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        "description":"Join us for our in person hiring event on Monday, May 8, 2023, from 8-10am or 4-6pm. We are looking for RNs, LPNs and Support Staff.Nursing graduates and nursing students are welcome. We have opening in several areas. Come and learn about our culture and opportunities. For more information email Anne Brechenser, BSN, RN at brechensera@sjrmc.com.\n\nWe look forward to seeing you!!",
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        "location_name":"5215 Holy Cross Parkway, Mishawaka, Indiana 46545, United States",
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    {
        "datetime_modified":"20230224T145838",
        "datetime_start":"20230508T090000",
        "datetime_end":"20230508T200000",
        "has_end_time":1,
        "date_start":"2023-05-08",
        "date_end":"2023-05-08",
        "time_start":"09:00:00",
        "time_end":"20:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Early Astronomy in the University of Michigan Collections",
        "occurrence_title":"",
        "combined_title":"Early Astronomy in the University of Michigan Collections",
        "event_subtitle":"",
        "event_type":"Exhibition",
        "event_type_id":"7",
        "description":"Trace how astronomy was developed, studied, and disseminated through the centuries, from 1500 BCE to the Renaissance. On display is material drawn from the University of Michigan collections dealing with the history of early astronomy: manuscripts, early printed books, and artifacts illustrating Mesopotamian, Greek, Islamic, and Western European astronomy.\r\n\r\nThis exhibit and its permanent online counterpart (https:\/\/umlib.us\/earlyastronomy) are part of the Aratus Project, which was sponsored by the National Science Foundation and led by Prof. Francesca Schironi. The core of the project has been to study Aratus\u2019 \"Phaenomena,\" the most important poem on stars and constellations of the Graeco-Roman ancient world, and its exegetical tradition. Read an annotated edition and English translation of \"Phaenomena\" and its commentaries (https:\/\/aratus.classics.lsa.umich.edu\/). The physical and online exhibits place this research work within its later intellectual and historical context.\r\n\r\nCurated by: John Steele, Professor of the History of the Exact Sciences in Antiquity, Department of Egyptology and Assyriology, Brown University; Francesca Schironi, U-M Professor of Classical Studies; Evyn Kropf, U-M Librarian for Middle Eastern & North African Studies; Pablo Alvarez, U-M Curator (Special Collections Research Center).\r\n\r\nCheck Hatcher Gallery Exhibit Room hours: https:\/\/myumi.ch\/2mx44",
        "occurrence_notes":null,
                "guid":"101826-21811831@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/101826",
        "building_id":"1000181",
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        "room":"Hatcher Gallery Exhibit Room",
        "location_name":"Hatcher Graduate Library",
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    {
        "datetime_modified":"20230112T102807",
        "datetime_start":"20230508T090000",
        "datetime_end":"20230508T160000",
        "has_end_time":1,
        "date_start":"2023-05-08",
        "date_end":"2023-05-08",
        "time_start":"09:00:00",
        "time_end":"16:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Portraits of Feminism in Japan",
        "occurrence_title":"",
        "combined_title":"Portraits of Feminism in Japan: Winter 2023 Lane Hall Exhibit",
        "event_subtitle":"Winter 2023 Lane Hall Exhibit",
        "event_type":"Exhibition",
        "event_type_id":"7",
        "description":"What is feminism in Japan? Rather than imagining it as a singular, coherent object, this exhibit seeks to introduce the diversity, difference, and complexity inherent in feminist activism in Japan. As in other cultural contexts, \u201cfeminism\u201d in Japan can invoke sharply different associations, from office workers trying to reshape taken-for-granted structures of power and authority, to mothers advocating for safer school lunches after the 2011 Fukushima nuclear disasters, and queer couples seeking legal recognition for the families they have created. Mainstream feminist activism in Japan has focused on advocating for change in families, workplaces, schools, political institutions, and laws, among many other contexts. Many \u00ad\u2013 but certainly not all \u2013 feminist activists in Japan are also responding to the lasting legacies of Japanese colonial projects, working toward recognition, repair, and meaningful reparations for racial and gender-based violence that continue to impact communities disproportionately.