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BEGIN:VEVENT
DTSTAMP:20230324T120005
DTSTART;TZID=America/Detroit:20220516T000000
DTEND;TZID=America/Detroit:20220516T235959
SUMMARY:Community Service:Homework Help at The Children's Center
DESCRIPTION:The Homework Help program offers children assistance with their homework assignments. Children are encouraged to bring homework and are paired with a volunteer to assist them. This program is a critical service in helping children thrive. Volunteers give children the tools they need to be successful in school.Virtual and in-person volunteer opportunities are available. If you would like to volunteer\, please start the enrollment process by creating an account on the Children Center's Volunteer Site found HERE. After your account is created\, the Children's Center will reach out to you within 2 business days to answer any questions and discuss the next steps.In accordance with the CMS Vaccine Mandate\, those volunteering in-person at the Children’s Center are required to be fully vaccinated and must provide proof of full vaccination upon request.
UID:93885-21787821@events.umich.edu
URL:https://events.umich.edu/event/93885
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:
LOCATION:The Children's Center 
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220515T120005
DTSTART;TZID=America/Detroit:20220516T000000
DTEND;TZID=America/Detroit:20220516T160000
SUMMARY:Other:Regional Tournament
DESCRIPTION:4-team regional tourmanet. Will be playing games Friday-Sunday against Wisconsin\, Michigan State\, and Notre Dame. 
UID:95040-21788382@events.umich.edu
URL:https://events.umich.edu/event/95040
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:
LOCATION:Woodside (Mauston) Sports Complex
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20211129T152100
DTSTART;TZID=America/Detroit:20220516T070000
DTEND;TZID=America/Detroit:20220516T235900
SUMMARY:Careers / Jobs:UROP 2022-2023 Rising Sophomore Applications Open
DESCRIPTION:The Undergraduate Research Opportunity Program is now accepting applications for students who will be rising sophomores during the 2022-2023 academic year.\n\nLearn more and apply today at http://myumi.ch/uropsophomore\n\nRising Sophomore Applications are being accepted on a rolling basis.
UID:89571-21664289@events.umich.edu
URL:https://events.umich.edu/event/89571
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:AEM Featured,Applications,Engineering,Environment,first-generation,Humanities,Interdisciplinary,Life Science,Professional Development,Public Health,Recruiting,Research,research data,Social Sciences,Sophomore,Undergraduate,Undergraduate Students,Urop
LOCATION:Off Campus Location
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220215T154124
DTSTART;TZID=America/Detroit:20220516T080000
DTEND;TZID=America/Detroit:20220516T230000
SUMMARY:Careers / Jobs:Apply to Changing Gears
DESCRIPTION:Changing Gears (CG) is a UROP program designed primarily for community college transfer students who will be attending the University of Michigan\, but also serves students transferring from 4 year institutions. Students in the CG Program become a part of an ongoing faculty-driven research\, scholarly or creative project in their field of interest. Students learn valuable academic skills\, applying these skills to their research project\, academics\, and future career opportunities\, while receiving academic credit or compensation for their efforts in research work.\n\nApplications are accepted on a rolling basis.\nLearn more about Changing Gears at: myumi.ch/uropcg
UID:92406-21690945@events.umich.edu
URL:https://events.umich.edu/event/92406
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:AEM Featured,Applications,first-generation,Free,Interdisciplinary,Networking,Research,research data,Social Impact,The College Of Literature\, Science\, And The Arts,Transfer Students,Undergraduate,Undergraduate Students,Urop
LOCATION:Off Campus Location
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220518T161555
DTSTART;TZID=America/Detroit:20220516T080000
DTEND;TZID=America/Detroit:20220516T160000
SUMMARY:Exhibition:Lane Hall Gallery Summer Exhibit
DESCRIPTION:In this exhibit\, artists Ashley Bigham (photographs) and Grace Mahoney (watercolors) investigate the visibility and social role of Ukraine’s older generation of women embodied in a figure both iconic and ubiquitous: the babusya. Seen in public transport\, in the market\, and on the street\, each babusya has a story to tell. Each has something to say\, something to gossip about\, and something to complain about. \n\n\"Invisible Women: Portraits of Aging in Ukraine\" is hosted by the University of Michigan’s Institute for Research on Women and Gender (IRWG) and the Department of Women’s and Gender Studies. The exhibit is on display for public viewing weekdays from 8:00 a.m.- 4:00 p.m. through August 18\, 2022\, in the main lobby of Lane Hall\, located at 204 South State Street\, Ann Arbor\, MI 48109. For more information on the current exhibit\, visit IRWG’s website.
