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        "date_end":"2016-07-19",
        "time_start":"14:00:00",
        "time_end":"16:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Dissertation Defense: Condensin and Chromatin Mediated X Chromosome Architecture in Caenorhabditis elegans",
        "occurrence_title":"",
        "combined_title":"Dissertation Defense: Condensin and Chromatin Mediated X Chromosome Architecture in Caenorhabditis elegans: Alyssa Lau",
        "event_subtitle":"Alyssa Lau",
        "event_type":"Other",
        "event_type_id":"22",
        "description":"Dosage compensation is an essential gene regulatory mechanism that balances X-linked gene expression and X to autosomal expression in organisms that utilize a chromosome-based method of sex determination. In the worm Caenorhabditis elegans dosage compensation is believed to involve two mechanisms. First, upregulation of the X chromosomes occurs in males and hermaphrodites. The mechanism of X upregulation is not known but is believed to balance X-linked gene expression levels to autosomes in males but causes X hyperactivation in hermaphrodites. This necessitates the second mechanism mediated by the activity of the dosage compensation complex (DCC), which downregulates both hermaphrodite X chromosomes by two-fold. The DCC contains a condensin-like complex, condensin IDC, similar to mitotic condensin, suggesting that it may compact the X chromosomes. The goal of my thesis is to address the long-standing hypothesis that DCC activity results in changes in X chromosome structure and explore the highly debated mechanism of X upregulation. In this research, I have uncovered that MYS-1 mediated H4K16ac decondenses the male X chromosome and contributes to upregulation of gene expression on the chromosome. This novel work supports the X upregulation hypothesis. I have also showed that condensin IDC, and the histone modifications regulated by the DCC, mediate interphase X chromosome compaction, providing the first evidence linking condensin-mediated chromosome compaction to chromosome-wide repression of gene expression. My work provided evidence that changes in higher order organization of the X chromosome plays a role both in X upregulation and condensin IDC mediated repression.",
        "occurrence_notes":null,
                "guid":"31110-4074746@events.umich.edu",
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        "building_name":"Rackham Graduate School (Horace H.)",
        "campus_maps_id":"71",
        "room":"East Conference Room, 4th Floor",
        "location_name":"Rackham Graduate School (Horace H.)",
        "has_livestream":0,
        "cost":"",
        "tags":["Biology","Research","Science"],
        "website":"",
        "sponsors":[
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                "group_name":"Department of Molecular, Cellular, and Developmental Biology",
                "group_id":"3755",
                "website":""                }                    ],
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        "datetime_end":"20160719T140000",
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        "date_start":"2016-07-19",
        "date_end":"2016-07-19",
        "time_start":"14:00:00",
        "time_end":"14:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"First Ascent Trip: Sleeping Bear Dunes and Mackinac Island",
        "occurrence_title":"",
        "combined_title":"First Ascent Trip: Sleeping Bear Dunes and Mackinac Island",
        "event_subtitle":"",
        "event_type":"Recreational \/ Games",
        "event_type_id":"18",
        "description":"Trip Duration: Tuesday, July 19, 2016 - 2:00pm to Saturday, July 23, 2016 - 4:00pm\r\n\r\nCome hike the Sleeping Bear Dunes National Lakeshore, one of the most beautiful places Michigan has to offer! This will truly be a trip to remember in places that beg to be returned to again and again. See trip details: https:\/\/recsports.umich.edu\/content\/first-ascent-july-19-23-2016-sleeping-bear-dunes\r\n\r\nFirst Ascent Trips are designed specifically for incoming UM freshmen. Learn more about the First Ascent Program: https:\/\/recsports.umich.edu\/article\/first-ascent-program",
        "occurrence_notes":"Trip Dates: Tuesday, July 19, 2016 - 2:00pm to Saturday, July 23, 2016 - 4:00pm; Registration Deadline: Monday, July 5, 2016",
                "guid":"30622-3627782@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/30622",
        "building_id":"1000728",
        "building_name":"Elbel Field Locker Building",
        "campus_maps_id":"552",
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        "location_name":"Elbel Field Locker Building",
        "has_livestream":0,
        "cost":"$450 by July 5, 2016",
        "tags":["Environment","Health & Wellness","Leadership","Outdoors","Rec Sports","Social"],
