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Ortega", "event_subtitle":"\"From Concept to Care: Leading R&D and Operations in the Medical Device Industry,\" with Carlos M. Ortega", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"From Concept to Care: Leading R&D and Operations in the Medical Device Industry\nAbstract:\nThis seminar focuses on the career journey and real-world experiences of a Vice President of R&D and Operations Engineering in the medical device industry. Students will gain insight into how careers evolve across engineering, innovation, operations, and leadership, and what skills, mindsets, and decisions enable long-term success. The session offers practical guidance on navigating industry roles, learning from early career choices, and building a path at the intersection of engineering, healthcare, and business impact.\n\nBio:\nWith more than 25 years in the medical device industry, Carlos M. Ortega (Vice President of R&D and Operations Engineering) has built a career at the intersection of innovation, engineering execution, and clinical impact. Having held leadership and functional roles at companies such as Terumo, Medtronic, and Johnson & Johnson, he has contributed to the development and commercialization of technologies across cardiovascular, neurovascular, aortic, and peripheral vascular therapies.\n\nHis experience spans predominantly R&D leadership, complemented by roles in operations engineering and product marketing, giving him a unique perspective on how ideas translate into manufacturable, clinically meaningful products. Throughout his career, he has led multidisciplinary teams, navigated complex regulatory environments, and helped organizations align technology development with patient and business needs.\n\nHe is passionate about the impact medical devices have on the lives or the patients they serve and in mentoring the next generation of professionals by sharing practical insights into building impactful careers in the medical device industry.", "occurrence_notes":"https:\/\/umich.zoom.us\/j\/94337625486", "guid":"145043-21896577@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/145043", "building_id":"1000406", "building_name":"Lurie Biomedical Engineering (formerly ATL)", "building_official_id":1000406, "campus_maps_id":"7", "campus_maps_link_path":"lurie-ann-and-robert-h-biomedical-engineering-bld", "campus_maps_link":"https:\/\/maps.studentlife.umich.edu\/building\/lurie-ann-and-robert-h-biomedical-engineering-bld", "room":"1130", "location_name":"Lurie Biomedical Engineering (formerly ATL)", "has_livestream":0, "cost":"", "tags":["biomedical engineering"], "website":"http:\/\/bme.umich.edu", "links":[ { "type":"other", "url":"http:\/\/bme.umich.edu", "title":null } ], "sponsors":[ { "group_name":"Biomedical Engineering", "group_id":"1143", "website":"https:\/\/www.facebook.com\/profile.php?id=100094127215673" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/02\/event_145043_original-1.jpg", "image_description":"A speaker talking to a group of students in a classroom.", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_thumb\/media\/attachments\/2026\/02\/event_145043_original-1.jpg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/02\/event_145043_original-1.jpg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_2x\/media\/attachments\/2026\/02\/event_145043_original-1.jpg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2026\/02\/event_145043_original-1.jpg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2026\/02\/event_145043_original-1.jpg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2026\/02\/event_145043_original-1.jpg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2026\/02\/event_145043_original-1.jpg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2026\/02\/event_145043_original-1.jpg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2026\/02\/event_145043_original-1.jpg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2026\/02\/event_145043_original-1.jpg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2026\/02\/event_145043_original-1.jpg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2026\/02\/event_145043_original-1.jpg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2026\/02\/event_145043_original-1.jpg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_large\/media\/attachments\/2026\/02\/event_145043_original-1.jpg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2026\/02\/event_145043_original-1.jpg" }, "qr_code_url":"http:\/\/events.umich.edu\/event\/145043\/qrcode.png", "occurrence_count":1, "first_occurrence":21896577 } , { "id":"144925-21896158", "datetime_modified":"20260202T132529", "datetime_start":"20260217T100000", "datetime_end":"20260217T110000", "has_end_time":1, "date_start":"2026-02-17", "date_end":"2026-02-17", "time_start":"10:00:00", "time_end":"11:00:00", "time_zone":"America\/Detroit", "event_title":"Careers in the Biosciences (Virtual Panel)", "occurrence_title":"", "combined_title":"Careers in the Biosciences (Virtual Panel)", "event_subtitle":"", "event_type":"Livestream \/ Virtual", "event_type_id":"24", "description":"University of Michigan staff discuss their career paths, including graduate\/medical training, academic\/industry research, consulting, and teaching.