UID:95140-21788512@events.umich.edu
URL:https://events.umich.edu/event/95140
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Exhibition,institute for research on women and gender,irwg,ukrainian,Women's Studies
LOCATION:Lane Hall
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220419T113622
DTSTART;TZID=America/Detroit:20220516T080000
DTEND;TZID=America/Detroit:20220516T190000
SUMMARY:Exhibition:Mail Art: Postcards from the Pandemic
DESCRIPTION:View postcards from the pandemic. When the U-M Library and the Ann Arbor District Library asked community members to submit handmade postcards — mail art — in 2020 to capture the emotions and experiences of the Ann Arbor and U-M community during challenging pandemic times\, creative pieces of art started arriving at the library. About the submissions: https://myumi.ch/pdbeW\n\nStop by the Hatcher Library to view these physical artifacts that reflect how people were coping during the unexpected Covid-19 shutdown.
UID:94707-21761628@events.umich.edu
URL:https://events.umich.edu/event/94707
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Art,Free,Library
LOCATION:Hatcher Graduate Library - North Lobby (just off the Diag)
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220516T161143
DTSTART;TZID=America/Detroit:20220516T080000
DTEND;TZID=America/Detroit:20220516T190000
SUMMARY:Exhibition:Map ≠ Territory: Distortion and Power in Cartography
DESCRIPTION:More than strict representations of the world we inhabit\, maps are social constructions that embody the interests of their creators. Map ≠ Territory deconstructs maps that have been used to subjugate\, appropriate\, and oppress\, as well as the maps that counter that power through emancipation and advocacy. The exhibit critically engages with materials that span from the colonial era to modern-day Detroit.\n\nThe exhibit is available in the Clark Library (second floor Hatcher) during Hatcher Library hours. Please verify hours on the library's website: https://www.lib.umich.edu
UID:90765-21673607@events.umich.edu
URL:https://events.umich.edu/event/90765
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Library,Maps
LOCATION:Hatcher Graduate Library - Clark Library, 2nd Floor
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220502T122639
DTSTART;TZID=America/Detroit:20220516T080000
DTEND;TZID=America/Detroit:20220516T230000
SUMMARY:Careers / Jobs:UROP First-Year Application Open
DESCRIPTION:Our \"Traditional UROP Program\" has been our flagship program running over 30 years. This Academic Year program\, in which students participate for both Fall and Winter Terms\, is designed for University of Michigan first and second year undergraduate students enrolled on the Ann Arbor campus who are seeking a first time research experience. Student research assistants work alongside a faculty member\, research scientist or professional practitioner on an ongoing or new research project.\n\nLearn more and apply at: myumi.ch/uropyearone\n\nApplications being accepted on a rolling basis.
