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DTSTAMP:20260113T150352
DTSTART;TZID=America/Detroit:20260122T093000
DTEND;TZID=America/Detroit:20260122T110000
SUMMARY:Workshop / Seminar:Dissertation Defense Seminar: Suji Ye
DESCRIPTION:Plants rely on a two-tiered immune system\, consisting of pattern-triggered immunity (PTI initiated by cell-surface pattern recognition receptors (PRRs) and effector-triggered immunity (ETI) activated by intracellular NOD-like (NLR) immune receptors. These two types of immunity are essential for protecting plants from pathogen invasion balancing growth and defense to maintain immune homeostasis. \n\nCalcium (Ca2+) is a secondary messenger that plays an essential role in plant immunity by transmitting immune signals from PRR and NLR receptors to downstream immune response upon pathogen perception and regulating processes such as transcriptional reprogramming\, reactive oxygen species production\, and kinase activation. However\, imbalanced Ca2+ signaling can induce autoimmunity\, causing cell death in plants.\n \nWe are interested in how Ca2+ signaling is integrated into a regulatory network that maintains immune homeostasis. In this thesis\, I characterized three closely related cyclic nucleotide-gated ion channels (CNGCs) acting as Ca2+ channels to suppress plant autoimmunity and regulate reproductive development. In Arabidopsis thaliana\, 20 CNGCs are classified into five groups (I\, II\, III\, IVa\, and IVb) based on sequence homology. Structurally\, Arabidopsis CNGCs contain six transmembrane domains\, a P-loop domain for ion selection\, a cyclic nucleotide-binding domain (CNBD)\, and a calmodulin-binding domain (CaMBD) for channel activity regulation. Our lab previously demonstrated that activation of CNGC19 and CNGC20\, upon phosphorylation by the receptor kinase BAK-to-life 2 (BTL2)\, induces massive intracellular Ca2+ influx\, leading to autoimmunity\, due to perturbation of the shared PRR-coreceptors BAK1/SERK4. In addition\, the chimeric CNGC11 and CNGC12\, which likely form an active calcium channel\, also cause autoimmunity. I systematically characterized CNGC11\, CNGC12\, and their closest homolog CNGC3 by generating single\, double\, and triple mutants with CRISPR-Cas gene editing. Importantly\, neither CNGC3\, 11\, nor 12 single or double mutants altered plant growth and immune responses. However\, the cngc3/11/12 triple mutants exhibited growth defects with varying levels of cell death. In addition\, the cngc3 single mutants showed infertility\, with shorter siliques and fewer seeds\, despite normal stamen and pistil structures. Using an Agrobacterium-mediated VIGS (virus-induced gene silencing) approach\, I show that the EDS1(ENHANCED DISEASE SUSCEPTIBILITY 1)-PAD4 (PHYTOALEXIN DEFICIENT 4)-ADR1s (ACTIVATED DISEASE RESISTANCE 1) module\, which plays a central role in toll/interleukin-1 receptor NLR (TNL)-mediated immunity\, is essential for the RNAi-CNGC3/11/12-induced cell death. RNA-sequencing analysis further suggests the involvement of additional Ca2+ channels\, pumps\, and TIR-domain-containing proteins in cngc3/11/12 cell death.  These results suggest that the depletion of CNGC3\, 11\, and 12 activates additional Ca2+ channels\, which further activate the TIR-EDS1-PAD4-ADR1s module to induce cell death. \n\nCeramides are a class of sphingolipids known to induce programmed cell death in plants and animals with unclear mechanisms. Mutation of ceramide kinase ACD5\, which results in the accumulation of high levels of ceramides\, induces spontaneous cell death in plants. Using VIGS\, I found that RNAi-ACD5-induced cell death depends on the NLR SUMM2 and other components of the SUMM2 signaling pathway. In addition\, ceramide levels are elevated in autoimmune mutants when SUMM2 is activated. Furthermore\, ceramides activate the phosphatase activity of Protein Phosphatase 5 (PP5) and promote PP5 interaction with the co-chaperone protein HOP1\, which are essential for SUMM2 activation. Collectively\, our findings reveal a mechanism by which ceramides promote cell death in plants through activation of a phosphatase that subsequently activates NLR immune receptors.\n\nIn summary\, our studies underscore the importance of maintaining balanced Ca2+ signaling and ceramide levels for immune homeostasis in plants.
UID:143855-21894126@events.umich.edu
URL:https://events.umich.edu/event/143855
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Dissertation Defense,Bsbsigns,Biology
LOCATION:Biological Sciences Building - 1010
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20260122T092103
DTSTART;TZID=America/Detroit:20260122T100000
DTEND;TZID=America/Detroit:20260226T113000
SUMMARY:Workshop / Seminar:Creating Cultures of Belonging in Practice - Staff Class | Winter 2026
DESCRIPTION:Course Description: Hosted by Michigan Housing’s Community Connections and Engagement Department\, this dialogue series is offered to new and seasoned Student Life staff as a professional development opportunity. The series emphasizes reflection\, connection\, and intentional practice to support a culture of belonging. \n\nOver 6 weeks\, participants are guided from self-awareness to action through three modules:Inclusion on Purpose: Self reflection and inclusive practices skill-buildingStrengthening Communities: Recognizing barriers to access and belongingBelonging in Action: Applying inclusive principles in everyday work\nLearning Outcomes: At the conclusion of the series\, participants will be able to –Implement inclusive strategies in leadership\, supervision\, collaboration\, and interactions with students and colleagues.Cultivate relationship-building skills that enhance connection and a sense of belonging within the diverse University of Michigan community.Assess policies\, practices\, and office operations through an inclusive perspective.
