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In this talk, we'll explore how recent improvements in accuracy, throughput, and targeted enrichment now allow us to phase variants, resolve repetitive loci, and detect epigenetic modifications\u2014often in the same molecule. These methods enable analysis of allele-specific methylation, chromatin accessibility, and protein-DNA interactions, even in challenging regions like centromeres or BRCA1. We'll also cover how these techniques apply to spatial and single-cell transcriptomics, empowering nuanced studies in neuroscience and cancer. Altogether, this work moves us closer to a future where multiomic profiling at single-molecule resolution becomes routine\u2014at the bench, not just the core.\r\n\r\nShort Bio\r\n\r\nWinston Timp, an associate professor of biomedical engineering, focuses on the development and application of sequencing technologies to gain a deeper understanding of biology and a more accurate set of clinical tools for human disease. 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It also asks visitors to ponder their own attitudes and experiences, and to submit memories and photos of their time working, studying, volunteering or receiving care at U-M's medical campus and beyond. There are also activities for young visitors.\r\n\r\nThe museum is open to the public every Saturday and Sunday from 12 p.m. to 4 p.m.\r\n\r\nFull details about the exhibit, including parking instructions and how to book a free private group tour on a weekday, are available at http:\/\/michmed.org\/museum\r\n\r\nThe museum has an accessible entrance at the rear of the building.", "occurrence_notes":"Park in nearby municipal lots or structures; on-site parking is extremely limited. 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Her research and creative practice reside at the intersection of architecture, climate action and design excellence as tools toward improved ecological and human health. \r\n\r\n11:00 AM \"Impacts of Climate Change on Freshwater: The Important Role of Dissolved Oxygen\"\r\nKevin Rose (Associate Professor and Director of the Darrin Freshwater Institute, Rensselaer Polytechnic Institute)\r\nDr. Kevin Rose leads a research team at Rensselaer Polytechnic Institute in New York. His research spans ecology and biogeochemistry, focusing predominantly on understanding broad-scale patterns and processes in freshwater ecosystems such as lakes and ponds. A goal of his group is to forecast the future state of aquatic ecosystems in a regional to global context, with an emphasis on understanding how freshwater ecosystems are changing in response to factors such as land use and climate change. This interdisciplinary research draws on diverse skills in biology, ecology, biogeochemistry, advanced environmental sensors, and computational modeling. Dr. Rose's research findings have been published in high-impact journals such as Science and Nature and featured in media outlets such as NPR, the Washington Post, Fox News, and Popular Science magazine. \r\n\r\n1:00 PM \"Tiny Carriers, Big Impact: How Bacteria Drive Transmission of Virus and Antibiotic Resistance Gene in Water\"\r\nYun Shen (Assistant Professor, Department of Civil and Environmental Engineering, George Washington University)\r\nDr. Yun Shen's research is addressing critical challenges in the nexus of environment and health. She is investigating the transmission and control of environmental pathogens in water and wastewater. Especially, her work is focusing on pathogens not as isolated particles, but in their clustered forms. Her work explores bacteria-virus complexities, vesicle-associated viruses, plastic-pathogen interactions, in the complex environments. In addition, she examines how bacterial pathogens respond to oxidative stresses and modulate host\u2013pathogen interactions. The outcomes of her research advance the understanding of pathogen health risks and facilitate the sustainable strategies of public health protection.\r\n\r\n\r\nPlease register for this free symposium since lunch will be provided. Thank you!\r\n\r\n\r\nFor more information and registration for this hybrid event:\r\nwww.MAC-EPID.org\r\nAnna Cronenwett, weaverd@umich.edu", "occurrence_notes":null, "guid":"140688-21887538@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/140688", "building_id":"1000191", "building_name":"Michigan League", "building_official_id":1000191, "campus_maps_id":"108", "campus_maps_link_path":"michigan-league", "campus_maps_link":"https:\/\/maps.studentlife.umich.edu\/building\/michigan-league", "room":"Vandenberg Room", "location_name":"Michigan League", "has_livestream":1, "livestream_type":"zoom", "livetream_require_login":0, "livestream_id":"99745620304", "livestream_link":"https:\/\/umich.zoom.us\/j\/99745620304", "cost":"", "tags":["Life Science"], "website":"https:\/\/www.linkedin.com\/groups\/12035996\/", "links":[ { "type":"linkedin", "url":"https:\/\/www.linkedin.com\/groups\/12035996\/", "title":"MAC-EPID on LinkedIn" }, { "type":"other", "url":"https:\/\/sites.google.com\/a\/umich.edu\/mac-epid\/events\/symposia\/current-symposium", "title":"Event Site" } ], "sponsors":[ { "group_name":"MAC-EPID", "group_id":"3261", "website":"http:\/\/mac-epid.org" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2025\/10\/event_140688_original-1.png", "image_description":"The faces of the three guest speakers in various shape frames on a white background.", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2025\/10\/event_140688_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2025\/10\/event_140688_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2025\/10\/event_140688_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2025\/10\/event_140688_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2025\/10\/event_140688_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2025\/10\/event_140688_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2025\/10\/event_140688_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2025\/10\/event_140688_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2025\/10\/event_140688_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2025\/10\/event_140688_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2025\/10\/event_140688_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2025\/10\/event_140688_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2025\/10\/event_140688_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2025\/10\/event_140688_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2025\/10\/event_140688_original-1.png" }, "qr_code_url":"http:\/\/events.umich.edu\/event\/140688\/qrcode.png", "occurrence_count":1, "first_occurrence":21887538 } , { "id":"140436-21887150", "datetime_modified":"20251008T121103", "datetime_start":"20251024T160000", "datetime_end":"20251024T170000", "has_end_time":1, "date_start":"2025-10-24", "date_end":"2025-10-24", "time_start":"16:00:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"CCMB\/DCMB Special Seminar featuring Hagen Tilgner, PhD (Prof. at Weil Cornell Medical College)", "occurrence_title":"", "combined_title":"CCMB\/DCMB Special Seminar featuring Hagen Tilgner, PhD (Prof. at Weil Cornell Medical College): \"A single-cell view of splicing (dys)regulation across in development and the diseases of the brain.\"", "event_subtitle":"\"A single-cell view of splicing (dys)regulation across in development and the diseases of the brain.\"", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Abstract\r\nComplex tissue includes diverse cell types employing distinct RNA isoforms. To untangle full-length cell-type specific brain isoforms, we developed single-cell long-read technology for many thousands of cells (from previous approaches for 10-100 cells) in fresh tissues (ScISOr-Seq; Gupta..Tilgner, 20181) and in frozen tissues (SnISOr-Seq; Hardwick..Tilgner, 20222). These approaches revealed the rules of combination of TSSs, alternative exons and poly(A) sites and their cell-type specificity. Autism-associated exons (as previously described) but also FTD-associated exons are highly variably-used across cell types2. For spatial resolution, we developed spatially-barcoded isoform sequencing with 60um (Joglekar..Tilgner, 20213), 10um (Foord..Tilgner, 20254) and 220nm (Michielsen..Tilgner, biorxiv5) spots, showing that often isoform switches correlate with precise boundaries of brain structures (e.g., choroid plexus to hippocampus). However, genes including Snap25, use a gradient of exon inclusion through the brain3. Choroid plexus epithelial cells show a dramatically distinct isoform profile, which originates most strongly from TSS usage3. During human puberty, layer4-excitatory splicing is more regulated than in other cortical layers \u2013 probably influenced by retroviral sequences4. More generally, we can now detect isoform-expression variability that does not correspond to known brain structures5.