UID:83923-21785170@events.umich.edu
URL:https://events.umich.edu/event/83923
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:AEM Featured,Applications,first-generation,Free,Interdisciplinary,Networking,Research,Undergraduate,Undergraduate Students,Urop
LOCATION:
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220117T095807
DTSTART;TZID=America/Detroit:20220516T080000
DTEND;TZID=America/Detroit:20220516T230000
SUMMARY:Careers / Jobs:UROP Research Scholars Program Application Open
DESCRIPTION:The UROP Research Scholars Program is designed for students who want to expand on their first year UROP experience and participate in UROP for a second year at an advanced level. In this program\, students build upon the knowledge gained in a first undergraduate research experience to further explore the connections between research\, a liberal arts education\, and communicating skills to advance their future professional goals. Students are expected to explore various written and oral possibilities for communicating their research process\, identifying the limits set by the discipline and the opportunities that lie beyond.\n\nApplications for the 2022-2023 academic year cohort open February 14th.\nPriority Deadline for the applications is March 18th\n\nLearn more at: myumi.ch/uroprs
UID:91080-21676529@events.umich.edu
URL:https://events.umich.edu/event/91080
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:AEM Featured,Applications,Fellowship,first-generation,Interdisciplinary,Networking,Research,research data,Sophomore,The College Of Literature\, Science\, And The Arts,Undergraduate,Undergraduate Students,Urop
LOCATION:Off Campus Location
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220810T112545
DTSTART;TZID=America/Detroit:20220516T090000
DTEND;TZID=America/Detroit:20220516T100000
SUMMARY:Livestream / Virtual:Culture Journey Community Assembly: Restoring Trust and Building for the Future
DESCRIPTION:Please join us for the Culture Journey Community Assembly Zoom webinar on Monday\, May 16 from 9-10 am to learn what the Culture Change Values Identification Working Group has discovered thus far to promote culture change.\n\nFeatured speakers include:\nU-M President Mary Sue Coleman\nProvost-Elect Laurie McCauley\n\nCulture Change Values Identification Working Group Co-Chairs:\nDean Patricia Hurn and Chief Organizational Learning Officer Sonya Jacobs\n\nLearn how:\nWe're identifying values that will be foundational to promote culture change at U-M\nCulture change partners are connecting across campus\nCulture change work is progressing and what we've learned so far\nYou can engage in next steps along the journey\n\nU-M leaders and culture journey partners also want to hear from you. This event will include a Q&A session for the U-M community to share ideas\, feedback and questions about our culture journey. The assembly will be recorded and shared for those who can't attend. Captioning will be provided. If you require additional accommodations to participate\, please contact orglearningemail@umich.edu.
UID:95101-21788468@events.umich.edu
URL:https://events.umich.edu/event/95101
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Culture,Diversity,Diversity Equity and Inclusion,Inclusion
LOCATION:Off Campus Location - https://umich.zoom.us/j/93148425394
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220204T165932
DTSTART;TZID=America/Detroit:20220516T090000
DTEND;TZID=America/Detroit:20220516T180000
SUMMARY:Exhibition:Greek Manuscripts at the University of Michigan Library: A Celebration
DESCRIPTION:Splendors of the religious and artistic endeavors of Byzantine manuscript makers are on display in this exhibit of highlights from the Greek manuscript collection at the University of Michigan Library Special Collections Research Center. The collection — 110 codices (bound manuscripts) and fragments written in Greek from the fourth to the nineteenth centuries C.E. — is the largest such collection in the Western Hemisphere and provides unique insights into this era of achievement in textual transmission\, calligraphy\, illumination\, and bookbinding. The exhibit will be open during Audubon Room hours.\n\nA digital version of the exhibit will be available in the Audubon Room and online\, and allows visitors to explore other pages of the manuscripts on display and other manuscripts from the collection.\n\nThis exhibit celebrates two recent publications based on the collection: \n\n* Catalogue of Greek Manuscripts at the University of Michigan\, Ann Arbor. Vol. 1.\, by Nadezhda Kavrus-Hoffmann (Ann Arbor: University of Michigan Press\, 2021)\n\n* Tradition and Individuality: Bindings from the University of Michigan Greek Manuscript Collection\, by Julia Miller (Ann Arbor: The Legacy Press\, 2021)
UID:92000-21684913@events.umich.edu
URL:https://events.umich.edu/event/92000
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Classical Studies,Exhibition,Library
LOCATION:Hatcher Graduate Library - Audubon Room, 1st floor
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220428T133525
DTSTART;TZID=America/Detroit:20220516T100000
DTEND;TZID=America/Detroit:20220516T110000
SUMMARY:Lecture / Discussion:Roles for GLI Transcription Factors in Pancreas Development and Disease
DESCRIPTION:Dissertation Defense\n\nWe are pleased to announce that Michael Scales will present his Dissertation Defense on \"Roles for GLI Transcription Factors in Pancreas Development and Disease\" on Monday\, May 16\, 2022\, at 10:00 a.m.\, in person at Forum Hall\, Palmer Commons\, and via live stream: \n\nMeeting Link:  Link: https://umich.zoom.us/j/93788826971 Passcode: GLI\n\nHosted By the Dissertation Committee:\nBenjamin Allen\, Ph.D. - Co-mentor\nMarina Pasca di Magliano\, Ph.D. - Co-mentor\nAndrzej Dlugosz\, M.D. - Chair\nDeneen Wellik\, Ph.D.\nHoward Crawford\, Ph.D.
