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        "event_title":"Homework Help at The Children's Center",
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        "combined_title":"Homework Help at The Children's Center",
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        "description":"The Homework Help program offers children assistance with their homework assignments. Children are encouraged to bring homework and are paired with a volunteer to assist them. This program is a critical service in helping children thrive. Volunteers give children the tools they need to be successful in school.Virtual and in-person volunteer opportunities are available. If you would like to volunteer, please start the enrollment process by creating an account on the Children Center's\u00a0Volunteer Site found HERE.\u00a0After your account is created, the Children's Center will reach out to you within 2 business days to answer any questions and discuss the next steps.In accordance with the CMS Vaccine Mandate, those volunteering in-person at the Children\u2019s Center are required to be fully vaccinated and must provide proof of full vaccination upon request.",
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        "event_title":"UROP 2022-2023 Rising Sophomore Applications Open",
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        "combined_title":"UROP 2022-2023 Rising Sophomore Applications Open",
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        "description":"The Undergraduate Research Opportunity Program is now accepting applications for students who will be rising sophomores during the 2022-2023 academic year.\r\n\r\nLearn more and apply today at http:\/\/myumi.ch\/uropsophomore\r\n\r\nRising Sophomore Applications are being accepted on a rolling basis.",
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        "time_zone":"America\/Detroit",
        "event_title":"Apply to Changing Gears",
        "occurrence_title":"",
        "combined_title":"Apply to Changing Gears: Research experience for Transfer Students",
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        "description":"Changing Gears (CG) is a UROP program designed primarily for community college transfer students who will be attending the University of Michigan, but also serves students transferring from 4 year institutions. Students in the CG Program become a part of an ongoing faculty-driven research, scholarly or creative project in their field of interest. Students learn valuable academic skills, applying these skills to their research project, academics, and future career opportunities, while receiving academic credit or compensation for their efforts in research work.\r\n\r\nApplications are accepted on a rolling basis.\r\nLearn more about Changing Gears at: myumi.ch\/uropcg",
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        "website":"https:\/\/lsa.umich.edu\/urop\/Prospective-Students\/fall-winter-programs\/changing-gears-program.html",
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        "event_title":"Lane Hall Gallery Summer Exhibit",
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        "combined_title":"Lane Hall Gallery Summer Exhibit: \"Invisible Women: Portraits of Aging in Ukraine\" Photographs by Ashley Bigham and Watercolors by Grace Mahoney",
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        "description":"In this exhibit, artists Ashley Bigham (photographs) and Grace Mahoney (watercolors) investigate the visibility and social role of Ukraine\u2019s older generation of women embodied in a figure both iconic and ubiquitous: the babusya. Seen in public transport, in the market, and on the street, each babusya has a story to tell. Each has something to say, something to gossip about, and something to complain about. \r\n\r\n\"Invisible Women: Portraits of Aging in Ukraine\" is hosted by the University of Michigan\u2019s Institute for Research on Women and Gender (IRWG) and the Department of Women\u2019s and Gender Studies. The exhibit is on display for public viewing weekdays from 8:00 a.m.- 4:00 p.m. through August 18, 2022, in the main lobby of Lane Hall, located at 204 South State Street, Ann Arbor, MI 48109. For more information on the current exhibit, visit IRWG\u2019s website.",
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                "website":"http:\/\/www.ii.umich.edu\/crees"                },             {
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        "datetime_start":"20220613T080000",
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        "time_start":"08:00:00",
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        "event_title":"Map \u2260 Territory: Distortion and Power in Cartography",
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        "combined_title":"Map \u2260 Territory: Distortion and Power in Cartography",
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        "datetime_end":"20220613T230000",
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        "date_start":"2022-06-13",
        "date_end":"2022-06-13",
        "time_start":"08:00:00",
        "time_end":"23:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"UROP First-Year Application Open",
        "occurrence_title":"",
        "combined_title":"UROP First-Year Application Open",
        "event_subtitle":"",
        "event_type":"Careers \/ Jobs",
        "event_type_id":"2",
