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DTSTAMP:20230206T111847
DTSTART;TZID=America/Detroit:20230310T120000
DTEND;TZID=America/Detroit:20230310T130000
SUMMARY:Workshop / Seminar:MCDB Seminar> Building the epithelial brush border\, one microvillus at a time
DESCRIPTION:Hosts: Ann Miller and Simon P. Hogan \nMolecular Cellular Pathology series
UID:103023-21805719@events.umich.edu
URL:https://events.umich.edu/event/103023
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biosciences
LOCATION:Biological Sciences Building - 1060
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20230213T160949
DTSTART;TZID=America/Detroit:20230313T150000
DTEND;TZID=America/Detroit:20230313T163000
SUMMARY:Workshop / Seminar:Connell Memorial Lecture> Ribosome collisions as a signaling hub to impact cell fate
DESCRIPTION:Rachel Green began her scientific career majoring in chemistry as an undergraduate at the University of Michigan. Her doctoral work was performed at Harvard in the laboratory of Jack Szostak where she studied RNA enzymes and developed methodologies for evolving RNAs in vitro. She came to the Johns Hopkins University School of Medicine in 1998 following post-doctoral work in Harry Noller’s lab at University of California Santa Cruz where she began her work on ribosomes. Her laboratory is interested in deciphering the molecular mechanisms that are at the heart of protein synthesis and its regulation across biology. Most recently\, her work has focused on ribosome-mediated quality control systems that are triggered on difficult-to-translate mRNA sequences deriving from genetic or environmental insults. She has found that such translational distress leads not only to mRNA-specific QC events\, but also to the activation of cell-wide signaling and transcriptional responses\, mediated by factors that specifically bind to colliding ribosomes. Her laboratory uses both biochemical\, genetic\, proteomic and genomic approaches to get at these questions in bacterial and eukaryotic systems.\n\nShe is a Bloomberg Distinguished Professor of molecular biology and genetics at the Johns Hopkins University School of Medicine and a HHMI Investigator.\n\nLecture is made possible by a gift from her family in memory of Priscilla Connell\, a renowned nature photography.\n\nHost: Morgan DeSantis
UID:104914-21810438@events.umich.edu
URL:https://events.umich.edu/event/104914
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biosciences
LOCATION:Rackham Graduate School (Horace H.) - Amphitheatre
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20230313T181510
DTSTART;TZID=America/Detroit:20230313T160000
DTEND;TZID=America/Detroit:20230313T173000
SUMMARY:Other:Accelerating Drug Discovery: Innovations in Catalysis and High-Throughput Experimentation
DESCRIPTION:Organic\nDipannita Kalyani (Merck)
UID:105372-21811623@events.umich.edu
URL:https://events.umich.edu/event/105372
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biosciences
LOCATION:Chemistry Dow Lab - 1640
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20230302T153630
DTSTART;TZID=America/Detroit:20230314T113000
DTEND;TZID=America/Detroit:20230314T130000
SUMMARY:Workshop / Seminar:Controlling stochastic biophysical processes\, from protein folding to evolution
DESCRIPTION:Abstract: The chemical reaction networks that regulate living systems are all stochastic to varying degrees.  The resulting randomness affects biological outcomes at multiple scales\, from the probability that a single protein molecule successfully finds its folded state to the evolutionary trajectory of a population of cells.  Understanding how the distribution of these outcomes changes over time is often difficult\, and achieving control over this distribution via external interventions is an even more complex challenge.  Intriguingly\, this problem has close parallels in a very different domain:  manipulating quantum states for applications like quantum computing and cold atom transport.  In this talk we show how one can translate quantum control into the classical realm of biology\, giving us a novel tool for steering biological processes.  We illustrate this idea through two examples:  the first is controlling the distribution of genetic variants in an evolving cellular population.  This is motivated by recent efforts to combat antibiotic resistance via therapies that guide the evolution of pathogens toward maximized drug sensitivity.  The second example involves controlling the distribution of protein folding states using so-called molecular chaperones:  protein enzymes that facilitate the unfolding or disaggregating of misfolded proteins.  The theoretical framework behind these two examples is quite general\, and can in principle be used in many other biophysical problems.  Finally\, we discuss ongoing work to explore the thermodynamic costs associated with control.