UID:94798-21771366@events.umich.edu
URL:https://events.umich.edu/event/94798
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Basic Science,Biology,Biosciences,Science
LOCATION:Palmer Commons
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220531T063026
DTSTART;TZID=America/Detroit:20220516T110000
DTEND;TZID=America/Detroit:20220516T120000
SUMMARY:Careers / Jobs: NNSA Graduate Fellowship Program Virtual Information Session – May 16\, 2022
DESCRIPTION:Are you a curious person looking for a fulfilling and impactful career? Do you seek to address challenges at the forefront of our national security landscape? Whether you are majoring in business\, the sciences\, policy\, or engineering\, the NNSA Graduate Fellowship Program may havean opportunity for you! Join us to learn more at: https://tinyurl.com/2p8sp236\n\nThe fellowship gives highly motivated\, graduate-level students afull year of:\n• Real-world experience to prepare for a career in national security \n• Opportunities to make significant contributions to the nation \n• Specialized training\, leadership and career development\, and networking \n• Collaboration with professionals and leading researchers worldwide\n\nThe fellowship is a 12-month\, salaried position working with NNSA program offices in Washington D.C. or at one of the NNSA site locations nationwide. These fellowships are open to students actively pursuingtheir master’s or doctoral degree as well as students who have completed their graduate degree on or after April 7\, 2021. Details about the program can be found on at https://www.pnnl.gov/projects/ngfp. The current application deadline is October 7\, 2022 for positions that will begin in June 2023.\n
UID:93292-21702255@events.umich.edu
URL:https://events.umich.edu/event/93292
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:
LOCATION:
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220505T145812
DTSTART;TZID=America/Detroit:20220516T120000
DTEND;TZID=America/Detroit:20220516T133000
SUMMARY:Lecture / Discussion:Inspiring Justice-Driven Educational Research through Critical History and Storytelling
DESCRIPTION:The histories we learn and the stories we tell – of our country\, of our community\, of ourselves – are situated within the struggles for social justice\, civil rights\, and human dignity. Though stories have been used to disparage and perpetuate harm\, stories can also be used to humanize\, theorize\, and resist. When we critically engage with history and center the stories of peoples and groups on the margins\, we not only counter erasure\, but also pave paths toward justice. As such\, stories are a source of power.\n\nModerated by a third-generation storyteller\, education scholars will come together to discuss how they have integrated critical history and storytelling into their scholarship\, teaching\, and community engagement. We look forward to gathering for an enriching event that we hope will inspire and inform others’ efforts to learn from and with communities to advance justice-driven educational research.\n\nThis event is part of the CREATE (Community-based Research on Equity\, Activism\, & Transformative Education) Center’s Community Engaged Speaker Series and is co-sponsored by the National Center for Institutional Diversity and the Ginsberg Center for Community Service and Learning at the University of Michigan.\n\nModerator\n\nElizabeth James\, Program Associate for the Department of Afroamerican and African Studies at the University of Michigan & Third-Generation Storyteller\n\nPanelists\n\nSirrita Darby\, Co-Founder and Executive Director of Detroit Heals Detroit\n\nJamon Jordan\, Detroit City Historian & Founder of the Black Scroll Network\n\nTonya Kneff-Chang\, Postdoctoral Researcher at the Center for Community-based Research on Equity\, Activism\, & Transformational Education
UID:94992-21788225@events.umich.edu
URL:https://events.umich.edu/event/94992
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:AEM Featured,Diversity Equity and Inclusion
LOCATION:Off Campus Location
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220531T063031
DTSTART;TZID=America/Detroit:20220516T120000
DTEND;TZID=America/Detroit:20220516T130000
SUMMARY:Careers / Jobs:SMBC Meet and Greet (Debt Capital Markets\, Leveraged and Acquisition Finance\, Loan Syndications)
