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BEGIN:VEVENT
DTSTAMP:20260820T165408
DTSTART;TZID=America/Detroit:20261020T090000
DTEND;TZID=America/Detroit:20261020T200000
SUMMARY:Exhibition:Faster and More Fun: American Home Cooking in the 1920s
DESCRIPTION:Visit the Hatcher Gallery Exhibit Room to see historical materials that illustrate women’s changing relationship with food\, cooking\, and technology during the heady decade of the 1920s\, sandwiched between WWI and the Great Depression. This exhibit features materials from the Janice Bluestein Longone Culinary Archive\, as well as select items from the Art\, Architecture\, and Engineering Special Collections and the Transportation History Collection.\n\nAs America rang in a new decade in the 1920s\, cookbook authors and appliance manufacturers stood ready to offer the newly emancipated and forward-thinking American woman a vision for her future\, a vision that would be scientifically  grounded\, speedy enough to make time for leisure as well as housework\, and guaranteed to bring fun to that most humdrum of chores: planning and preparing meals for a family three times a day\, 365 days a year.
UID:150658-21909800@events.umich.edu
URL:https://events.umich.edu/event/150658
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Culinary History,Free,Library
LOCATION:Hatcher Graduate Library - Hatcher Gallery Exhibit Room, 1st Floor
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260728T142037
DTSTART;TZID=America/Detroit:20261020T090000
DTEND;TZID=America/Detroit:20261020T170000
SUMMARY:Exhibition:Grand Vision
DESCRIPTION:Visiting artist Olayami Dabls is a storyteller\, curator\, educator\, and mentor. He is the founder of the MBAD African Bead Museum in Detroit. Through material culture\, Dabls presents commentary on the past\, present\, and future from African and African-American perspectives\, with the understanding that generations of African ancestors used visual materials to convey information about their identity as well as send messages for healing and protection. Dabls is a luminary\; for decades he has re-imagined what a museum space can be\, accessible to everyone\, free from the underpinnings of colonialism and the Western\, often white\, frame. *Grand Vision* includes a conceptual installation in the Gallery\, presenting Dabls’s own work in visual conversation with African beads and artifacts from Dabls’s Bead Museum collections. \n\nAdditionally\, Dabls’s iconic outdoor sculpture *Iron Teaching Rocks Table Manners* will be installed on the U-M campus grounds near UMMA\, at the intersection of State Street and South University from September 17- October 11\, 2026. The project’s range intends to more fully articulate the many facets of Dabls’ creative practice\, and the overlay of art\, history\, identity\, community\, and healing.
UID:149620-21906799@events.umich.edu
URL:https://events.umich.edu/event/149620
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:African American,Art,Detroit,Exhibition,Humanities,Michigan Arts Festival,Visual Arts
LOCATION:202 S. Thayer - Institute for the Humanities Gallery
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T182157
DTSTART;TZID=America/Detroit:20261020T090000
DTEND;TZID=America/Detroit:20261020T163000
SUMMARY:Conference / Symposium:Student Life Facilitation Training October 2026
DESCRIPTION:The Student Life Facilitation Committee and Student Life Professional Development are proud to announce that we are offering a staff-oriented facilitation training opportunity once again! A similar training has been offered to students and we have adapted the curriculum to provide staff with the skills and knowledge necessary to build confidence and ability in facilitation.The training will take place on Monday\, October 19 & Tuesday\, October 20\, 9:00am-4:30pm in the Connector Multipurpose Room. Attendance is required for the full training. A light breakfast & lunch will be provided.The training is comprised of a 16-hour training curriculum designed to: 1) prepare participants to facilitate dialogues\, meetings\, and workshops involving two or more individuals\; 2) be available to staff within Student Life\; 3) supplement unit-specific trainings\; 4) maximize divisional resources\; and 5) be module-based and repeatable.We encourage you to register\, participate\, and gain invaluable skills throughout the training. This training is free to Student Life staff and $100 for staff in other departments. We have a minimum cap of 10 and a maximum cap of 16 participants. If we do not meet the minimum we will need to cancel the training. If we meet the maximum you will have the opportunity to join a waitlist. Please communicate any accessibility/accommodation needs to the coordinating group at slfacilitation@umich.edu at least two weeks in advance of the training or as soon as possible. Registration for this training closes on October 12th.
