{ "150862-21910329": { "datetime_modified":"20260825T095216", "datetime_start":"20260903T150000", "datetime_end":"20260903T160000", "has_end_time":1, "date_start":"2026-09-03", "date_end":"2026-09-03", "time_start":"15:00:00", "time_end":"16:00:00", "time_zone":"America\/Detroit", "event_title":"Biomedical Engineering (BME 500) Seminar Series", "occurrence_title":"", "combined_title":"Biomedical Engineering (BME 500) Seminar Series: \"How Blood Gets to Where It's Needed: Mathematical Modeling of Cardiovascular Regulation,\" with Matthew Eden, Ph.D.", "event_subtitle":"\"How Blood Gets to Where It's Needed: Mathematical Modeling of Cardiovascular Regulation,\" with Matthew Eden, Ph.D.", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"How Blood Gets to Where It's Needed: Mathematical Modeling of Cardiovascular Regulation\nAbstract:\nOn a daily basis, we experience our cardiovascular system continuously adapting to our environment, whether it be due to exercise, stress, or standing up too quickly. Cardiovascular regulation is driven by complex control mechanisms acting in concert at both systemic (such as neurohormonal control) and organ levels (such as local autoregulation) to dynamically govern tissue perfusion. However, our understanding of cardiovascular regulation remains largely phenomenological due to the challenges associated with unraveling the systemic and local control mechanisms operating simultaneously across vastly different spatial and temporal scales. Our research group aims to provide a better quantitative understanding of cardiovascular regulation by leveraging state-of-the-art animal models to develop novel mathematical models. \n\nIn this seminar, I will first present our work on modeling dynamic cardiovascular adaptations during varying degrees of hemorrhage. We developed a closed-loop, lumped-parameter model to simulate both systemic and organ-specific control mechanisms that compensate for blood loss and redistribute blood flow towards vital organs (e.g., the brain). I will then discuss our efforts to develop a microstructurally motivated model of autoregulation in the coronary circulation, which integrates principles of coronary physiology into a vascular biomechanical framework. We show how a microstructurally motivated model can be used to investigate coronary circulation autoregulation in both health and disease. Collectively, this seminar will demonstrate how mathematical modeling deepens our understanding of cardiovascular physiology and pathophysiology, and how it can be leveraged to engineer next-generation treatment strategies.. \nBio:\nMatthew Eden is a Postdoctoral Research Fellow in the Computational Vascular Biomechanics Laboratory within the University of Michigan\u2019s Department of Surgery, Section of Vascular Surgery. His research focuses on developing multi-scale physiological models of cardiovascular hemodynamics and regulation, including coronary autoregulation and hemodynamic responses to hemorrhage. He earned his Ph.D. in Bioengineering from Northeastern University, where he leveraged experiments and computation to investigate the cardiopulmonary health consequences of inhaling wildfire smoke and e-cigarette aerosols. He holds B.S. degrees from the University of Massachusetts Amherst in mechanical engineering and applied mathematics.", "occurrence_notes":null, "guid":"150862-21910329@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/150862", "building_id":"1000406", "building_name":"Lurie Biomedical Engineering (formerly ATL)", "campus_maps_id":"7", "room":"1130", "location_name":"Lurie Biomedical Engineering (formerly ATL)", "has_livestream":0, "cost":"", "tags":["Michigan Engineering","Medicine","engineering","engineer","bme","Biotechnology","Biosciences","biomedical engineering","biomedical","Biology","Biointerfaces","Basic Science"], "website":"http:\/\/bme.umich.edu", "sponsors":[ { "group_name":"Biomedical Engineering", "group_id":"1143", "website":"https:\/\/www.facebook.com\/profile.php?id=100094127215673" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/08\/event_150862_original-1.jpg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2026\/08\/event_150862_original-1.jpg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/08\/event_150862_original-1.jpg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_2x\/media\/attachments\/2026\/08\/event_150862_original-1.jpg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2026\/08\/event_150862_original-1.jpg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2026\/08\/event_150862_original-1.jpg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2026\/08\/event_150862_original-1.jpg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2026\/08\/event_150862_original-1.jpg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large_lightbox\/media\/attachments\/2026\/08\/event_150862_original-1.jpg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2026\/08\/event_150862_original-1.jpg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2026\/08\/event_150862_original-1.jpg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2026\/08\/event_150862_original-1.jpg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2026\/08\/event_150862_original-1.jpg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2026\/08\/event_150862_original-1.jpg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_large\/media\/attachments\/2026\/08\/event_150862_original-1.jpg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_thumb\/media\/attachments\/2026\/08\/event_150862_original-1.jpg" }, "occurrence_count":1, "first_occurrence":21910329 } , "149535-21906578": { "datetime_modified":"20260723T091503", "datetime_start":"20261002T130000", "datetime_end":"20261002T150000", "has_end_time":1, "date_start":"2026-10-02", "date_end":"2026-10-02", "time_start":"13:00:00", "time_end":"15:00:00", "time_zone":"America\/Detroit", "event_title":"Biomedical Engineering Open House", "occurrence_title":"", "combined_title":"Biomedical Engineering Open House: Welcoming Undeclared Engineering Students and Those Interested in BME", "event_subtitle":"Welcoming Undeclared Engineering Students and Those Interested in BME", "event_type":"Other", "event_type_id":"22", "description":"The BME Open House is designed to introduce undeclared first-year engineering students to the Biomedical Engineering community, academic pathways, research areas, student organizations, faculty, staff, and student resources. The event will provide an informal and welcoming opportunity for students to explore BME spaces, meet faculty and advisors, learn about student organizations, understand the process for declaring BME, and to learn about BME career pathways. The event will emphasize discovery and connection rather than formal advising or immediate declaration. Students will leave with a clearer understanding of what BME offers, how to continue exploring the major, and what resources are available for declared BME students.\n\nThe BME Open House will feature several interactive stations designed to help first-year Engineering students explore the department, connect with the community, and learn about opportunities in Biomedical Engineering. Student organization tables will introduce students to ways to get involved, a tour sign-up area will lead short LBME\/lab tours. A Student Services Corner will provide informal guidance on advising, the BME declaration process, as well as BME career pathways. Faculty\/student roundtables will offer casual conversations about research, courses, and design, supported by conversation prompts (\"Ask Me About\"). The event will also include a hands-on STEM activity table and food area.", "occurrence_notes":null, "guid":"149535-21906578@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/149535", "building_id":"1000406", "building_name":"Lurie Biomedical Engineering (formerly ATL)", "campus_maps_id":"7", "room":"Atrium", "location_name":"Lurie Biomedical Engineering (formerly ATL)", "has_livestream":0, "cost":"", "tags":["Michigan Engineering","Basic Science","Medicine","engineering","engineer","bme","Biotechnology","Biosciences","Bioninterfaces","biomedical engineering","biomedical","Biology","Biointerfaces"], "website":"http:\/\/bme.umich.edu", "sponsors":[ { "group_name":"Biomedical Engineering", "group_id":"1143", "website":"https:\/\/www.facebook.com\/profile.php?id=100094127215673" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/07\/event_149535_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2026\/07\/event_149535_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/07\/event_149535_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2026\/07\/event_149535_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2026\/07\/event_149535_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2026\/07\/event_149535_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2026\/07\/event_149535_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2026\/07\/event_149535_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2026\/07\/event_149535_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2026\/07\/event_149535_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2026\/07\/event_149535_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2026\/07\/event_149535_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2026\/07\/event_149535_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2026\/07\/event_149535_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2026\/07\/event_149535_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2026\/07\/event_149535_original-1.png" }, "occurrence_count":1, "first_occurrence":21906578 } }