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DTSTART:20070311T020000
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BEGIN:VEVENT
DTSTAMP:20250220T063254
DTSTART;TZID=America/Detroit:20250224T153000
DTEND;TZID=America/Detroit:20250224T163000
SUMMARY:Workshop / Seminar:Biomedical Engineering Seminar Series
DESCRIPTION:Designer Proteins for Cell Signaling\nAbstract:\nOver the years\, I worked on designing ‘brand new’ (de novo) protein complexes—ordered and disordered—using computational tools such as Rosetta. I created large symmetric protein assemblies through the rigid helical fusion of smaller protein chains and later expanded this approach to design disordered system-wide protein networks with unique mechano-fluidic properties inside and outside of cells. Using these de novo protein complexes\, I developed a soluble agonist for Notch signaling\, a key pathway in cell development and immune function.\n\nDesigning a ‘cytokine-like’ soluble Notch agonist has been a long-standing challenge because Notch signaling typically requires direct cell-cell contact and mechanical pulling. After successfully designing this agonist\, I uncovered its mechanism of action and applied it in T cell development from hematopoietic stem cells in a bioreactor\, advancing cell-based therapies. The agonist also boosted T cell function in vivo by expanding antigen-specific T cells during vaccination and promoting antibody class switching\, demonstrating significant promise as an immunotherapy.\n\nIn my future lab\, I will use computational tools to design complex heteromeric protein assemblies rarely found in nature. I aim to explore their vast potential in controlling cellular signaling\, particularly in immune and stem cells\, to develop innovative therapies.
UID:132935-21872098@events.umich.edu
URL:https://events.umich.edu/event/132935
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Basic Science,Biointerfaces,Biology,biomedical,biomedical engineering,Bioninterfaces,Biosciences,Biotechnology,bme,engineer,engineering,Medicine,Michigan Engineering
LOCATION:Lurie Biomedical Engineering (formerly ATL) - 1170
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20250224T142039
DTSTART;TZID=America/Detroit:20250224T153000
DTEND;TZID=America/Detroit:20250224T170000
SUMMARY:Workshop / Seminar:We’re Biased\, So Now What? Personalizing and Mitigating Unconscious Bias
DESCRIPTION:Many of us are committed to diversity\, equity\, and inclusion and accept the extensive evidence from scholarly studies in psychology and neuroscience demonstrating that we all have unconscious biases that affect our interactions with others. The question then becomes\, how do we not only become aware of our biases\, but also work to overcome them?\nLearning Objectives:Gain knowledge of societal biases and self-awareness of one's unconscious biasesDevelop strategies to advocate for inclusion in light of unconscious bias\nThis workshop fulfills the unconscious bias requirement for Rackham’s DEI certificate program.\nThis workshop is designed for University of Michigan master's students\, doctoral students\, and postdoctoral fellows. For faculty and staff\, please contact rackhampdeworkshops@umich.edu to see if we can accommodate your attendance.
UID:130198-21865584@events.umich.edu
URL:https://events.umich.edu/event/130198
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Sessions
LOCATION:Virtual via Zoom
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20241219T181547
DTSTART;TZID=America/Detroit:20250224T153000
DTEND;TZID=America/Detroit:20250224T170000
SUMMARY:Workshop / Seminar:We’re Biased\, So Now What? Personalizing and Mitigating Unconscious Bias
DESCRIPTION:\nMany of us are committed to diversity\, equity\, and inclusion and accept the extensive evidence from scholarly studies in psychology and neuroscience demonstrating that we all have unconscious biases that affect our interactions with others. The question then becomes\, how do we not only become aware of our biases\, but also work to overcome them?\nLearning Objectives:\n\nGain knowledge of societal biases and self-awareness of one’s unconscious biases\nDevelop strategies to advocate for inclusion in light of unconscious bias\n\nThis workshop fulfills the unconscious bias requirement for Rackham’s DEI certificate program.\nThis workshop is designed for University of Michigan master’s students\, doctoral students\, and postdoctoral fellows. For faculty and staff\, please contact rackhampdeworkshops@umich.edu to see if we can accommodate your attendance.\nRegistration is required at https://myumi.ch/qVeM4.\n\nWe want to ensure full and equitable participation in our events. If an accommodation would promote your full participation in this event\, please follow the registration link to indicate your accommodation requirements. Please let us know as soon as possible in order to have adequate time\, preferably one week\, to arrange for your requested accommodations or an effective alternative.
UID:130216-21865604@events.umich.edu
URL:https://events.umich.edu/event/130216
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Diversity,Graduate Students
LOCATION:Off Campus Location
CONTACT:
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