        "description":"Our \"Traditional UROP Program\" has been our flagship program running over 30 years. This Academic Year program, in which students participate for both Fall and Winter Terms, is designed for University of Michigan first and second year undergraduate students enrolled on the Ann Arbor campus who are seeking a first time research experience. Student research assistants work alongside a faculty member, research scientist or professional practitioner on an ongoing or new research project.\r\n\r\nLearn more and apply at: myumi.ch\/uropyearone\r\n\r\nApplications being accepted on a rolling basis.",
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        "description":"Analysis of Complex Sample Survey Data\r\n\r\nOpen for registration!\r\n\r\nJune 6 - July 29, 2022\r\n10:00am-12:00pm\r\nM\/W\/F\r\n\r\nThis course provides practical methods and tools to analyze complex survey data with a hands-on introduction to the use of specialized statistical software procedures. The course focuses on case studies with specific large-scale national surveys: the National Comorbidity Survey-Replication (NCS-R), the National Health and Nutrition Examination Surveys (NHANES), and the Health and Retirement Study (HRS). Relevant design features of the NCS-R, NHANES and HRS include survey weights that take into account differences in probability of selection into the sample and differences in response rates, as well as stratification and clustering in the multistage sampling procedures used in identifying the sampled households and individuals. After introducing essential concepts related to complex sample designs, the course will turn to the construction of survey weights, estimation of sampling variance, descriptive analysis, regression analysis, and finally special topics in the analysis of survey data. Participants can expect to work on homework exercises, computer lab exercises, and a final analysis project.\r\n\r\nWhy take this course? \r\n- To gain an understanding of modern methods and software for the secondary analysis of survey data collected from large complex samples\r\n- To have the opportunity for one-on-one interaction with the instructors when walking through analyses of survey data\r\n- To see various examples of applied statistical analyses of survey data\r\n- To have the experience of writing a scientific paper that presents an analysis of complex sample survey data, and getting expert feedback on that paper.\r\n\r\nCourse Hours: 3\r\n\r\nInstructors: Brady T. West, Yajuan Si\r\n\r\nPrerequisite: Two graduate-level courses in statistical methods, familiarity with basic sample design concepts, and familiarity with data analytic techniques such as linear and logistic regression.\r\n\r\nAll 2022 courses will be offered in an alternative remote format.",
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        "time_zone":"America\/Detroit",
        "event_title":"Summer Institute in Survey Research Techniques",
        "occurrence_title":"",
        "combined_title":"Summer Institute in Survey Research Techniques: Courses and Workshops, June 6-July 29, 2022",
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        "description":"Open for registration!\r\n\r\nThe Summer Institute offers courses on (1) research design and sample selection, (2) measurement, (3) qualitative methods in survey research design, (4) data collection, and (5) analysis.\r\n\r\nMulti-week courses provide more in-depth coverage of a topic, include readings, homework, and examinations, and often providing participants with an opportunity to practice survey techniques.  One-week courses give an overview of a methodology topic, including readings and homework.  One-day workshops are offered for those who need to learn a specific technique or method in a short period of time.\r\n\r\nAll 2022 courses will be offered in an alternative remote format.",
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        "datetime_modified":"20220607T092242",
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        "event_title":"BME PhD Defense: Feiran Li",
        "occurrence_title":"",
        "combined_title":"BME PhD Defense: Feiran Li: Cell Therapy and Immunomodulation for Type 1 Diabetes",
        "event_subtitle":"Cell Therapy and Immunomodulation for Type 1 Diabetes",
        "event_type":"Lecture \/ Discussion",
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        "description":"Cell-based therapies are emerging for Type I diabetes mellitus (T1D), an autoimmune disease characterized by the destruction of insulin producing pancreatic \u03b2-cells, as a means to provide long term restoration of glycemic control. The limited supply of donor islets has motivated research into methods for differentiating pancreatic \u03b2-cells from renewable pluripotent stem cells such as human pluripotent stem cells (hPSCs). Biomaterial scaffolds maintain the integrity of cell-to-cell and cell-to-matrix connections by avoiding the disruption of the cell niche during handling. This dissertation addresses three key questions with respect to cell therapy and immunomodulation for T1D, including culture system on porous PLG scaffold, functionalized scaffold for improved cell viability and maturation, and immunomodulation with the membrane coated nanoparticles (MCNPs).