UID:149508-21906538@events.umich.edu
URL:https://events.umich.edu/event/149508
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Sessions
LOCATION:
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T093359
DTSTART;TZID=America/Detroit:20261020T093000
DTEND;TZID=America/Detroit:20261020T110000
SUMMARY:Workshop / Seminar:CoderSpaces - Tuesdays
DESCRIPTION:Are you grappling with a piece of code\, trying to compute on a cluster\, or just getting started with a new method such as machine learning? Then we might have just the right space for you.\n\nAll members of the U-M community are invited to join our weekly virtual CoderSpaces to get research support and connect with others.\n\nTuesdays\, 9:30-11 a.m. ET\, via Zoom (Meeting ID: 513 103 7575)\nWednesdays\, 1:30-3 p.m. ET\, via Zoom (Meeting ID: 513 103 7575)
UID:152608-21914058@events.umich.edu
URL:https://events.umich.edu/event/152608
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Ai,Artificial Intelligence,Data,Data Analysis,Data Collection,Data Curation,Data Linkage,Data Management,Data Science,Great Lakes Cluster,High Performance Computing,Machine Learning,Social Science,Social Sciences,Statistics
LOCATION:Off Campus Location - https://umich.zoom.us/j/5131037575?omn=94024500517
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T182157
DTSTART;TZID=America/Detroit:20261020T100000
DTEND;TZID=America/Detroit:20261020T111500
SUMMARY:Conference / Symposium:2026 Ethics & Compliance Week
DESCRIPTION:The Ethics\, Integrity\, and Compliance Office is hosting the inaugural Ethics & Compliance Week at the University of Michigan. Please join us in supporting the university through ethics and compliance educational sessions. 
UID:148923-21906047@events.umich.edu
URL:https://events.umich.edu/event/148923
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Sessions
LOCATION:2nd Floor | Pendleton Room
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260824T112111
DTSTART;TZID=America/Detroit:20261020T100000
DTEND;TZID=America/Detroit:20261020T113000
SUMMARY:Workshop / Seminar:Introduction to Digital Accessibility
DESCRIPTION:Course details and registration are available on the Organizational Learning website.
UID:150780-21910162@events.umich.edu
URL:https://events.umich.edu/event/150780
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Accessibility,Digital Accessibility,Information and Technology
LOCATION:Off Campus Location
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260914T165019
DTSTART;TZID=America/Detroit:20261020T100000
DTEND;TZID=America/Detroit:20261020T170000
SUMMARY:Well-being:Pictured Rocks Fall Break
DESCRIPTION:Pictured Rocks Fall Break is a five-day expedition from October 16–20\, 2026.  to one of Michigan's most breathtaking landscapes during the peak of fall color.\n\nThroughout the long weekend\, you'll hike through colorful autumn forests\, discover hidden coves\, and take in sweeping views from cliffs rising nearly 200 feet above the crystal-clear waters of Lake Superior. Register by October 6\, 2026 to secure your spot! Cost: $755\n\nThis expedition offers two ways to experience Pictured Rocks. Approximately 8–10 participants will backpack a section of the lakeshore trail\, carrying everything needed for several days in the backcountry while camping at remote sites. \n\nThe remaining participants will establish a comfortable tent basecamp\, explore the region through day hikes and scenic destinations\, and support the backpacking team with transportation and logistics. \n\nThe program takes place October 16–20\, 2026. Participants will spend four nights tent camping throughout Pictured Rocks National Lakeshore before returning to the Adventure Leadership Resource Center located on Central Campus during the evening on Tuesday\, October 20.\nThe program includes transportation\, meals during the expedition\, campsite reservations\, all group camping equipment\, and the opportunity to borrow personal camping gear — including a backpack\, sleeping bag\, sleeping pad\, and headlamp — at no additional cost. Personal clothing and toiletries are not included.
UID:152142-21913138@events.umich.edu
URL:https://events.umich.edu/event/152142
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Adventure Leadership,Community,Leadership,Nature,outdoor adventures,Outdoors,recreation,Well-being,Wellness
LOCATION:Off Campus Location
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260911T131259
DTSTART;TZID=America/Detroit:20261020T120000
DTEND;TZID=America/Detroit:20261020T160000
SUMMARY:Exhibition:“Who Counts? A History of Voting in America”
DESCRIPTION:Changes over the course of the nineteenth century in how Americans voted\, from voice vote to public ballot box to private voting booth\, also saw changes in the material culture that surrounded voting. Ballots and ballot boxes\, campaign pins and ribbons\, blank lists and pre-printed party tickets\, lanterns and banners–the creative forces of the American print industry filled the country’s cities and small towns with the ephemera of electioneering.\n\nAs you look at the items in this exhibit\, think about what they tell us about how Americans in the past felt about voting\, and about how voting felt. How did Election Days feel when they were full of parades and music and public drinking? What was it like to vote when everyone around you knew who you voted for? And\, most of all\, who counted as a voter\, and who did the counting?\n\nOn view September 11-December 22\, weekdays from 12-4 pm.