\r\n\r\n\r\nFor the NIH Brain Initiative, we have mapped single-cell isoforms across development, brain regions and species. Neurotransmitter release and reuptake as well as synapse turnover genes harbor variability in the same cell type across anatomical regions but the same cell type traced across development shows more isoform variability than across adult anatomical regions. Moreover, most cell-type-specific exons in adult mouse hippocampus behave similarly in human hippocampi. However, human brains have evolved additional cell-type specificity in splicing (Joglekar..Tilgner, 20246). Additionally, the concurrent measurement of chromatin and splicing patterns in post-mortem human brain shows broadly-speaking convergent dysregulation of both modalities in similar cell types in Alzheimer\u2019s disease but more divergence between both modalities in evolution (Hu..Tilgner, 20257). Finally, we have advanced our understanding of error sources of PacBio and ONT (Mikheenko..Tilgner, 20228) and implemented highly accurate long-read software (Prjibelski..Tilgner, 20239).", "occurrence_notes":null, "guid":"140436-21887150@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/140436", "building_id":"1000209", "building_name":"Taubman Library", "building_official_id":1000209, "campus_maps_id":"149", "campus_maps_link_path":"alfred-a-taubman-health-sciences-library", "campus_maps_link":"https:\/\/maps.studentlife.umich.edu\/building\/alfred-a-taubman-health-sciences-library", "room":"2901", "location_name":"Taubman Library", "has_livestream":0, "cost":"", "tags":["Life Science"], "website":"https:\/\/umich.zoom.us\/j\/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09", "links":[ { "type":"livestream", "url":"https:\/\/umich.zoom.us\/j\/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09", "title":"ZOOM Livestream" }, { "type":"other", "url":"https:\/\/medschool.umich.edu\/departments\/computational-medicine-bioinformatics\/ccmb-seminar-hagen-tilgner-phd", "title":"Event Webpage" }, { "type":"other", "url":"https:\/\/www.tilgnerlab.com\/", "title":"Tilgner Lab" } ], "sponsors":[ { "group_name":"Department of Computational Medicine and Bioinformatics DCMB", "group_id":"5384", "website":"" }, { "group_name":"DCMB Seminar Series", "group_id":"3754", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2025\/10\/event_140436_original-1.jpg", "image_description":"Hagen Tilgner, PhD", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2025\/10\/event_140436_original-1.jpg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2025\/10\/event_140436_original-1.jpg", 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It also asks visitors to ponder their own attitudes and experiences, and to submit memories and photos of their time working, studying, volunteering or receiving care at U-M's medical campus and beyond. There are also activities for young visitors.\r\n\r\nThe museum is open to the public every Saturday and Sunday from 12 p.m. to 4 p.m.\r\n\r\nFull details about the exhibit, including parking instructions and how to book a free private group tour on a weekday, are available at http:\/\/michmed.org\/museum\r\n\r\nThe museum has an accessible entrance at the rear of the building.", "occurrence_notes":"Park in nearby municipal lots or structures; on-site parking is extremely limited. Accessible entrance at rear of building off Beakes St.", "guid":"139428-21885480@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/139428", "building_id":"", "building_name":"Off Campus Location", "building_official_id":null, "campus_maps_id":"1", "campus_maps_link_path":"", "campus_maps_link":"", "room":"", "location_name":"500 N. 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"tags":["Life Science"], "website":"https:\/\/twitter.com\/m_leead?lang=en", "links":[ { "type":"twitter", "url":"https:\/\/twitter.com\/m_leead?lang=en", "title":null } ], "sponsors":[ { "group_name":"Michigan Lifestage Environmental Exposures and Disease Center", "group_id":"4335", "website":"https:\/\/twitter.com\/m_leead?lang=en" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2025\/11\/event_141632_original-1.png", "image_description":"Residents & Researchers 'Tuesday Talks at 12' Zoom webinar on environment, health and community. Organized by the Community Engagement Core and the Integrated Health Sciences Core of M-LEEaD. Speakers include: Savannah D\u2019Evelyn, PhD (University of Colorado Denver) and Callum Orr (Grand Junction High School, Grand Junction, CO). Moderated by Natalie Sampson (University of Michigan Dearborn).", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2025\/11\/event_141632_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2025\/11\/event_141632_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_2x\/media\/attachments\/2025\/11\/event_141632_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2025\/11\/event_141632_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2025\/11\/event_141632_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2025\/11\/event_141632_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2025\/11\/event_141632_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large_lightbox\/media\/attachments\/2025\/11\/event_141632_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2025\/11\/event_141632_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2025\/11\/event_141632_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2025\/11\/event_141632_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid\/media\/attachments\/2025\/11\/event_141632_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2025\/11\/event_141632_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_large\/media\/attachments\/2025\/11\/event_141632_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2025\/11\/event_141632_original-1.png" }, "qr_code_url":"http:\/\/events.umich.edu\/event\/141632\/qrcode.png", "occurrence_count":1, "first_occurrence":21889116 } , { "id":"139256-21885202", "datetime_modified":"20251024T114919", "datetime_start":"20251113T150000", "datetime_end":"20251113T163000", "has_end_time":1, "date_start":"2025-11-13", "date_end":"2025-11-13", "time_start":"15:00:00", "time_end":"16:30:00", "time_zone":"America\/Detroit", "event_title":"McKesson Foundation Health Equity Speaker Series: Utibe R. Essien, MD, MPH", "occurrence_title":"", "combined_title":"McKesson Foundation Health Equity Speaker Series: Utibe R. Essien, MD, MPH", "event_subtitle":"", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"McKesson Foundation Health Equity Speaker Series: Utibe R. Essien, MD, MPH\r\nDate: Thursday November 13, 2025\r\nTime: 3:00 pm \u2013 4:30 pm\r\nLocation: Palmer Commons, Great Lakes Room, 100 Washtenaw Ave, Ann Arbor, MI 48109\r\nTitle: Pursuing Pharmacoequity: A Prescription for Health\r\n\r\nThis event is free of cost. Refreshments will be provided. RSVP is requested to aid in an accurate headcount for catering. Please help us be good stewards of University resources and update your response if plans change.\r\n\r\nCoined by Utibe R. Essien, MD, MPH, pharmacoequity is defined as \u201censuring all individuals, regardless of race and ethnicity, socioeconomic status, or availability of resources, have access to the highest-quality medications required to manage their health needs.\u201d. The goal of this talk is to explain the concept of pharmacoequity and how individuals can apply this knowledge to their practice and communities.\r\n\r\nSpeaker\r\nUtibe R. Essien, MD, MPH\r\nAssistant Professor of Medicine, David Geffen School of Medicine, University of California Los Angeles; Associate Vice Chair, Community Engagement and Inclusive Excellence, Department of Medicine\r\n\r\nBiography\r\nUtibe R. Essien, MD, MPH, FACP is a board-certified, internal medicine physician, an Assistant Professor of Medicine and health equity researcher at the David Geffen School of Medicine at UCLA. A proud New Yorker, Dr. Essien received his MD from the Albert Einstein College of Medicine in the Bronx, NY before training in internal medicine at Massachusetts General Hospital (MGH) and Harvard Medical School. After residency he remained at MGH to complete a General Internal Medicine fellowship and receive an MPH degree from the Harvard School of Public Health.\r\n\r\nDr. Essien\u2019s research focuses on disparities in the use of novel medications and technologies, particularly in the management of cardiovascular diseases. In 2021, he coined the term \u201cpharmacoequity,\u201d providing a new framework to achieving equitable access to care. He is an emerging leader in the field, as recognized by over 120 peer-reviewed publications and research grants from the Department of Veterans Affairs and the American Heart Association. His research has earned him numerous national awards including a 2023 Young Physician Scientist Award from the American Society for Clinical Investigation (ASCI), the 2024 Society of General Internal Medicine (SGIM) Outstanding Junior Investigator of the Year Award, and selection as an Emerging Leader in Health and Medicine by the National Academy of Medicine (NAM).\r\n\r\nMcKesson Foundation Health Equity Speaker Series\r\n\r\nDisparities in health and healthcare have been are prevalent, particularly in underserved or minority communities, as a result of a variety of factors such as birthplace, housing, education, race, age, sexual identity and other nonmedical factors. These factors are commonly referred to as the social determinants of health (SDOH). As a result of SDOH, quality healthcare and treatment can be difficult to access for many who don\u2019t fall into the dominant group and must confront barriers to receive treatment.\r\n\r\nExamples of barriers to adequate healthcare treatment include poverty, lack of access to quality education or positive social activities, and unhealthy environmental factors. These factors must be addressed in order to achieve positive health outcomes and equity in access to healthcare and treatment for all. To help illuminate and educate around issues involving social determinants of health, the College of Pharmacy and the McKesson Foundation have teamed up to launch the McKesson Foundation Health Equity Speaker Series.