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DTSTAMP:20240618T183120
DTSTART;TZID=America/Detroit:20240603T160000
SUMMARY:Careers / Jobs:MBA WEEK 2024
DESCRIPTION:Join us for Leland's FREE MBA Week\, 10 live online sessions covering the most important aspects of the MBA admissions process.This event will feature former admissions committee members and MBA application experts giving tactical insights and tips to get into top MBA programs. Example sessions include: “Writing Standout Essays”\, “HBS 2+2 Office Hours”\, “Letter of Recommendation Deep Dive” and more.All registrants will also receive free example essays\, resources and guides!
UID:122282-21848548@events.umich.edu
URL:https://events.umich.edu/event/122282
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:
LOCATION:
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BEGIN:VEVENT
DTSTAMP:20240528T093819
DTSTART;TZID=America/Detroit:20240603T160000
DTEND;TZID=America/Detroit:20240603T170000
SUMMARY:Workshop / Seminar:RNA Innovation Seminar: Alexandra Piotrowski-Daspit\, University of Michigan
DESCRIPTION:HYBRID SEMINAR:\nIn-person: BSRB\, Kahn Auditorium \nZoom: https://umich.zoom.us/webinar/register/WN_mr2BfdnHQ9OCJN7Eg7pk4Q\n\nAbstract: The primary barrier for clinical translation of RNA therapeutics remains delivery to target tissues in vivo. Upon entering the body\, delivery vehicles encounter extracellular and intracellular barriers. It is also unclear how carrier design features impact physiological interactions with biological systems\, highlighting the need for studies that elucidate these structure-function relationships. In this seminar\, I will describe our work on developing polymeric nanoparticles (NPs) to deliver therapeutic RNAs to a variety of tissues following local and systemic IV administration. We find that gene therapy can be significantly enhanced using a new class of polymeric vehicles consisting of poly(amine-co-ester) (PACE) polymers that are designed for safe and effective nucleic acid delivery. We have also developed tools to study nanomaterial-biology interactions in animal models\, including a high-throughput quantitative microscopy-based platform to measure circulation half-life and biodistribution in vivo. This tool\, alongside the development of novel polymeric carriers\, can be used to study the structure-function relationships that guide the physiological fate of NPs in order to rationally design more effective delivery vehicles for RNA delivery.\n\nKeywords: RNA therapeutics\, in vivo delivery\, polymeric nanoparticles (NPs)\, nanomaterial-biology interactions
UID:110276-21824711@events.umich.edu
URL:https://events.umich.edu/event/110276
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biosciences
LOCATION:Taubman Biomedical Science Research Building - Kahn Auditorium
CONTACT:
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