\r\n\r\nCulture on porous biomaterial scaffolds of hPSCs was investigated at multiple stages of differentiation between Stage 0 and 6 for improved differentiation. Scaffolds are biomaterial devices that could provide chemical and physical cues to control the microenvironment and subsequently alter cellular behavior by facilitating cell-cell interactions. The culture of cells on the scaffolds was found to support maturation of SC derived beta cells depending on the stage of seeding. Suspension cultured-pancreatic progenitors seeded onto scaffolds for stage 5 culture (pancreatic endocrine development), demonstrated enhanced expression for many maturation genes compared to cells that remained in suspension culture through the end of stage 6. This study showcased the scaffold culture as a promising platform for maturation that allows cells to develop a niche and may allow for direct transplantation without manipulating cells.\r\n\r\nEarly engraftment and development of \u03b2-cells post transplantation are a major limitation for stem cell derived beta cells due in part to their being immature. The survival and development of hPSC-derived \u03b2-cells seeded onto PLG microporous scaffolds were investigated within the initial 2 weeks post transplantation. Early inflammatory events induced by the biomaterial and transplanted cells heavily affected hPSC-derived \u03b2-cell engraftment due to the innate immune response. The inflammation includes the production of soluble mediators, inflammatory cytokines and the recruitment of innate cells at the graft site, hindering early graft engraftment and in-vivo hPSC-derived \u03b2-cell maturation. The PLG-based biodegradable scaffold chemically linked with a novel form of FasL chimeric with streptavidin, SA-FasL, was applied to create an immunoprivileged transplant site by modulating the local inflammatory microenvironment. The \u03b2-cell viability and differentiation were found improved at the SA-FasL induced immunoprivileged site together with a suppressed inflammatory reaction.\r\n\r\nLife-long systemic immune suppression due to allogenic graft\/cell transplant also limits the translation of cell therapies for T1D. We investigated the design of membrane-coated nanoparticles (MCNPs), with membranes derived from bone marrow-derived dendritic cells and coated onto poly(lactic-co-glycolic acid) (PLGA) nanoparticle cores, to directly interact with both na\u00efve and activated T cells. Mechanistic studies revealed that the developed MCNPs have the capability to communicate with allogenic T cells by modulating the cytokine secretion levels similar to professional antigen presenting cells. Furthermore, the MCNPs can be engineered pre- and post-fabrication for upregulated surface molecules or varied antigen binding and can be functionalized by biotinylation for a wider range of protein loading.\r\n\r\nOverall, this dissertation discussed optimization and early immunomodulation of the biomaterial culturing system for hPSC-derived \u03b2 cells, and development of tunable MCNPs for direct T cell communication.\r\n\r\nDate: Monday, June 13, 2022\r\nTime: 12:00 PM\r\nLocation: NCRC Building 520 Room 1122 and Zoom (https:\/\/umich.zoom.us\/j\/93840656651)\r\nChair: Dr. Lonnie Shea",
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        "event_title":"Introduction and Welcome to Multi-Ethnic Student Affairs (MESA)",
        "occurrence_title":"",
        "combined_title":"Introduction and Welcome to Multi-Ethnic Student Affairs (MESA)",
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        "description":"Using the lens of race and ethnicity, MESA engages the campus community and transforms the student experience to build inclusive spaces and equitable opportunities for all. Our work manifests in many cultural and educational events\/programs, and leadership and development opportunities. Come and get to know MESA and learn how you can get involved. We are looking forward to meeting and welcoming you to the University of Michigan. Go Blue!",
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        "datetime_modified":"20220608T143337",
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        "event_title":"Navigating Disability in 19th-Century America",
        "occurrence_title":"",
        "combined_title":"Navigating Disability in 19th-Century America: Student Curated Exhibit",
        "event_subtitle":"Student Curated Exhibit",
        "event_type":"Exhibition",
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        "description":"The four display cases in this exhibit were curated by members of a combined undergraduate and graduate course on disability history and literature at the University of Michigan to convey what it was like to be disabled in the United States before the modern category of \u201cdisability\u201d existed. Together, the artifacts gathered from the Clements Library collections provide a glimpse of the cruelties, triumphs, and intimate acts of care that shaped the lives of people with disabilities in the past. \r\n \r\nThe Clements Library is offering Open Hours Monday through Friday, from 12:00 pm \u2013 4:30 pm. To attend a behind the scenes guided tour of the Library and the exhibit, please see the schedule at myumi.ch\/Aw9Zb.\r\n \r\nCurated By: Dr. Ittai Orr and the Students of English 420, Winter 2022, with Maggie Vanderford and Julie Fremuth at the Clements Library.",
        "occurrence_notes":"Please enter through our North Entrance (glass vestibule) that faces the Hatcher Graduate Library tower to check-in.",
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