\r\n\r\nFor the past two years the College of Pharmacy at the University of Michigan in partnership with the McKesson Foundation has hosted a speaker series based on the topic of health equity. The McKesson Foundation is dedicated to advancing health outcomes for all with the mission to removing barriers to quality healthcare across the country, especially for vulnerable and underserved communities. The College of Pharmacy also has a longstanding history of fighting to address addressing disparities in healthcare and is a leader in the fight for equitable healthcare for all individuals. This alignment in values and mission of both organizations led to the provision awarding of a grant to resulted in the College of Pharmacy being awarded a grant in 2022 to launch what we now call the McKesson Foundation Health Equity Speaker Series, with the goal of educating the UM community and inspiring those around us to find solutions that address inequities in healthcare and beyond.\r\n\r\nAbout our Funder, the McKesson Foundation\r\nThe McKesson Foundation is a charitable organization dedicated to improving health outcomes for vulnerable and underserved populations. It focuses on initiatives that address healthcare disparities, promote patient-centered care, and support cancer care and survivorship. Through grants, partnerships, and employee-driven giving programs, the foundation aims to foster innovative solutions that enhance community health and well-being.", "occurrence_notes":"RSVP is requested", "guid":"139256-21885202@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/139256", "building_id":"1005047", "building_name":"Palmer Commons", "building_official_id":1005047, "campus_maps_id":"188", "campus_maps_link_path":"palmer-commons", "campus_maps_link":"https:\/\/maps.studentlife.umich.edu\/building\/palmer-commons", "room":"Great Lakes Room 100 Washtenaw Ave Ann Arbor, MI, 48109", "location_name":"Palmer Commons", "has_livestream":0, "cost":"", "tags":["Life Science"], "website":"https:\/\/pharmacy.umich.edu\/events\/mckesson-foundation-health-equity-speaker-series-dr-utibe-r-essien\/", "links":[ { "type":"other", "url":"https:\/\/pharmacy.umich.edu\/events\/mckesson-foundation-health-equity-speaker-series-dr-utibe-r-essien\/", "title":"College of Pharmacy website event listing" }, { "type":"registration", "url":"https:\/\/docs.google.com\/forms\/d\/e\/1FAIpQLSeQrDw_xhyXVtMnJlnGz5d9VfN6GXP5uVJksnLdie936lVErg\/viewform", "title":"RSVP form" }, { "type":"other", "url":"https:\/\/www.uressien.com\/", "title":"Utibe R. Essien's website" } ], "sponsors":[ { "group_name":"U-M College of Pharmacy", "group_id":"3527", "website":"" }, { "group_name":"Michigan Medicine", "group_id":"1033", "website":"https:\/\/www.facebook.com\/MichiganMedicine\/" }, { "group_name":"School of Social Work", "group_id":"1158", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2025\/10\/event_139256_original-3.jpg", "image_description":"Event flyer for McKesson Speaker Series Presents \"Pursuing Pharmacoequity: A Prescription for Health\" Featuring Dr. Utibe R. 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Could bioinformatics be your calling? Find out more about what bioinformatics is, what it takes to get into this field, what a day in the life of a bioinformatician looks like, and what career opportunities it offers.\r\n\r\nThe open house will include presentations by University of Michigan faculty, small group meetings with faculty, and a discussion of career tracks. 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It also asks visitors to ponder their own attitudes and experiences, and to submit memories and photos of their time working, studying, volunteering or receiving care at U-M's medical campus and beyond. There are also activities for young visitors.\r\n\r\nThe museum is open to the public every Saturday and Sunday from 12 p.m. to 4 p.m.\r\n\r\nFull details about the exhibit, including parking instructions and how to book a free private group tour on a weekday, are available at http:\/\/michmed.org\/museum\r\n\r\nThe museum has an accessible entrance at the rear of the building.", "occurrence_notes":"Park in nearby municipal lots or structures; on-site parking is extremely limited. 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In this talk, he explores why virtue, character and the habits of moral perception are essential \u2014 not optional \u2014 in shaping physicians who can care wisely and humanely for the most vulnerable. \r\n\r\nDr. Antiel will present one such effort underway at Duke University: The Good Surgeon. Drawing on strategies from the Oxford Leadership Initiative, this project seeks to counter professional corrosion by forming a parallel community rooted in friendship, mutual accountability and honest inquiry. Within this space, difficult questions are raised, new practices are tested and the seeds of durable professional identity are cultivated. 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"datetime_modified":"20260324T094536", "datetime_start":"20260124T120000", "datetime_end":"20260124T160000", "has_end_time":1, "date_start":"2026-01-24", "date_end":"2026-01-24", "time_start":"12:00:00", "time_end":"16:00:00", "time_zone":"America\/Detroit", "event_title":"Creating the Future of Medicine for 175 Years", "occurrence_title":"", "combined_title":"Creating the Future of Medicine for 175 Years: A free museum exhibit about U-M medical history", "event_subtitle":"A free museum exhibit about U-M medical history", "event_type":"Exhibition", "event_type_id":"7", "description":"As the Medical School celebrates the anniversary of its opening in the fall of 1850, and Michigan Medicine marks the 100th anniversary of the opening of the \"Old Main\" University Hospital that served as its flagship from 1925 to 1986, a free museum exhibit explores 175 years of medical education, research and clinical care. \r\n\r\nOpen to the public at the Museum on Main Street operated by the Washtenaw 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It also asks visitors to ponder their own attitudes and experiences, and to submit memories and photos of their time working, studying, volunteering or receiving care at U-M's medical campus and beyond. There are also activities for young visitors.\r\n\r\nThe museum is open to the public every Saturday and Sunday from 12 p.m. to 4 p.m.\r\n\r\nFull details about the exhibit, including parking instructions and how to book a free private group tour on a weekday, are available at http:\/\/michmed.org\/museum\r\n\r\nThe museum has an accessible entrance at the rear of the building.", "occurrence_notes":"Park in nearby municipal lots or structures; on-site parking is extremely limited. Accessible entrance at rear of building off Beakes St.", "guid":"139428-21885493@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/139428", "building_id":"", "building_name":"Off Campus Location", "building_official_id":null, "campus_maps_id":"1", "campus_maps_link_path":"", "campus_maps_link":"", "room":"", "location_name":"500 N. Main Street, Ann Arbor MI 48104 at the intersection of Main, Kingsley and Beakes streets", "has_livestream":0, "cost":"", "tags":["Life Science"], "website":"http:\/\/michmed.org\/museum", "links":[ { "type":"other", "url":"http:\/\/michmed.org\/museum", "title":"Exhibit details" }, { "type":"facebook", "url":"https:\/\/www.facebook.com\/MichiganMedicine\/", "title":"Michigan Medicine Facebook" } ], "sponsors":[ { "group_name":"Michigan Medicine", "group_id":"1033", "website":"https:\/\/www.facebook.com\/MichiganMedicine\/" }, { "group_name":"Bentley Historical Library", "group_id":"2901", "website":"http:\/\/bentley.umich.edu" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "image_description":"Artifacts from an early-20th century U-M microbiology laboratory", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2025\/09\/event_139428_original-1.jpg" }, "qr_code_url":"http:\/\/events.umich.edu\/event\/139428\/qrcode.png", "occurrence_count":100, "first_occurrence":21885475 } , { "id":"139428-21885525", "datetime_modified":"20260324T094536", "datetime_start":"20260125T120000", "datetime_end":"20260125T160000", "has_end_time":1, "date_start":"2026-01-25", "date_end":"2026-01-25", "time_start":"12:00:00", "time_end":"16:00:00", "time_zone":"America\/Detroit", "event_title":"Creating the Future of Medicine for 175 Years", "occurrence_title":"", "combined_title":"Creating the Future of Medicine for 175 Years: A free museum exhibit about U-M medical history", "event_subtitle":"A free museum exhibit about U-M medical history", "event_type":"Exhibition", "event_type_id":"7", "description":"As the Medical School celebrates the anniversary of its opening in the fall of 1850, and Michigan Medicine marks the 100th anniversary of the opening of the \"Old Main\" University Hospital that served as its flagship from 1925 to 1986, a free museum exhibit explores 175 years of medical education, research and clinical care. \r\n\r\nOpen to the public at the Museum on Main Street operated by the Washtenaw County Historical Society, the exhibit includes artifacts, photos and facts about how U-M's medical community grew from humble beginnings on the Diag to become one of the nation's largest and most respected academic medical centers. It also asks visitors to ponder their own attitudes and experiences, and to submit memories and photos of their time working, studying, volunteering or receiving care at U-M's medical campus and beyond. There are also activities for young visitors.