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DTSTAMP:20240827T110923
DTSTART;TZID=America/Detroit:20240910T160000
DTEND;TZID=America/Detroit:20240910T171500
SUMMARY:Workshop / Seminar:Utilizing Biocatalysis and Synthetic Chemistry to Access New Natural Products
DESCRIPTION:Natural products (NPs) are a bountiful source of bioactive molecules. Bioinformatics data suggest hundreds-of-thousands of novel NPs remain to be discovered.  Unfortunately\, many NPs are not produced under standard laboratory conditions. We are developing methods to access NPs from cryptic biosynthetic gene clusters (BGCs) utilizing a combination of bioinformatics\, synthetic chemistry\, and biocatalysis. Specifically\, we are focused in two areas: cyclic peptides and γ-butyrolactone (GBL) hormones. For cyclic peptides\, we recently developed SNaPP (Synthetic Natural Product Inspired Cyclic Peptides). SNaPP expedites bioactive molecule discovery by combining bioinformatics predictions of non-ribosomal peptide synthetases with chemical synthesis of the predicted natural products. SNaPP enabled us to discover several bioactive cyclic peptides. However\, it also opened our eyes to the challenge of synthesizing small cyclic peptides. Using the results from SNaPP\, we identified a PBP-like cyclase capable of performing challenging cyclizations\, such as for tetrapeptides with a greatly expanded substrate scope that could have great utility as a biocatalyst. For GBLs\, these molecules have previously been found to induce production of many bioactive NPs. Over half of Streptomyces strains are predicted to have GBL signaling pathways. Unfortunately\, only a few GBLs and their cognate repressors are known because 1) GBLs are produced at very low quantities and 2) no rapid\, efficient assays exist to identify them. We bioinformatically predicted previously uncharacterized GBL receptors that we predict bind to known GBLs or close derivatives. We have developed synthetic and biocatalytic methods to access GBLs and derivatives in fewer steps and improved stereoselectivies. Finally\, we have developed GFP-based assays that allow rapid identification of active hormones. This information will allow us to further explore the addition of exogenous hormones as a method to induce production of cryptic biosynthetic gene clusters.
UID:109309-21821374@events.umich.edu
URL:https://events.umich.edu/event/109309
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Chemistry,Chemical Biology
LOCATION:Chemistry Dow Lab - 1640
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20240826T151618
DTSTART;TZID=America/Detroit:20240910T160000
DTEND;TZID=America/Detroit:20240910T170000
SUMMARY:Workshop / Seminar:Ziwet Lecture I: Lorentzian Polynomials\, Matroids over Hyperfields\, and Related Topics
DESCRIPTION:Lorentzian polynomials serve as a bridge between continuous and discrete convex analysis\, with tropical geometry providing the critical link. The tropical connection is used to produce Lorentzian polynomials from discrete convex functions\, leading for example to a short proof of Mason's conjecture on the number of independent sets of a matroid. This lecture series will explore the intricate relationships among Grassmannians over hyperfields\, dequantization processes\, and the theory of Lorentzian polynomials. In ongoing collaborative work with Matt Baker\, Mario Kummer\, and Oliver Lorscheid\, we extend the connection between Lorentzian polynomials and discrete convex functions to matroids over triangular hyperfields\, as introduced by Viro. This extension deepens our understanding of the space of Lorentzian polynomials\, revealing a complex interplay among analysis\, combinatorics\, and geometry.\n\nThe three lectures in this series are designed to be accessible to a broad audience and appropriate for a Department Colloquium.\n\nAmong his many honors\, Prof. Huh is a recipient of the Fields Medal (2022)\, the MacArthur Fellowship (2022)\, and the New Horizons in Mathematics Prize (2019). He received his PhD in Mathematics from U-M in 2014.
