{ "37328-6502173": { "datetime_modified":"20170105T143903", "datetime_start":"20170512T080000", "datetime_end":"20170512T200000", "has_end_time":1, "date_start":"2017-05-12", "date_end":"2017-05-12", "time_start":"08:00:00", "time_end":"20:00:00", "time_zone":"America\/Detroit", "event_title":"The Grandmother Tree Walk", "occurrence_title":"", "combined_title":"The Grandmother Tree Walk", "event_subtitle":"", "event_type":"Exhibition", "event_type_id":"7", "description":"Matthaei Botanical Gardens & Nichols Arboretum celebrates the University of Michigan bicentennial with a tour of 12 historic trees in the Arboretum. The bicentennial story is told from the perspective of the trees, and key moments of U-M's people and history that occurred during the trees' long lives are revealed. Visitors may pick up a map at the Arb visitor center to take this easy, self-guided tour.", "occurrence_notes":null, "guid":"37328-6502173@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/37328", "building_id":"1000005", "building_name":"Nichols Arboretum", "campus_maps_id":"555", "room":"", "location_name":"Nichols Arboretum", "has_livestream":0, "cost":"", "tags":["Free","Bicentennial","Environment","Outdoors","umich200"], "website":"", "sponsors":[ { "group_name":"Matthaei Botanical Gardens & Nichols Arboretum", "group_id":"1072", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2017\/01\/event_37328_original.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2017\/01\/event_37328_original.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2017\/01\/event_37328_original.jpeg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2017\/01\/event_37328_original.jpeg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2017\/01\/event_37328_original.jpeg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2017\/01\/event_37328_original.jpeg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2017\/01\/event_37328_original.jpeg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2017\/01\/event_37328_original.jpeg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2017\/01\/event_37328_original.jpeg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2017\/01\/event_37328_original.jpeg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2017\/01\/event_37328_original.jpeg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2017\/01\/event_37328_original.jpeg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2017\/01\/event_37328_original.jpeg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2017\/01\/event_37328_original.jpeg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2017\/01\/event_37328_original.jpeg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2017\/01\/event_37328_original.jpeg" }, "occurrence_count":181, "first_occurrence":6502134 } , "37210-6457654": { "datetime_modified":"20170104T172727", "datetime_start":"20170512T080000", "datetime_end":"20170512T190000", "has_end_time":1, "date_start":"2017-05-12", "date_end":"2017-05-12", "time_start":"08:00:00", "time_end":"19:00:00", "time_zone":"America\/Detroit", "event_title":"The Student Experience: Flappers, Mappers, and the Fight for Equality on Campus", "occurrence_title":"", "combined_title":"The Student Experience: Flappers, Mappers, and the Fight for Equality on Campus", "event_subtitle":"", "event_type":"Exhibition", "event_type_id":"7", "description":"Join flappers as they stroll through 1926 Ann Arbor with a beautiful pictorial map and experience the busy student life of the 1920s, celebrate two University of Michigan alumna who have greatly influenced the field of cartography, and explore the rise of diversity and the fight for equality on campus through protest posters from the Joseph A. Labadie Collection of the U-M Library\u2019s Special Collections.", "occurrence_notes":null, "guid":"37210-6457654@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/37210", "building_id":"1000181", "building_name":"Hatcher Graduate Library", "campus_maps_id":"65", "room":"Clark Library (2nd Floor Hatcher)", "location_name":"Hatcher Graduate Library", "has_livestream":0, "cost":"", "tags":["Bicentennial","Exhibition","Free","Library"], "website":"", "sponsors":[ { "group_name":"University Library", "group_id":"1186", "website":"https:\/\/www.facebook.com\/UMichLibrary\/" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2017\/01\/event_37210_original.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2017\/01\/event_37210_original.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2017\/01\/event_37210_original.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2017\/01\/event_37210_original.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2017\/01\/event_37210_original.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2017\/01\/event_37210_original.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2017\/01\/event_37210_original.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2017\/01\/event_37210_original.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2017\/01\/event_37210_original.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2017\/01\/event_37210_original.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2017\/01\/event_37210_original.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2017\/01\/event_37210_original.