UID:152024-21912668@events.umich.edu
URL:https://events.umich.edu/event/152024
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:american culture,american history,Americana,Event,Exhibit,Exhibition,history,In Person,libraries,Library,Tour,William L Clements
LOCATION:William Clements Library
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260717T094617
DTSTART;TZID=America/Detroit:20261020T120000
DTEND;TZID=America/Detroit:20261020T130000
SUMMARY:Workshop / Seminar:Avoiding Assumptions & Normalizing Disability
DESCRIPTION:Join this practical\, perspective-shifting workshop to explore how everyday assumptions can unintentionally undermine disability inclusion. Together\, we’ll examine common misconceptions—such as assuming someone using a mobility cane needs assistance\, or that two people with the same diagnosis will have the same needs—and consider how these assumptions can shape our interactions. \n\nParticipants will learn how viewing disability as a natural part of human diversity can help us respond with greater respect\, awareness\, and openness. This workshop offers an opportunity to reflect\, challenge assumptions\, and build more inclusive practices in everyday settings.\n\nAmerican Sign Language (ASL) interpreting services and Communication Access Realtime Translation (CART) captioning services will be provided. If you need additional accommodations to participate in this webinar\, please email the ADA Coordinator at ADAcoordinator@umich.edu.
UID:149433-21906413@events.umich.edu
URL:https://events.umich.edu/event/149433
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Accessibility,Culture,Disability,Diversity,Inclusion,Ndeam,Virtual,Workshop
LOCATION:Off Campus Location
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T121523
DTSTART;TZID=America/Detroit:20261020T120000
DTEND;TZID=America/Detroit:20261020T170000
SUMMARY:Exhibition:Cosmo Whyte: Under the Quiet\, Beyond the Eye
DESCRIPTION:\n\nCurated by Srimoyee Mitra\n\nStamps Gallery kicks off the fall 2026 semester with an ambitious mid-career survey of interdisciplinary artist Cosmo Whyte. Born and raised in Jamaica\, Whyte completed a BFA from Bennington College and earned an MFA from the University of Michigan. He is currently a faculty member at the School of the Arts and Architecture\, UCLA.\n\nThis exhibition brings together two central concerns that animate Whyte’s artistic practice: the archive\, both personal and public\, as a site of disturbance\; and migration as a lived experience of refuge\, refusal\, and reinvention. In Whyte’s work\, the archive is never static or neutral. Rather\, it is a contested space where official histories encounter memory\, inheritance\, and the fragments of stories carried across generations. His practice moves within this charged interstitial terrain\, between what has been recorded and what has been remembered\, between institutional knowledge and embodied experience. Whyte invites the viewer to consider the fluidity of geographic borders and layered cultural identities that have persisted despite societal unrest caused by racial and socio-economic hierarchies across generations. In an era of intensified border politics and renewed debates over national identity\, Whyte’s work offers a timely meditation on memory\, movement\, and belonging.\n\nPresented with support from the U-M Institute for Humanities\, the U-M LSA Center for Latin American and Caribbean Studies\, and the U-M Library.
UID:149541-21906621@events.umich.edu
URL:https://events.umich.edu/event/149541
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Art
LOCATION:Off Campus Location
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260917T125554
DTSTART;TZID=America/Detroit:20261020T120000
DTEND;TZID=America/Detroit:20261020T130000
SUMMARY:Livestream / Virtual:Woll Family Speaker Series Presents:  Dr. Nathan Houchens
DESCRIPTION:About This Event\nIs medicine a sacred practice? Nathan Houchens\, MD\, a Professor of Internal Medicine at the University of Michigan\, thinks so. As the Executive Director of the Sacred Moments Initiative\, he leads a multidisciplinary group devoted to studying\, cataloging\, educating about\, sharing and spreading the message of sacred moments in the clinical world. As part of that work\, he hosts “Boundless Moments\,” a storytelling podcast in which sacred moments come to life through the voices of those who lived them. He also serves as the Acting Chief of Medicine at the Veterans Affairs Ann Arbor Healthcare System and the Director of the Patient Safety and Quality Improvement Learning Program for the Internal Medicine Residency. \n\nDr. Houchens has a wealth of experience in facilitating communication skills training at the local\, regional and national levels. His research and interests revolve around interpersonal relationships\, connection and communication in healthcare settings. He emphasizes the role communication plays in patient and provider satisfaction\, education\, professionalism and humanism. He has found that sacred moments in healthcare tie many of these together. He has authored more than 90 peer-reviewed publications\, one book (\"Teaching Inpatient Medicine: Connecting\, Coaching\, and Communicating in the Hospital\, 2nd Edition\") and three book chapters.