\r\n\r\nThe museum is open to the public every Saturday and Sunday from 12 p.m. to 4 p.m.\r\n\r\nFull details about the exhibit, including parking instructions and how to book a free private group tour on a weekday, are available at http:\/\/michmed.org\/museum\r\n\r\nThe museum has an accessible entrance at the rear of the building.", "occurrence_notes":"Park in nearby municipal lots or structures; on-site parking is extremely limited. Accessible entrance at rear of building off Beakes St.", "guid":"139428-21885525@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/139428", "building_id":"", "building_name":"Off Campus Location", "building_official_id":null, "campus_maps_id":"1", "campus_maps_link_path":"", "campus_maps_link":"", "room":"", "location_name":"500 N. Main Street, Ann Arbor MI 48104 at the intersection of Main, Kingsley and Beakes streets", "has_livestream":0, "cost":"", "tags":["Life Science"], "website":"http:\/\/michmed.org\/museum", "links":[ { "type":"other", "url":"http:\/\/michmed.org\/museum", "title":"Exhibit details" }, { "type":"facebook", "url":"https:\/\/www.facebook.com\/MichiganMedicine\/", "title":"Michigan Medicine Facebook" } ], "sponsors":[ { "group_name":"Michigan Medicine", "group_id":"1033", "website":"https:\/\/www.facebook.com\/MichiganMedicine\/" }, { "group_name":"Bentley Historical Library", "group_id":"2901", "website":"http:\/\/bentley.umich.edu" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "image_description":"Artifacts from an early-20th century U-M microbiology laboratory", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2025\/09\/event_139428_original-1.jpg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2025\/09\/event_139428_original-1.jpg" }, "qr_code_url":"http:\/\/events.umich.edu\/event\/139428\/qrcode.png", "occurrence_count":100, "first_occurrence":21885475 } , { "id":"143129-21892187", "datetime_modified":"20260124T161004", "datetime_start":"20260125T160000", "datetime_end":"20260125T183000", "has_end_time":1, "date_start":"2026-01-25", "date_end":"2026-01-25", "time_start":"16:00:00", "time_end":"18:30:00", "time_zone":"America\/Detroit", "event_title":"Life Sciences Orchestra Concert", "occurrence_title":"", "combined_title":"Life Sciences Orchestra Concert: Dedicated to the Memory of Dr. Robert Bartlett", "event_subtitle":"Dedicated to the Memory of Dr. Robert Bartlett", "event_type":"Performance", "event_type_id":"15", "description":"This event will proceed despite the Winter Weather Advisory; please allow extra time for travel. A livestream is also available at https:\/\/michmed.org\/rw2W3\n\nThe U-M orchestra made up of faculty, staff, learners, alumni and retirees from across U-M's biomedical and health science community will play a free concert at 4 p.m. on Sunday, Jan. 25 at Hill Auditorium.\n\nThe performance will feature these works: \nLili Boulanger - D'un Matin de Printemps\nAaron Copland - The Tender Land Suite \nCarl Nielsen - Symphony No. 4, Op. 29, \"The Inextinguishable\"\n\nThe concert is dedicated to the memory of LSO founding member and U-M critical care giant Dr. Robert Bartlett. \n\nMusic director Nicholas Bromilow will give a pre-concert talk at 3:15 p.m. in the lower level of the lobby. He and assistant conductor Michael Roest are students at the U-M School of Music, Theatre and Dance's nationally renowned conducting program.\n\nNo tickets are required for the performance. The LSO is part of Gifts of Art, which brings the world of art to Michigan Medicine. \n\nMore information: https:\/\/michmed.org\/ZxjDq or email orchestra@umich.edu", "occurrence_notes":"Pre-concert lecture at 3:15 in lower level", "guid":"143129-21892187@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/143129", "building_id":"1000177", "building_name":"Hill Auditorium", "building_official_id":1000177, "campus_maps_id":"69", "campus_maps_link_path":"hill-auditorium", "campus_maps_link":"https:\/\/maps.studentlife.umich.edu\/building\/hill-auditorium", "room":"", "location_name":"Hill Auditorium", "has_livestream":0, "cost":"", "tags":["Life Science"], "website":"https:\/\/www.facebook.com\/umlso", "links":[ { "type":"facebook", "url":"https:\/\/www.facebook.com\/umlso", "title":"LSO Facebook page" }, { "type":"other", "url":"https:\/\/michmed.org\/ZxjDq", "title":"Concert information" }, { "type":"livestream", 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"permalink":"http:\/\/events.umich.edu\/event\/141985", "building_id":"1005037", "building_name":"Taubman Biomedical Science Research Building", "building_official_id":1005037, "campus_maps_id":"509", "campus_maps_link_path":"alfred-a-taubman-biomedical-science-research-bldg", "campus_maps_link":"https:\/\/maps.studentlife.umich.edu\/building\/alfred-a-taubman-biomedical-science-research-bldg", "room":"ABC Seminar Rooms", "location_name":"Taubman Biomedical Science Research Building", "has_livestream":0, "cost":"", "tags":["Life Science"], "website":"https:\/\/medresearch.umich.edu\/labs-departments\/centers\/cell-plasticity-organ-design\/cpod-winter-2026-seminar-series-visualizing-gene-regulation-post-traumatic-brain-injury-spatial", "links":[ { "type":"other", "url":"https:\/\/medresearch.umich.edu\/labs-departments\/centers\/cell-plasticity-organ-design\/cpod-winter-2026-seminar-series-visualizing-gene-regulation-post-traumatic-brain-injury-spatial", "title":null } ], "sponsors":[ { 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"combined_title":"Mathematical Biology Seminar: How much data is needed to validate multiscale models of viral infections?: Stanca Ciupe, PhD (Virginia Tech)", "event_subtitle":"Stanca Ciupe, PhD (Virginia Tech)", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Uncertainty in parameter estimates from fitting mathematical models to empirical data limits the model\u2019s ability to uncover mechanisms of interaction. Understanding the effect of model structure and data availability on model predictions is important for informing model development and experimental design. To address sources of uncertainty in parameter estimation, I will present methodologies that can help determine when a model can reveal its parameters. I will apply them in the context of virus infections in animals and humans at within-host, population, and multiscale levels. Using these approaches, I will provide insight into the sources of uncertainty and provide guidelines for the types of model assumptions, optimal experimental design, and biological information needed for improved predictions.\n\nThis seminar is hybrid: meeting in Weiser 296 and via Zoom:\nhttps:\/\/umich.zoom.us\/j\/97725897086\nMeeting ID: 977 2589 7086\nPasscode: mathbio", "occurrence_notes":"Hybrid option via Zoom: https:\/\/umich.zoom.us\/j\/97725897086 password mathbio", "guid":"143969-21895434@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/143969", "building_id":"1000165", "building_name":"Weiser Hall", "building_official_id":1000165, "campus_maps_id":"47", "campus_maps_link_path":"weiser-hall", "campus_maps_link":"https:\/\/maps.studentlife.umich.edu\/building\/weiser-hall", "room":"296", "location_name":"Weiser Hall", "has_livestream":0, "cost":"", "tags":["Life Science"], "website":"", "links":[ ], "sponsors":[ { "group_name":"Mathematical Biology - Department of Mathematics", "group_id":"5455", "website":"" }, { "group_name":"Department of Mathematics", "group_id":"3791", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/01\/event_143969_original-1.png", "image_description":"Photo of Dr. Stanca Ciupe", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2026\/01\/event_143969_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/01\/event_143969_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2026\/01\/event_143969_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2026\/01\/event_143969_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2026\/01\/event_143969_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2026\/01\/event_143969_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2026\/01\/event_143969_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2026\/01\/event_143969_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2026\/01\/event_143969_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2026\/01\/event_143969_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2026\/01\/event_143969_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2026\/01\/event_143969_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2026\/01\/event_143969_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2026\/01\/event_143969_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2026\/01\/event_143969_original-1.png" }, "qr_code_url":"http:\/\/events.umich.edu\/event\/143969\/qrcode.png", "occurrence_count":1, "first_occurrence":21895434 } , { "id":"143191-21892406", "datetime_modified":"20260105T124948", "datetime_start":"20260129T120000", "datetime_end":"20260129T130000", "has_end_time":1, "date_start":"2026-01-29", "date_end":"2026-01-29", "time_start":"12:00:00", "time_end":"13:00:00", "time_zone":"America\/Detroit", "event_title":"DCMB Tools and Technology Seminar by Haoran Li", "occurrence_title":"", "combined_title":"DCMB Tools and Technology Seminar by Haoran Li: \u201cImproving gene isoform quantification with miniQuant\u201d", "event_subtitle":"\u201cImproving gene isoform quantification with miniQuant\u201d", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Abstract\r\nRNA sequencing has been widely applied for gene isoform quantification, but limitations exist in quantifying isoforms of complex genes accurately, especially for short reads. 