\r\n\r\nThis exhibit features original portraits of feminists who have shaped the landscape of women's and gender rights in Japan and beyond. Created by nine contemporary artists in Japan and the United States, the portraits and accompanying texts challenge simplistic understandings of \"feminism\" while also drawing attention to a diversity of experiences, needs, and activism within Japan. This exhibit also spotlights the history of Japanese studies at the University of Michigan in conjunction with the Center for Japanese Studies' 75th anniversary celebration. \r\n\r\n\u201cPortraits of Feminism in Japan\u201d is open for viewing M-F 9am-4pm or by appointment. University of Michigan instructors can email LaneHallExhibits@umich.edu to request a group tour or schedule a class visit.\r\n\r\nFeatured artists:\r\nElaine Cromie, JenClare B. Gawaran, Takatoshi Hayashi, ivokuma (\u3044\u307c\u304f\u307e), Nami Kaneko (\u91d1\u5b50\u5948\u7f8e), Kang Jungsook, Lisa Taka Miyagi, Nancy Nishihira (\u897f\u5e73\u30fb\u30ca\u30f3\u30b7\u30fc), and Shigeki Shibata (\u67f4\u7530\u6ecb\u7d00)\r\n\r\nCuration team: \r\nAllison Alexy,  Bradly Hammond, Grace Mahoney, and Alexandria Molinari",
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        "tags":["Art","Asia","Exhibition","Japanese Studies","Visual Arts","Women's Studies"],
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        "datetime_modified":"20230426T152604",
        "datetime_start":"20230508T090000",
        "datetime_end":"20230508T164000",
        "has_end_time":1,
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        "date_end":"2023-05-08",
        "time_start":"09:00:00",
        "time_end":"16:40:00",
        "time_zone":"America\/Detroit",
        "event_title":"Saltiel Life Sciences Symposium 2023",
        "occurrence_title":"",
        "combined_title":"Saltiel Life Sciences Symposium 2023: Aging and Age-Related Diseases",
        "event_subtitle":"Aging and Age-Related Diseases",
        "event_type":"Workshop \/ Seminar",
        "event_type_id":"21",
        "description":"Aging is a universal phenomenon across all organisms. This year's Saltiel Life Sciences Symposium will explore the aging process and age-related disease models in a variety of model organisms, as well as the insights they can offer about human health and disease.\r\n\r\n*Schedule*\r\n\r\n9:00 a.m. | Welcome\r\nRoger D. Cone, Ph.D.\r\nVice Provost and Director, U-M Biosciences Initiative; Mary Sue Coleman Director, Life Sciences Institute; Professor of Molecular and Integrative Physiology, Medical School; Professor of Molecular, Cellular, and Developmental Biology, College of Literature, Science, and the Arts\r\n\r\n9:05 a.m. | The peculiar findings that link mitochondria to aging\r\nAndrew Dillin, Ph.D.\r\nThomas and Stacey Siebel Distinguished Chair in Stem Cell Biology, Professor of Immunology and Molecular Medicine, University of California, Berkeley; Investigator, Howard Hughes Medical Institute\r\n\r\n10:10 a.m. | Bennett J. Cohen Award for Research in Aging Lecture \u2014 The nutrient-sensing network and health during aging\r\nLinda Partridge, D.Phil.\r\nProfessorial Research Fellow, Honorary Weldon Professor of Biometry, Institute of Healthy Ageing and Department of Genetics, Evolution and Environment, University College London\r\n\r\n11:00 a.m. | Morning break\r\n\r\n11:10 a.m. | Aging and rejuvenation in ants\r\nClaude Desplan, Ph.D.\r\nSilver Professor of Biology and Neuroscience, New York University\r\n\r\n12:05 p.m. | Poster session and lunch, BSRB ABC and Upper Atrium\r\n\r\n1:30 p.m. | Welcome back\r\n\r\n1:35 p.m. | Introduction of the Mary Sue and Kenneth Coleman Life Sciences Lecturer\r\n\r\n1:45 p.m. | Mary Sue and Kenneth Coleman Life Sciences Lecture \u2014 Cross-species genetics to map new players in mitochondria and aging\r\nJohan Auwerx, M.D., Ph.D.\r\nProfessor, Laboratory of Integrative Systems Physiology, \u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, Switzerland\r\n\r\n2:35  p.m. | A blueprint for successful aging: The long-lived cancer-resistant naked mole-rat\r\nRochelle Buffenstein, Ph.D.\r\nResearch Professor, University of Illinois at Chicago\r\n\r\n3:30 p.m. | Afternoon break\r\n\r\n3:40 p.m. | How to die young at a very old age\r\nNir Barzilai, M.D.\r\nDirector, Einstein Institute for Aging Research; Professor of Medicine and Genetics, Albert Einstein College of Medicine\r\n\r\n4:35 p.m. | Closing remarks",