UID:152365-21913591@events.umich.edu
URL:https://events.umich.edu/event/152365
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Boundless Moments,Cataloging,Clinical Education,Health Care Equity,Healthcare,Healthcare Education,Humanism,Internal Medicine,Internal Medicine Residency,Learning Program,Medicine,Patient Safety,Sacred Moments Initiative,Spirituality
LOCATION:Off Campus Location
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T182157
DTSTART;TZID=America/Detroit:20261020T130000
DTEND;TZID=America/Detroit:20261020T143000
SUMMARY:Conference / Symposium:2026 Ethics & Compliance Week
DESCRIPTION:The Ethics\, Integrity\, and Compliance Office is hosting the inaugural Ethics & Compliance Week at the University of Michigan. Please join us in supporting the university through ethics and compliance educational sessions. 
UID:148923-21906048@events.umich.edu
URL:https://events.umich.edu/event/148923
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Sessions
LOCATION:2nd Floor | Pendleton Room
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T182158
DTSTART;TZID=America/Detroit:20261020T130000
DTEND;TZID=America/Detroit:20261020T170000
SUMMARY:Workshop / Seminar:eRPM Proposal Preparation and Unit Review Class
DESCRIPTION:This instructor-led\, hands-on training session covers the process of preparing and submitting proposals using the eResearch Proposal Management (eRPM) system\, including Grants.gov to create and edit a Proposal Approval Form (PAF).
UID:115176-21895523@events.umich.edu
URL:https://events.umich.edu/event/115176
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Sessions
LOCATION:https://umich.zoom.us/j/95002982000
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260921T164909
DTSTART;TZID=America/Detroit:20261020T130000
DTEND;TZID=America/Detroit:20261020T140000
SUMMARY:Livestream / Virtual:Positive Links Speaker Series
DESCRIPTION:Positive Links Speaker Series: The Power of Beliefs: How Seven Core Beliefs Shape Performance\, Well-Being\, and Collective Thriving\nSpeaker: Shawn Achor\nTuesday\, October 20\, 2026\n1:00 - 2:00 p.m. ET\nFree and Online | Registration required to obtain login information\n\nEvent link: https://myumi.ch/pgM7k\n\nPositive Links:\nThe Positive Links Speaker Series\, running for over 22 years with 165 sessions\, is one of the most-watched speaker series at Michigan Ross. Positive Links features distinguished scholars sharing leading ideas in the science of thriving. Learn how to ignite the science of extraordinary organizations catalyzed by human thriving\, together with our community of researchers\, students\, staff\, and leaders.\n\nAbout the talk:\nThis session explores a question at the center of Shawn Achor’s newest research: how much do the beliefs people hold about themselves\, their work\, and their world shape what happens next? Drawing on two decades of research across 51 countries — and work spanning Fortune 100 companies\, NASA\, the NFL\, public school systems\, and six battalions of Marines — Achor introduces a set of seven core beliefs he has found to be most consistently linked to performance\, health\, and well-being\, ranging from the belief that one’s behavior matters to the belief that one’s work is meaningful. He situates these findings against what he calls the Great Drift — the concurrent rise of burnout\, anxiety\, loneliness\, and depression — and argues that as technology has grown more powerful\, beliefs have become more predictive\, not less. You will leave with several research-tested strategies for shifting limiting beliefs in yourself and others\, and a framework for understanding how belief change spreads through teams and organizations.\n\nAbout Achor:\nShawn Achor is the New York Times bestselling author of The Happiness Advantage and Big Potential. Shawn graduated magna cum laude from Harvard and earned a master’s from Harvard Divinity School in Christian and Buddhist ethics. After spending 12 years at Harvard\, Shawn traveled to 50 countries studying how to create an interconnected approach to potential and happiness. He has now worked with over a third of the Fortune 100 companies\, and at places like NASA\, the NFL\, and the Pentagon. Shawn has battle-tested his research in high-challenge environments\, from working with all the public schools in Flint\, Michigan\, to six battalions of Marines at Camp Pendleton\, to government leaders at Camp David\, to students in a shantytown in Soweto\, South Africa\, to hospitals in the wake of a mass shooting in Orlando and the Boston bombing. In every place\, Shawn has found that optimism can be increased through mindset and behavioral change\, and that by creating an interconnected approach to happiness and success\, we shine brighter together. Shawn’s research made the cover of Harvard Business Review\, his TED Talk is one of the most popular of all time with over 20 million views\, and his lecture airing on PBS has been seen by millions.\n\nHost:\nMonica Worline\, Faculty Director\, Center for Positive Organizations\n\nPositive Links Speaker Series Sponsors:\nThe Center for Positive Organizations thanks the Sanger Leadership Center\, Tauber Institute for Global Operations\, and the Zell Lurie Institute for Entrepreneurship for their support of the 2026-27 Positive Links Speaker Series.\n\nPositive Links Series Promotional Partners:\nAdditionally\, we thank Ann Arbor SPARK\, the Managerial and Organizational Cognition (MOC) Division of the Academy of Management\, and the Organization Development and Change (ODC) Division of the Academy of Management for their Positive Links Speaker Series promotional partnerships.
