics PhD candidate Andrew McInnerney will defend his dissertation on Monday, May 9, at 11:30 am. The title of his dissertation is \u201cThe Argument\/Adjunct Distinction and the Structure of Prepositional Phrases.\u201d Doctoral committee members include Professor Acrisio Pires (Chair), Professor Ezra Keshet, Dr. Lisa Levinson, Professor Richard L. Lewis, and Professor T. Daniel Seely, Eastern Michigan University. All are invited to attend.\r\n\r\nABSTRACT\r\nThis dissertation examines the traditional evidence for the Argument\/Adjunct Distinction (A\/AD). I begin by drawing a distinction between the semantic sense of the A\/AD and the syntactic sense of the A\/AD. The semantic A\/AD concerns lexical encoding of thematic information; arguments are taken to be semantically encoded in the lexical representation of predicates, while adjuncts are not. I argue instead that lexical encoding of thematic information is a property in its own right; the standard evidence does motivate an understanding of the A\/AD in these terms. The syntactic A\/AD has to do with the external syntax of constituents. I consider nine canonical syntactic diagnostics for argumenthood (e.g. omissibility, VP-anaphora, islandhood, etc.), using prepositional phrases in the verbal domain in English as a test case, and I find that these diagnostics do not provide good evidence for the syntactic A\/AD. Instead, the properties identified by the canonical argumenthood diagnostics are independent of one another; they should not be taken to as properties of a single larger distinction. \r\n\tAfter carefully examining the evidence for the A\/AD, I consider the consequences of eliminating the distinction. I focus specifically on consequences for the syntax prepositional phrases, including (i) the configuration of PPs in the verbal domain, (ii) licensing of pronouns within PPs, and (iii) pseudopassives (p-passives). The A\/AD has been argued to play an important role in each of these domains, and so if the distinction is to be eliminated, it is important to explore how analyses in these domains are affected. On the structure of VP-internal PPs, I explore the possibility that PPs could be attached as sisters to functional heads in the verbal domain, potentially forming multiple n-ary-branching layers. On pronoun-licensing in PP, I defend the hypothesis that PP is split into two layers, and I argue that the lower of the two layers is a phase; assuming that Condition B is sensitive to phase domains, this enables an account of a range of relevant data. Finally, on p-passives, I consider the conditions under which p-passivization is blocked, arguing that argumenthood is not a relevant factor.", "occurrence_notes":null, "guid":"94906-21784746@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/94906", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Virtual", "has_livestream":1, "livestream_type":"zoom", "livetream_require_login":0, "livestream_id":"92558400278", "livestream_password":"defense", "livestream_link":"https:\/\/umich.zoom.us\/j\/92558400278", "cost":"", "tags":["Dissertation","Linguistics"], "website":"", "sponsors":[ { "group_name":"Department of Linguistics", "group_id":"3480", "website":"" }, { "group_name":"Weinberg Institute for Cognitive Science", "group_id":"3695", "website":"" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21784746 } , "92924-21698075": { "datetime_modified":"20220419T144316", "datetime_start":"20220509T120000", "datetime_end":"20220509T130000", "has_end_time":1, "date_start":"2022-05-09", "date_end":"2022-05-09", "time_start":"12:00:00", "time_end":"13:00:00", "time_zone":"America\/Detroit", "event_title":"Transfer Bridges Information Session", "occurrence_title":"", "combined_title":"Transfer Bridges Information Session: For Michigan Community College Students", "event_subtitle":"For Michigan Community College Students", "event_type":"Presentation", "event_type_id":"16", "description":"Transfer Bridges to Michigan is an opportunity available only to Michigan community college students. Join us to learn how accessible transferring to LSA can be for high achieving community college students. Transfer Bridges offers tailored support and advising as you plan to transfer, the chance to participate in U-M programs like optiMize and UROP before you transfer, and the opportunity to be mentored by a current LSA transfer student.\r\n\r\nWe will discuss LSA requirements, transfer credit, pre-transfer academic advising, LSA opportunities and other transfer tidbits.\r\n\r\nRegistration is required.", "occurrence_notes":null, "guid":"92924-21698075@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/92924", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Virtual", "has_livestream":1, "livestream_type":"zoom", "livetream_require_login":0, "livestream_id":"92674994998", "livestream_link":"https:\/\/umich.zoom.us\/j\/92674994998", "cost":"", "tags":["Prospective Undergraduate Students","Transfer Students"], "website":"https:\/\/umich.zoom.us\/meeting\/register\/tJYrcO2hpz8jE9yWAOgQ5higs2l6b-Ehslta", "sponsors":[ { "group_name":"LSA Transfer Student Recruitment", "group_id":"4063", "website":"" }, { "group_name":"LSA Transfer Student Center", "group_id":"4442", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2022\/03\/event_92924_original-1.