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        "building_name":"Taubman Biomedical Science Research Building",
        "campus_maps_id":"509",
        "room":"Kahn Auditorium",
        "location_name":"Taubman Biomedical Science Research Building",
        "has_livestream":0,
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        "tags":["Basic Science","Biology","biomedical research","Biosciences","Life Science","life sciences","life sciences institute","Research","science"],
        "website":"https:\/\/www.lsi.umich.edu\/events\/2023-05\/saltiel-life-sciences-symposiu",
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        "datetime_modified":"20230427T104617",
        "datetime_start":"20230508T093000",
        "datetime_end":"20230508T113000",
        "has_end_time":1,
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        "date_end":"2023-05-08",
        "time_start":"09:30:00",
        "time_end":"11:30:00",
        "time_zone":"America\/Detroit",
        "event_title":"Distributed Decision-making in Disrupted Industrial Environments Using a Multi-agent Framework",
        "occurrence_title":"",
        "combined_title":"Distributed Decision-making in Disrupted Industrial Environments Using a Multi-agent Framework: PhD Defense, Mingjie Bi",
        "event_subtitle":"PhD Defense, Mingjie Bi",
        "event_type":"Presentation",
        "event_type_id":"16",
        "description":"The modern industrial environment is becoming more complex and dynamic, due to customized and shifting market demands, highly connected businesses, and frequently upgraded technologies. In such environments, varying uncertainties and disruptions could occur and highly impact the performance of the manufacturing factories and supply chain networks. Conventional centralized decision-making approaches handle disruptions by re-optimizing across the entire system regardless of disruption type and scale, which require significant computational efforts, especially for complex and large-scale systems. Therefore, to stay competitive, industry enterprises need to develop a dynamic and flexible decision-making method that enables an agile and resilient response to these unexpected disruptions in industrial environments.\r\n\r\nEnabled by current Artificial Intelligence (AI) techniques, multi-agent control has been proposed to conduct distributed decision-making to provide an agile response to disruptions. A multi-agent system consists of various autonomous agents, which are cyber representations of their associated physical objects and have their own knowledge and goals. Agents communicate and interact with each other to make high-level decisions for their associated physical objects. In different industrial environments, agents could represent different system entities, such as the products and machines in manufacturing systems, or suppliers and customers in supply chains. However, most existing industrial multi-agent systems require prior knowledge of disruptions and predetermined rules and strategies to generate responses, which makes it difficult to handle unexpected disruptions. \r\n\r\nAiming to improve the agility and resiliency of industrial systems, this dissertation develops a model-based multi-agent framework to address risk management within an agile and resilient response to various unexpected industrial disruptions. The proposed multi-agent framework comprises model-based agents, heuristic-based communication, and optimization-based decision-making. The model-based agent architecture enables agents to update their knowledge and local environments dynamically. When agents need to make decisions, they utilize their knowledge as heuristics to instruct their communication strategies. Then based on their knowledge and communication information, agents can identify new actions by solving risk-aware optimizations to respond to unexpected disruptions dynamically. The proposed framework is tested in a simulated manufacturing environment and a supply chain instance, showcasing the improved flexibility, agility, and resiliency of the industrial systems. \r\n\r\nTo conclude, this dissertation pushes the fields of distributed decision-making for industrial systems closer to satisfying the requirements of modern industry: flexibility, agility, and resiliency, especially for manufacturing systems and supply chain networks. Enterprises could apply this framework to compute a resilient recovery plan to address a disruption quickly to minimize the negative effects. In addition, this dissertation contributes to standardizing the design of system-level decision-making using a multi-agent framework. The proposed methodology to design a multi-agent framework is transferable to other complex systems, such as multi-robot systems and autonomous vehicle teams, that consist of multiple intelligent entities.\r\n\r\nZoom: https:\/\/umich.zoom.us\/j\/94248906200, Passcode: mingjie",