\n\nVirtual panel - 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The excessive zeros and compositionality of metagenomics data are two main challenges for differential abundance analysis. We propose a novel method called \u201canalysis of differential abundance by pooling Tobit models\u201d (ADAPT) to overcome these two challenges. ADAPT uniquely treats zero counts as left-censored observations to facilitate computation and enhance interpretation. ADAPT also encompasses a theoretically justified way of selecting non-differentially abundant microbiome taxa as a reference for hypothesis testing. We generate synthetic data using independent simulation frameworks to show that ADAPT has more consistent false discovery rate control and higher statistical power than competitors. We use ADAPT to analyze 16S rRNA sequencing of saliva samples and shotgun metagenomics sequencing of plaque samples collected from infants in the COHRA2 study. The results provide novel insights into the association between the oral microbiome and early childhood dental caries.\r\n\r\nAbout the DCMB Tools & Technology Seminar Series\r\n\r\nThe DCMB Tools and Technology Seminar Series is held in Medical Science Building 1 (MS1), Room 4B700, each Thursday at 12pm EST. Each seminar highlights a computational tool, technology, or methodology that is under development or in current use and is of special interest to DCMB and University researchers. Presenters are U-M researchers and students.\r\n\r\nThese seminars are live-streamed and recorded and made available for future viewing via the DCMB YouTube ChannelAbout the DCMB Tools & Technology Seminar Series\r\n\r\nThe DCMB Tools and Technology Seminar Series is held in Medical Science Building 1 (MS1), Room 4B700, each Thursday at 12pm EST. Each seminar highlights a computational tool, technology, or methodology that is under development or in current use and is of special interest to DCMB and University researchers. 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This seminar will present recent technological advances in ultrasound to improve both imaging performance and therapeutic capability.\n\nThe first part of the seminar will introduce transcranial histotripsy as a non-invasive brain therapy. Histotripsy is a non-thermal, non-ionizing ultrasound therapy that mechanically fractionates target tissue through acoustic cavitation generated by short, high-intensity ultrasound pulses. Transcranial histotripsy is particularly challenging because the intact human skull introduces severe attenuation and phase aberration. This seminar will discuss the specialized instrumentation for transcranial histotripsy, methods to ensure precise targeting and real-time monitoring (including skull aberration correction and cavitation imaging), and feasibility and safety evaluation of transcranial histotripsy in preclinical studies.\n\nThe second half of the seminar will focus on ultrafast ultrasound imaging using large-aperture arrays. By combining ultrafast acquisition techniques with parallel computing, this approach enables high-resolution volumetric imaging over a large field of view at video-rate frame rates. Two clinically relevant applications will be presented: panoramic spine imaging for diagnosis and interventional guidance, and breast ultrasound tomography for early cancer screening. Finally, we will discuss remaining technical challenges for clinical translation and highlight how advances in ultrafast imaging can be integrated with histotripsy to enable safer, more precise therapies.\n\nBio:\nDr. Ning Lu is a Senior Ultrasound Engineer at United Imaging Healthcare North America in Bellevue, Washington. She completed her postdoctoral training in the Department of Radiology at Stanford University under the mentorship of Prof. Katherine W. Ferrara, where she developed high-resolution 3D ultrasound imaging techniques for diagnostic and interventional guidance. Dr. Lu received her Ph.D. in Biomedical Engineering and Scientific Computing (joint degree) from the University of Michigan in 2023, working with Prof. Zhen Xu on MR-guided transcranial histotripsy for non-invasive brain therapy. Her research interests include biomedical ultrasound, medical instrumentation, parallel computing, and AI-driven imaging science. 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Before joining the faculty at University of Cincinnati in 2024, she was an Associate Professor at Mississippi State University (2013 \u2013 2023) and she trained as a postdoctoral research associate at Rice University in the Department of Bioengineering. Dr. Hendrix received all her educational training at Clemson University with a B.S. in Biochemistry, M.S., and Ph.D. In Bioengineering. Dr. Hendrix\u2019s research interests include vascular calcification, smooth muscle cells, cell and gene therapy, and mechanotransduction. Her work has been funded by the National Science Foundation (NSF), the National Institutes of Health (NIH), and the United States Department of Agriculture (USDA).\n\nIn addition to her passion for vascular research, Dr. Hendrix is a student advocate and a champion for diversity and inclusion. She has worked to create inclusive spaces for trainee development and success. 