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2022\/03\/event_92924_original-1.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2022\/03\/event_92924_original-1.jpeg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2022\/03\/event_92924_original-1.jpeg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2022\/03\/event_92924_original-1.jpeg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2022\/03\/event_92924_original-1.jpeg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2022\/03\/event_92924_original-1.jpeg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2022\/03\/event_92924_original-1.jpeg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large_lightbox\/media\/attachments\/2022\/03\/event_92924_original-1.jpeg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2022\/03\/event_92924_original-1.jpeg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2022\/03\/event_92924_original-1.jpeg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2022\/03\/event_92924_original-1.jpeg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2022\/03\/event_92924_original-1.jpeg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2022\/03\/event_92924_original-1.jpeg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2022\/03\/event_92924_original-1.jpeg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2022\/03\/event_92924_original-1.jpeg" }, "occurrence_count":1, "first_occurrence":21698075 } , "94743-21763532": { "datetime_modified":"20220524T123050", "datetime_start":"20220509T130000", "datetime_end":"20220509T140000", "has_end_time":1, "date_start":"2022-05-09", "date_end":"2022-05-09", "time_start":"13:00:00", "time_end":"14:00:00", "time_zone":"America\/Detroit", "event_title":"Presidential Management Fellows (PMF) Program Info Session (Accounting\/Finance\/MBA Focus)", "occurrence_title":"", "combined_title":"Presidential Management Fellows (PMF) Program Info Session (Accounting\/Finance\/MBA Focus)", "event_subtitle":"", "event_type":"Careers \/ Jobs", "event_type_id":"2", "description":"https:\/\/opm.zoomgov.com\/meeting\/register\/vJItcuqupjkqE3Uh87K4yFrrN2K3Zai27CA\nAre you an advanced degree student or recent alum who is interested in working in government but unsure where to start? If so, we invite you to come learn about the Presidential Management Fellows (PMF) Program, the Federal Government's premier leadership development program for advanced degree holders (Masters, PhD, JD). The PMF Program is lookingfor eligible students like you with backgrounds in Accounting, Finance,and Business Administration to apply for this unique opportunity to launch your career in government, and we invite you to join us for a 1-hour info session on 5\/9 hosted by the PMF Program Office.\n\nThis info session will provide an overview of the Presidential Management Fellows (PMF) Program, general details about the upcoming application cycle (launching in the fall), and a chance to hear from PMF Alumni (with Accounting, Finance, Business Administration, and related backgrounds) about their experiences in the program. There will also be time for questions toward the end ofthe session. This session is open to graduate students (and recent grads)across all academic disciplines, and will have a specific focus on what the PMF experience looks like for Fellows with backgrounds in Accounting,Finance, Business Administration, and related degrees. Upon registeringfor this session, you will receive an automated email from Zoom with details for accessing the meeting.\n\nThe PMF Program is a two-year fellowship at a Federal agency with full salary and benefits leading to a career inthe Federal Government. Individuals who are in the final year of their advanced degree program or who have finished their advanced degree within the last two years are eligible to apply. The program works with over 100 Federal agencies (such as Treasury, HHS, NASA, USDA, HUD, the State Department, USAID, and many more) to place Fellows according to their interests and skills. By drawing graduate students from diverse social and cultural backgrounds, the PMF Program provides a continuing source of trainedindividuals to meet the future challenges of public service and deliver for the American people. The mission of the PMF Program is to recruit and develop the next generation of Federal Government leaders from all segmentsof society. To learn more, visit www.pmf.gov.\n\nIMPORTANT NOTE ON ELIGIBILITY: From the time of the application launch in fall 2022, individualswho are in the final year of their advanced degree program or who have finished their advanced degree within the last two years are eligible to apply. For the next PMF application, this would likely mean individuals who have completed an advanced degree or expect to complete an advanced degreebetween 10\/2020 to 8\/31\/2023. For additional information on eligibility as it relates to non-U.S. citizens\/international students, visit: https:\/\/www.pmf.gov\/become-a-pmf\/eligibility\/citizenship\/.", "occurrence_notes":null, "guid":"94743-21763532@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/94743", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"", "has_livestream":0, "cost":"", "tags":[], "website":"", "sponsors":[ { "group_name":"University Career Center UCC", "group_id":"1140", "website":"http:\/\/careercenter.umich.edu" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21763532 } , "94880-21780185": 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"combined_title":"Step into a Student Staff Position: Rackham Jobs for Summer and Fall", "event_subtitle":"", "event_type":"Livestream \/ Virtual", "event_type_id":"24", "description":"Rackham has many Graduate Student Staff Assistant (GSSA) job opportunities available in the summer and fall of 2022. Positions are available related to a range of areas, from diversity, equity, and inclusion (DEI) to alumni relations and fundraising. If you are interested in a range of work areas in higher education and would like to develop your skills in the design and implementation of programs for students, faculty, and alumni, these Rackham job opportunities may be of interest to you! Join the Rackham staff who are hiring and supervising GSSAs for an information session to learn more about these opportunities and ask questions.\nRegistration is required at https:\/\/myumi.ch\/6Nx63.\nWe want to ensure full and equitable participation in our events. If an accommodation would promote your full participation in this event, please follow the registration link to indicate your accommodation requirements. Please let us know as soon as possible in order to have adequate time, preferably one week, to arrange for your requested accommodations or an effective alternative.", "occurrence_notes":null, "guid":"94894-21780614@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/94894", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Online", "has_livestream":0, "cost":"", "tags":["Graduate Students"], "website":"https:\/\/rackham.umich.edu\/event\/step-into-a-student-staff-position-rackham-jobs-for-summer-and-fall\/", "sponsors":[ { "group_name":"Rackham Graduate School", "group_id":"1187", "website":"https:\/\/www.facebook.com\/umichgradschool" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21780614 } , "94744-21763533": { "datetime_modified":"20220524T123050", "datetime_start":"20220509T150000", "datetime_end":"20220509T160000", "has_end_time":1, "date_start":"2022-05-09", "date_end":"2022-05-09", "time_start":"15:00:00", "time_end":"16:00:00", "time_zone":"America\/Detroit", "event_title":"Presidential Management Fellows (PMF) Program Info Session (STEM Focus)", "occurrence_title":"", "combined_title":"Presidential Management Fellows (PMF) Program Info Session (STEM Focus)", "event_subtitle":"", "event_type":"Careers \/ Jobs", "event_type_id":"2", "description":"Are you an advanced degree student or recent alum who is interested in working in government but unsure where to start? If so, we invite you to come learn about the Presidential Management Fellows (PMF) Program, the Federal Government's premier leadership development program for advanced degree holders (Masters, PhD, JD). The PMF Program is looking foreligible students like you with backgrounds in STEM to apply for this unique opportunity to launch your career in government, and we invite you tojoin us for a 1-hour info session on 5\/9 hosted by the PMF Program Office.\n\nThis info session will provide an overview of the Presidential Management Fellows (PMF) Program, general details about the upcoming application cycle (launching in the fall), and a chance to hear from PMF Alumni (with STEM backgrounds) about their experiences in the program. There will also be time for questions toward the end of the session. This session is open to graduate students (and recent grads) across all academic disciplines, and will have a specific focus on what the PMF experience looks like for Fellows with backgrounds in STEM. Upon registering for this session, you will receive an automated email from Zoom with details for accessing themeeting.\n\nThe PMF Program is a two-year fellowship at a Federal agency with full salary and benefits leading to a career in the Federal Government. Individuals who are in the final year of their advanced degree program or who have finished their advanced degree within the last two years are eligible to apply. The program works with over 100 Federal agencies (such as HHS, NASA, USDA, the State Department, USAID, and many more) to place Fellows according to their interests and skills. By drawing graduate students from diverse social and cultural backgrounds, the PMF Program provides a continuing source of trained individuals to meet the future challenges of public service and deliver for the American people. The mission of the PMF Program is to recruit and develop the next generation of Federal Government leaders from all segments of society. To learn more, visit www.pmf.gov.