UID:120328-21844574@events.umich.edu
URL:https://events.umich.edu/event/120328
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Mathematics,AEM Featured
LOCATION:East Hall - 1360
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20240925T123320
DTSTART;TZID=America/Detroit:20240910T163000
DTEND;TZID=America/Detroit:20240910T173000
SUMMARY:Careers / Jobs:Administrative Fellowship Webinar
DESCRIPTION:The administrative fellowship offers an unparalleled opportunity to work side-by-side with senior leaders\, gain immersive hands-on experience\, and drive critical\, large-scale projects. Join an upcoming webinar to learn more!September 10\, 4:30 - 5:30PMSeptember 16\, 5:00 - 6:00PM
UID:125274-21854634@events.umich.edu
URL:https://events.umich.edu/event/125274
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:
LOCATION:
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20240619T094628
DTSTART;TZID=America/Detroit:20240910T163000
DTEND;TZID=America/Detroit:20240910T173000
SUMMARY:Presentation:Sanger Leadership Center Info Session
DESCRIPTION:LEARN TO LEAD AND REFLECT THIS YEAR!\n\nJoin our staff and student leaders to learn which opportunities you can get involved in this year at the Sanger Leadership Center to advance your leadership skills and deepen your personal growth. Whether you end up in the boardroom at Michigan Stadium\, on a personal journey to learn about your values and purpose\, or with a group of like-minded peers practicing the art of storytelling\, all of our programs are designed to help you learn through action and reflection.\n\nSANGER LEADERSHIP CENTER INFO SESSION\nTUESDAY\, SEPTEMBER 10\, 2024 | 4:30-5:30 PM\n\nBlau Colloquium (5th Floor Blau Hall)\nat the Ross School of Business\n700 East University Avenue\nNo RSVP necessary.\n\nYou'll have the opportunity to:\n• Meet with Sanger staff and current students\n• Learn which programs are right for you\n• Mingle with other students from Ross and across U-M\n• Enter to win Sanger swag\n• Enjoy snacks\n\nWe’ll feature the following programs:\n• Leading Inclusive Teams\n• Leadership Crisis Challenge\n• Leadership Dialogues\n• Legacy Lab\n• Michigan Ross Leader Endorsement\n• Ross Leaders Academy\n• Story Lab\n\nQuestions? Contact us at rossleaders@umich.edu.
UID:122880-21849743@events.umich.edu
URL:https://events.umich.edu/event/122880
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Undergraduate Students,Undergraduate,Leadership,Graduate Students,Graduate,Free,Career,Business
LOCATION:Ross School of Business - Blau Colloquium
CONTACT:
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DTSTAMP:20240515T155253
DTSTART;TZID=America/Detroit:20240910T163000
DTEND;TZID=America/Detroit:20240910T180000
SUMMARY:Lecture / Discussion:Wallenberg Medal and Lecture | Nnimmo Bassey\, Environmental Leader\, Architect\, Poet
DESCRIPTION:Full details on the Wallenberg website: https://myumi.ch/kZdE2\n\nNnimmo Bassey\, executive director of the Health of Mother Earth Foundation and a global environmental activist\, will receive the 2024 Wallenberg Medal from the University of Michigan on Tuesday\, September 10th in Ann Arbor.\n\nNnimmo Bassey is an architect and director of the Nigeria-based ecological think-tank\, Health of Mother Earth Foundation (HOMEF) and member of the steering committee of Oilwatch International\, a network resisting the expansion of fossil fuel extraction in the Global South. He chaired Friends of the Earth International (2008-2012)\, was a co-recipient of the 2010 Right Livelihood Award\, also known as the “Alternative Nobel Prize\,” and received the Rafto Human Rights Prize in 2012. Bassey has received honorary doctorate degrees from University of York (UK) in 2019 and from York University (Canada) in 2023. Bassey’s books include *To Cook a Continent: Destructive Extraction* and *The Climate Crisis in Africa and Oil Politics: Echoes of Ecological War*. His poetry collections include: *We Thought It Was Oil But It Was Blood* (1998)\, *I Will Not Dance to Your Beat* (2010)\, and *I See the Invisible* (2024). \n\n“As an architect\, poet\, writer\, and human rights advocate\, Nnimmo Bassey works to address root cause issues driving climate migration\, environmental and social impacts of extractive production\, and hunger in the Niger Delta. His commitment to socio-ecological justice connects large-scale issues of climate change\, exploitation of natural resources\, and political/corporate intransigence to the lives of individuals in the Niger Delta and beyond\,” said Sioban Harlow\, Professor Emerita of Epidemiology and Global Public Health and chair of the Wallenberg Medal Executive Committee. “Just as Raoul Wallenberg trained as an architect at the University of Michigan before bringing his multifaceted skills to humanitarian work\, Bassey’s background as an architect undergirds his environmental leadership.”\n\n______________________________\n\nThe Wallenberg Medal and Lecture honors the legacy of Raoul Wallenberg who graduated from U-M’s College of Architecture in 1935 and saved the lives of tens of thousands of Hungarian Jews near the end of World War II. In 1944\, at the request of Jewish organizations and the American War Refugee Board\, the Swedish Foreign Ministry sent Wallenberg on a rescue mission to Budapest. Over the course of six months\, Wallenberg issued thousands of protective passports and placed many thousands of Jews in safe houses throughout the besieged city. He confronted Hungarian and German forces to secure the release of Jews\, whom he claimed were under Swedish protection\, and saved more than 80\,000 lives.\n\nAdministered by the University’s Donia Human Rights Center\, U-M awards the Wallenberg Medal to those who\, through their actions and personal commitment\, perpetuate Wallenberg’s extraordinary accomplishments and human values\, and demonstrate the capacity of the human spirit to stand up for the helpless\, to defend the integrity of the powerless\, and to speak out on behalf of the voiceless.\n\nThe Wallenberg Medal and Lecture ceremony is free and open to the public. Tickets are not required. Please direct any inquiries about the event and requests for event accommodations to wallenberglecture@umich.edu or 734-936-3973.