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    {
        "datetime_modified":"20230313T150909",
        "datetime_start":"20230508T100000",
        "datetime_end":"20230508T170000",
        "has_end_time":1,
        "date_start":"2023-05-08",
        "date_end":"2023-05-08",
        "time_start":"10:00:00",
        "time_end":"17:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Openings: Title Pages in the History of Printed Books",
        "occurrence_title":"",
        "combined_title":"Openings: Title Pages in the History of Printed Books",
        "event_subtitle":"",
        "event_type":"Exhibition",
        "event_type_id":"7",
        "description":"This exhibit explores the creativity and utility of an essential part of practically every modern book, the title page. Such pages signal and inform, incite pleasure and intrigue, as well as conceal and mislead. The works shown here from the holdings of the University of Michigan Library illuminate critical moments in the history of books. Students in a Fall 2022 History Lab class researched and created the exhibit.\r\n\r\nThe exhibit is available for viewing in the Special Collections Research Center\u00a0(on the sixth floor of the Hatcher Library), Monday-Friday, 10am-4:30pm.",
        "occurrence_notes":null,
                "guid":"104490-21809423@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/104490",
        "building_id":"1000181",
        "building_name":"Hatcher Graduate Library",
        "campus_maps_id":"65",
        "room":"Special Collections Exhibit Space (6th floor)",
        "location_name":"Hatcher Graduate Library",
        "has_livestream":0,
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        "tags":["Art","Books","Free","History","Library"],
        "website":"",
        "sponsors":[
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                "group_id":"1186",
                "website":"https:\/\/www.facebook.com\/UMichLibrary\/"                }                    ],
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        "datetime_modified":"20230601T141842",
        "datetime_start":"20230508T100000",
        "datetime_end":"20230508T170000",
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        "date_end":"2023-05-08",
        "time_start":"10:00:00",
        "time_end":"17:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"UN\/EARTH",
        "occurrence_title":"",
        "combined_title":"UN\/EARTH: Featured Exhibit: UN\/EARTH",
        "event_subtitle":"Featured Exhibit: UN\/EARTH",
        "event_type":"Exhibition",
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        "description":"Featuring work by Gina Gibson, UN\/EARTH explores science and art from a mile underground. Located in the former Homestake gold mine in Lead, South Dakota, the Sanford Underground Research Facility (SURF) houses experiments that give us a better understanding of the universe. The location\u2014deep underground\u2014provides a near-perfect environment for experiments that need to escape the constant bombardment of cosmic radiation, which can interfere with the detection of rare physics events. Built in collaboration with the University of Michigan, the LUX-Zeplin is the world\u2019s most sensitive dark matter experiment. SURF also hosts experiments in biology, geology and engineering.\r\n\r\nGina Gibson is an internationally exhibiting artist and professor of Graphic Design at Black Hills State University. In 2019, Gibson became the first artist in residence at the Sanford Underground Research Facility. Gibson's work celebrates the search deep below the surface for beauty in the old and new, the light and dark, and the known and unknown.\r\n\r\nUN\/EARTH was developed in collaboration with the U-M Department of Physics, the Sanford Underground Research Facility and Black Hills State University.",
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        "tags":["Art","Culture","Exhibition","Free","Museum","Natural Sciences","Science","Visual Arts"],
        "website":"https:\/\/www.bhsu.edu\/directory\/Faculty-and-Staff\/Gibson_Gina",
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        "datetime_modified":"20230523T063042",
        "datetime_start":"20230508T110000",