UID:142167-21890152@events.umich.edu
URL:https://events.umich.edu/event/142167
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Sessions
LOCATION:Asubuhi Multicultural Lounge - West Quad, room 1031
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20251212T090011
DTSTART;TZID=America/Detroit:20260122T100000
DTEND;TZID=America/Detroit:20260122T160000
SUMMARY:Exhibition:GalleryDAAS Presents: Archives of Resistance: Visuals and Voices from Carceral State Project Research
DESCRIPTION:Opening December 8\, 2025 and running through January 2026\nGalleryDAAS| Haven Hall| G648| Monday - Friday 10-4pm\n\nThis exhibit showcases stories of resistance\, resilience\, and hope\, in the face of mass incarceration\, police violence\, immigrant detention\, and systematic racial criminalization. Archives of Resistance presents art\, prisoner correspondence\, research publications\, and archival documentation produced by the component projects of the Carceral State Project. These include: The Reckoning Project\, Immigrant Justice Lab\, Black & Pink at SPH\, ICE in the Heartland\, Critical Carceral Visualities\, Policing & Social Justice HistoryLab\, and Confronting Conditions of Confinement and Resistance. Artwork made by people in prison through Prison Creative Arts Project workshops is also on display. \n\nThe U-M Carceral State Project\, housed within the Department of Afroamerican and African Studies\, brings impacted communities and advocacy organizations together with researchers from the University of Michigan. The CSP was first organized in 2018 and has since grown to involve over a dozen community and campus partners\, many graduate students\, and more than 400 undergraduate researchers. \n\nThrough public scholarship\, creative expression\, multimedia storytelling\, and archival documentation\, we highlight the lived experiences and persistent resistance of those impacted by criminalization\, policing\, incarceration\, immigrant detention\, and other forms of carceral control in the state of Michigan and beyond. The work presented in this exhibit represents only a sliver of the extensive research\, art\, advocacy\, public engagement\, and other products generated by the Carceral State Project over the years.
UID:142351-21890698@events.umich.edu
URL:https://events.umich.edu/event/142351
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Art,History,african and afroamerican studies,Activism,Racism,Race,Political Science,Local Issues,Law,Exhibition
LOCATION:Haven Hall - GalleryDAAS, G648
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20260122T092103
DTSTART;TZID=America/Detroit:20260122T100000
DTEND;TZID=America/Detroit:20260122T120000
SUMMARY:Workshop / Seminar:Mugs & Minors Hot Cocoa Bar
DESCRIPTION:
UID:143103-21892116@events.umich.edu
URL:https://events.umich.edu/event/143103
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Sessions
LOCATION:Mason Hall, G325
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20260113T150644
DTSTART;TZID=America/Detroit:20260122T100000
DTEND;TZID=America/Detroit:20260122T120000
SUMMARY:Social / Informal Gathering:Mugs & Minors Hot Cocoa Bar
DESCRIPTION:All declared DSI Minors are invited to join us for a Hot Cocoa Bar! Enjoy a custom DSI coffee mug\, hot cocoa\, and a variety of toppings. Dairy free hot chocolate and tea will also be available. RSVPs are encouraged! RSVP Here: https://myumi.ch/9p7jA
UID:143835-21894105@events.umich.edu
URL:https://events.umich.edu/event/143835
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Undergraduate Students,Undergraduate,Dsi Minors,Digital Studies Institute
LOCATION:Mason Hall - G325
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20260219T141559
DTSTART;TZID=America/Detroit:20260122T100000
DTEND;TZID=America/Detroit:20260122T120000
SUMMARY:Workshop / Seminar:Practice Behavior-Based Interviewing Using Virtual Reality
DESCRIPTION:Course details and registration are available on the Organizational Learning website.
UID:143106-21892128@events.umich.edu
URL:https://events.umich.edu/event/143106
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Human Resources,Professional Development,Communication
LOCATION:Boyer Building - Conference Room
CONTACT:
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DTSTAMP:20251219T095344
DTSTART;TZID=America/Detroit:20260122T100000
DTEND;TZID=America/Detroit:20260122T103000
SUMMARY:Meeting:U-M Green Team Coffee Chats Winter Semester 2026
DESCRIPTION:Come with your questions\, experiences\, and ideas to help us build a community of practice around sustainable workplaces at U-M! This monthly informal chat is open to all staff who are interested in workplace sustainability. Chats are held over Zoom\, so grab your favorite hot beverage and log in. We share successes\, mishaps\, and learning experiences as well as new opportunities and resources. (In order to encourage candid conversation\, these meetings are not recorded.)