UID:116533-21837366@events.umich.edu
URL:https://events.umich.edu/event/116533
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Environment,Climate Change,human rights,Interdisciplinary,Social Impact,social justice,sustainability
LOCATION:Ross School of Business - Robertson Auditorium
CONTACT:
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DTSTAMP:20240925T123220
DTSTART;TZID=America/Detroit:20240910T170000
DTEND;TZID=America/Detroit:20240910T180000
SUMMARY:Careers / Jobs:DC Investments Virtual Company Presentation
DESCRIPTION:DC Investments Management invites students interested in assisting with the evaluation and development of global investments and trading strategies to attend our virtual company presentation. We will discussthe firm\, our work\, and our culture. This will help you determine whether you are interested in applying to our Analyst/Associate position and ifso\, what the recruiting process looks like.Those who register to attend will receive an email with the Zoom link for the presentation as weget closer to the event.
UID:122213-21848468@events.umich.edu
URL:https://events.umich.edu/event/122213
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:
LOCATION:
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DTSTAMP:20240925T123308
DTSTART;TZID=America/Detroit:20240910T170000
DTEND;TZID=America/Detroit:20240910T180000
SUMMARY:Careers / Jobs:Discover Strats: Fundamentals of the Trading Floor
DESCRIPTION:Join the Morgan Stanley Strats Division and dive deeper into the complex world of our Trading Floor. During this session\, you will learn about our two business lines within Strats (Fixed Income and Institutional Equity) and begin to understand how Strats partner with the Traders day-to-day. This event is for graduate-level students with graduation datebetween December 2025 and Spring 2026. ​Fun Fact: At Morgan Stanley\, we refer to our Quantitative Finance business as our Strats businessdue to their focus on intricate strategy.Event Details:  Date: September 10\, 2024Time: 5:00pm - 6:00pm ESTLocation: Zoom link to be disclosed once registration is confirmedPlease register using this link: Discover Strats: Fundamentals of the Trading Floor - Morgan Stanley Campus 
UID:125154-21854478@events.umich.edu
URL:https://events.umich.edu/event/125154
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:
LOCATION:
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20240905T171229
DTSTART;TZID=America/Detroit:20240910T170000
DTEND;TZID=America/Detroit:20240910T190000
SUMMARY:Workshop / Seminar:How to Flourish: Social Wellness
DESCRIPTION:Workshop Series designed to help first-year students flourish throughout their time at U-M. Rooted in the 8 dimensions of wellness identified in the Wolverine Wellness Wheel. In this session our guest speaker\, Dr. Reggie Walker will facilitate \"The Mask-Off: Showing My True Self\" Workshop.\n\n\"The Mask Off: Showing My True Self\" is an in-depth self-awareness workshop that asks participants to explore the different masks they wear in their daily lives and a means of discovering how these masks have been both helpful and harmful to them\, especially in their relationships with others\, personally and otherwise. The workshop will look at masking on a macro level from a historical standpoint while also looking at how and why individuals specifically choose to mask today.
UID:123720-21851408@events.umich.edu
URL:https://events.umich.edu/event/123720
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Central Campus,Trotter Multicultural Center,Sessions,Multicultural,First-year
LOCATION:Trotter Multicultural Center- Multipurpose Room 1
CONTACT:
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