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DTSTAMP:20260921T131131
DTSTART;TZID=America/Detroit:20260923T120000
DTEND;TZID=America/Detroit:20260923T130000
SUMMARY:Workshop / Seminar:Math Biology Seminar & Working Group: Parameter Identifiability and Inference in Models of Human Physiology
DESCRIPTION:How do we expose the underlying dynamics of the human body when direct measurement is difficult? From the fragile lungs of extremely preterm infants to the complex processes of the human brain\, clinical data is often noisy\, indirect\, and difficult to interpret. This talk explores how integrating mechanistic mathematical modeling with data-driven statistical inference can bridge the gap between raw biological signals and patient-specific clinical decision making. Specifically\, this talk will briefly explore mechanistic and data-driven approaches to two case studies: i) the suppressed respiratory system of the preterm infant and ii) Parkinsonian spiking dynamics in macaque basal ganglia. Computational approaches such as these are increasingly implemented to understand human pathophysiology\, but corresponding models depend on reliable estimation of model parameters from available data\, which raises two challenges in model identification: parameter identifiability and parameter sensitivity\, both of which determine whether parameter estimation is even feasible in a given model. By tackling these challenges with robust mathematical frameworks for model analysis\, we can explore resulting models for behavioral interactions between model components\, which would otherwise be impossible in a physical setting. This talk will briefly explore distinct approaches to estimating patient- specific parameter values while addressing these challenges in both mathematical (respiratory study) and statistical (Parkinsonian study) modeling frameworks.
UID:152417-21913707@events.umich.edu
URL:https://events.umich.edu/event/152417
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Mathematical Modeling,biophysics,Data Science,Dynamics,Mathematical Biology
LOCATION:1100 North University Building - 1570
CONTACT:
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DTSTAMP:20260728T111105
DTSTART;TZID=America/Detroit:20260923T120000
DTEND;TZID=America/Detroit:20260923T130000
SUMMARY:Well-being:Productivity and Stress
DESCRIPTION:Feeling overwhelmed by college? Join the Productivity and Stress wellness group to learn realistic ways to manage stress and improve your productivity. This FREE in-person educational wellness group is for students only and will include an interactive presentation facilitated by staff from the Eisenberg Family Depression Center and is a collaborative service with U-M Engineering's C.A.R.E. Center and the Newnan Academic Advising Center.\n\nRegistration is not required for in-person wellness groups\, but is recommended so there is enough lunch for all attendees. You can register using the link. Learn more at campusmindworks.org
UID:149351-21906264@events.umich.edu
URL:https://events.umich.edu/event/149351
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Health & Wellness,Undergraduate,Free Food,Free,Food,Campus Mind Works,Workshop,Wellness,Well-being,Stress,In Person,Productivity,North Campus,Mental Health
LOCATION:Chrysler Center - 265
CONTACT:
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