\n\nIMPORTANT NOTE ON ELIGIBILITY: From the time of the application launch in fall 2022, individuals who are in the final year of their advanced degree program or who have finished their advanced degree within thelast two years are eligible to apply. For the next PMF application, thiswould likely mean individuals who have completed an advanced degree or expect to complete an advanced degree between 10\/2020 to 8\/31\/2023. For additional information on eligibility as it relates to non-U.S. citizens\/international students, visit: https:\/\/www.pmf.gov\/become-a-pmf\/eligibility\/citizenship\/.", "occurrence_notes":null, "guid":"94744-21763533@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/94744", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"", "has_livestream":0, "cost":"", "tags":[], "website":"", "sponsors":[ { "group_name":"University Career Center UCC", "group_id":"1140", "website":"http:\/\/careercenter.umich.edu" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21763533 } , "94806-21773473": { "datetime_modified":"20220425T142056", "datetime_start":"20220509T160000", "datetime_end":"20220509T180000", "has_end_time":1, "date_start":"2022-05-09", "date_end":"2022-05-09", "time_start":"16:00:00", "time_end":"18:00:00", "time_zone":"America\/Detroit", "event_title":"\"Against Risk-Aversion\u201d- E-WIP\/MMP Talk", "occurrence_title":"", "combined_title":"\"Against Risk-Aversion\u201d- E-WIP\/MMP Talk: Zach Barnett", "event_subtitle":"Zach Barnett", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"Title: \"Against Risk-Aversion\u201d\r\nAbstract: It is widely thought that some degree of risk-aversion is rationally and ethically permissible. For example, in a choice between saving one person for sure and taking a \u00bc chance of saving five people... many believe that we can be permitted to favor the guaranteed rescue over the risky gamble\u2014even though the gamble saves more expected lives. If you attend this talk, you'll hear my best efforts to argue against this consensus. Specifically, it will be argued that non-maximizing risk-aversion conflicts with a conjunction of two attractive principles. The first principle asserts that, if you're comparing two options, and one of them gives a particular person a greater chance of rescue and affects nothing else, then you are required to favor that option. The second principle asserts that if you are required to choose X when the available options are X, Y, and some other alternatives... then you must still be required to choose X when the available options are only X and Y. Finally, it will be discussed how this argument differs from existing arguments against risk-aversion, which traditionally appeal to the fact that the risk-averse agent is likely to lose out in the long run. The argument we'll explore does not rely upon this observation and can be presented in the context of a single decision.", "occurrence_notes":null, "guid":"94806-21773473@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/94806", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":null, "has_livestream":0, "cost":"", "tags":["Philosophy"], "website":"", "sponsors":[ { "group_name":"Department of Philosophy", "group_id":"3186", "website":"http:\/\/www.lsa.umich.edu\/philosophy" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21773473 } , "92835-21697179": { "datetime_modified":"20220425T101118", "datetime_start":"20220509T160000", "datetime_end":"20220509T170000", "has_end_time":1, "date_start":"2022-05-09", "date_end":"2022-05-09", "time_start":"16:00:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"RNA Innovation Seminar: \"Unexpected determinants of neuronal identity and properties: the curious cases of PTBP1, PTBP2, and neuronal splicing\"", "occurrence_title":"", "combined_title":"RNA Innovation Seminar: \"Unexpected determinants of neuronal identity and properties: the curious cases of PTBP1, PTBP2, and neuronal splicing\": Sika Zheng, UC Riverside, School of Medicine", "event_subtitle":"Sika Zheng, UC Riverside, School of Medicine", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"Virtual Seminar via Zoom: https:\/\/umich.zoom.us\/webinar\/register\/WN_dltbxWdHQ5KrC3rTl4hqLQ\r\n\r\nTalk title: \u201cUnexpected determinants of neuronal identity and properties: the curious cases of PTBP1, PTBP2, and neuronal splicing\"\r\n\r\nAbstract: Alternative splicing is the major contributor to transcriptome diversity, but splicing is noisy and to what extend alternative splicing regulation is indispensable for biolgical processes has been controversial. Our studies have revealed the regulation and function of neural-specific splicing in shaping neuronal identity and estalishing neurons\u2019 two unique attributes: 1. Axonogenesis (Only neurons but no other cell types have one and single axon); 2. Neuronal longevity (Neurons are the most long-lived cell types). We show that obtaining these neuronal features is coordinated by RNA binding proteins PTBP1 and PTBP2, while PTBP1 was suggested by others to be a reprogramming factor of neuronal fate. I will discuss the regulatory mechanism of neural specific splicing underlying neurogensis and maturation.\r\n\r\nReferences:\r\nZhang M, Ergin V, Lin L, Stork C, Chen L, Zheng S. Neuron. 2019 Feb 20;101(4):690-706.e10.\r\nErgin V, Zheng S. J Mol Biol. 2020 Jun 26;432(14):4154-4166.\r\nZheng S. Wiley Interdiscip Rev RNA. 2020 Jul;11(4):e1585.\r\nLin L, Zhang M, Stoilov P, Chen L, Zheng S. Neuron. 2020 Sep 23;107(6):1180-1196.e8.