UID:152587-21913967@events.umich.edu
URL:https://events.umich.edu/event/152587
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Business,Center For Positive Organizations,Free,Graduate,Positive Links,Staff,Talk,Undergraduate
LOCATION:Off Campus Location
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260921T234155
DTSTART;TZID=America/Detroit:20261020T143000
DTEND;TZID=America/Detroit:20261020T155000
SUMMARY:Workshop / Seminar:The Distribution of Federally-Insured Mortgages\, 1935-1975: Evidence from Local Land Records (with Jacob Faber\, Andreas Ferrara\, Jonathan Rose\, Thomas Storrs\, Katherine Thomas\, Gabrielle Toborg\, Randall Walsh\, and Wenfei Xu)
DESCRIPTION:This project develops a novel dataset of federally-insured mortgages from 1935 to 1975 by digitizing local land records from county recorders of deeds across a geographically diverse set of U.S. counties. Despite the Federal Housing Administration (FHA) and Veterans Administration (VA) programs accounting for up to 50% of all mortgages for some years during this period\, systematic borrower-level data has been unavailable due to a lack of federal records and decentralized county recording systems. Using a new pipeline that deploys large language models to digitize scanned mortgages\, we identify and extract information from FHA-insured and VA-guaranteed mortgages\, geolocate properties\, and link borrowers to full-count Census data from 1940 and 1950. This produces the first comprehensive address- and borrower-level dataset beyond 1940. We investigate the share of Black borrowers among FHA and VA mortgage recipients\, characterize the spatial distribution of mortgages across neighborhoods that vary in racial composition and HOLC ratings\, and examine the demographic and socioeconomic characteristics of borrowers. The analysis enhances our understanding of how federal housing policy shaped metropolitan development and racial inequality during the New Deal and Civil Rights eras.
UID:150512-21909535@events.umich.edu
URL:https://events.umich.edu/event/150512
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Economics,History,seminar
LOCATION:North Quad - 4325
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T101958
DTSTART;TZID=America/Detroit:20261020T153000
DTEND;TZID=America/Detroit:20261020T170000
SUMMARY:Livestream / Virtual:History in a Time of Forgetting
DESCRIPTION:What do we — as individuals\, communities\, and members of a nation — choose to remember? What\, or who\, is erased from accounts of our shared past? And who benefits from the official and unofficial narratives constructed about the nation’s collective history? \n\nIn 2026\, as the country celebrates the 250th anniversary of the signing of the Declaration of Independence\, the current presidential administration has taken concerted steps to shape and disseminate a very specific version of the nation’s history. Notably\, their efforts involve limiting the stories that are told about our past to conceal difficult truths\, ignoring real complexities from the historical record\, undermining the difficult work of historical research\, and seeking to avoid the processes of interpreting and discussing the meaning of our past. But we can also see the resistance to this rewriting and its erasures in the persistence of existing histories\, as well as the continued proliferation of alternate histories in a variety of spheres and locations that are not subject to governmental control.\n\nThis webinar accompanies the publication of Spark Magazine’s upcoming series\, “History in a Time of Forgetting\,” which grapples with what it means to engage in and uplift historical research amid the present national climate. The online webinar will feature series curators Jennifer Brady and Camron Michael Amin\, from the University of Michigan's Inclusive History Project\, in conversation with series contributors Elisa Alfonso\, David Porter\, S. Shani Saunders\, and Tenisha Tevis. These writers take a range of approaches to history and remembering\, exploring pop culture analysis\, community storykeeping\, personal history\, and public pedagogy.
