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        "event_title":"CCMB\/DCMB Weekly Bioinformatics Seminar Series featuring Lindsey Muir, PhD (Research Assistant Prof. of Computational Medicine & Bioinformatics)",
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        "combined_title":"CCMB\/DCMB Weekly Bioinformatics Seminar Series featuring Lindsey Muir, PhD (Research Assistant Prof. of Computational Medicine & Bioinformatics): \"Progress and Challenges in Direct Cell Reprogramming\"",
        "event_subtitle":"\"Progress and Challenges in Direct Cell Reprogramming\"",
        "event_type":"Workshop \/ Seminar",
        "event_type_id":"21",
        "description":"Development of cell reprogramming methods is hindered by low efficiency and the challenge of analyzing rare cells that have yet unknown phenotypes. While cells in a typical biosample can be identified using unbiased single-cell transcriptomics, annotation itself relies on known gene expression signatures. Cells that begin to reprogram within a larger population remain indiscernible using this approach. Work in this area illuminates the unknowns related to our understanding of cell identity and heterogeneity. I will discuss our recent work, including direct cell reprogramming to human hematopoietic stem cells, future directions, and key barriers to discovery in the field.",
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        "room":"4B700",
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        "tags":["Basic Science","Bioinformatics","Biology","Biomedical Engineering","biomedical research","Biosciences","Computational Science"],
        "website":"https:\/\/medschool.umich.edu\/events\/ccmb-seminar-series\/ccmb-seminar-lindsey-muir-phd\/2026-10-28",
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                "website":"http:\/\/www.ccmb.med.umich.edu\/"                }                    ],
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