        "website":"https:\/\/recsports.umich.edu\/content\/first-ascent-july-19-23-2016-sleeping-bear-dunes",
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        "date_end":"2016-07-19",
        "time_start":"14:00:00",
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        "time_zone":"America\/Detroit",
        "event_title":"First Ascent: Sleeping Bear Dunes and Mackinac Island",
        "occurrence_title":"",
        "combined_title":"First Ascent: Sleeping Bear Dunes and Mackinac Island",
        "event_subtitle":"",
        "event_type":"Recreational \/ Games",
        "event_type_id":"18",
        "description":"First Ascent Trips are designed just for incoming UM freshmen!\r\n\r\nCome hike the Sleeping Bear Dunes National Lakeshore, one of the most beautiful places Michigan has to offer! The park was established for its outstanding natural features, including dunes, beaches, forests, and ancient glacial phenomena on the shores of Lake Michigan. We'll spend the first night camping right inside the park before hitting the trail in the morning. We'll cover around 8 miles of trail and set up camp, spending the evening exploring the dunes, taking in the sights, cooking a spectacular dinner, and hanging out around a roaring fire. After hiking out to the vans, we'll head to the solitude of Wilderness State Park on the shore of a Great Lake and spend the following day on the historic grounds of Mackinac Island. We'll explore the beautiful island by bike, the preferred method of transportation on car-free Mackinac. This will truly be a trip to remember in places that beg to be returned to again and again.",
        "occurrence_notes":null,
                "guid":"31004-3996656@events.umich.edu",
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        "location_name":"Sleeping Bear Dunes",
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        "tags":["Fitness","Health & Wellness","Outdoors","Rec Sports","Welcome to Michigan"],
        "website":"https:\/\/recsports.umich.edu\/content\/first-ascent-july-19-23-2016-sleeping-bear-dunes",
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        "date_end":"2016-07-19",
        "time_start":"14:00:00",
        "time_end":"16:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Google Visit: Campus Connections Day 1",
        "occurrence_title":"",
        "combined_title":"Google Visit: Campus Connections Day 1",
        "event_subtitle":"",
        "event_type":"Careers \/ Jobs",
        "event_type_id":"2",
        "description":"Closed session to students enrolled in the Summer Bridge Scholars Program",
        "occurrence_notes":null,
                "guid":"31449-4271766@events.umich.edu",
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        "location_name":"The Career Center office The Career Center, 3200 Student Activities Building 515 E Jefferson St, Ann Arbor, MI, United States",
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                "group_id":"1140",
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        "datetime_modified":"20160503T154655",
        "datetime_start":"20160719T180000",
        "datetime_end":"20160719T193000",
        "has_end_time":1,
        "date_start":"2016-07-19",
        "date_end":"2016-07-19",
        "time_start":"18:00:00",
        "time_end":"19:30:00",
        "time_zone":"America\/Detroit",
        "event_title":"Feelings through Fiction Therapy Group (dates & times flexible)",
        "occurrence_title":"",
        "combined_title":"Feelings through Fiction Therapy Group (dates & times flexible): The University Center for the Child and Family",
        "event_subtitle":"The University Center for the Child and Family",
        "event_type":"Lecture \/ Discussion",
        "event_type_id":"13",
        "description":"The Summer 2016 group will include:\r\n\r\n1.5 hour sessions with snacks.\r\n\r\n8 weeks of sessions.\r\n\r\n9-13 year-old (girl and boy) participants.\r\n\r\nCost flexibility based on insurance benefits (self-pay is $40\/session).\r\n\r\nScheduling flexibility since the day and time of the group sessions are determined by interest and the participant\u2019s schedule.\r\n\r\nThroughout elementary, middle, and junior high school, social interactions can become increasingly complicated and difficult to manage. Learning to navigate relationships with friends, classmates, and family can be even more challenging as girls and boys also begin to explore their identity. The Feelings through Fiction Summer 2016 Group uses a book club format to create a safe space for participants to discuss ideas and feelings common to kids their age. By the end of the eight week group, participants should be better in tune with their feelings and how to manage them, how to understand others and work through conflict, and better able to deal with challenging social situations.\r\nRegistration is required. Call (734) 764-9466 or visit uccf.umich.edu to learn more",
