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DTSTART:20070311T020000
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BEGIN:VEVENT
DTSTAMP:20250117T160054
DTSTART;TZID=America/Detroit:20250131T120000
DTEND;TZID=America/Detroit:20250131T130000
SUMMARY:Workshop / Seminar:Uncovering the molecular interactions underlying MBD protein Liquid-liquid Phase Separation
DESCRIPTION:Chromatin organization controls DNA’s accessibility to regulatory factors to influence gene expression. Heterochromatin\, or transcriptionally silent chromatin enriched in methylated DNA and methylated histone tails\, self-assembles through multivalent interactions with its associated proteins into a condensed\, but dynamic state. Liquid-liquid phase separation (LLPS) of key heterochromatin regulators\, such as heterochromatin protein 1 (HP1)\, plays an essential role in heterochromatin assembly and function. Methyl-CpG-binding protein 2 (MeCP2)\, the most studied member of the methyl-CpG-binding domain (MBD) family of proteins\, has been recently shown to undergo LLPS in the absence and presence of methylated DNA. These studies provide a new mechanistic framework for understanding the role of methylated DNA and its readers in heterochromatin formation. However\, the details of the molecular interactions by which other MBD family members undergo LLPS to mediate genome organization and transcriptional regulation are not fully understood. Here\, we focus on two MBD proteins\, MBD2 and MBD3\, that have distinct but interdependent roles in gene regulation. Using an integrated computational and experimental approach\, we uncover the homotypic and heterotypic interactions governing MBD2 and MBD3 phase separation and DNA’s influence on this process. We show that despite sharing the highest sequence identity and structural homology among all the MBD protein family members\, MBD2 and MBD3 exhibit differing residue patterns resulting in distinct phase separation mechanisms. Understanding the molecular underpinnings of MBD protein condensation offers insights into the higher-order\, LLPS-mediated organization of heterochromatin.
UID:125332-21854752@events.umich.edu
URL:https://events.umich.edu/event/125332
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Biophysics
LOCATION:Chemistry Dow Lab - 1640
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20250207T161055
DTSTART;TZID=America/Detroit:20250131T123000
DTEND;TZID=America/Detroit:20250131T130000
SUMMARY:Tours:Coral Reef Tank Visit
DESCRIPTION:Join Professor Jim Bardwell for a peek behind the scenes at his large coral reef tank featuring many species of coral\, anemone\, and fish. Explore reef ecology and\, if you're lucky\, get a glimpse of a reclusive octopus!  30 minutes\, limit 12 people. This program takes place in the research area of the Biological Sciences Building and is recommended for ages 6 and up.\nSpace is available first come\, first served. Sign up and meet at the Welcome desk.
UID:125537-21864685@events.umich.edu
URL:https://events.umich.edu/event/125537
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Museum,natural history museum
LOCATION:Museum of Natural History - Welcome Desk
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20250114T152917
DTSTART;TZID=America/Detroit:20250131T130000
DTEND;TZID=America/Detroit:20250131T160000
SUMMARY:Careers / Jobs:2025 Green Career Fair
DESCRIPTION:Looking for an internship\, job\, or networking opportunities? Save the date for the On-Campus Green Career Fair\, hosted by the School for Environment & Sustainability. Find more information here (https://seas.umich.edu/student-services/career-services/green-career-fair). \n\nParticipating employers are hiring specifically for environmental and sustainability focused positions. All University of Michigan students are welcome to attend\, regardless of your degree. Registration is not required\, but your U-M ID is required for entry. If the Green Career Fair overlaps with your classes\, consider asking your professor if you can attend the fair and make up your work for that day.\n\nIf you have any questions\, please email seas-careers@umich.edu.
UID:131167-21867873@events.umich.edu
URL:https://events.umich.edu/event/131167
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Career
LOCATION:Michigan League - Ballroom (2nd Floor)
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20250215T123154
DTSTART;TZID=America/Detroit:20250131T130000
DTEND;TZID=America/Detroit:20250131T134500
SUMMARY:Careers / Jobs:Explore Deloitte: Recruiting Workshop (Option 1)
DESCRIPTION:Recruiting Workshop: About Deloitte + Recruiting TipsJoin Deloitte recruiters for a Deloitte overview\, plus tips and tricks to prepare for recruiting with us!During this session we’ll go in-depth on who we are\, what we offer\, and what sets Deloitte apart. We'll also dive into mastering recruiting etiquette. Learn how to network effectively\, prepare for virtual interviews\, and communicate professionally. This session will equip you with essential skills to enhance your job search and make a lasting impression with Deloitte. Don't missthis opportunity to elevate your professional presence! Regardless of your major or preferred business\, this session will provide a general overview of the campus recruiting process at Deloitte.This event will be in held via Zoom webinar Friday\, January 31st from 1:00pm - 1:45pm ET  and will not require video participation by attendees. Final Zoom details will be sent to registrants as the date approaches.
UID:131814-21869281@events.umich.edu
URL:https://events.umich.edu/event/131814
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:
LOCATION:
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20250131T122050
DTSTART;TZID=America/Detroit:20250131T130000
DTEND;TZID=America/Detroit:20250131T143000
SUMMARY:Workshop / Seminar:IGR/Marsal Ed Studies Grad Students 1/31/25 (CommonGround)
DESCRIPTION:
UID:131998-21869622@events.umich.edu
URL:https://events.umich.edu/event/131998
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Sessions
LOCATION:
CONTACT:
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