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In this lecture, I will explore a new way of thinking about neural networks\u2014where signals travel as waves across curved surfaces, and learning happens by slowly reshaping the space through which those waves flow. Using networks inspired by cells arranged as 3D \u201cdigital neural organoids\u201d, I will illustrate how activity spreads across layered, spherical networks, forming wavefronts, spirals, and rhythmic patterns. These waves are not just visual curiosities: their timing, direction, and stability determine how well information reaches key regions of the system. By modulating the positions of individual nodes, the network trains itself, focusing signals inward, synchronizing their arrival, and reducing noise\u2014much like adjusting the shape of a lens to bring an image into view. The lecture will include animated visualizations of nested organoid surfaces changing over time, directing signals toward a central core, and sometimes swirling into persistent spatial patterns that can store information. No particularly advanced mathematics is required. Instead, I hope to build intuition around familiar ideas\u2014waves, flow, and geometry\u2014to show how learning and computation might emerge from space itself. This fresh perspective opens new ways to think about brain development, artificial intelligence, and the future of biologically inspired computing.", "occurrence_notes":null, "guid":"143689-21893651@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/143689", "building_id":"1000190", "building_name":"Medical Science Unit I", "building_official_id":1000190, "campus_maps_id":"104", "campus_maps_link_path":"medical-science-unit-i", "campus_maps_link":"https:\/\/maps.studentlife.umich.edu\/building\/medical-science-unit-i", "room":"4B700", "location_name":"Medical Science Unit I", "has_livestream":0, "cost":"", "tags":["Life Science"], "website":"https:\/\/umich.zoom.us\/j\/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09", "links":[ { "type":"livestream", "url":"https:\/\/umich.zoom.us\/j\/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09", "title":"ZOOM Livestream" }, { "type":"other", "url":"https:\/\/medschool.umich.edu\/events\/ccmb-seminar-series\/ccmb-seminar-jack-van-horn-phd\/2026-02-18", "title":"Event Webpage" } ], "sponsors":[ { "group_name":"DCMB Seminar Series", "group_id":"3754", "website":"" }, { "group_name":"Department of Computational Medicine and Bioinformatics DCMB", "group_id":"5384", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/01\/event_143689_original-1.png", "image_description":"John Van Horn PhD", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2026\/01\/event_143689_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/01\/event_143689_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2026\/01\/event_143689_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2026\/01\/event_143689_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2026\/01\/event_143689_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2026\/01\/event_143689_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2026\/01\/event_143689_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2026\/01\/event_143689_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2026\/01\/event_143689_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2026\/01\/event_143689_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2026\/01\/event_143689_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2026\/01\/event_143689_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2026\/01\/event_143689_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2026\/01\/event_143689_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2026\/01\/event_143689_original-1.png" }, "qr_code_url":"http:\/\/events.umich.edu\/event\/143689\/qrcode.png", "occurrence_count":1, "first_occurrence":21893651 } , { "id":"143260-21892595", "datetime_modified":"20260106T103655", "datetime_start":"20260219T120000", "datetime_end":"20260219T130000", "has_end_time":1, "date_start":"2026-02-19", "date_end":"2026-02-19", "time_start":"12:00:00", "time_end":"13:00:00", "time_zone":"America\/Detroit", "event_title":"DCMB Tools and Technology Seminar by Mukai Wang", "occurrence_title":"", "combined_title":"DCMB Tools and Technology Seminar by Mukai Wang: \u201cADAPT: Analysis of Microbiome Differential Abundance by Pooling Tobit Models\u201d", "event_subtitle":"\u201cADAPT: Analysis of Microbiome Differential Abundance by Pooling Tobit Models\u201d", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Abstract\r\nMicrobiome differential abundance analysis remains a challenging problem despite multiple methods proposed in the literature. The excessive zeros and compositionality of metagenomics data are two main challenges for differential abundance analysis. We propose a novel method called \u201canalysis of differential abundance by pooling Tobit models\u201d (ADAPT) to overcome these two challenges. ADAPT uniquely treats zero counts as left-censored observations to facilitate computation and enhance interpretation. ADAPT also encompasses a theoretically justified way of selecting non-differentially abundant microbiome taxa as a reference for hypothesis testing. We generate synthetic data using independent simulation frameworks to show that ADAPT has more consistent false discovery rate control and higher statistical power than competitors. We use ADAPT to analyze 16S rRNA sequencing of saliva samples and shotgun metagenomics sequencing of plaque samples collected from infants in the COHRA2 study. The results provide novel insights into the association between the oral microbiome and early childhood dental caries.\r\n\r\nAbout the DCMB Tools & Technology Seminar Series\r\n\r\nThe DCMB Tools and Technology Seminar Series is held in Medical Science Building 1 (MS1), Room 4B700, each Thursday at 12pm EST. Each seminar highlights a computational tool, technology, or methodology that is under development or in current use and is of special interest to DCMB and University researchers. Presenters are U-M researchers and students.\r\n\r\nThese seminars are live-streamed and recorded and made available for future viewing via the DCMB YouTube ChannelAbout the DCMB Tools & Technology Seminar Series\r\n\r\nThe DCMB Tools and Technology Seminar Series is held in Medical Science Building 1 (MS1), Room 4B700, each Thursday at 12pm EST. Each seminar highlights a computational tool, technology, or methodology that is under development or in current use and is of special interest to DCMB and University researchers. 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"guid":"144320-21895161@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/144320", "building_id":"1000204", "building_name":"Public Health I (Vaughan Building)", "building_official_id":1000204, "campus_maps_id":"61", "campus_maps_link_path":"henry-frieze-vaughan-school-of-public-health-building", "campus_maps_link":"https:\/\/maps.studentlife.umich.edu\/building\/henry-frieze-vaughan-school-of-public-health-building", "room":"1655", "location_name":"Public Health I (Vaughan Building)", "has_livestream":0, "cost":"", "tags":["Life Science"], "website":"", "links":[ ], "sponsors":[ { "group_name":"Michigan Lifestage Environmental Exposures and Disease Center", "group_id":"4335", "website":"https:\/\/twitter.com\/m_leead?lang=en" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/01\/event_144320_original-1.png", "image_description":"Feb 20 Environmental Statistics Day, Keynote lecture: Statistics and machine learning for studying air pollution using 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It also asks visitors to ponder their own attitudes and experiences, and to submit memories and photos of their time working, studying, volunteering or receiving care at U-M's medical campus and beyond. There are also activities for young visitors.\r\n\r\nThe museum is open to the public every Saturday and Sunday from 12 p.m. to 4 p.m.\r\n\r\nFull details about the exhibit, including parking instructions and how to book a free private group tour on a weekday, are available at http:\/\/michmed.org\/museum\r\n\r\nThe museum has an accessible entrance at the rear of the building.", "occurrence_notes":"Park in nearby municipal lots or structures; on-site parking is extremely limited. 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It also asks visitors to ponder their own attitudes and experiences, and to submit memories and photos of their time working, studying, volunteering or receiving care at U-M's medical campus and beyond. There are also activities for young visitors.\r\n\r\nThe museum is open to the public every Saturday and Sunday from 12 p.m. to 4 p.m.\r\n\r\nFull details about the exhibit, including parking instructions and how to book a free private group tour on a weekday, are available at http:\/\/michmed.org\/museum\r\n\r\nThe museum has an accessible entrance at the rear of the building.", "occurrence_notes":"Park in nearby municipal lots or structures; on-site parking is extremely limited. 