{ "44342-9908987": { "datetime_modified":"20171122T141935", "datetime_start":"20171003T160000", "datetime_end":"20171003T170000", "has_end_time":1, "date_start":"2017-10-03", "date_end":"2017-10-03", "time_start":"16:00:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"Cross Campus Transfer to LSA Information Sessions", "occurrence_title":"", "combined_title":"Cross Campus Transfer to LSA Information Sessions", "event_subtitle":"", "event_type":"Presentation", "event_type_id":"16", "description":"Are you thinking about transferring to LSA from another University of Michigan school or college? Before meeting with an advisor to complete the transfer application and to discuss your individual situation, you will need to attend a group session to learn about the transfer process, LSA requirements, and LSA advising. This required information session will also help you understand how a degree in the liberal arts or sciences can help you achieve your goals.", "occurrence_notes":null, "guid":"44342-9908987@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/44342", "building_id":"1", "building_name":"Angell Hall", "campus_maps_id":"12", "room":"G243 (Newnan Advising Conference Room)", "location_name":"Angell Hall", "has_livestream":0, "cost":"", "tags":["Undergraduate Students"], "website":"", "sponsors":[ { "group_name":"Newnan LSA Academic Advising Center", "group_id":"3721", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2017\/09\/event_44342_original.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2017\/09\/event_44342_original.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2017\/09\/event_44342_original.jpeg", 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"event_title":"Margaret Cheung: Molecular Underpinning of Postsynaptic Calmodulin-dependent Calcium Signaling", "occurrence_title":"", "combined_title":"Margaret Cheung: Molecular Underpinning of Postsynaptic Calmodulin-dependent Calcium Signaling: MICDE Seminar Series", "event_subtitle":"MICDE Seminar Series", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Calcium (Ca2+) is exquisitely utilized by a cell for transducing external stimuli through its gradient of extracellular (~1000 \u03bcM) and intracellular (~0.1 \u03bcM) concentration. A broad spectrum of Ca2+ signals are encoded by protein calmodulin (CaM) through specific binding with various targets regulating CaM-dependent Ca2+ signaling pathways in neurons. I will focus on binding between CaM and two specific targets, Ca2+\/CaM-dependent protein kinase II (CaMKII) and neurogranin (Ng), as they antagonistically regulate CaM-dependent Ca2+ signaling pathways in neurons. I will show the impact of bound calmodulin (CaM)-target compound structure on the affinity of calcium (Ca2+) by integrating coarse-grained models and all-atomistic simulations with non-equilibrium physics. We discovered the molecular underpinnings of lowered affinity of Ca2+ for CaM in the presence of Ng by showing that the N-terminal acidic region of Ng peptide pries open the \u03b2-sheet structure between the Ca2+ binding loops particularly at C-domain of CaM, enabling Ca2+ release. In contrast, CaMKII peptide increases Ca2+ affinity for the C-domain of CaM by stabilizing the two Ca2+ binding loops. Through distinctive structural differences in the bound complexes of apoCaM-Ng13-49 and holoCaM-CaMKII, CaM\u2019s affinity for Ca2+ is delineated by its progressive mechanism of target binding. I will discuss them in the context of evolution and in the crowded environment.\r\n\r\nBio: Margaret Cheung is an Associate Professor of Physics at the University of Houston. 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Presented in memory of Professor Robert Glasgow.\n\nFor more information on the Organ Conference, please visit http:\/\/myumi.ch\/L1YXn \n\nPROGRAM: \nVierne- Cello Sonata, Op.27; String Quartet, Op. 12", "occurrence_notes":null, "guid":"41636-9417547@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/41636", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"First United Methodist Church of Ann Arbor, 120 S. 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Learn from leading positive organizational scholars and connect with our community of academics, students, staff, and leaders.\r\n\r\nAbout Glomb's talk:\r\nMany of us have focused on getting a good job. But how many of us have focused on making a job good? So often at work, we bumble through our days in unintentional ways. What could happen if we were more intentional and recognized the power we have to improve our work lives? \r\n\r\nUniversity of Minnesota Professor Theresa Glomb is trying to help others create positive experiences at work through growth, happiness, and satisfaction. Ultimately, Theresa\u2019s trying to make work great (or at least a little better). In this unique blend of research, personal stories, and practical disciplines, based on her TEDx talk, she shares with us simple, evidence based micro-interventions to improve our working lives.