BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//UM//UM*Events//EN
CALSCALE:GREGORIAN
BEGIN:VTIMEZONE
TZID:America/Detroit
TZURL:http://tzurl.org/zoneinfo/America/Detroit
X-LIC-LOCATION:America/Detroit
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20070311T020000
RRULE:FREQ=YEARLY;BYMONTH=3;BYDAY=2SU
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20071104T020000
RRULE:FREQ=YEARLY;BYMONTH=11;BYDAY=1SU
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTAMP:20231126T080922
DTSTART;TZID=America/Detroit:20231201T120000
DTEND;TZID=America/Detroit:20231201T130000
SUMMARY:Workshop / Seminar:LAGS Seminar | Seizing Opportunities - From Michigan to Congo
DESCRIPTION:Zoom:\nhttps://umich.zoom.us/j/95573161835\nMeeting ID: 955 7316 1835\nPasscode: 054136\n\nUpon finishing my PhD in CME at Michigan\, my wife and I moved to The Democratic Republic of Congo (DRC)\, located in central sub-Saharan Africa\, where I’ve been teaching undergraduate math and physics since 2018. The DRC is a challenging place for physics education. The poor quality of primary and secondary education along with chronic poverty and insecurity means that students are often ill prepared for university physics. However\, there is still a need for qualified STEM practitioners to solve the many technical challenges of a growing society. The experience of teaching in the DRC has changed me forever. In this seminar\, I will share with you some of the challenges I faced and the rewards I received by seizing this unique opportunity.
UID:115426-21834659@events.umich.edu
URL:https://events.umich.edu/event/115426
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Physics,Science
LOCATION:West Hall - 335
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20231201T112028
DTSTART;TZID=America/Detroit:20231201T120000
DTEND;TZID=America/Detroit:20231201T140000
SUMMARY:Conference / Symposium:Marsal School dije Office
DESCRIPTION:
UID:102119-21824378@events.umich.edu
URL:https://events.umich.edu/event/102119
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Sessions
LOCATION:Virtual via Zoom
CONTACT:
END:VEVENT
BEGIN:VEVENT
DTSTAMP:20231120T134314
DTSTART;TZID=America/Detroit:20231201T120000
DTEND;TZID=America/Detroit:20231201T130000
SUMMARY:Workshop / Seminar:Metal Homeostasis at the host – pathogen interface: from nutritional immunity to nutritional intoxication
DESCRIPTION:Antibiotic resistance is a global health concern that causes over one million deaths worldwide. Understanding molecular mechanisms of bacterial pathogenesis and the innate immune response is critical for identifying new antimicrobial therapeutic approaches. My lab is interested in characterizing the underlying determinants of metal homeostasis with an eye toward creating new antimicrobial agents. One-third of the proteome is predicted to comprise metalloproteins. Metals are essential for all forms of life as they serve as enzymatic cofactors\, structural stabilizers and chemical messengers. However\, high concentrations of metals are toxic. Thus\, maintenance of metal homeostasis is essential at the host-pathogen interface. For example\, S100A12 is a high affinity transition metal binding protein that starves invading pathogens and prevents them from acquiring essential zinc\, in a process termed nutritional immunity. I will present recent results from my lab that sugges t zinc binding to S100A12 potentiates oligomerization and is associated with activation of inflammation through the receptor for advanced glycation end products. The importance of zinc regulation is also highlighted in the pathogenesis of the human pathogen Streptococcus agalactiae\, one of the primary causes of adverse pregnancy outcomes. CadD\, a metal efflux transporter is essential for S. agalactiae to resist zinc intoxication by macrophages\, thereby facilitating ascending infection in a pregnant host. Together\, these data demonstrate the importance of understanding metal homeostasis and provide potential pathways to overcoming antibiotic resistance.
UID:109096-21821065@events.umich.edu
URL:https://events.umich.edu/event/109096
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biophysics,seminar
LOCATION:Chemistry Dow Lab - 1400
CONTACT:
END:VEVENT
END:VCALENDAR