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2017\/01\/event_37210_original.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2017\/01\/event_37210_original.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2017\/01\/event_37210_original.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2017\/01\/event_37210_original.png" }, "occurrence_count":172, "first_occurrence":6457656 } , "40756-8741792": { "datetime_modified":"20170501T173118", "datetime_start":"20170512T083000", "datetime_end":"20170512T180000", "has_end_time":1, "date_start":"2017-05-12", "date_end":"2017-05-12", "time_start":"08:30:00", "time_end":"18:00:00", "time_zone":"America\/Detroit", "event_title":"Storied Acquisitions: Highlights from the University of Michigan Library Collections", "occurrence_title":"", "combined_title":"Storied Acquisitions: Highlights from the University of Michigan Library Collections", "event_subtitle":"", "event_type":"Exhibition", "event_type_id":"7", "description":"In celebration of the university\u2019s bicentennial, this exhibit showcases treasures from a variety of library collecting areas and explores the stories behind the development of some of our most distinctive collections. From Audubon\u2019s Birds of America, the first book acquired for the library, to more recent arrivals like Robert Altman\u2019s Academy Award, the items on display afford us an opportunity to reflect on the history and consider the future of one of the country's largest and most important research library collections.\r\n\r\nThe exhibit features books, maps, sheet music, manuscripts, and artifacts from the University of Michigan Library\u2019s Art, Architecture, and Engineering Library; Clark Library; Music Library; and Special Collections Library.\r\n\r\nHours: Weekdays 8:30am-6pm, Saturdays 10am-6pm, Sundays 1-6 pm \r\nClosed: May 27-29, July 1-2, July 4, August 19-20, August 26-27", "occurrence_notes":null, "guid":"40756-8741792@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/40756", "building_id":"1000181", "building_name":"Hatcher Graduate Library", "campus_maps_id":"65", "room":"Audubon Room", "location_name":"Hatcher Graduate Library", "has_livestream":0, "cost":"", "tags":["Exhibition","Library"], "website":"https:\/\/www.lib.umich.edu\/events\/storied-acquisitions-highlights-university-michigan-library-collections", "sponsors":[ { "group_name":"University Library", "group_id":"1186", "website":"https:\/\/www.facebook.com\/UMichLibrary\/" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2017\/05\/event_40756_original.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_thumb\/media\/attachments\/2017\/05\/event_40756_original.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2017\/05\/event_40756_original.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_2x\/media\/attachments\/2017\/05\/event_40756_original.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2017\/05\/event_40756_original.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2017\/05\/event_40756_original.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2017\/05\/event_40756_original.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2017\/05\/event_40756_original.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large_lightbox\/media\/attachments\/2017\/05\/event_40756_original.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2017\/05\/event_40756_original.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2017\/05\/event_40756_original.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2017\/05\/event_40756_original.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2017\/05\/event_40756_original.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2017\/05\/event_40756_original.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2017\/05\/event_40756_original.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2017\/05\/event_40756_original.png" }, "occurrence_count":104, "first_occurrence":8741788 } , "40477-8576027": { "datetime_modified":"20170411T110307", "datetime_start":"20170512T084500", "datetime_end":"20170512T164500", "has_end_time":1, "date_start":"2017-05-12", "date_end":"2017-05-12", "time_start":"08:45:00", "time_end":"16:45:00", "time_zone":"America\/Detroit", "event_title":"Banner Moments: The National Anthem in American Life", "occurrence_title":"", "combined_title":"Banner Moments: The National Anthem in American Life", "event_subtitle":"", "event_type":"Exhibition", "event_type_id":"7", "description":"The new Ford Presidential Library lobby exhibit, curated by University of Michigan musicologist Mark Clague, illustrates through interpretive panels, historical documents and photographs, the cultural 200-year history of \u201cThe Star-Spangled Banner\u201d (1814\u20132014). The tale that emerges demonstrates the power of music and poetry to spark the social imagination and thus create a sense of shared community.\r\n\r\nInspired by the successful defense of Baltimore, Maryland from British attack in September 1814, lawyer and amateur poet Francis Scott Key penned his now famous lyric. Rather than extraordinary, Key\u2019s creative impulse was typical of early America\u2019s broadside ballad tradition in which new words were written to fit well known tunes. The result, however, was far from everyday\u2014Key could not have predicted that his song would survive the moment, yet become his nation\u2019s singular anthem.