        "occurrence_notes":"The day and time of the group sessions are determined by interest and the participant\u2019s schedule.",
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        "tags":["Library","Discussion","Children","Books"],
        "website":"http:\/\/mari.umich.edu\/news-events\/news\/734\/feelings-through-fiction-therapy-group-summer-2016",
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        "date_end":"2016-07-20",
        "time_start":"00:00:00",
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        "event_title":"LENS Multimedia Program",
        "occurrence_title":"",
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        "event_subtitle":"",
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        "event_type_id":"22",
        "description":"Over the course of the one week summer program students are immersed in the\u00a0world of\u00a0film making from day 1 and are taught and mentored by film makers. Students will learn film vocabulary, basic filming techniques, \u00a0create a short film, story boarding\u00a0and\u00a0writing and directing films.\u00a0Please click link below for registration form.http:\/\/www.educateandreflect-k12.com\/#!registration\/n9wdq",
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        "time_start":"00:00:00",
        "time_end":"23:59:59",
        "time_zone":"America\/Detroit",
        "event_title":"The Campus Experience",
        "occurrence_title":"",
        "combined_title":"The Campus Experience",
        "event_subtitle":"",
        "event_type":"Other",
        "event_type_id":"22",
        "description":"This summer The RISE Program is\u00a0offering a program that allows students grades 6-11 the opportunity to\u00a0enjoy the campus experience. Students will participate in a 3-day workshop that gives them a look into their future(college and career). Students will spend time on the University of Ann\u00a0Arbor campus during the program. The workshop focuses on the cultivation and\ngrowth of students and guiding them towards the right path. Each session will include some aspect of career & college readiness, and character development. The workshop will consist of open dialogue, guest speakers that will share their experience and offer guidance to students, team building exercises, sit in an actual lecture and a campus tour. If there are any students that would\u00a0benefit from this program please pass the information along to them. Attached is the registration form, if there are any questions do feel free to contact us.\u00a0",
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        "date_end":"2016-07-20",
        "time_start":"08:00:00",
        "time_end":"17:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Exhibit: The Many Faces and Figures of the Four Sons in the Passover Haggadah",
        "occurrence_title":"",
        "combined_title":"Exhibit: The Many Faces and Figures of the Four Sons in the Passover Haggadah",
        "event_subtitle":"",
        "event_type":"Exhibition",
        "event_type_id":"7",
        "description":"The Four Sons of the Passover Haggadah can now be viewed in their many versions at a unique exhibit at the Jean & Samuel Frankel Center for Judaic Studies. The exhibit, featuring 29 Haggadahs from the Irwin M. Alterman Haggadah Collection, will be on display through July.  It includes Haggadahs of various shapes and sizes, ancient and modern, and in a number of different languages.\r\n\r\nThe Alterman collection was acquired by the University of Michigan Library last year with the help of the Frankel Center, and is housed in the Special Collections Library of the Harlan Hatcher Graduate Library. It includes more than 1,800 Haggadahs and is believed to be one of the largest Haggadah collections in the world. The unique compilation belonged to the late Irwin Alterman of West Bloomfield, and was donated by his widow, Marilyn McCall Alterman. \r\n\r\nPhoto courtesy of Luna Archey",
        "occurrence_notes":null,
                "guid":"30296-3402337@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/30296",
        "building_id":"1005179",
        "building_name":"202 S. Thayer",
        "campus_maps_id":"524",
        "room":"Room 2000",
        "location_name":"202 S. Thayer",
        "has_livestream":0,
        "cost":"",
        "tags":["Jewish Studies","Exhibition"],
        "website":"",
        "sponsors":[
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                "group_name":"Judaic Studies",
                "group_id":"1059",
                "website":""                }                    ],
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    {
        "datetime_modified":"20160513T150824",
        "datetime_start":"20160720T080000",
        "datetime_end":"20160720T200000",
        "has_end_time":1,