UID:142965-21891853@events.umich.edu
URL:https://events.umich.edu/event/142965
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Sustainability
LOCATION:Off Campus Location
CONTACT:
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BEGIN:VEVENT
DTSTAMP:20251201T121639
DTSTART;TZID=America/Detroit:20260122T103000
DTEND;TZID=America/Detroit:20260122T123000
SUMMARY:Class / Instruction:Michelle Cann Piano Master Class
DESCRIPTION:Michelle Cann\, Professor of Piano at the Curtis Institute of Music\, will teach talented students from the SMTD in a public master class setting. Generously sponsored by the Sally Fleming Master Class Fund.\n\nABOUT THE GUEST ARTIST\n\nLauded as “exquisite” by *The Philadelphia Inquirer* and “a pianist of sterling artistry” by *Gramophone*\, GRAMMY Award winning pianist MICHELLE CANN is one of the most sought-after artists of her generation. Recent engagements include appearances with Chicago Symphony Orchestra\, The Cleveland Orchestra\, The Philadelphia Orchestra\, Los Angeles Philharmonic\, National Symphony Orchestra\, and Orquestra Sinfônica Municipal de São Paulo. She is a recipient of the Sphinx Medal of Excellence and the Andrew Wolf Chamber Music Award\, and she served as the inaugural Christel DeHaan Artistic Partner of the American Piano Awards.\n\nHighlights of Cann’s 2025-26 season include appearances with the Colorado Symphony\, New Jersey Symphony\, Kansas City Symphony\, and Ireland’s National Symphony Orchestra. She also performs the world premiere of a new piano concerto by Valerie Coleman with the National Symphony Orchestra in Washington\, D.C. Her recital appearances include Stanford Live\, Music Toronto\, Chamber Music Detroit\, the Isabella Stewart Gardner Museum\, Spivey Hall\, and a recital tour in China.\n\nRecognized as a leading interpreter of the piano music of Florence Price\, Cann performed the New York City premiere of Price’s *Piano Concerto in One Movement* with The Dream Unfinished Orchestra in July 2016 and the Philadelphia premiere with The Philadelphia Orchestra and Music Director Yannick Nézet-Séguin in February 2021. Her recording of the concerto with the New York Youth Symphony won a GRAMMY Award in 2023 for Best Orchestral Performance. She won a GRAMMY Award in 2025 for *Beyond the Years: Unpublished Songs of Florence Price*\, recorded with soprano Karen Slack\, which features 19 unpublished songs composed by Price. Her acclaimed debut solo album *Revival*\, featuring music by Price and Margaret Bonds\, was released in May 2023 on the Curtis Studio label. She has also recorded two Price piano quintets with the Catalyst Quartet as a part of the quartet’s UNCOVERED series. A champion of emerging talent\, Cann and cellist Tommy Mesa recorded *Our Stories*\, an album of new works by five living composers of color\, which was released in November 2023.\n\nA celebrated chamber musician\, Cann has collaborated with leading artists including the Catalyst\, Dover\, and Juilliard string quartets\, Imani Winds\, violinists Timothy and Nikki Chooi\, soprano Karen Slack\, and mezzo-soprano J’Nai Bridges. She regularly performs duo piano repertoire with her sister\, pianist Kimberly Cann\, as the Cann Duo. She has appeared as co-host and collaborative pianist with NPR’s *From The Top*\, collaborating with actor/conductor Damon Gupton\, violinist Leila Josefowicz\, and violinist and MacArthur Fellow Vijay Gupta. Cann’s numerous media appearances include *Performance Today*\, PBS Great Performances’ *Now Hear This*\, and *Living the Classical Life*.\n\nEmbracing a dual role as performer and pedagogue\, Cann is frequently invited to teach master classes\, give lecture-demonstrations\, and lead teaching residencies. Recent residencies include the Gilmore International Keyboard Festival and the National Conference of the Music Teachers National Association. She has recorded lessons for tonebase\, the popular piano lesson platform. She has also served on the juries of the Cleveland International Piano Competition\, the Kauffman Music Center International Youth Piano Competition\, and the piano competition of the Music Academy of the West.\n\nCann holds bachelor’s and master’s degrees in piano performance from the Cleveland Institute of Music\, where she studied with Paul Schenly and Dr. Daniel Shapiro\, and an Artist’s Diploma from Curtis Institute of Music\, where she studied with Robert McDonald. She joined the Curtis piano faculty in 2020 as the inaugural Eleanor Sokoloff Chair in Piano Studies. She is also on the piano faculty of the Manhattan School of Music.
UID:139266-21885210@events.umich.edu
URL:https://events.umich.edu/event/139266
CLASS:PUBLIC
STATUS:CONFIRMED
CATEGORIES:Workshop,Free,Talk,North Campus,Music
LOCATION:Earl V. Moore Building - Britton Recital Hall
CONTACT:
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