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DTSTAMP:20260903T082527
DTSTART;TZID=America/Detroit:20260917T150000
DTEND;TZID=America/Detroit:20260917T160000
SUMMARY:Workshop / Seminar:Biomedical Engineering (BME 500) Seminar Series
DESCRIPTION:Mechanobiology and Synthetic Cells: Understanding and Engineering Adaptive Cellular Systems\n\nAbstract:\nBiological cells and synthetic cell-like systems both rely on dynamic membranes\, molecular organization\, and mechanical interactions with their surroundings to sense\, respond\, and adapt. In this seminar\, I will discuss our lab’s efforts to understand and engineer these behaviors across living and synthetic systems. The first part of the talk will focus on cellular mechanobiology\, with an emphasis on cellular unjamming in three-dimensional environments. While unjamming transitions have been widely studied in collective cell migration and tissue remodeling\, their regulation in 3D remains less understood. I will describe our work investigating how cells transition between solid-like and fluid-like collective behaviors in physiologically relevant environments\, and how these transitions are coupled to cell-generated forces\, matrix interactions\, and multicellular organization.\n\nThe second part of the talk will shift toward bottom-up synthetic biology and the construction of synthetic cells that can sense and respond to environmental cues. I will present our work developing pH-sensing synthetic cells\, designed to detect chemical changes in their surroundings and produce measurable biochemical or physical responses. I will also discuss our efforts to engineer desiccation-resistant synthetic cells\, motivated by the need to create robust cell-like systems that can survive extreme or fluctuating environmental conditions. Together\, these projects highlight how principles from cell mechanobiology\, membrane biophysics\, and synthetic biology can be integrated to understand the design rules of living systems and to build programmable\, resilient cellular mimics.     \nBio:\nAllen Liu received a B.Sc. with Honors in Biochemistry from the University of British Columbia in 2001 and a Ph.D. in Biophysics from the University of California\, Berkeley in 2007\, followed by postdoctoral training at The Scripps Research Institute in La Jolla. He established his research group in 2012 and is currently Professor of Mechanical Engineering\, Biomedical Engineering\, and Biophysics\, as well as Associate Chair for Graduate Education in Mechanical Engineering\, at the University of Michigan.\n\nHis research focuses on cellular mechanotransduction and bottom-up synthetic biology\, integrating approaches from quantitative cell biology\, synthetic biology\, biophysics\, and microfluidics. He has published more than 100 peer-reviewed papers and delivered more than 100 invited presentations. His honors include the NIH Director’s New Innovator Award\; recognition as a Young Innovator by Cellular and Molecular Bioengineering and as a Rising Star by the Biomedical Engineering Society\; and selection as a Future of Biophysics speaker at a Burroughs Wellcome Fund symposium at the Biophysical Society Meeting. He is an elected Fellow of the Biomedical Engineering Society\, a Fellow of the Royal Society of Chemistry\, and a recipient of the Endeavour Executive Fellowship in Australia and the Alexander von Humboldt Fellowship for Experienced Researchers in Germany.
UID:151467-21911628@events.umich.edu
URL:https://events.umich.edu/event/151467
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Research,Basic Science,Michigan Engineering,Medicine,engineering,engineer,bme,Biosciences,Biointerfaces,Biology,biomedical,biomedical engineering,Bioninterfaces,Biotechnology
LOCATION:Lurie Biomedical Engineering (formerly ATL) - 1130
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20260911T090229
DTSTART;TZID=America/Detroit:20260924T150000
DTEND;TZID=America/Detroit:20260924T160000
SUMMARY:Workshop / Seminar:Biomedical Engineering (BME 500) Seminar Series
DESCRIPTION:Immunodeficient Rabbit Models: A new platform for biomedical discovery\nAbstract:\nImmunodeficient rodent models have become essential to the advancement of many prominent biomedical fields\, including immuno-oncology\, regenerative medicine\, and human cell therapy development. While there are several commercially available immunodeficient mouse and rat models\, biomedical researchers still face insurmountable challenges that cannot be resolved due to the inherent limitations of their small body size and short lifespan\, which limit their utility in translational studies. These models include monogenic knockout lines\, such as Il2rg\, Rag1 or 2\, and Prkdc\, as well as multigenic knockout lines on a non-obesity diabetic background\, for example the popular NSG and NRG mice. Our lab has established multiple genetically engineered lines of immunodeficient New Zealand White rabbits\, using CRISPR/Cas9 technology\, including knockout models of critical immune system genes\, such as FOXN1\, RAG2\, and IL2RG. This talk will focus on the research and development needed to overcome obstacles in the housing and care for immunodeficient rabbit models as well as the characterization of the NZRG rabbit\, a new multigenic ultra-immunodeficient rabbit model.   \n\nBio:\nDr. Pallas is a veterinary scientist and clinical associate professor of laboratory animal medicine at the University of Michigan. His expertise lies in the development and use of genetically modified rabbit models for biomedical research. His research efforts are focused on the creation and characterization of genetically engineered lines of immunodeficient rabbits\, to provide the research community with a transformational non-rodent model for cancer research and regenerative medicine applications. He also serves as the Veterinary Director for the NIH funded National Center of Rabbit Models for Translational Research (NCRM). In these roles\, he leads in-vivo experimental studies and provides guidance and oversight in the clinical\, surgical\, and pathological related aspects of newly generated disease models.