        "date_start":"2016-07-20",
        "date_end":"2016-07-20",
        "time_start":"08:00:00",
        "time_end":"20:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Gifts of Art presents Abstraction: A Graphic Study",
        "occurrence_title":"",
        "combined_title":"Gifts of Art presents Abstraction: A Graphic Study: Natasha Kohli",
        "event_subtitle":"Natasha Kohli",
        "event_type":"Exhibition",
        "event_type_id":"7",
        "description":"Chicago-based artist Natasha Kohli uses abstract acrylic paintings to convey her messages of positivity and love by pouring that energy into each piece. As a self-taught artist, Kohli is not bound to school taught rules but rather follows instinct and spontaneity. This also allows her to freely create her own processes. Moments of introspection and feelings of acceptance are what Kohli wishes to offer viewers of her work, and these goals are inspired by her deep love of spirituality and Bikram yoga.",
        "occurrence_notes":null,
                "guid":"30719-3703684@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/30719",
        "building_id":"1000316",
        "building_name":"University Hospitals",
        "campus_maps_id":"158",
        "room":"Gifts of Art Gallery \u2014 University Hospital Main Lobby, Floor 1",
        "location_name":"University Hospitals",
        "has_livestream":0,
        "cost":"",
        "tags":["Art","Health & Wellness"],
        "website":"https:\/\/www.facebook.com\/UMHSGiftsofArt",
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                "group_id":"3108",
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    {
        "datetime_modified":"20160513T151140",
        "datetime_start":"20160720T080000",
        "datetime_end":"20160720T200000",
        "has_end_time":1,
        "date_start":"2016-07-20",
        "date_end":"2016-07-20",
        "time_start":"08:00:00",
        "time_end":"20:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Gifts of Art presents Concrete Ephemera: Street Art Captured",
        "occurrence_title":"",
        "combined_title":"Gifts of Art presents Concrete Ephemera: Street Art Captured: David Zinn",
        "event_subtitle":"David Zinn",
        "event_type":"Exhibition",
        "event_type_id":"7",
        "description":"David Zinn has been drawing on sidewalks for well over a decade, using chalk and charcoal to create anamorphic 3D creatures which, when viewed at a precise angle, appear to exist in the real world. They often incorporate parts of the landscape and found objects, such as cracks in concrete or leaves on the ground. He is inspired by a desire to place cheerful art underfoot in unexpected places and to embrace the temporary nature of all things. For this exhibit, photographs of his street art installations will be on display. Zinn is a lifelong Michigander with a degree in creative writing from the U-M Residential College, and he worked for many years as a children\u2019s radio host on WCBN and Michigan Radio. Zinn will also give an artist demonstration alongside a musical performance by Magdalen Fossum in the University Hospital Courtyard on Thurs, July 21, 2016 from 12:00-1:00 pm.",
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                "guid":"30720-3703768@events.umich.edu",
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        "building_id":"1000316",
        "building_name":"University Hospitals",
        "campus_maps_id":"158",
        "room":"Gifts of Art Gallery \u2014 University Hospital Main Corridor, Floor 2",
        "location_name":"University Hospitals",
        "has_livestream":0,
        "cost":"",
        "tags":["Health & Wellness","Art"],
        "website":"https:\/\/www.facebook.com\/UMHSGiftsofArt",
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                "group_id":"3108",
                "website":"http:\/\/www.med.umich.edu\/goa\/"                }                    ],
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    {
        "datetime_modified":"20160513T143042",
        "datetime_start":"20160720T080000",
        "datetime_end":"20160720T200000",
        "has_end_time":1,
        "date_start":"2016-07-20",
        "date_end":"2016-07-20",
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        "event_title":"Gifts of Art presents Detroit Area Artists Photo Portrait Project",
        "occurrence_title":"",
        "combined_title":"Gifts of Art presents Detroit Area Artists Photo Portrait Project: Donita Simpson",
        "event_subtitle":"Donita Simpson",
        "event_type":"Exhibition",
        "event_type_id":"7",
