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DTSTAMP:20260111T114049
DTSTART;TZID=America/Detroit:20260205T143000
DTEND;TZID=America/Detroit:20260205T160000
SUMMARY:Workshop / Seminar:Culture\, History and Politics (CHiP)
DESCRIPTION:- January 15: Cho Han\n- January 22: Marni Morse\n- January 29: Jiyeon Lee\n- February 5: Tess Hamilton\n- February 12: Álvaro Cabrera\n- February 19: Jarron Long\n- February 26: Xianni Zhang\n- March 12: Sarah Farr and Christian Castro-Martinez\n- March 19: Danyelle Reynolds\n- March 26: Vanessa Jiménez-Read\n- April 2: Abigail Skalka and Julieta Goldenberg\n- April 9: Eric Freeburg\n- April 16: TBD
UID:143661-21893602@events.umich.edu
URL:https://events.umich.edu/event/143661
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Graduate Student
LOCATION:LSA Building - 4147
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20260127T070323
DTSTART;TZID=America/Detroit:20260205T150000
DTEND;TZID=America/Detroit:20260205T160000
SUMMARY:Workshop / Seminar:Biomedical Engineering (BME 500) Seminar Series
DESCRIPTION:Brain tumors are organized as active nematic liquid crystals\n\nAbstract:\nWhether gliomas consist of random accumulations of cells or are self-organizing remains unknown.  If large scale order exists\, it should manifest as invariant structures across different tumors. Recently\, we described the existence of oncostreams\, fascicles of elongated mesenchymal-like cells that are found in gliomas in both rodent and human tumors. In this presentation\, I will discuss that glioma brain tumors in vivo\, and in vitro\, are structured as active nematic liquid crystals. Building on our previous work that gliomas exhibit self-organized\, aligned\, multicellular structures\, termed oncostreams\, I will show that gliomas display nematic order\, topological defects\, disclinations\, and quasi-long range order in 2D and in 3D. Significantly\, the amount of nematic order scales with tumor aggression - suggesting crystalline order contributes to tumor malignancy - constituting a novel potential therapeutic target for this incurable cancer. Potential novel therapeutic approaches based on this new understanding of the structure of gliomas will be discussed. \n\nBio:\nDr. Lowenstein graduated MD\, Ph.D. from the University of Buenos Aires\, Argentina. Following postdoctoral work at The Johns Hopkins University\, NIH\, and Oxford University he opened his first lab at the University of Dundee\, Scotland. Subsequently\, he has taught and researched at the University of Wales\, Cardiff\, the University of Manchester\, UK\, and UCLA and Cedars-Sinai Medical Center\, in Los Angeles\, CA. He has been at the University of Michigan since 2011. His interests lie in understanding and curing brain tumors. Most recently\, he has been exploring the physical organization of brain tumors\, as will be discussed during his presentation.
UID:144608-21895563@events.umich.edu
URL:https://events.umich.edu/event/144608
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biointerfaces,Biology,biomedical,biomedical engineering,Bioninterfaces,Biosciences,Biotechnology,bme,engineer,engineering,Medicine,Michigan Engineering,seminar
LOCATION:Lurie Biomedical Engineering (formerly ATL) - 1130
CONTACT:
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