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DTSTART:20070311T020000
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DTSTAMP:20250410T100925
DTSTART;TZID=America/Detroit:20250418T100000
DTEND;TZID=America/Detroit:20250418T120000
SUMMARY:Workshop / Seminar:EEB Student Dissertation Defense - Selections in molecular and phenotypic evolution
DESCRIPTION:Dissertation Title: Selections in molecular and phenotypic evolution\n\nDissertation Abstract: Selection plays an undoubtedly important role in evolution. My dissertation explores the pattern and impact of selection at both molecular and phenotypic levels. In Chapter 1\, I challenged the neutral theory of molecular evolution by demonstrating that beneficial mutations are way more abundant than previously assumed. I proposed an adaptive tracking theory to reconcile this finding with the low substitution rate inferred from comparative genomic patterns\; under this theory\, a natural population is always adapting to the rapidly changing environment. In Chapter 2\, I investigated the genetic maintenance of human same-sex sexual behavior (SSB) and showed that modern contraception had disrupted previously hypothesized evolutionary mechanisms that maintained SSB-associated alleles. In Chapter 3\, I further distinguished between bisexual behavior (BSB) and exclusive SSB (eSSB) in their genetic basis\, finding that BSB-associated alleles may confer reproductive advantages whereas eSSB-associated alleles are likely under negative selection. In Chapter 4\, I examined the genetic architecture of the human sex ratio\, identified the impact of large measurement error in inferring the heritability of sex ratio\, and provided genomic evidence supporting Fisher’s principle. Finally\, I addressed methodological aspects of evolutionary analysis: in Chapter 5\, I uncovered biases in inferring fitness landscape ruggedness due to measurement errors and proposed a correction\; in Chapter 6\, I introduced “effective fitness” as a more informative metric to quantify fluctuating selection with genetic drift. Collectively\, these findings underscore the pervasive role of natural selection in both molecular and phenotypic evolution and offer new frameworks for understanding
UID:134778-21875096@events.umich.edu
URL:https://events.umich.edu/event/134778
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:department of ecology and evolutionary biology,Graduate Students,Free,eeb,Ecology And Evolutionary Biology,Ecology & Biology,Dissertation,developmental biology,Bsbsigns
LOCATION:Rackham Graduate School (Horace H.) - Earl Lewis Room
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20250415T142445
DTSTART;TZID=America/Detroit:20250418T100000
DTEND;TZID=America/Detroit:20250418T110000
SUMMARY:Social / Informal Gathering:Fragel Friday
DESCRIPTION:One more fragel. One more Friday. One more reason to smile.\nJoin connect@michiganengineering for the last Fragel Friday of the semester this Friday (4/18) at 10 AM—your final chance to score a fresh\, FREE fragel before we break for the summer (limited quantities).\n\nWhether you missed us last week or just can’t get enough\, we’ve got you covered. Swing by the Grove\, fuel up\, and catch up with friends before finals take over.\n\nThis is it until September—don’t miss your fragel fix!
UID:135018-21875962@events.umich.edu
URL:https://events.umich.edu/event/135018
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Undergraduate Students,Undergraduate,Outdoors,North Campus,Michigan Engineering,In Person,Graduate Students,Graduate,Free,Food,Engineering,Community Engagement,Community,College Of Engineering,Breakfast
LOCATION:The Grove
CONTACT:
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