\r\n\r\nFollow the \u201cThe Star-Spangled Banner\u201d from the moments leading up to September 14, 1814 through the present day and explore the social history of our national song.\r\nMarch 2017 to September 2017 \r\n\r\nMonday - Friday. 8:45 am - 4:45 pm\r\nClosed all Federal holidays.", "occurrence_notes":"Monday - Friday. 8:45 am - 4:45 pm. Closed Federal Holidays", "guid":"40477-8576027@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/40477", "building_id":"1000446", "building_name":"Gerald Ford Library", "campus_maps_id":"62", "room":"", "location_name":"Gerald Ford Library", "has_livestream":0, "cost":"", "tags":["Star Spangled Banner","Music History"], "website":"", "sponsors":[ { "group_name":"Gerald R. Ford Presidential Library", "group_id":"1114", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2017\/04\/event_40477_original.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_thumb\/media\/attachments\/2017\/04\/event_40477_original.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2017\/04\/event_40477_original.jpeg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_2x\/media\/attachments\/2017\/04\/event_40477_original.jpeg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2017\/04\/event_40477_original.jpeg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2017\/04\/event_40477_original.jpeg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2017\/04\/event_40477_original.jpeg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2017\/04\/event_40477_original.jpeg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large_lightbox\/media\/attachments\/2017\/04\/event_40477_original.jpeg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2017\/04\/event_40477_original.jpeg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2017\/04\/event_40477_original.jpeg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2017\/04\/event_40477_original.jpeg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2017\/04\/event_40477_original.jpeg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2017\/04\/event_40477_original.jpeg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2017\/04\/event_40477_original.jpeg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2017\/04\/event_40477_original.jpeg" }, "occurrence_count":128, "first_occurrence":8575955 } , "40853-8807870": { "datetime_modified":"20170512T181610", "datetime_start":"20170512T090000", "datetime_end":"20170512T160000", "has_end_time":1, "date_start":"2017-05-12", "date_end":"2017-05-12", "time_start":"09:00:00", "time_end":"16:00:00", "time_zone":"America\/Detroit", "event_title":"Chemistry-Biology Interface Symposium", "occurrence_title":"", "combined_title":"Chemistry-Biology Interface Symposium: Mark Von Zastrow (University of California, San Francisco)", "event_subtitle":"Mark Von Zastrow (University of California, San Francisco)", "event_type":"Other", "event_type_id":"22", "description":"G protein-coupled receptors (GPCRs) comprise nature's largest family of signaling receptors and regulate essentially every physiological process in animals. For many years GPCRs were thought to mediate ligand-dependent signaling only from the plasma membrane. I will discuss emerging evidence that receptors signal also from internal membranes and what we presently known about the functional significance of this 'inner life'.\nMark Von Zastrow (University of California, San Francisco)", "occurrence_notes":null, "guid":"40853-8807870@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/40853", "building_id":"1000158", "building_name":"Chemistry Dow Lab", "campus_maps_id":"34", "room":"Rackham Assembly Hall, 4th Floor\/Chemistry Atrium", "location_name":"Chemistry Dow Lab", "has_livestream":0, "cost":"", "tags":["Science","Chemistry"], "website":"", "sponsors":[ { "group_name":"Department of Chemistry", "group_id":"3761", "website":"https:\/\/lsa.umich.edu\/chem" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":8807870 } , "40187-8516441": { "datetime_modified":"20170510T144424", "datetime_start":"20170512T090000", "datetime_end":"20170512T170000", "has_end_time":1, "date_start":"2017-05-12", "date_end":"2017-05-12", "time_start":"09:00:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"Cosmogonic Tattoos", "occurrence_title":"", "combined_title":"Cosmogonic Tattoos: Jim Cogswell", "event_subtitle":"Jim Cogswell", "event_type":"Exhibition", "event_type_id":"7", "description":"In celebration of the University\u2019s Bicentennial in 2017, artist and professor Jim Cogswell has been invited by the Kelsey Museum of Archaeology and the University of Michigan Museum of Art to create a set of public window installations in response to the objects in their collections. Titled Cosmogonic Tattoos, his project will use adhesive vinyl images applied in saturated colors to windows in the two buildings, highlighting the role of these museums in the life of our campus community. Through close examination of objects separated from us by deep chronological and cultural divides, imaginatively transformed within our campus context, this project celebrates the power of architecture, ornament, and material objects to shape knowledge, historical memory, and cultural identity. \r\n\r\nLook for displays in the UMMA from April 22-Dec. 3, the exterior of the Kelsey Museum from June 2-Dec. 17, and in the interior special exhibition space of the Kelsey Museum from June 2-Sept. 10.