\r\n\r\nAbout Glomb:\r\nTheresa M. Glomb is the Toro Company-David M. Lilly Chair in the Carlson School of Management at the University of Minnesota. She received her PhD in social, organizational, and individual differences psychology from the University of Illinois and her BA in psychology from DePaul University. \r\n\r\nHer research suggests the important role of work events, mood, and micro-interventions in predicting on the job behavior and employee well-being. She has conducted field research in dozens of companies, including several Fortune 500 firms, with thousands of workers as participants. Her research uses a variety of methodologies including experience sampling, surveys, interviews, and physiological assessment. \r\n\r\nHer work has been published in top management journals such as the Academy of Management Journal and the Journal of Applied Psychology and cited in media outlets such as the Wall Street Journal, The Economist, and Huffington Post.\r\n\r\nHost: \r\nDavid Mayer, Associate Professor of Management & Organizations\r\n\r\nSponsors:\r\nThe Center for Positive Organizations thanks Sanger Leadership Center, Tauber Institute for Global Operations, Samuel Zell & Robert H. 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What's the Problem with Populism?", "occurrence_title":"", "combined_title":"Annual Distinguished Lecture on Europe. What's the Problem with Populism?: Jan-Werner M\u00fcller, professor of politics, Princeton University", "event_subtitle":"Jan-Werner M\u00fcller, professor of politics, Princeton University", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"Populism is said to be on the rise around the world. Some see it as a threat to democracy, others hope that it can bring political institutions closer to \"the people.\" The lecture critically assesses these claims and also suggests how we might rethink democracy in light of the dramatic political developments of 2016. \r\n\r\nJan-Werner M\u00fcller is a professor of politics at Princeton University, where he is also the founding director of the Project in the History of Political Thought at the Center for Human Values. His publications include \"Constitutional Patriotism\" (2007); \"Contesting Democracy: Political Ideas in Twentieth Century Europe\" (2011); \"Wo Europa endet: Ungarn, Br\u00fcssel und das Schicksal der liberalen Demokratie\" (2013); and \"What Is Populism?\" (2016), which has been translated into fifteen languages.\r\n\r\nThe lecture is presented in honor of Kathleen Canning, Sonya G. Rose Collegiate Professor of History; Chair, Department of History; and Arthur F. Thurnau Professor of History, German, & Women's Studies at the University of Michigan.", "occurrence_notes":null, "guid":"42984-9688340@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/42984", "building_id":"1000151", "building_name":"Museum of Art", "campus_maps_id":"11", "room":"Stern Auditorium", "location_name":"Museum of Art", "has_livestream":0, "cost":"", "tags":["Democracy","European","International","Politics"], "website":"", "sponsors":[ { "group_name":"Center for European Studies", "group_id":"1204", "website":"http:\/\/www.ii.umich.edu\/ces" }, { "group_name":"International Institute", "group_id":"1968", "website":"http:\/\/www.ii.umich.edu" }, { "group_name":"Center for Emerging Democracies", "group_id":"3096", "website":"http:\/\/www.ii.umich.edu\/emergingdemocracies" }, { "group_name":"Center for Russian, East European, and Eurasian Studies", "group_id":"3097", "website":"http:\/\/www.ii.umich.edu\/crees" }, { "group_name":"Weiser Center for Europe and Eurasia", "group_id":"3111", "website":"http:\/\/www.ii.umich.edu\/wcee" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2017\/08\/event_42984_original.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_thumb\/media\/attachments\/2017\/08\/event_42984_original.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2017\/08\/event_42984_original.jpeg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2017\/08\/event_42984_original.jpeg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2017\/08\/event_42984_original.jpeg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2017\/08\/event_42984_original.jpeg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2017\/08\/event_42984_original.jpeg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2017\/08\/event_42984_original.jpeg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large_lightbox\/media\/attachments\/2017\/08\/event_42984_original.jpeg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2017\/08\/event_42984_original.jpeg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2017\/08\/event_42984_original.jpeg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2017\/08\/event_42984_original.jpeg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2017\/08\/event_42984_original.jpeg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2017\/08\/event_42984_original.jpeg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_large\/media\/attachments\/2017\/08\/event_42984_original.jpeg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_thumb\/media\/attachments\/2017\/08\/event_42984_original.jpeg" }, "occurrence_count":1, "first_occurrence":9688340 } }