DESCRIPTION:Event Description:\nOur SMBC Meet and Greet Series is a uniqueopportunity to meet and interact with the various business areas that hire interns and analysts. This session will feature overviews of three business groups followed by a Q&A session.\n\nNote: You are welcome to attend as many of the Meet and Greet sessions as you like. You can find each session’s participating business groups on our events central page here. \n\n\nDebt Capital Markets (DCM)                    \nSMBC Nikko’s Debt Capital Markets (DCM) group focuses on debt origination\, structuring\, and execution across a variety ofsecurities\, ratings categories\, industries\, and currencies. The team works closely with Syndicate and other related products as well as Corporate & Investment Banking (client coverage/relationship management) to service SMBC’s issuer fixed income needs.\n\n \n\nLoan Syndications (LCM) + Leveraged and Acquisition Finance Group (LAFG)\nThe Loan Capital Markets (LCM) Department is responsible for the structuring\, underwriting\, execution and distribution of syndicated loan transactions across all industry andorigination groups at SMBC. LCM professionals work with and advise the front office marketing (origination) units in order to successfully pitch corporate and financial sponsor clients in a combined effort to win lead-mandates for syndicated loan facilities. Proposals to prospective clients usually involve coordination and partnership with other SMBC and Nikko (our Securities unit) product groups (Debt Capital Markets\, FX\, Derivatives Marketing and so on) in order to provide comprehensive\, multiproduct financing solutions to our clients. Once a lead mandate for a syndicated loan isreceived\, the LCM team is responsible for execution and distribution of loans to both banks and institutional investors.\n\nLeveraged Finance is aclient-facing division of Sumitomo Mitsui Banking Corporation\, responsible for delivering the full front-to-back spectrum of lead leveraged loan and high yield bond solutions to our client base including\, private equitysponsors and their portfolio companies and non-Investment grade corporates. Leveraged & Acquisition Finance interacts with bank and institutional clients via its Sales & Trading desks within the broader Loan Capital Markets and Nikko Fixed Income platforms.\n\n \nInfo Session Details:\nLocation: https://smbc.webex.com/smbc/j.php?MTID=md9a8b23550af440501ff8c91ea8ed9f4\nMeeting Number: 2632 851 9831\nMeeting Password: Spring123
UID:94860-21777279@events.umich.edu
URL:https://events.umich.edu/event/94860
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:
LOCATION:
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220429T123103
DTSTART;TZID=America/Detroit:20220516T120000
DTEND;TZID=America/Detroit:20220516T130000
SUMMARY:Careers / Jobs:SMBC Meet and Greet (Debt Capital Markets\, Leveraged and Acquisition Finance\, Loan Syndications)
DESCRIPTION:Event Description:\nOur SMBC Meet and Greet Series is a uniqueopportunity to meet and interact with the various business areas that hire interns and analysts. This session will feature overviews of three business groups followed by a Q&A session. \n\nNote: You are welcome to attend as many of the Meet and Greet sessions as you like. You can find each session’s participating business groups on our events central page here. \n\nDebt Capital Markets (DCM)                  \nSMBC Nikko’s Debt Capital Markets (DCM) group focuses on debt origination\, structuring\, and execution across a variety of securities\, ratings categories\, industries\, and currencies. The team works closely with Syndicate and other related products as well as Corporate & Investment Banking (client coverage/relationship management) to service SMBC’s issuer fixed income needs.\n\nLoan Syndications (LCM) + Leveragedand Acquisition Finance Group (LAFG)\nThe Loan Capital Markets (LCM) Department is responsible for the structuring\, underwriting\, execution and distribution of syndicated loan transactions across all industry and origination groups at SMBC. LCM professionals work with and advise the front office marketing (origination) units in order to successfully pitch corporateand financial sponsor clients in a combined effort to win lead-mandates for syndicated loan facilities. Proposals to prospective clients usually involve coordination and partnership with other SMBC and Nikko (our Securities unit) product groups (Debt Capital Markets\, FX\, Derivatives Marketingand so on) in order to provide comprehensive\, multiproduct financing solutions to our clients. Once a lead mandate for a syndicated loan is received\, the LCM team is responsible for execution and distribution of loans to both banks and institutional investors.\n\nLeveraged Finance is a client-facing division of Sumitomo Mitsui Banking Corporation\, responsible for delivering the full front-to-back spectrum of lead leveraged loan and highyield bond solutions to our client base including\, private equity sponsors and their portfolio companies and non-Investment grade corporates. Leveraged & Acquisition Finance interacts with bank and institutional clients via its Sales & Trading desks within the broader Loan Capital Markets and Nikko Fixed Income platforms.\n\nInfo Session Details:\nLocation: https://smbc.webex.com/smbc/j.php?MTID=md9a8b23550af440501ff8c91ea8ed9f4\nMeeting Number: 2632 851 9831\nMeeting Password: Spring123
