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        "event_title":"The People\u2019s Bicentennial",
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        "combined_title":"The People\u2019s Bicentennial",
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        "description":"This selection of original artifacts documents the work of the Peoples Bicentennial Commission (PBC), which challenged the official, corporate-sponsored commemoration of the 1976 bicentennial. This year we celebrate the 250th anniversary of the signing of the Declaration of Independence.\n\nItems on display are from the Joseph A. Labadie Collection, which documents social protest movements and radical history.\n\nHOURS\nSunday 2-8pm\nMonday-Thursday 9am-8pm\nFriday 9am-4pm\nSaturday 11am-5pm",
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        "room":"Hatcher Gallery Exhibit Room (1st floor)",
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        "tags":["Library","History","Free"],
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        "datetime_modified":"20260107T120530",
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        "time_start":"11:00:00",
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        "event_title":"Human Genetics Research Seminar Series",
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        "combined_title":"Human Genetics Research Seminar Series: presenting Yang Shi, PhD Professor of Epigenetics Ludwig Institute for Cancer Research, Oxford University, Oxford, England",
        "event_subtitle":"presenting Yang Shi, PhD Professor of Epigenetics Ludwig Institute for Cancer Research, Oxford University, Oxford, England",
        "event_type":"Lecture \/ Discussion",
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        "description":"Monday, September 14, 2026\r\n11:00am - 12:00pm\r\nLocation TBD\r\n\r\nYang Shi, PhD\r\nProfessor of Epigenetics\r\nLudwig Institute for Cancer Research\r\nOxford University, Oxford, England\r\n\u201cSeminar Title TBD\u201d\r\n\r\nHosted By: Shigeki Iwase, PhD, Department of Human Genetics\r\n___\r\nBefore joining Ludwig Oxford in 2020, I was Professor of Cell Biology and C. H. Waddington Professor of Pediatrics at Harvard Medical School. I received my PhD from New York University and postdoctoral training at Princeton University. I joined Harvard Medical School as an Assistant Professor in 1991 and was appointed a Professor of Pathology in 2004. In 2009 I joined the Newborn Medicine Division of Boston Children\u2019s Hospital.\r\n\r\nI am interested in identifying key epigenetic regulators in cancer, elucidating their mechanism of action and providing the conceptual basis for translating our basic findings to the clinic via the development of new therapeutic strategies. With the discovery of the first histone methyl eraser, LSD1, in 2004, our group demonstrated that histone methylation is dynamically regulated, which overturned the long-held dogma that such modifications were static and irreversible. We have also discovered many additional histone demethylases with different specificities, and novel readers, including those that specifically recognize unmodified lysine and arginine and suggest that the unmodified states are not simply a ground neutral state of epigenetic information but rather likely code for epigenetic information as modified states. Importantly, many of these chromatin enzymes and readers have since been implicated in various types of human cancers, indicating an important role of chromatin regulation in tumorigenesis.\r\n\r\nMore recently, we have also been studying RNA modifications and how they impact gene expression regulation. In many ways this exciting field parallels the early days of chromatin biochemistry and biology, i.e., the nature and the biological and pathological functions of RNA modifications, as well as the enzymes responsible for writing, erasing and reading them, are just beginning to be understood.\r\n\r\nAt Ludwig Oxford, my lab is focusing on two questions. First, how to convert \u201ccold tumors to \u201chot\u201d and how to sustain durable responses to cancer immune checkpoint blockade therapy. Second, how to induce therapeutic differentiation of cancers, using acute myeloid leukemia and diffuse intrinsic pontine glioma as models where chromatin\/epigenetics have been shown to play a crucial role in the maintenance of a poorly differentiated state.",
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        "tags":["Reception","lecture","Life Science","lifton","Medicine","Natural Sciences","neel","neurological disease","Postdoctoral Research Fellows","Public Health","Public Policy","basic sciences","research","Science","seminar","sodium channel","symposium","Basic Science","Human Genetics, Genetics, Neurogenetic Diseases","Information and Technology","biolgical chemistry","biological chemistry","biological science","Biology","Biosciences","Bsbsigns","cancer","Chemistry","epilepsy","Faculty","Free","genetics","genome","genomics","human genetics","Human Genetics, Genetics, Epidemiology","Discussion"],
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        "datetime_start":"20260914T153000",
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        "date_start":"2026-09-14",
        "date_end":"2026-09-14",
        "time_start":"15:30:00",
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        "time_zone":"America\/Detroit",
        "event_title":"RCGD Fall Seminar Series: Global Perspectives on  Culture & Health (Miguel Arce Renter\u00eda)",
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        "combined_title":"RCGD Fall Seminar Series: Global Perspectives on  Culture & Health (Miguel Arce Renter\u00eda)",
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        "description":"RCGD Fall 2026 Seminar Series: Global Perspectives on Culture & Health, meets Mondays 3:30 to 5 at ISR Thompson 1430.\n\nGlobal Perspectives on Culture and Health explores fundamental aspects of human life.  Culture facilitates human interaction by providing meaning to lived experience. Accounting for culture in both theories and methods potentially advances the study of health by connecting the macro and micro levels of human experience. Yet, culture should be understood as dynamic and complex. It fundamentally shapes individuals and simultaneously is shaped by individuals.  The importance of systematically attending to culture includes topics of values, language, immigration, and society.\n\nTheories and methods that incorporate culture hold great potential for advancing the understanding of health outcomes and health trajectories in various global contexts.\n\nThe speakers for this series will focus on various aspects of culture and diverse groups living in the U.S. and across the globe to address the ways in which attending to culture helps clarify and overcome challenges to good health.\n\nThe Group Dynamics Seminar series is considered one of the longest running seminar series in the social sciences. It has been running uninterruptedly since it was founded by Kurt Lewin in the 1920\u2019s in Berlin. The seminar series runs every semester on a theme chosen by faculty organizer\/s who are affiliated with the Research Center for Group Dynamics at the Institute for Social Research. A very important feature of this seminar today is its interdisciplinary nature. Recent themes have included political polarization, evolution and human behavior, and cultural psychology.\n\nThese events are held Mondays from 3:30 to 5.\nIn person: ISR Thompson 1430, unless otherwise specified.\nOrganized by Kristine Ajrouch and Sela Panapasa\nEvents are not recorded, but as permissions allow, interviews with speakers are later posted to our YouTube playlist.",
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        "event_title":"Margaret Glaspy",
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