UID:152624-21914195@events.umich.edu
URL:https://events.umich.edu/event/152624
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:AEM Featured
LOCATION:Off Campus Location
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260917T154656
DTSTART;TZID=America/Detroit:20261020T160000
DTEND;TZID=America/Detroit:20261020T171500
SUMMARY:Workshop / Seminar:Mechanistic Insights into Metal-Protein Interactions: Implications for Neurodegenerative Disease Progression and Intervention
DESCRIPTION:Elevated levels of protein expression and aberrant metal exposure have been reported in many neurodegenerative diseases\, including Huntington’s Disease (HD). While there is currently no cure for HD\, metal chelation therapies have been shown to assuage disease symptoms including chorea. These observations underscore the critical need to understand how metal-protein interactions are involved in disease pathogenesis. Our objective in this work is to elucidate the role of copper (Cu) and other biorelevant metals in HD and\, more specifically\, their interactions with the huntingtin protein (htt). We aimed to characterize the Cu-htt interaction and speciation trends in our in vitro HD system\, as well as the influence of disease-relevant Cu concentrations on protein oligomerization/aggregation both in vitro and in vivo. We utilized multiple spectroscopic techniques (circular dichroism\, electron paramagnetic resonance\, UV-Vis absorption\, dynamic light scattering\, and mass spectrometry) that cover a broad range of energy scales\, allowing us to characterize protein structure at the molecular\, secondary structure\, and quaternary structure levels. Additionally\, site-directed mutagenesis of several putative metal binding residues was used to define the roles of specific amino acids in mediating oligomerization/aggregation\, metal binding\, and redox chemistry. Taken together\, our work has led to the first report of multiple copper binding sites in non-pathological htt and provides insight into one pathway for depletion of native htt pools that may contribute to HD.
UID:151930-21912476@events.umich.edu
URL:https://events.umich.edu/event/151930
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Chemistry,Inorganic Chemistry
LOCATION:Chemistry Dow Lab - CHEM 1640
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T182158
DTSTART;TZID=America/Detroit:20261020T170000
DTEND;TZID=America/Detroit:20261020T190000
SUMMARY:Workshop / Seminar:U-M Global StorySLAM!
DESCRIPTION:Join us for a special evening as members of the U-M community share personal stories of living\, learning\, and growing in new places—whether that’s studying abroad or navigating life as an international student in the U.S. Hear candid accounts of funny\, moving\, eye-opening\, and transformative moments that shape our global journeys\, both near and far. Celebrate cultural insights\, new perspectives\, and the power of storytelling with our international community.Light refreshments provided. All are welcome!\nThis event is organized by the Center for Global & Intercultural Study\, Global Engagement — Office of the Provost\, the International Institute\, International Programs in Engineering\, Ross Global Initiatives\, and the International Center.
UID:150961-21910632@events.umich.edu
URL:https://events.umich.edu/event/150961
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Sessions
LOCATION:North Quad, Space 2435
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260922T182138
DTSTART;TZID=America/Detroit:20261020T180000
DTEND;TZID=America/Detroit:20261020T190000
SUMMARY:Workshop / Seminar:Wolverine Village Building 4 (2026-2027) (Housing)
DESCRIPTION:
UID:150216-21913611@events.umich.edu
URL:https://events.umich.edu/event/150216
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Sessions
LOCATION:Lounge 1200
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20260813T102754
DTSTART;TZID=America/Detroit:20261020T190000
DTEND;TZID=America/Detroit:20261020T210000
SUMMARY:Social / Informal Gathering:Game Nights at The Connector
DESCRIPTION:Do you like board games? Card games? Do you like free popcorn? We welcome all types of players here! Every Tuesday\, the Connector Community Assistants are hosting a game night where we eat delicious popcorn and have a chill (or competitive\, if that’s your energy!) night of joy and connection with one another! Bring your friends and hang! \n\nThe Connector is located in West Quad.
UID:150142-21908197@events.umich.edu
URL:https://events.umich.edu/event/150142
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Community Building,Community Engagement,Community Gathering,Free,Housing,Welcome Week,Welcome Week Event,Welcome26
LOCATION:The Connector
CONTACT:
END:VEVENT
END:VCALENDAR