UID:94883-21780186@events.umich.edu
URL:https://events.umich.edu/event/94883
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:
LOCATION:
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220506T154157
DTSTART;TZID=America/Detroit:20220516T150000
DTEND;TZID=America/Detroit:20220516T170000
SUMMARY:Reception / Open House:Baldwin Prize Ceremony
DESCRIPTION:On Monday\, May 16\, CLaSP PhD Dr. Yeimy Rivera will receive the Ralph B. Baldwin Prize in Astrophysics and Space Sciences in an award ceremony and reception.\n\nThe Baldwin Prize is an award sponsored by a generous gift to the University by Dr. Ralph B. Baldwin. Applicants must show original and significant contributions to their field as measured in their scholarly publications.\n\nStudent applications are selected from the fields of Astronomy\, Atmospheric\, Oceanic\, and Space Science\; Chemistry\; Physics\; Geology\; and Mathematics as they pertain to space\, its bodies\, and relevant physical processes. The prize is awarded annually to a student who has received a University of Michigan Ph.D. during the previous year. A faculty committee comprised of representatives from the appropriate departments judges the packages submitted on the basis of the excellence of their research activities revealed in the student’s thesis and publications during their career.
UID:95018-21788271@events.umich.edu
URL:https://events.umich.edu/event/95018
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:astrophysics,Climate and Space Sciences and Engineering
LOCATION:Climate and Space Research Building - 2249
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220418T172323
DTSTART;TZID=America/Detroit:20220516T160000
DTEND;TZID=America/Detroit:20220516T170000
SUMMARY:Lecture / Discussion:RNA Innovation Seminar: \"An Academic Approach to Oligonucleotide Therapeutics\"
DESCRIPTION:In-person: BSRC\, ABC seminar rooms\nLivestream: https://myumi.ch/9Py8b\n\nTalk title: “An Academic Approach to Oligonucleotide Therapeutics”\n\nKeywords: Oligonucleotides\, Chemical Modifications\, RNA\, Huntington’s Disease\n\nAbstract: Nucleic acids (NA) are becoming the third major pillar of therapeutic modalities on par with small molecules and biologics. The diversity of NA molecular mechanisms\, ranging from vaccines\, antisense\, short interfering RNA (siRNAs)\, and guide RNA for CRISPR gene editing systems\, enable impact on most aspects of cellular biology and thus human medicine. The foundation behind the recent oligonucleotides' clinical success is fundamental chemical innovations in RNA stability\, delivery\, and synthesis. \nOligonucleotides are informational drugs\; thus\, if chemical architectures supporting safe and efficient delivery to the tissue of interest are achieved\, they can be easily reprogrammed to modulate any gene expression on demand\, creating an opportunity for academic institutions to drive therapeutic innovation. However\, the process is limited by access to oligonucleotide chemistry and synthetic expertise. \nIn the first half of the talk\, I will share the experience of building and running Nucleic Acid Chemistry Center in a context of a large academic institution. The NACC provides access to therapeutic quality screening leads and large manufacturing of preclinical compounds for the academic community. The impact of the NACC and chemical innovation will be discussed in the context of two significant projects. First\, I will discuss the systematic structure-activity relationship study of chemical modifications to modulate RISC loading and cleavage. Screening 1200 siRNA variants allow for defining the chemical and thermodynamic rules for RISC assembly.\nA recent discovery from our lab has identified di-valent siRNA as a scaffold enabling potent and sustained modulation of gene expression in CNS of rodents and NHP with multiple compounds advancing clinic. Recently\, somatic repeat expansion has been identified as the driver behind many repeat-associated disorders. Indeed\, modulation of MSH3\, an essential gene involved in long repeat expansion\, blocked somatic repeat expansion in the Q111 model of Huntington's Disease. I would present how access to NACC allowed the development and validation of the clinical lead and define a novel therapeutic approach for the treatment of HD.\n\n\nIf you are having trouble registering\, please contact Martina Jerant at mjerant@umich.edu