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Although Atwood\u2019s narrative is fiction, the realities of forced reproduction and restricted bodily autonomy have long impacted women of color, low-income women, disabled women, and people of diverse gender identities, making this story compelling and profoundly relevant today. The novel\u2019s evolution into a television show and now, an opera reflects its sustained cultural and political resonance. This event, co-hosted by the Detroit Opera and the University of Michigan\u2019s Center for History, Humanities, Arts, Social Sciences, and Ethics in Medicine, will feature a free, moderated discussion about the operatic adaptation of The Handmaid\u2019s Tale. Together, we will explore how artistic representations can stimulate important conversations about reproductive justice, structural power, and the ongoing struggles faced by women and people of marginalized genders. 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He is a member of the Harvard Biophysics Program and the Harvard Initiative for RNA Medicine (HIRM). He received his undergraduate and Ph.D. degrees from the University of California in Santa Cruz and performed postdoctoral studies at the University of California in San Francisco.\r\n\r\nThe Moazed lab studies how genes are silenced and how silencing is epigenetically inherited across generations. The lab\u2019s interests revolve around diverse pathways of heterochromatin-mediated gene silencing in yeast and mammalian cells. Work in budding yeast focuses on the structure and function of a diverged and relatively simple form of heterochromatin, which requires only three Silent information regulator (\u201cSir\u201d) proteins that form a histone deacetylase and chromatin-binding complex. Work in fission yeast focuses on a conserved example of heterochromatin that requires the nuclear RNA interference (RNAi) machinery, other RNA processing pathways, Heterochromatin protein 1 (HP1) homologs, and histone-modifying enzymes. In mammalian cells, the work is focused on HP1-mediated and other heterochromatin formation pathways. The lab uses approaches ranging from genetics and genomics, biochemical purification and reconstitution, and structural biology for their studies. 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"qr_code_url":"http:\/\/events.umich.edu\/event\/142424\/qrcode.png", "occurrence_count":1, "first_occurrence":21890940 } , { "id":"145768-21897796", "datetime_modified":"20260220T102635", "datetime_start":"20260326T100000", "datetime_end":"20260326T114500", "has_end_time":1, "date_start":"2026-03-26", "date_end":"2026-03-26", "time_start":"10:00:00", "time_end":"11:45:00", "time_zone":"America\/Detroit", "event_title":"SCSAP Special Research Seminar and Town Hall Event", "occurrence_title":"", "combined_title":"SCSAP Special Research Seminar and Town Hall Event: Aviv Regev, PhD, Genentech", "event_subtitle":"Aviv Regev, PhD, Genentech", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"SCSAP Special Research Seminar and Town Hall Discussion Event\nDate: Thursday, March 26, 2026\nLocation: Live In-Person Only (Will not be streamed or recorded)\n NCRC Building 18, Dining Hall\nFREE TO ALL, Everyone is Welcome, \nLite Refreshments provided\n\nFEATURING: Dr. Aviv Regev, Executive Vice President and Head of Genentech Research and Early Development and Executive Committee of the Human Cell Atlas\n\n*PLEASE REGISTER FOR THIS EVENT*\n\nTwo Events of Interest: \n\n10:00\u201310:45 AM- Talk Title: \u201cTowards Unified Cell and Tissue Oracles\u201d- Featuring Dr. Regev- Hosted by SCSAP \n\n11:00\u201311:45 AM Town Hall Discussion Featuring Dr. Regev and an invited faculty panel \u2013 event will cover several topics such as the future of single cell spatial-omics, strategies for productive collaboration, AI development of new drugs.", "occurrence_notes":null, "guid":"145768-21897796@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/145768", "building_id":"", "building_name":"North Campus Research Complex Building 18", "building_official_id":0, "campus_maps_id":"595", "campus_maps_link_path":"north-campus-research-complex-building-18", "campus_maps_link":"https:\/\/maps.studentlife.umich.edu\/building\/north-campus-research-complex-building-18", "room":"Dining Hall", "location_name":"North Campus Research Complex Building 18", "has_livestream":0, "cost":"", "tags":["Life Science"], "website":"https:\/\/forms.gle\/HszvbgtbRx1bgSfY7", "links":[ { "type":"registration", "url":"https:\/\/forms.gle\/HszvbgtbRx1bgSfY7", "title":"Registration" }, { "type":"other", "url":"https:\/\/singlecellspatialanalysis.umich.edu\/special-research-seminar\/", "title":"Learn More Here" } ], "sponsors":[ { "group_name":"Single Cell Spatial Analysis Program (SCSAP)", "group_id":"4668", "website":"" }, { "group_name":"Life Sciences Institute (LSI)", "group_id":"1067", "website":"https:\/\/twitter.com\/UMLifeSciences" }, { "group_name":"Department of Computational Medicine and Bioinformatics DCMB", "group_id":"5384", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/02\/event_145768_original-1.png", 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GWAS\"", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Abstract\r\nGenomic data from a single institution lacks global diversity representation, especially for rare variants and diseases. Confidential computing can enable collaborative genome-wide association studies (GWAS) without compromising privacy or accuracy. However, due to limited secure memory space and performance overheads, previous solutions fail to support widely used regression methods. Here we present SECRET-GWAS\u2014a rapid, privacy-preserving, population-scale, collaborative GWAS tool. We discuss several system optimizations, including streaming, batching, data parallelization and reducing trusted hardware overheads to efficiently scale linear and logistic regression to over a thousand processor cores on an Intel SGX-based cloud platform. In addition, we protect SECRET-GWAS against several hardware side-channel attacks. SECRET-GWAS is an open-source tool and works with the widely used Hail genomic analysis framework. Our experiments on Azure\u2019s Confidential Computing platform demonstrate that SECRET-GWAS enables multivariate linear and logistic regression GWAS queries on population-scale datasets from ten independent sources in just 4.5 and 29 minutes, respectively.\r\n\r\nAbout the DCMB Tools & Technology Seminar Series\r\n\r\nThe DCMB Tools and Technology Seminar Series is held in Medical Science Building 1 (MS1), Room 4B700, each Thursday at 12pm EST. Each seminar highlights a computational tool, technology, or methodology that is under development or in current use and is of special interest to DCMB and University researchers. Presenters are U-M researchers and students.\r\n\r\nThese seminars are live-streamed and recorded and made available for future viewing via the DCMB YouTube Channel", "occurrence_notes":null, "guid":"143264-21892599@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/143264", "building_id":"1000190", "building_name":"Medical Science Unit I", "building_official_id":1000190, "campus_maps_id":"104", "campus_maps_link_path":"medical-science-unit-i", "campus_maps_link":"https:\/\/maps.studentlife.umich.edu\/building\/medical-science-unit-i", "room":"Room 4B700", "location_name":"Medical Science Unit I", "has_livestream":0, "cost":"", "tags":["Life Science"], "website":"https:\/\/umich.zoom.us\/j\/94417089006", "links":[ { "type":"livestream", "url":"https:\/\/umich.zoom.us\/j\/94417089006", "title":"ZOOM Livestream" }, { "type":"other", "url":"https:\/\/medschool.umich.edu\/events\/tools-technology-seminar-series\/tools-and-technology-seminar-jonah-rosenblum\/2026-03-26", "title":"Event Webpage" }, { "type":"youtube", "url":"https:\/\/www.youtube.com\/channel\/UCjvLXvfPupVHtGU_ckTDPwA\/videos", "title":"DCMB YouTube Channel" } ], "sponsors":[ { "group_name":"Department of Computational Medicine and Bioinformatics DCMB", "group_id":"5384", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/01\/event_143264_original-1.png", "image_description":"DCMB Logo", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2026\/01\/event_143264_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/01\/event_143264_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2026\/01\/event_143264_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2026\/01\/event_143264_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2026\/01\/event_143264_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2026\/01\/event_143264_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2026\/01\/event_143264_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2026\/01\/event_143264_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2026\/01\/event_143264_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2026\/01\/event_143264_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2026\/01\/event_143264_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2026\/01\/event_143264_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2026\/01\/event_143264_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2026\/01\/event_143264_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2026\/01\/event_143264_original-1.png" }, "qr_code_url":"http:\/\/events.umich.edu\/event\/143264\/qrcode.png", "occurrence_count":1, "first_occurrence":21892599 } , { "id":"139428-21885502", "datetime_modified":"20260324T094536", "datetime_start":"20260328T120000", "datetime_end":"20260328T160000", "has_end_time":1, "date_start":"2026-03-28", "date_end":"2026-03-28", "time_start":"12:00:00", "time_end":"16:00:00", "time_zone":"America\/Detroit", "event_title":"Creating the Future of Medicine for 175 Years", "occurrence_title":"", "combined_title":"Creating the Future of Medicine for 175 Years: A free museum exhibit about U-M medical history", "event_subtitle":"A free museum exhibit about U-M medical history", "event_type":"Exhibition", "event_type_id":"7", "description":"As the Medical School celebrates the anniversary of its opening in the fall of 1850, and Michigan Medicine marks the 100th anniversary of the opening of the \"Old Main\" University Hospital that served as its flagship from 1925 to 1986, a free museum exhibit explores 175 years of medical education, research and clinical care. \r\n\r\nOpen to the public at the Museum on Main Street operated by the Washtenaw County Historical Society, the exhibit includes artifacts, photos and facts about how U-M's medical community grew from humble beginnings on the Diag to become one of the nation's largest and most respected academic medical centers. It also asks visitors to ponder their own attitudes and experiences, and to submit memories and photos of their time working, studying, volunteering or receiving care at U-M's medical campus and beyond. There are also activities for young visitors.