        "datetime_end":"20230508T120000",
        "has_end_time":1,
        "date_start":"2023-05-08",
        "date_end":"2023-05-08",
        "time_start":"11:00:00",
        "time_end":"12:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"True Life: \"I Want to Be a Teacher\" Webinar | Baltimore City Public Schools",
        "occurrence_title":"",
        "combined_title":"True Life: \"I Want to Be a Teacher\" Webinar | Baltimore City Public Schools",
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        "event_type_id":"2",
        "description":"Hello, everyone -\n\nBaltimore City Public Schools (BCPS) welcomes you to another bi-weekly episode of \"True Life: I Want to Be a Teacher.\" In this webinar, we aim to introduce you to our school district, toour goals and the blueprint by which we intend to achieve them, and to some of the benefits of working at BCPS.\n\nWe welcome teachers and prospective teachers of all backgrounds and experience levels. If you think you might want to be a teacher in Charm City (Baltimore), tune in and take advantage of our recruitment team's time and knowledge - we're here to help.\n\nThanks for checking us out!\n\nBaltimore City Public Schools' Recruitment Team\n\n________________________________________________________________________________\nMicrosoft Teams meeting\nJoin on your computer, mobileapp or room device\nClick here to join the meeting\nMeeting ID: 249 619 340 299 \nPasscode: fUBe3C \nDownload Teams |  Join on the web\nOr call in (audio only)\n+1 443-961-1488,,896852536# \u00a0 United States, Baltimore \nPhone Conference ID: 896 852 536# \nFind a local number |  Reset PIN\nLearn More |  Meeting options",
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                "group_id":"1140",
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        "datetime_modified":"20230427T121417",
        "datetime_start":"20230508T120000",
        "datetime_end":"20230508T160000",
        "has_end_time":1,
        "date_start":"2023-05-08",
        "date_end":"2023-05-08",
        "time_start":"12:00:00",
        "time_end":"16:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Building on a Century of Collecting at the Clements Library",
        "occurrence_title":"",
        "combined_title":"Building on a Century of Collecting at the Clements Library",
        "event_subtitle":"",
        "event_type":"Tours",
        "event_type_id":"25",
        "description":"As we celebrate the library\u2019s centennial, this exhibit is an attempt to answer a question asked often by visitors, how do you decide what to acquire to add to your collections.\r\n\r\nIt builds on the landmark publication of the library\u2019s 75th anniversary, One Hundred and One Treasures From the Collections of the William L. Clements Library, edited by former library director John Dann. This exhibit\u2014and its expanded online version\u2014pairs items from 101 Treasures with related items that have for the most part been acquired since 1998. Those that were acquired earlier are items about which we\u2019ve learned new things in the intervening 25 years.",
        "occurrence_notes":null,
                "guid":"107840-21817524@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/107840",
        "building_id":"1000159",
        "building_name":"William Clements Library",
        "campus_maps_id":"165",
        "room":"",
        "location_name":"William Clements Library",
        "has_livestream":0,
        "cost":"",
        "tags":["american culture","american history","Centennial","Exhibition","Free","history","In Person","libraries","Library","Tour"],
        "website":"https:\/\/clements.umich.edu\/",
        "sponsors":[
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                "group_id":"1727",
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        "datetime_modified":"20230112T102807",
        "datetime_start":"20230508T120000",
        "datetime_end":"20230508T130000",
        "has_end_time":1,
        "date_start":"2023-05-08",
        "date_end":"2023-05-08",
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        "time_end":"13:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Portraits of Feminism in Japan",
        "occurrence_title":"",
        "combined_title":"Portraits of Feminism in Japan: Winter 2023 Lane Hall Exhibit",
        "event_subtitle":"Winter 2023 Lane Hall Exhibit",
        "event_type":"Exhibition",