UID:92837-21697182@events.umich.edu
URL:https://events.umich.edu/event/92837
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biosciences
LOCATION:Taubman Biomedical Science Research Building - ABC Seminar Room
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20220531T123031
DTSTART;TZID=America/Detroit:20220516T160000
DTEND;TZID=America/Detroit:20220516T170000
SUMMARY:Careers / Jobs:SMBC Meet and Greet (Equity Capital Markets\, Equities Execution Group\, Investment Banking Advisory\, Strategic Credit Products\, Fixed Income Sales & Trading)
DESCRIPTION:Event Description:\nOur SMBC Meet and Greet Series is a uniqueopportunity to meet and interact with the various business areas that hire interns and analysts. This session will feature overviews of five business groups followed by a Q&A session.\n\nNote: You are welcome to attend asmany of the Meet and Greet sessions as you like. You can find each session’s participating business groups on our events central page here. \n\nEquity Capital Markets (ECM)\nOur rapidly expanding Equity Capital Markets (ECM) team offers equity and equity-linked financing solutions to corporate and project finance clients in the U.S. The experienced team is committed to a track record of client-centric excellence\; providing products suchas initial public offerings (“IPO”)\, follow-on offerings (“FO”)\, convertible offerings\, at-the-market offerings (“ATMs”) and share repurchase programs to our clients. In addition to origination capabilities\, the ECM team provides exceptional execution by our seasoned syndicate professionals.\n\nEquities Execution Group\nEquity Execution Services Group(EESG) is the equity sales and trading department of SMBC Nikko Americas\, Inc.\, a full-service brokerage firm. Our desk is composed of traders and sales traders each with decades of experience in US and other equity markets\, as well as experience in equity-related products such as derivatives\, electronic trading\, program trading\, proprietary trading\, trading systems and fundamental analysis.  We have extensive client relationships in North America and the rest of the world\, and at this firm nurture and grow existing and new relationships with our unique market color and platform offering. This desk offers exposure to not only the secondary (public) side of sales and trading\, but also insights into the Japanese client base\, as well as corporate activities. \n\nInvestment Banking Advisory (IBA)\nInvestment Banking Advisory advises SMBC and SMBC Nikko’s global clients\, specializing in strategic and financial advisory\, including M&A and capital markets\, across multiple sectors such as Consumer & Retail\, Power & Infrastructure\, Industrials and TMT. \n\nStrategic Credit Products (SCAD)\nThe Strategic Credit Products Department\, Americas Division (SCAD) offers leveraged financed solutions to clients including Private Equity firms related to large-cap and middle market LBO transactions and to supportAsset Manager clients including large BDCs and other institutional lenders involved in middle market leveraged finance transactions. The group arranges\, structures\, distributes and holds a portion of risk on all of its transactions. Products include leveraged and syndicated loans\, fixed income\, securitization and asset backed financings.  \n\nFixed Income Sales &Trading (FIST)\nSMBC Nikko’s Fixed Income Sales and Trading (FIST) offers a broad range of investment services specifically tailored for institutional investors. Staffed with highly experienced and knowledgeable professionals\, our Fixed Income team offers deep economic insight\, a wide arrayof product offerings\, and seamless execution across a wide variety of markets. Our product line includes a broad range of Corporate\, Asset-Backed\, and Government Securities in addition to Project Finance\, Repo and other Fixed Income instruments. The team is dedicated to providing superior solutions to the unique return and risk management needs of our clients.\n\nInfo Session Details:\nLocation: https://smbc.webex.com/smbc/j.php?MTID=mebafe318319ee5220529c3b24aa076da\nMeeting Number: 2631 736 4721\nMeeting Password: Spring123
UID:94885-21780188@events.umich.edu
URL:https://events.umich.edu/event/94885
CLASS:PUBLIC
STATUS:CONFIRMED
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