\r\n\r\nThe museum is open to the public every Saturday and Sunday from 12 p.m. to 4 p.m.\r\n\r\nFull details about the exhibit, including parking instructions and how to book a free private group tour on a weekday, are available at http:\/\/michmed.org\/museum\r\n\r\nThe museum has an accessible entrance at the rear of the building.", "occurrence_notes":"Park in nearby municipal lots or structures; on-site parking is extremely limited. Accessible entrance at rear of building off Beakes St.", "guid":"139428-21885502@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/139428", "building_id":"", "building_name":"Off Campus Location", "building_official_id":null, "campus_maps_id":"1", "campus_maps_link_path":"", "campus_maps_link":"", "room":"", "location_name":"500 N. 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Dr. Zuchner's scientific interests lie in mapping disease genes and genomic variation that is related to disease.", "occurrence_notes":null, "guid":"143370-21892959@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/143370", "building_id":"1005037", "building_name":"Taubman Biomedical Science Research Building", "building_official_id":1005037, "campus_maps_id":"509", "campus_maps_link_path":"alfred-a-taubman-biomedical-science-research-bldg", "campus_maps_link":"https:\/\/maps.studentlife.umich.edu\/building\/alfred-a-taubman-biomedical-science-research-bldg", "room":"1020 Kahn Auditorium", "location_name":"Taubman Biomedical Science Research Building", "has_livestream":0, "cost":"", "tags":["Life Science"], "website":"https:\/\/medschool.umich.edu\/events?f%5B0%5D=series%3A13266", "links":[ { "type":"other", "url":"https:\/\/medschool.umich.edu\/events?f%5B0%5D=series%3A13266", "title":"Human Genetics Research Seminar Series" } ], "sponsors":[ { "group_name":"Department of Human Genetics", "group_id":"1137", "website":"" } ], "image_url":"", "image_description":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "qr_code_url":"http:\/\/events.umich.edu\/event\/143370\/qrcode.png", "occurrence_count":1, "first_occurrence":21892959 } , { "id":"147363-21900901", "datetime_modified":"20260402T143151", "datetime_start":"20260407T120000", "datetime_end":"20260407T125000", "has_end_time":1, "date_start":"2026-04-07", "date_end":"2026-04-07", "time_start":"12:00:00", "time_end":"12:50:00", "time_zone":"America\/Detroit", "event_title":"From Rooftop to Mercado: How CHASS Cultivates Food Access in a Healthcare Setting w\/Dr. Richard Bryce", "occurrence_title":"", "combined_title":"From Rooftop to Mercado: How CHASS Cultivates Food Access in a Healthcare Setting w\/Dr. Richard Bryce: Residents & Researchers Tuesday Talks on environment, health and community", "event_subtitle":"Residents & Researchers Tuesday Talks on environment, health and community", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"\u201cFrom Rooftop to Mercado: How CHASS Cultivates Food Access in a Healthcare Setting\u201d with Dr. Richard Bryce, the Chief Medical Officer of the Community Health and Social Services Center (CHASS). This series focuses on environment, health and community. We hope you can join us for the final Residents & Researchers webinar of the academic year. Organized by the Community Engagement Core (CEC) and the Integrated Health Sciences Core (IHSC) of the University of Michigan Lifestage Environmental Exposures and Disease Center (M-LEEaD). \n\nRegistration required https:\/\/myumi.ch\/3Rwd7", "occurrence_notes":"Registration required https:\/\/myumi.ch\/3Rwd7", "guid":"147363-21900901@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/147363", "building_id":"", "building_name":"Off Campus Location", "building_official_id":null, "campus_maps_id":"1", "campus_maps_link_path":"", "campus_maps_link":"", "room":"", "location_name":"Virtual", "has_livestream":1, "livestream_type":"other", "livetream_require_login":0, "livestream_id":"", "livestream_link":"", "cost":"", "tags":["Life Science"], "website":"", "links":[ ], "sponsors":[ { "group_name":"Michigan Lifestage Environmental Exposures and Disease Center", "group_id":"4335", "website":"https:\/\/twitter.com\/m_leead?lang=en" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/04\/event_147363_original-1.jpg", "image_description":"From Rooftop to Mercado: How CHASS Cultivates Food Access in a Healthcare Setting Richard Bryce, DO (Community Health And Social Services Center - CHASS) April 7 (Tuesday) 12-12:50 pm EST", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2026\/04\/event_147363_original-1.jpg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/04\/event_147363_original-1.jpg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2026\/04\/event_147363_original-1.jpg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2026\/04\/event_147363_original-1.jpg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2026\/04\/event_147363_original-1.jpg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2026\/04\/event_147363_original-1.jpg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2026\/04\/event_147363_original-1.jpg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2026\/04\/event_147363_original-1.jpg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2026\/04\/event_147363_original-1.jpg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2026\/04\/event_147363_original-1.jpg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2026\/04\/event_147363_original-1.jpg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2026\/04\/event_147363_original-1.jpg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2026\/04\/event_147363_original-1.jpg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2026\/04\/event_147363_original-1.jpg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2026\/04\/event_147363_original-1.jpg" }, "qr_code_url":"http:\/\/events.umich.edu\/event\/147363\/qrcode.png", "occurrence_count":1, "first_occurrence":21900901 } , { "id":"143699-21893661", "datetime_modified":"20260408T094420", "datetime_start":"20260408T160000", "datetime_end":"20260408T170000", "has_end_time":1, "date_start":"2026-04-08", "date_end":"2026-04-08", "time_start":"16:00:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"CCMB\/DCMB Weekly Seminar Series featuring Ting Wang, PhD (Professor of Medicine and Head, Department of Genetics WashU Medicine)", "occurrence_title":"", "combined_title":"CCMB\/DCMB Weekly Seminar Series featuring Ting Wang, PhD (Professor of Medicine and Head, Department of Genetics WashU Medicine)", "event_subtitle":"", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"CCMB\/DCMB Seminar by Ting Wang, PhD\n\n\"Unmasked: transposable elements as drivers and targets in cancer\"\n\nAbstract\n\nTransposable elements (TEs) represent almost half of the human genome. 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Keynote Speaker: Joseph C. Wu, M.D., Ph.D. Professor & Director, Stanford Cardiovascular Institute, Stanford University", "event_subtitle":"Keynote Speaker: Joseph C. Wu, M.D., Ph.D. Professor & Director, Stanford Cardiovascular Institute, Stanford University", "event_type":"Conference \/ Symposium", "event_type_id":"5", "description":"Please join us for the upcoming Annual Michigan Pioneer Fellows Symposium, when we will celebrate the invaluable research contributions of postdoctoral fellows and highlight the innovative work being done by Pioneer Fellows and other postdoctoral researchers across the University of Michigan. \n\nRegistration is open through April 20! \nPoster abstract submission is now closed.\n\n2026 Michigan Pioneer Fellows Symposium:\n1:00\u20136:00 p.m., April 23, 2026\nBSRB Kahn Auditorium\n\nSchedule:\n1:00 Welcome and introductions\n1:05 Talks by Pioneer Fellows\n3:30 Keynote address: \u201cNew Approach Methodologies (NAMs) to Accelerate Clinical Trials in a Dish (CTiD),\u201d Joseph C. Wu, M.D., Ph.D. Professor & Director, Stanford Cardiovascular Institute, Stanford University\n4:30 Poster session\n5:30 Concluding remarks and reception\n\nAbstract:\nDrug discovery and development continue to face significant challenges, with over 90% of candidate drugs failing in clinical trials. These efficacy failures are primarily due to inherent species-specific differences, fundamental biological variances between model organisms and humans, and the limitations of existing models to accurately reflect the complexity of human disease and treatment responses. In this discussion, I will explore how the NIH and FDA are advocating for new alternative methodologies (NAMs) to reduce or replace animal testing. I will highlight recent advancements in technologies such as stem cells, organoids, and microphysiological systems (MPS), along with the roles of clinical genomics and AI\/ML. Additionally, I will examine how these platforms can collaboratively enhance our understanding of rare orphan diseases, facilitate drug discovery, support precision medicine, and enable clinical trials in a dish (CTiD).