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        "description":"What is feminism in Japan? Rather than imagining it as a singular, coherent object, this exhibit seeks to introduce the diversity, difference, and complexity inherent in feminist activism in Japan. As in other cultural contexts, \u201cfeminism\u201d in Japan can invoke sharply different associations, from office workers trying to reshape taken-for-granted structures of power and authority, to mothers advocating for safer school lunches after the 2011 Fukushima nuclear disasters, and queer couples seeking legal recognition for the families they have created. Mainstream feminist activism in Japan has focused on advocating for change in families, workplaces, schools, political institutions, and laws, among many other contexts. Many \u00ad\u2013 but certainly not all \u2013 feminist activists in Japan are also responding to the lasting legacies of Japanese colonial projects, working toward recognition, repair, and meaningful reparations for racial and gender-based violence that continue to impact communities disproportionately.\r\n\r\nThis exhibit features original portraits of feminists who have shaped the landscape of women's and gender rights in Japan and beyond. Created by nine contemporary artists in Japan and the United States, the portraits and accompanying texts challenge simplistic understandings of \"feminism\" while also drawing attention to a diversity of experiences, needs, and activism within Japan. This exhibit also spotlights the history of Japanese studies at the University of Michigan in conjunction with the Center for Japanese Studies' 75th anniversary celebration. \r\n\r\n\u201cPortraits of Feminism in Japan\u201d is open for viewing M-F 9am-4pm or by appointment. University of Michigan instructors can email LaneHallExhibits@umich.edu to request a group tour or schedule a class visit.\r\n\r\nFeatured artists:\r\nElaine Cromie, JenClare B. Gawaran, Takatoshi Hayashi, ivokuma (\u3044\u307c\u304f\u307e), Nami Kaneko (\u91d1\u5b50\u5948\u7f8e), Kang Jungsook, Lisa Taka Miyagi, Nancy Nishihira (\u897f\u5e73\u30fb\u30ca\u30f3\u30b7\u30fc), and Shigeki Shibata (\u67f4\u7530\u6ecb\u7d00)\r\n\r\nCuration team: \r\nAllison Alexy,  Bradly Hammond, Grace Mahoney, and Alexandria Molinari",
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        "tags":["Art","Asia","Exhibition","Japanese Studies","Visual Arts","Women's Studies"],
        "website":"https:\/\/twitter.com\/UMichIRWG",
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                "group_id":"1031",
                "website":"http:\/\/irwg.umich.edu\/"                },             {
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        "datetime_modified":"20230426T121551",
        "datetime_start":"20230508T140000",
        "datetime_end":"20230508T153000",
        "has_end_time":1,
        "date_start":"2023-05-08",
        "date_end":"2023-05-08",
        "time_start":"14:00:00",
        "time_end":"15:30:00",
        "time_zone":"America\/Detroit",
        "event_title":"Zoe Kai Wai Lei, organ",
        "occurrence_title":"",
        "combined_title":"Zoe Kai Wai Lei, organ",
        "event_subtitle":"",
        "event_type":"Performance",
        "event_type_id":"15",
        "description":"Graduate student Zoe Kai Wai Lei performs.",
        "occurrence_notes":null,
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    {
        "datetime_modified":"20230323T134339",
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        "date_end":"2023-05-08",
        "time_start":"16:00:00",
        "time_end":"17:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"PROFESSOR NILS WALTER, THE FRANCIS S. COLLINS COLLEGIATE PROFESSORSHIP IN CHEMISTRY, BIOPHYSICS AND BIOLOGICAL CHEMISTRY, INAUGURAL LECTURE",
        "occurrence_title":"",
        "combined_title":"PROFESSOR NILS WALTER, THE FRANCIS S. COLLINS COLLEGIATE PROFESSORSHIP IN CHEMISTRY, BIOPHYSICS AND BIOLOGICAL CHEMISTRY, INAUGURAL LECTURE: Can RNA Do It All?  From Spawning Life on Earth to Fueling Modern Personalized Medicine  (Read: mRNA Vaccines)",
        "event_subtitle":"Can RNA Do It All?  From Spawning Life on Earth to Fueling Modern Personalized Medicine  (Read: mRNA Vaccines)",
        "event_type":"Lecture \/ Discussion",
        "event_type_id":"13",