UID:151997-21912590@events.umich.edu
URL:https://events.umich.edu/event/151997
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biology,Research,Pre Med,Michigan Engineering,Medicine,engineering,engineer,bme,Biotechnology,Biosciences,Bioninterfaces,biomedical engineering,Biointerfaces,Basic Science,biomedical
LOCATION:Lurie Biomedical Engineering (formerly ATL) - 1130
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20260916T101552
DTSTART;TZID=America/Detroit:20261001T150000
DTEND;TZID=America/Detroit:20261001T160000
SUMMARY:Workshop / Seminar:Biomedical Engineering (BME 500) Seminar Series
DESCRIPTION:Implementation Research for Brain-Computer Interface to Access Commercial Software\nAbstract:\nWearable brain-computer interfaces (BCIs) are a promising option to provide access to technology for those with severe disabilities without requiring physical movement. However\, BCIs are not yet available as a commercial assistive technology. Dr. Huggins' University of Michigan Direct Brain Interface Laboratory focuses on making BCIs practical for people who need them.  This involves identifying and solving usability issues that others have overlooked. Our BCI includes expanding capabilities to access commercial software and provides usability features designed for real-world\, user-paced communication. Our in-home clinical trials and laboratory testing of BCI with real-world tasks have identified additional challenges that must be overcome to expand BCI availability and usability so that BCI can become a standard of care for those with the most profound physical disabilities.     \n\nBio:\nDr. Huggins is trained in Computer Engineering and Biomedical Engineering with degrees from Carnegie Mellon and the University of Michigan in Ann Arbor. She completed a clinical Rehabilitation Engineering Internship. She co-founded the University of Michigan Direct Brain Interface Laboratory and has led it since 2007. Her current focus is making EEG-based brain-computer interfaces practical for people who need them. Outside the lab\, Dr. Huggins enjoys knitting\, birdwatching\, genealogy\, cooking for her husband\, and being Mom to her college-age children.\n\nDr. Huggins was a founding member of the board of directors of the Brain-Computer Interface Society. She has a patent on the BCI hold-release algorithm and BCI use for multiple choice tests.  Dr. Huggins’ research has received grant funding from the Cerebral Palsy Alliance Research Foundation\, the Mildred E. Swanson Foundation\, the National Institute on Disability\, Independent Living and Rehabilitation Research\, the National Science Foundation\, the National Institutes of Health\, the Prentke Romich Company\, and funding from General Motors.
UID:152255-21913442@events.umich.edu
URL:https://events.umich.edu/event/152255
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Michigan Engineering,Medicine,engineering,engineer,bme,Biotechnology,Biosciences,Bioninterfaces,biomedical engineering,biomedical,Biology,Biointerfaces,Basic Science
LOCATION:Lurie Biomedical Engineering (formerly ATL) - 1130
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20260911T090409
DTSTART;TZID=America/Detroit:20261002T130000
DTEND;TZID=America/Detroit:20261002T150000
SUMMARY:Reception / Open House:BME Open House: Explore Biomedical Engineering
DESCRIPTION:Curious about Biomedical Engineering? Stop by the BME Open House to explore our space\, meet faculty\, students and student organizations. Meet our advisors\, enjoy food\, casual conversations\, lab tours\, hands-on STEM activities\, and helpful information about the academic\, research\, and community available to BME students.\nRegister here: https://sessions.studentlife.umich.edu/track/event/session/111526
UID:151644-21911889@events.umich.edu
URL:https://events.umich.edu/event/151644
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biomedical Engineering,Engineering,In Person,North Campus,Pre-Health,Prospective Undergraduate Students,Tour,Undergraduate Students,Welcome to Michigan
LOCATION:Lurie Biomedical Engineering (formerly ATL) - LBME Atrium
CONTACT:
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