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autoimmunity and cancer,\" with Cory Berkland, Ph.D.", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Engineering immunotherapies for autoimmunity and cancer\n\nAbstract:\nEffective delivery of drugs to direct immune responses requires an understanding of biological barriers, physicochemical properties of drug molecules, formulation and transport in vivo. Designing molecular structures that persist at the administration site or that promote drainage to regional lymphatic networks may enhance immune responses while sparing immune-related adverse events. Here, drug transport and local elimination mechanisms will be overviewed. Then, examples of molecular designs to direct drug delivery will be presented. Autoimmune therapies were designed by our lab to promote the drainage of autoantigens to secondary lymphoid organs to treat autoimmune diseases. Specifically, the size and solubility of these molecular constructs were tuned to promote access to the lymphatic compartment and induce immune tolerance in mouse models of type 1 diabetes. Our lab has also recently explored the design of immunostimulants that persist in tumor tissue after intratumoral\/perilesional injection. Intratumoral immunotherapy is proposed to work synergistically with checkpoint inhibitors making a nonresponsive \u2018cold\u2019 tumor \u2018hot\u2019 by recruiting and activating tumor infiltrating lymphocytes. This approach can suffer from systemic immune-related adverse reactions, however, if enough immunostimulant escapes the site of administration. Data on the use of electrostatic mechanisms to promote tumor retention will be presented. These examples underscore the need for rational design of drug molecules or formulations based upon the route of delivery and biological barriers encountered. \n\nBio:\nCory Berkland is the Mark and Becky Levin Professor in the Departments of Biomedical Engineering and Chemistry at Washington University in Saint Louis. Previously, he was the Solon E. Summerfield Professor in the Department of Pharmaceutical Chemistry and in the Department of Chemical Engineering at The University of Kansas. He received MS and PhD degrees from the Department of Chemical and Biomolecular Engineering at the University of Illinois in Urbana-Champaign and a BS degree in Chemical Engineering from Iowa State University in Ames. His lab studies pharmaceuticals and materials with an emphasis on molecular design and transport in the human body. He is a co-founder of Orbis Biosciences (acquired by Adare Pharmaceuticals), Savara Pharmaceuticals (NASDAQ:SVRA), Bond Biosciences, Kinimmune, Axioforce, and other start-ups. He has served as a board member, executive, and fundraiser for these companies.", "occurrence_notes":"https:\/\/umich.zoom.us\/j\/94337625486", "guid":"145728-21897738@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/145728", "building_id":"1000406", "building_name":"Lurie Biomedical Engineering (formerly ATL)", "building_official_id":1000406, "campus_maps_id":"7", "campus_maps_link_path":"lurie-ann-and-robert-h-biomedical-engineering-bld", "campus_maps_link":"https:\/\/maps.studentlife.umich.edu\/building\/lurie-ann-and-robert-h-biomedical-engineering-bld", "room":"1130", "location_name":"Lurie Biomedical Engineering (formerly ATL)", "has_livestream":0, "cost":"", "tags":["biomedical engineering"], "website":"http:\/\/bme.umich.edu", "links":[ { "type":"other", "url":"http:\/\/bme.umich.edu", "title":null } ], "sponsors":[ { "group_name":"Biomedical Engineering", "group_id":"1143", "website":"https:\/\/www.facebook.com\/profile.php?id=100094127215673" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/02\/event_145728_original-1.jpg", "image_description":"A speaker talking to a group of students in a classroom.", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2026\/02\/event_145728_original-1.jpg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/02\/event_145728_original-1.jpg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2026\/02\/event_145728_original-1.jpg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2026\/02\/event_145728_original-1.jpg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2026\/02\/event_145728_original-1.jpg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2026\/02\/event_145728_original-1.jpg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2026\/02\/event_145728_original-1.jpg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2026\/02\/event_145728_original-1.jpg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2026\/02\/event_145728_original-1.jpg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2026\/02\/event_145728_original-1.jpg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2026\/02\/event_145728_original-1.jpg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2026\/02\/event_145728_original-1.jpg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2026\/02\/event_145728_original-1.jpg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2026\/02\/event_145728_original-1.jpg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2026\/02\/event_145728_original-1.jpg" }, "qr_code_url":"http:\/\/events.umich.edu\/event\/145728\/qrcode.png", "occurrence_count":1, "first_occurrence":21897738 } , { "id":"146126-21898419", "datetime_modified":"20260310T135950", "datetime_start":"20260317T160000", "datetime_end":"20260317T180000", "has_end_time":1, "date_start":"2026-03-17", "date_end":"2026-03-17", "time_start":"16:00:00", "time_end":"18:00:00", "time_zone":"America\/Detroit", "event_title":"The Future of Health AI", "occurrence_title":"", "combined_title":"The Future of Health AI: Keynote and Fireside Discussion", "event_subtitle":"Keynote and Fireside Discussion", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"Join industry and startup leaders as they break down how AI is transforming healthcare now and where it\u2019s headed next. 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Featuring David Rhew, MD, Chief Medical Officer at Microsoft, and Jim Mault, MD, Founder and chairman of Biointellisense. Text reads: Join industry and startup leaders as they break down how AI is transforming healthcare now and where it's headed next. Match 17, 2026 from 4pm to 6pm. Ross School of Business, Robertson Auditorium. Sponsors include Zell Lurie Institute, Pinkert Healthcare Accelerator, Michigan Biomedical Venture Fund, Center for Entrepreneurship.", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2026\/03\/event_146126_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/03\/event_146126_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2026\/03\/event_146126_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2026\/03\/event_146126_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2026\/03\/event_146126_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2026\/03\/event_146126_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2026\/03\/event_146126_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2026\/03\/event_146126_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2026\/03\/event_146126_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2026\/03\/event_146126_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2026\/03\/event_146126_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2026\/03\/event_146126_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2026\/03\/event_146126_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2026\/03\/event_146126_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2026\/03\/event_146126_original-1.png" }, "qr_code_url":"http:\/\/events.umich.edu\/event\/146126\/qrcode.png", "occurrence_count":1, "first_occurrence":21898419 } , { "id":"146152-21898595", "datetime_modified":"20260313T155924", "datetime_start":"20260319T150000", "datetime_end":"20260319T160000", "has_end_time":1, "date_start":"2026-03-19", "date_end":"2026-03-19", "time_start":"15:00:00", "time_end":"16:00:00", "time_zone":"America\/Detroit", "event_title":"Biomedical Engineering (BME 500) Seminar Series", "occurrence_title":"", "combined_title":"Biomedical Engineering (BME 500) Seminar Series: \"Patterned Biomaterials: New Tools to Probe and Control Complex Biological Systems,\" with Jouha Min, Ph.D.", "event_subtitle":"\"Patterned Biomaterials: New Tools to Probe and Control Complex Biological Systems,\" with Jouha Min, Ph.D.", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Patterned Biomaterials: New Tools to Probe and Control Complex Biological Systems\n\nAbstract:\nEngineered materials and molecular sensing tools are transforming how we study and control complex biological systems. Yet many technologies operate at a single scale\u2014either manipulating cellular environments without molecular precision or profiling molecular signals without spatial or mechanical context. My lab addresses this challenge through chemical and materials innovation, developing scalable platforms that integrate molecular design with quantitative analysis. We focus on two complementary directions: (1) physico-chemical design of soft interfaces with tunable nanoscale architecture and dynamic mechanics to probe and control material\u2013biology interactions, and (2) biomolecular sensing platforms that combine polymer chemistry, optical or electrochemical detection, and data-driven analysis for accessible diagnostics. In this talk, I will highlight two representative efforts: nature-inspired nanopatterned coatings with dynamically tunable surface topography for long-term antibacterial activity, and integrated bioanalytical sensing technologies for early, point-of-care detection of sepsis. \n\nBio:\nDr. Jouha Min is an Assistant Professor in the Department of Chemical Engineering at University of Michigan. She received her B.S. in Chemical Engineering from Cornell University in 2010 and her Ph.D. in Chemical Engineering from MIT, where she was advised by Paula Hammond and Richard Braatz. She conducted her postdoctoral research with Ralph Weissleder at Harvard Medical School and Massachusetts General Hospital, where she worked at the interface of engineering, biology, and clinical translation. Dr. Min\u2019s research group applies core principles of chemical and biological engineering\u2014including transport phenomena, reaction kinetics, materials synthesis, and systems-level analysis\u2014to develop new methodologies for probing and controlling material\u2013biology interactions across three-dimensional space and time. Her work aims to establish a quantitative and mechanistic foundation for transformative advances in disease diagnosis, treatment, and prevention. She is the recipient of several honors, including the NSF CAREER Award (2025), the NIH R35 MIRA Award (2025), and the V Foundation V Scholar Award (2023).", "occurrence_notes":"https:\/\/umich.zoom.us\/j\/94337625486", "guid":"146152-21898595@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/146152", "building_id":"1000406", "building_name":"Lurie Biomedical Engineering (formerly ATL)", "building_official_id":1000406, "campus_maps_id":"7", "campus_maps_link_path":"lurie-ann-and-robert-h-biomedical-engineering-bld", "campus_maps_link":"https:\/\/maps.studentlife.umich.edu\/building\/lurie-ann-and-robert-h-biomedical-engineering-bld", "room":"1130", "location_name":"Lurie Biomedical Engineering (formerly ATL)", "has_livestream":0, "cost":"", "tags":["biomedical engineering"], "website":"http:\/\/bme.umich.edu", "links":[ { "type":"other", "url":"http:\/\/bme.umich.edu", "title":null } ], "sponsors":[ { "group_name":"Biomedical Engineering", "group_id":"1143", 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