\r\nVuong J, Ergin V, Zheng S. Nature Communications (accepted)\r\n\r\nIf you are having trouble registering, please contact Martina Jerant at mjerant@umich.edu", "occurrence_notes":"REGISTRATION: https:\/\/umich.zoom.us\/webinar\/register\/WN_dltbxWdHQ5KrC3rTl4hqLQ", "guid":"92835-21697179@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/92835", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Virtual", "has_livestream":0, "cost":"", "tags":["Biosciences"], "website":"", "sponsors":[ { "group_name":"Center for RNA Biomedicine", "group_id":"4014", "website":"" }, { "group_name":"Biosciences Initiative", "group_id":"4165", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2022\/04\/event_92835_original-2.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2022\/04\/event_92835_original-2.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2022\/04\/event_92835_original-2.jpeg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2022\/04\/event_92835_original-2.jpeg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2022\/04\/event_92835_original-2.jpeg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2022\/04\/event_92835_original-2.jpeg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2022\/04\/event_92835_original-2.jpeg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2022\/04\/event_92835_original-2.jpeg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2022\/04\/event_92835_original-2.jpeg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2022\/04\/event_92835_original-2.jpeg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2022\/04\/event_92835_original-2.jpeg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2022\/04\/event_92835_original-2.jpeg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2022\/04\/event_92835_original-2.jpeg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2022\/04\/event_92835_original-2.jpeg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2022\/04\/event_92835_original-2.jpeg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2022\/04\/event_92835_original-2.jpeg" }, "occurrence_count":1, "first_occurrence":21697179 } , "94873-21778938": { "datetime_modified":"20220524T123055", "datetime_start":"20220509T161500", "datetime_end":"20220509T170000", "has_end_time":1, "date_start":"2022-05-09", "date_end":"2022-05-09", "time_start":"16:15:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"Virtual Networking - 2022 Diversity + Media Career Summit", "occurrence_title":"", "combined_title":"Virtual Networking - 2022 Diversity + Media Career Summit", "event_subtitle":"", "event_type":"Careers \/ Jobs", "event_type_id":"2", "description":"Couldn't attend our 2022 Diversity + Media Career Summit in-person? 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Discovery.\nYou must be either a current student or a recent grad (1-5 years out of school) to participate in this session.\n", "occurrence_notes":null, "guid":"94873-21778938@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/94873", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"", "has_livestream":0, "cost":"", "tags":[], "website":"", "sponsors":[ { "group_name":"University Career Center UCC", "group_id":"1140", "website":"http:\/\/careercenter.umich.edu" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21778938 } , "94510-21744712": { "datetime_modified":"20220504T121540", "datetime_start":"20220509T190000", "datetime_end":"", "has_end_time":0, "date_start":"2022-05-09", "date_end":"", "time_start":"19:00:00", "time_end":"", "time_zone":"America\/Detroit", "event_title":"Women's Golf vs NCAA Ann Arbor Regional", "occurrence_title":"", "combined_title":"Women's Golf vs NCAA Ann Arbor Regional", "event_subtitle":"", "event_type":"Sporting Event", "event_type_id":"20", "description":"Women's Golf vs NCAA Ann Arbor Regional", "occurrence_notes":null, "guid":"94510-21744712@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/94510", "building_id":"1000725", "building_name":"UM Golf Course", "campus_maps_id":"64", "room":"", "location_name":"UM Golf Course", "has_livestream":0, "cost":"", "tags":["Athletics","Athletics - Women's Golf"], "website":"https:\/\/mgoblue.com", "sponsors":[ { "group_name":"Michigan Athletics", "group_id":"3406", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2022\/04\/event_94510_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_thumb\/media\/attachments\/2022\/04\/event_94510_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2022\/04\/event_94510_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_2x\/media\/attachments\/2022\/04\/event_94510_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2022\/04\/event_94510_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2022\/04\/event_94510_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2022\/04\/event_94510_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2022\/04\/event_94510_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large_lightbox\/media\/attachments\/2022\/04\/event_94510_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2022\/04\/event_94510_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2022\/04\/event_94510_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2022\/04\/event_94510_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2022\/04\/event_94510_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2022\/04\/event_94510_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_large\/media\/attachments\/2022\/04\/event_94510_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2022\/04\/event_94510_original-1.png" }, "occurrence_count":1, "first_occurrence":21744712 } }