        "description":"Donita Simpson is a Detroit based photographer who creates images of Detroit area artists in their personal creative environments. She has an M.F.A. in photography from Wayne State University, and her work is currently on exhibit in The Outwin 2016: American Portraiture Today at the Smithsonian National Portrait Gallery. The Detroit Area Artists Portrait Project contains images of artists that have been making art in and around the city for over 20 years. They are captured in an environment that inspires them, often their home or their studio.",
        "occurrence_notes":null,
                "guid":"30717-3703516@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/30717",
        "building_id":"1000317",
        "building_name":"Taubman Center",
        "campus_maps_id":"5",
        "room":"Gifts of Art Gallery \u2014 Taubman Health Center South Lobby, Floor 1",
        "location_name":"Taubman Center",
        "has_livestream":0,
        "cost":"",
        "tags":["Health & Wellness","Art"],
        "website":"http:\/\/www.med.umich.edu\/goa\/exhibits.htm",
        "sponsors":[
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                "group_id":"3108",
                "website":"http:\/\/www.med.umich.edu\/goa\/"                }                    ],
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    {
        "datetime_modified":"20160513T144136",
        "datetime_start":"20160720T080000",
        "datetime_end":"20160720T200000",
        "has_end_time":1,
        "date_start":"2016-07-20",
        "date_end":"2016-07-20",
        "time_start":"08:00:00",
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        "time_zone":"America\/Detroit",
        "event_title":"Gifts of Art presents Dimensions: Group Show",
        "occurrence_title":"",
        "combined_title":"Gifts of Art presents Dimensions: Group Show: Book Arts & Mixed Media Collective",
        "event_subtitle":"Book Arts & Mixed Media Collective",
        "event_type":"Exhibition",
        "event_type_id":"7",
        "description":"This group exhibit features a collection of contemporary artist\u2019s books. Many different styles of alternative bindings and printing methods will be shown that often push the boundaries of traditional books and, in the process, become art objects. The show will also include mixed media sculptural pieces by Ray Wetzel and Phillip Dewey. The Michigan and Ohio book artists include Char Bacon, Ruth Bardenstein, Elizabeth Begue, Barbara Brown, Cecilia Escobar, Alvey Jones and Norma Penchansky-Glasser.",
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                "guid":"30718-3703600@events.umich.edu",
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        "building_id":"1000317",
        "building_name":"Taubman Center",
        "campus_maps_id":"5",
        "room":"Gifts of Art Gallery \u2014 Taubman Health Center South Lobby, Floor 1",
        "location_name":"Taubman Center",
        "has_livestream":0,
        "cost":"",
        "tags":["Health & Wellness","Art"],
        "website":"https:\/\/www.facebook.com\/UMHSGiftsofArt",
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                "group_id":"3108",
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    {
        "datetime_modified":"20160513T142303",
        "datetime_start":"20160720T080000",
        "datetime_end":"20160720T200000",
        "has_end_time":1,
        "date_start":"2016-07-20",
        "date_end":"2016-07-20",
        "time_start":"08:00:00",
        "time_end":"20:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Gifts of Art presents Landscapes Imagined: Oil on Canvas",
        "occurrence_title":"",
        "combined_title":"Gifts of Art presents Landscapes Imagined: Oil on Canvas: Victoria Veedell",
        "event_subtitle":"Victoria Veedell",
        "event_type":"Exhibition",
        "event_type_id":"7",
        "description":"Victoria Veedell creates atmospheric landscape paintings in oil on canvas, capturing the fleeting moments of light in nature. The root of her work is an emotional reaction to the environment, implying landscapes not necessarily seen but felt. Veedell lives and works in San Francisco, and she is inspired by her global travels to places as far away as India and as near as Napa Valley, California. Travel is an important component of her work as it allows her to observe and compare gradients of color, light and atmosphere in different geographic locations.",
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                "guid":"30715-3703348@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/30715",
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        "building_name":"Taubman Center",
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        "room":"Gifts of Art Gallery \u2014 Taubman Health Center North Lobby, Floor 1",
        "location_name":"Taubman Center",
        "has_livestream":0,
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        "tags":["Art","Health & Wellness"],
        "website":"https:\/\/twitter.com\/carriemcclin",
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