\r\n\r\nFor information on-the-go about this event and all other Bicentennial happenings, download our free mobile app: http:\/\/guidebook.com\/g\/umich200.", "occurrence_notes":null, "guid":"40187-8516441@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/40187", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Kelsey Museum of Archaeology, UMMA", "has_livestream":0, "cost":"", "tags":["Architecture","History","Exhibition","Culture","Bicentennial","Art","Museum","Interdisciplinary","UMMA","umich200"], "website":"http:\/\/umma.umich.edu\/exhibitions\/2017\/cosmogonic-tattoos", "sponsors":[ { "group_name":"Bicentennial Office", "group_id":"3612", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2017\/04\/event_40187_original.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2017\/04\/event_40187_original.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2017\/04\/event_40187_original.jpeg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2017\/04\/event_40187_original.jpeg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2017\/04\/event_40187_original.jpeg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2017\/04\/event_40187_original.jpeg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2017\/04\/event_40187_original.jpeg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2017\/04\/event_40187_original.jpeg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2017\/04\/event_40187_original.jpeg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2017\/04\/event_40187_original.jpeg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2017\/04\/event_40187_original.jpeg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2017\/04\/event_40187_original.jpeg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2017\/04\/event_40187_original.jpeg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2017\/04\/event_40187_original.jpeg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2017\/04\/event_40187_original.jpeg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2017\/04\/event_40187_original.jpeg" }, "occurrence_count":181, "first_occurrence":8516421 } , "40491-8578220": { "datetime_modified":"20170411T130447", "datetime_start":"20170512T090000", "datetime_end":"20170512T100000", "has_end_time":1, "date_start":"2017-05-12", "date_end":"2017-05-12", "time_start":"09:00:00", "time_end":"10:00:00", "time_zone":"America\/Detroit", "event_title":"Drug Discovery Seminar - \"Chemotherapy for the 21st Century: Non-ototoxic Designer Aminoglycosides\"", "occurrence_title":"", "combined_title":"Drug Discovery Seminar - \"Chemotherapy for the 21st Century: Non-ototoxic Designer Aminoglycosides\": Jochen Schacht, Ph.D.", "event_subtitle":"Jochen Schacht, Ph.D.", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"Ototoxicity is thought to be inherent to aminoglycosides, compromising the clinical use of these important antibacterials. While we have shown clinically successful pharmacological mitigation of aminoglycoside-induced hearing loss (New Engl. J. Med. 354:1856-1857, 2006), chemotherapy of the future would benefit from aminoglycosides effective against multi-drug resistant bacteria but with no or little ototoxic potential. \r\n\r\nWe have entered collaborations with the laboratories of Dr. Erik B\u00f6ttger (Z\u00fcrich) and Dr. Timor Baasov (Haifa) in order to develop non-ototoxic designer aminoglycosides as antibacterials and as stop-codon suppressors. Potential ototoxicity is determined during the design phase of new drugs by a screen with explants from the inner ear of CBA mice and in guinea pigs in vivo. Our mechanistic concept postulates a key role for the mitochondrial ribosome in aminoglycoside ototoxicity (Hear. Res. 303:12-19, 2013). We have earlier reported (PNAS 109:10984-10989, 2012) that apramycin, a structurally unique aminoglycoside in veterinary oral use for treatment of intestinal infections, shows low activity towards eukaryotic ribosomes, including hybrid ribosomes carrying the aminoglycoside-susceptibility A1555G allele. This finding led to the proof-of-concept that antibacterial activity can be dissected from aminoglycoside ototoxicity, and we have now developed aminoglycoside compounds with low ototoxic potential. New lead compounds promise a safety margin (antibacterial efficacy vs. ototoxicity) more than an order of magnitude better than gentamicin.", "occurrence_notes":null, "guid":"40491-8578220@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/40491", "building_id":"1005047", "building_name":"Palmer Commons", "campus_maps_id":"188", "room":"Forum Hall", "location_name":"Palmer Commons", "has_livestream":0, "cost":"", "tags":["Science","Medicine"], "website":"", "sponsors":[ { "group_name":"Center for the Discovery of New Medicines - CDNM", "group_id":"3371", "website":"http:\/\/cdnm.lsi.umich.edu" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":8578220 } , "40171-8508873": { "datetime_modified":"20170403T121709", "datetime_start":"20170512T090000", "datetime_end":"20170512T170000", "has_end_time":1, "date_start":"2017-05-12", "date_end":"2017-05-12", "time_start":"09:00:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"Exhibition-on-View, \"Persistent