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DTSTAMP:20260331T142224
DTSTART;TZID=America/Detroit:20260407T120000
DTEND;TZID=America/Detroit:20260407T130000
SUMMARY:Lecture / Discussion:Applied Physics | Decoding how cell signaling controls differentiation in stem cell models for early human development
DESCRIPTION:The remarkable capacity of mammalian embryos to self-organize is preserved in human pluripotent stem cells (hPSC)\, which on micropatterned surfaces form structures with reproducible spatial organization that resemble the early embryo. hPSCs therefore provide a powerful model to study the mechanisms of early human development. Secreted signaling molecules play a key role in orchestrating development\, but a quantitative understanding of how they do this is lacking. According to current paradigm\, it is the level of signaling that determines a cell’s response\, but this model fails to correctly predict cell fate decisions. Two shortcomings may explain this. First\, the model is static\, ignoring the essential role of time. Second\, different signals have typically been studied separately\, despite the fact that they act in a fundamentally combinatorial manner. To address this\, my lab has developed methods to track signaling in hPSCs over time and to measure many signals at once in snapshots. I will discuss how we are applying these methods to build a quantitative understanding of how cell signaling controls cell fate decisions.
UID:147302-21900661@events.umich.edu
URL:https://events.umich.edu/event/147302
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Applied Physics,Biomedical Engineering,Physics,Seminar
LOCATION:West Hall - 340
CONTACT:
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DTSTAMP:20260224T150916
DTSTART;TZID=America/Detroit:20260409T110000
DTEND;TZID=America/Detroit:20260409T120000
SUMMARY:Workshop / Seminar:Quantum Research Institute | Quantum Spin-Mechanics with Color Centers in Diamond: A Potential Platform for Quantum Computing
DESCRIPTION:In-Person: West Hall 411\nZoom: https://umich.zoom.us/j/91761768567?jst=2\n\nAbstract:\nIn a spin-mechanical system\, electron spins are coupled to vibrations of a nanomechanical resonator.  Coherent interactions between single spins and single phonons take place in the quantum regime of spin-mechanics.  A network of these resonators can enable phonon-mediated coupling between distant electron spin\, leading to a mechanical quantum network of spin qubits and providing an experimental platform for developing spin-based quantum computers.  \nIn this talk\, I will discuss our recent advance in achieving ultracoherent GHz diamond nanomechanical resonators and in developing mechanical quantum networks of spin qubits in diamond.  Localization and localization phase transitions induced by deterministic onsite potentials in a mechanical network are also exploited for the realization of extended network connectivity\, which is deemed essential for large-scale fault tolerant quantum computers. \n\nBio:\nHailin Wang received B.S. and Ph.D. degrees in physics from the University of Science and Technology of China and the University of Michigan in 1982 and 1990\, respectively. He was a research investigator at the University of Michigan and subsequently a staff consultant at AT&T Bell Laboratories. He joined the University of Oregon in 1995 where he is now a professor of physics. Dr. Wang has made important contributions to the current understanding of coherent as well as incoherent optical processes in semiconductor nanostructures. He also made the first experimental demonstration of amplitude squeezed light from an injection-locked diode laser and developed a fused silica optical resonator that feature highly directional evanescent tunneling. His work on exciton spin coherence and biexciton coherence has recently led to the first demonstration of electromagnetically induced transparency for interband optical transitions in semiconductors. His current research interest includes optical manipulation of quantum coherences in semiconductors and especially its application in both classical and quantum information processing. Dr. Wang is a recipient of an NSF-CAREER award and is a fellow of the Optical Society of America.
UID:142261-21890281@events.umich.edu
URL:https://events.umich.edu/event/142261
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Astronomy,Chemistry,Computer Science And Engineering,Electrical And Computer Engineering,Electrical Engineering And Computer Science,Physics,Quantum,Quantum Computing,Quantum Science
LOCATION:West Hall - 411
CONTACT:
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