        "description":"Billions of safely given mRNA vaccine doses have saved millions of lives worldwide and proved beyond the shadow of a doubt that a transformative era of RNA Therapeutics is upon us, with great promise for overcoming virtually all diseases within this century through personalized medicines.  Yet RNA can do so much more!  Since the human genome project was completed, we know that at least 75% of our 3 billion DNA base pairs are transcribed into RNA, with the vast majority not coding for proteins but rather for \u201cnon-coding\u201d RNAs (ncRNAs).  Many of these ncRNAs remain uncharacterized in terms of their structure and function, spawning discussions of whether they are functional or not (and what \u201cbiological function\u201d even is!).  These applications and discoveries suggest that so far we have underestimated the far-reaching \u201cRNA World\u201d in our body, which may well also have spawned life on earth.  \r\nAfter an introduction to the power and benefits of these \u201cnew\u201d and \u201cold\u201d RNA Worlds, this seminar will highlight some of the foundational work by the Walter lab, in which we use modern single molecule fluorescence microscopy to dissect and control the nanometer-sized RNA-protein assemblies that govern life, and particularly gene expression.  Specifically, single molecule fluorescence resonance energy transfer (smFRET) allows us to measure distances at the 2-8 nm scale, whereas complementary super-resolution localization techniques measure distances in the 10 nm and longer range where biology occurs.  Embracing the power of these technical advances, we have combined single-molecule, biochemical and computational simulation approaches to show that a bacterial riboswitch \u2013 controlled by a metabolite ligand \u2013 manipulates the speed of the much larger bacterial RNA polymerase.  We posit that many more examples of such intimate coupling between RNA folding and gene expression remain to be discovered, leading to opportunities to identify new Achilles\u2019 heels of the many pathogens that threaten human health.  In addition, we are developing tools to observe single RNA nanomachines in action within their natural habitats inside living cells, leading to discoveries that may guide the development of novel cancer-fighting approaches.\r\n\r\n\r\nIf you are unable to attend this lecture in person please see below.\r\n\r\nPlease click the link below to join the webinar:\r\nhttps:\/\/umich.zoom.us\/j\/94011983924\r\nOr One tap mobile : \r\n    US: +16468769923,,94011983924#  or +16469313860,,94011983924# \r\nOr Telephone:\r\n    Dial(for higher quality, dial a number based on your current location):\r\n        US: +1 646 876 9923  or +1 646 931 3860  or +1 301 715 8592  or +1 305 224 1968  or +1 309 205 3325  or +1 312 626 6799  or +1 719 359 4580  or +1 253 205 0468  or +1 253 215 8782  or +1 346 248 7799  or +1 360 209 5623  or +1 386 347 5053  or +1 507 473 4847  or +1 564 217 2000  or +1 669 444 9171  or +1 669 900 6833  or +1 689 278 1000 \r\n        Canada: +1 587 328 1099  or +1 647 374 4685  or +1 647 558 0588  or +1 778 907 2071  or +1 780 666 0144  or +1 204 272 7920  or +1 438 809 7799 \r\nWebinar ID: 940 1198 3924\r\n    International numbers available: https:\/\/umich.zoom.us\/u\/adhOU6qjZP\r\n\r\nOr an H.323\/SIP room system:\r\n    H.323: \r\n    162.255.37.11 (US West)\r\n    162.255.36.11 (US East)\r\n    115.114.131.7 (India Mumbai)\r\n    115.114.115.7 (India Hyderabad)\r\n    213.19.144.110 (Amsterdam Netherlands)\r\n    213.244.140.110 (Germany)\r\n    103.122.166.55 (Australia Sydney)\r\n    103.122.167.55 (Australia Melbourne)\r\n    149.137.40.110 (Singapore)\r\n    64.211.144.160 (Brazil)\r\n    149.137.68.253 (Mexico)\r\n    69.174.57.160 (Canada Toronto)\r\n    65.39.152.160 (Canada Vancouver)\r\n    207.226.132.110 (Japan Tokyo)\r\n    149.137.24.110 (Japan Osaka)\r\n    Meeting ID: 940 1198 3924\r\n    SIP: 94011983924@zoomcrc.com",
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        "description":"New music!\r\n\r\nWhen songwriter Zach Williams met guitarist and fellow Southerner Brian Elmquist and vocalist Kanene Donehey Pipkin at Dizzy's Diner in Brooklyn for breakfast one morning in 2010, the trio decided to jam. \"Three songs in,\" Williams recalls, \"I decided I should quit what I'm going and just make music with these people.\" The trio's music is exuberant in its playing, welcoming in its attitude. Though the lyrics have a melancholic undercurrent, the tracks are more often rave-ups than ruminations, with swelling three-part harmonies and rousing group-sung choruses;The name \"The Lone Bellow\" refers to a lonely bull Zach Williams heard on a childhood family trip. Indeed, there is a strong familial feel to The Lone Bellow, a recurring theme of inclusiveness. The Lone Bellow comes to The Ark with a new album, \u201cLove Songs for Losers.\u201d\r\n\r\n\r\nPlease visit https:\/\/mutotix.umich.edu\/3961\/3962 for more detail.",
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