\n\nAbout the Speaker:\nJoseph C. Wu, MD, PhD is Director of Stanford Cardiovascular Institute and Simon H. Stertzer, MD, Professor of Medicine and Radiology at Stanford University. Dr. Wu received his MD from Yale University and PhD (Molecular & Medical Pharmacology) at University of California, Los Angeles. He is board certified in cardiovascular medicine. His lab works on genomics, stem cells\/organoids, AI\/ML, and drug discovery. The main goals are to (i) understand basic disease mechanisms, (ii) implement precision medicine for patients, and (iii) accelerate drug discovery via \u201cnew alternative methodologies\u201d (NAMs) and \u201cclinical trial in a dish\u201d (CTiD) concept. Dr. Wu has published >700 manuscripts with H-index of 147 on Google scholar. 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During this time, patterns of brain development and life history changed to triple the number of neurons produced prenatally, extend synaptic plasticity through a prolonged phase of development, and restructure connectivity between brain regions. At the same time tens of millions of mutations accumulated as fixed changes in the human genome through the processes of selection and drift. A portion of this new genomic information guides the development of uniquely human traits and contributes to disease vulnerabilities shared by all humans. However, connecting human-specific mutations to recently evolved traits remains a major challenge because we lack experimental systems for comparative and functional studies of great ape cortical development. To identify genomic differences underlying unique features or vulnerabilities of the human brain, we are incorporating advances in single cell genomics and genome engineering with great ape cerebral organoid models of brain development. We are enthusiastic for new graduate students to join the team, and the lab is well suited for those with an interest in evolution, neuropsychiatric disorders, neuronal cell diversity, stem cell models, or bioinformatics.", "occurrence_notes":null, "guid":"143397-21893075@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/143397", "building_id":"1005037", "building_name":"Taubman Biomedical Science Research Building", "building_official_id":1005037, "campus_maps_id":"509", "campus_maps_link_path":"alfred-a-taubman-biomedical-science-research-bldg", "campus_maps_link":"https:\/\/maps.studentlife.umich.edu\/building\/alfred-a-taubman-biomedical-science-research-bldg", "room":"1020 Kahn Auditorium", "location_name":"Taubman Biomedical Science Research Building", "has_livestream":0, "cost":"", "tags":["Life Science"], "website":"https:\/\/medschool.umich.edu\/events?f%5B0%5D=series%3A13266", "links":[ { "type":"other", "url":"https:\/\/medschool.umich.edu\/events?f%5B0%5D=series%3A13266", "title":"Human Genetics Research Seminar Series" } ], "sponsors":[ { "group_name":"Department of Human Genetics", "group_id":"1137", "website":"" } ], "image_url":"", "image_description":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "qr_code_url":"http:\/\/events.umich.edu\/event\/143397\/qrcode.png", "occurrence_count":1, "first_occurrence":21893075 } , { "id":"139428-21899852", "datetime_modified":"20260324T094536", "datetime_start":"20260509T120000", "datetime_end":"20260509T160000", "has_end_time":1, "date_start":"2026-05-09", "date_end":"2026-05-09", "time_start":"12:00:00", "time_end":"16:00:00", "time_zone":"America\/Detroit", "event_title":"Creating the Future of Medicine for 175 Years", "occurrence_title":"", "combined_title":"Creating the Future of Medicine for 175 Years: A free museum exhibit about U-M medical history", "event_subtitle":"A free museum exhibit about U-M medical history", "event_type":"Exhibition", "event_type_id":"7", "description":"As the Medical School celebrates the anniversary of its opening in the fall of 1850, and Michigan Medicine marks the 100th anniversary of the opening of the \"Old Main\" University Hospital that served as its flagship from 1925 to 1986, a free museum exhibit explores 175 years of medical education, research and clinical care. \r\n\r\nOpen to the public at the Museum on Main Street operated by the Washtenaw County Historical Society, the exhibit includes artifacts, photos and facts about how U-M's medical community grew from humble beginnings on the Diag to become one of the nation's largest and most respected academic medical centers. 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For a summary of our major research foci, see Research.\r\n\r\nOur group is located in the Bakar Computational Health Sciences Institute and the Department of Epidemiology and Biostatistics at the University of California, San Francisco. Prior to coming to UCSF, Tony spent 7 wonderful years at Vanderbilt University.\r\n\r\nHumans differ from one another and our closest living relatives, the chimpanzees, in a wide range of traits, including our susceptibility to many diseases. We model the evolutionary processes that have produced these novel traits and develop algorithms that compare genomes to predict the functional relevance of specific genetic differences between individuals and species.", "occurrence_notes":null, "guid":"143393-21893074@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/143393", "building_id":"1005037", "building_name":"Taubman Biomedical Science Research Building", "building_official_id":1005037, "campus_maps_id":"509", "campus_maps_link_path":"alfred-a-taubman-biomedical-science-research-bldg", "campus_maps_link":"https:\/\/maps.studentlife.umich.edu\/building\/alfred-a-taubman-biomedical-science-research-bldg", "room":"1020 Kahn Auditorium", "location_name":"Taubman Biomedical Science Research Building", "has_livestream":0, "cost":"", "tags":["Life Science"], "website":"https:\/\/medschool.umich.edu\/events?f%5B0%5D=series%3A13266", "links":[ { "type":"other", "url":"https:\/\/medschool.umich.edu\/events?f%5B0%5D=series%3A13266", "title":"Human Genetics Research Seminar Series" } ], "sponsors":[ { "group_name":"Department of Human Genetics", "group_id":"1137", "website":"" } ], "image_url":"", "image_description":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "qr_code_url":"http:\/\/events.umich.edu\/event\/143393\/qrcode.png", "occurrence_count":1, "first_occurrence":21893074 } , { "id":"147692-21901602", "datetime_modified":"20260415T213002", "datetime_start":"20260512T090000", "datetime_end":"20260512T170000", "has_end_time":1, "date_start":"2026-05-12", "date_end":"2026-05-12", "time_start":"09:00:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"Saltiel Life Sciences Symposium 2026", "occurrence_title":"", "combined_title":"Saltiel Life Sciences Symposium 2026: Decoding GLP-1s: The science and circuitry behind new anti-obesity drugs", "event_subtitle":"Decoding GLP-1s: The science and circuitry behind new anti-obesity drugs", "event_type":"Conference \/ Symposium", "event_type_id":"5", "description":"The 2026 Saltiel Life Sciences Symposium will explore the basic science behind the new generation of GLP-1 therapeutics targeting diabetes and obesity. Speakers will describe the discoveries and fundamental cellular mechanisms behind the drugs, as well as ongoing efforts to improve them.\n\n*Schedule:*\n\n9:05 a.m. | Welcome\nRoger Cone, Ph.D. \nMary Sue Coleman Director, Life Sciences Institute; Tadataka Yamada Distinguished University Professor of Molecular and Integrative Physiology, Medical School; Professor of Molecular, Cellular, and Developmental Biology, College of Literature, Science, and the Arts, University of Michigan\n\n9:15 a.m. | Research talk\nRandy Seeley, Ph.D.\nHenry King Ransom Professor of Surgery, Professor of Surgery and Internal Medicine, Medical School; Professor of Nutritional Sciences, School of Public Health, University of Michigan\n\n9:55 a.m. | Research talk\nAmber Alhadeff, Ph.D.\nAssociate Professor of Neuroscience, Monell Chemical Senses Center, University of Pennsylvania\n\n10:35 a.m. | Morning break\n\n10:50 a.m. | Research talk\nMartin Myers, M.D., Ph.D.\nMarilyn H Vincent Professor of Diabetes Research, Professor of Internal Medicine and of Molecular & Integrative Physiology, Medical School, University of Michigan\n\n11:30 a.m. | Research talk\nKevin Williams, Ph.D.\nAssociate Professor of Internal Medicine, UT Southwestern Medical Center\n\n12:10 p.m. | Lunch break\n\n1:10 p.m. | Research talk\nTune Pers, Ph.D.\nAssociate Professor and Program Coordinator, Human Variation & Functional Genomics, Novo Nordisk Foundation Center for Basic Metabolic Research\n\n1:50 p.m. | Research talk\nTimo M\u00fcller, Ph.D.\nDirector, Institute for Diabetes and Obesity; W3 Professor, Walther-Straub Institute for Pharmacology and Toxicology; Medical Faculty, Ludwig-Maximilians-University Munich\n\n2:30 p.m. | Poster session \n\n3:45 p.m. | Introduction of the Mary Sue and Kenneth Coleman Lecturer\nThomas Wang, M.D.\nDean and Josiah Macy, Jr. Professor, Medical School; Chief Academic Office, Michigan Medicine, University of Michigan\n\n3:50 p.m. | Mary Sue and Kenneth Coleman Life Sciences 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