Pasts: The Bicentennial Campus as Archive\"", "occurrence_title":"", "combined_title":"Exhibition-on-View, \"Persistent Pasts: The Bicentennial Campus as Archive\"", "event_subtitle":"", "event_type":"Exhibition", "event_type_id":"7", "description":"Combining historical research and analysis from the students in Sarah Rovang\u2019s \u201cThe Curated Campus\u201d graduate seminar and the design output of Steven Mankouche\u2019s \u201cWhat If\u201d Options Studio, Persistent Pasts reflects on the University of Michigan\u2019s campus as a repository of memory. As UM celebrates its Bicentennial year, this exhibition asks how past traditions, tensions, and technologies have left material or cultural traces on campus space today. By laying bare rarely examined aspects of the historical university alongside radical designs for an unrealized present, Persistent Pasts asks us to question entrenched conceptions of what UM should and could be, architecturally and institutionally. This exhibition is supported in part by a Bicentennial Activity Grant, co-authored by Claire Zimmerman and Sarah Rovang. \r\n\r\nThis exhibition will be on view in the Taubman College Gallery through May 19. The college gallery is open Monday - Friday, 9am - 5pm. \r\n\r\nThere will be an presentation and panel on Friday, April 7 at 6:00pm in the Art & Architecture Auditorium, followed by a reception in the college gallery.", "occurrence_notes":"Open Weekdays 9am - 5pm", "guid":"40171-8508873@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/40171", "building_id":"1000432", "building_name":"Art and Architecture Building", "campus_maps_id":"16", "room":"Taubman College Gallery (Room 2106)", "location_name":"Art and Architecture Building", "has_livestream":0, "cost":"", "tags":["History","Bicentennial","Architecture"], "website":"", "sponsors":[ { "group_name":"A. 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The two-day conference will feature traditional paper presentations, workshop sessions for dissertation chapters and articles, as well as professionalization workshops. We will deepen our interdisciplinary discussion by hosting prominent Korean studies scholars as Faculty Mentors to promote collaboration and discussion. This year, we are pleased to welcome:\r\n\r\nProfessor Charles Kim\r\n(Department of History, University of Wisconsin-Madison)\r\n\r\nProfessor Pil-Ho Kim\r\n(Department of East Asian Languages and Literatures, Ohio State University)", "occurrence_notes":null, "guid":"40635-8658491@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/40635", "building_id":"1000191", "building_name":"Michigan League", "campus_maps_id":"108", "room":"Koessler Room", "location_name":"Michigan League", "has_livestream":0, "cost":"", "tags":["Asia"], "website":"http:\/\/ii.umich.edu\/ncks\/news-events\/events\/conferences---symposia\/2017-nekst.html", "sponsors":[ { "group_name":"Nam Center for Korean Studies", "group_id":"2738", "website":"http:\/\/www.ii.umich.edu\/ncks" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2017\/05\/event_40635_original.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_thumb\/media\/attachments\/2017\/05\/event_40635_original.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2017\/05\/event_40635_original.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2017\/05\/event_40635_original.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2017\/05\/event_40635_original.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2017\/05\/event_40635_original.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2017\/05\/event_40635_original.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2017\/05\/event_40635_original.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large_lightbox\/media\/attachments\/2017\/05\/event_40635_original.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2017\/05\/event_40635_original.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2017\/05\/event_40635_original.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2017\/05\/event_40635_original.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2017\/05\/event_40635_original.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2017\/05\/event_40635_original.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_large\/media\/attachments\/2017\/05\/event_40635_original.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_thumb\/media\/attachments\/2017\/05\/event_40635_original.png" }, "occurrence_count":2, "first_occurrence":8658491 } , "33113-4691110": { "datetime_modified":"20170320T082616", "datetime_start":"20170512T100000", "datetime_end":"20170512T160000", "has_end_time":1, "date_start":"2017-05-12", "date_end":"2017-05-12", "time_start":"10:00:00", "time_end":"16:00:00", "time_zone":"America\/Detroit", "event_title":"Award Winners Exhibit", "occurrence_title":"", "combined_title":"Award Winners Exhibit", "event_subtitle":"", "event_type":"Exhibition", "event_type_id":"7", "description":"The Award Winning pieces from the 22nd Annual Exhibition of Art by Michigan Prisoners will be exhibited at the University of Michigan Detroit Center Gallery from Friday, May 5, 2017 to Saturday, May 27, 2017. 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