UID:105666-21812662@events.umich.edu
URL:https://events.umich.edu/event/105666
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biosciences
LOCATION:Weiser Hall - 747
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20230314T181510
DTSTART;TZID=America/Detroit:20230314T113000
DTEND;TZID=America/Detroit:20230314T130000
SUMMARY:Other:Unconventional Site Selectivity in Cross-Couplings of Dihaloheteroarenes
DESCRIPTION:Heteroarenes are ubiquitous motifs in high-value small molecules including pharmaceutical drugs and agrichemicals. Elaboration of halogenated heteroaromatic cores can be achieved through cross-coupling reactions\, which are among the most widely used methods in organic synthesis. However\, when two or more halides are present on the substrate\, controlling site selectivity becomes critical. In fact\, cross-couplings often follow a predictable selectivity pattern. For many dihalogenated heteroarenes\, methods do not exist to reliably invert the conventional pattern to achieve cross-coupling at the \\"less reactive\\" C—X bond. Herein we describe new catalyst-controlled strategies to accomplish this goal\, together with mechanistic studies to explain the origin of the selectivity inversion.                        \n                       \n\nSharon Neufeldt (Montana State University)
UID:95717-21790782@events.umich.edu
URL:https://events.umich.edu/event/95717
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biosciences
LOCATION:Chemistry Dow Lab - 1300
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20230310T134600
DTSTART;TZID=America/Detroit:20230314T120000
DTEND;TZID=America/Detroit:20230314T130000
SUMMARY:Workshop / Seminar:EEB Tuesday Lunch Seminar - Hybrid - \"Region-wide climate-driven grassland community shifts in a biodiversity hotspot\"
DESCRIPTION:Our weekly lunch seminar series featuring internal speakers in the field of ecology and evolutionary biology. This seminar will be in-person and livestreaming on Zoom.\n\nAbstract:\nEcological communities have been shifting rapidly under recent climate change with alarming consequences for biodiversity and ecosystem services\, yet the generality and causality of such shifts have to be demonstrated. We focus on grasslands in the California Floristic Province\, a global biodiversity hotspot spanning 300\,000 km2\, where considerable climate warming and drying have occurred. We compiled long-term grassland community composition data from 12 observational sites and a warming experiment\, estimated hundreds of species’ climate niches from millions of occurrence records\, and analyzed changes in community composition and species gain and loss in reference to their climate distributions. We show that these grassland communities experienced significant shifts toward species tolerant of warmer and drier conditions\, at a pace similar to climate warming and drying. The consistent observational and experimental evidence establish grassland community shift as a predictable fingerprint of climate change.
UID:97033-21793711@events.umich.edu
URL:https://events.umich.edu/event/97033
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biosciences
LOCATION:Biological Sciences Building - 1010
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20230315T181512
DTSTART;TZID=America/Detroit:20230315T160000
DTEND;TZID=America/Detroit:20230315T173000
SUMMARY:Other: 3rd Year Materials Student Seminars 
DESCRIPTION:Materials\n 
UID:105060-21810656@events.umich.edu
URL:https://events.umich.edu/event/105060
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biosciences
LOCATION:Chemistry Dow Lab - 1640 
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20230226T075947
DTSTART;TZID=America/Detroit:20230316T110000
DTEND;TZID=America/Detroit:20230316T120000
SUMMARY:Livestream / Virtual:Role of cytosolic phospholipase A2α during neutrophil chemotaxis
DESCRIPTION:Dissertation Defense\n\nWe are pleased to announce that Fatima Javed\, Ph.D. Candidate\, (Carole Parent\, Ph.D.\, Mentor)\, will present her Dissertation Defense titled \"Role of cytosolic phospholipase A2α during neutrophil chemotaxis\" on Thursday\, March 16\, 2023 from 11 a.m.-12:00 p.m.\, via live stream: Livestream: https://umich.zoom.us/j/93732889427 Passcode CDB\, and in Person at BSRB Kahn Auditorium.\n\nDissertation Committee\nCarole Parent (Mentor)\nBilly Tsai (Chair)\nLois Weisman\nMarc Peters-Golden
UID:105458-21811900@events.umich.edu
URL:https://events.umich.edu/event/105458
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biosciences
LOCATION:Taubman Biomedical Science Research Building
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20221128T125429
DTSTART;TZID=America/Detroit:20230316T150000
DTEND;TZID=America/Detroit:20230316T160000
SUMMARY:Workshop / Seminar:EEB Thursday Seminar - Hybrid: Ecological responses in a warmer and drier future: *from individuals to community to ecosystem level functions*
DESCRIPTION:Our weekly seminar series featuring internal and external speakers in the field of ecology and evolutionary biology. This seminar will be in-person and livestreaming on Zoom (link this page).\n\nAbstract:\nUnderstanding the role of climatic gradients shaping species interactions and system-level structure and function has been the thrust of ecological studies. We are exploring how experimental warming and drought shapes the structure and function of montane meadows and temperate prairies. By tracking individual abundance and functional traits across plant communities\, alongside ecosystem carbon dynamics\, we address how climatic change influences prairies\nand meadows across levels of biological organization. We find that while individuals and communities are shifting under climatic change\, ecosystem functions lag behind. \n\nContact eebsemaccess@umich.edu for Zoom password at least 2 hours prior to event.
UID:96710-21793109@events.umich.edu
URL:https://events.umich.edu/event/96710
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biosciences
LOCATION:Biological Sciences Building - 1010
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20230309T162052
DTSTART;TZID=America/Detroit:20230317T100000
DTEND;TZID=America/Detroit:20230317T110000
SUMMARY:Workshop / Seminar:EEB Student Dissertation Defense: Toxic Forms Most Beautiful: The Evolutionary Dynamics of Rear-Fanged Snake Venoms.
DESCRIPTION:Peter presents their dissertation defense.
UID:104542-21809579@events.umich.edu
URL:https://events.umich.edu/event/104542
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biosciences
LOCATION:Biological Sciences Building - 5150
CONTACT:
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