{ "86156-21631747": { "datetime_modified":"20211027T162607", "datetime_start":"20211208T120000", "datetime_end":"20211208T132000", "has_end_time":1, "date_start":"2021-12-08", "date_end":"2021-12-08", "time_start":"12:00:00", "time_end":"13:20:00", "time_zone":"America\/Detroit", "event_title":"WCEE Book Series. In The Midst Of Civilized Europe: The Pogroms Of 1918-1921 And The Onset Of The Holocaust", "occurrence_title":"", "combined_title":"WCEE Book Series. In The Midst Of Civilized Europe: The Pogroms Of 1918-1921 And The Onset Of The Holocaust: Jeffrey Veidlinger, Joseph Brodsky Collegiate Professor of History and Judaic Studies, University of Michigan", "event_subtitle":"Jeffrey Veidlinger, Joseph Brodsky Collegiate Professor of History and Judaic Studies, University of Michigan", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"Between 1918 and 1921, over a hundred thousand Jews were murdered in Ukraine by peasants, townsmen, and soldiers who blamed the Jews for the turmoil of the Russian Revolution. In hundreds of separate incidents, ordinary people robbed their Jewish neighbors with impunity, burned down their houses, ripped apart their Torah scrolls, sexually assaulted them, and killed them. Largely forgotten today, these pogroms\u2014ethnic riots\u2014dominated headlines and international affairs in their time. Aid workers warned that six million Jews were in danger of complete extermination. Twenty years later, these dire predictions would come true.\r\n \r\nJeffrey Veidlinger is Joseph Brodsky Collegiate Professor of History and Judaic Studies at the University of Michigan. His books, which include *The Moscow State Yiddish Theater* and *In the Shadow of the Shtetl*, have won a National Jewish Book Award, the Barnard Hewitt Award for Theatre Scholarship, two Canadian Jewish Book Awards, and the J. I. Segal Award.\r\n\r\nRegistration for this webinar is required at https:\/\/myumi.ch\/zxQPx\r\n\r\nIf there is anything we can do to make this event accessible to you, please contact us at weisercenter@umich.edu. Please be aware that advance notice is necessary as some accommodations may require more time for the university to arrange.", "occurrence_notes":"Register at https:\/\/myumi.ch\/zxQPx", "guid":"86156-21631747@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/86156", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Virtual", "has_livestream":0, "cost":"", "tags":["European","History","International","Jewish Studies","Russia","Ukraine"], "website":"http:\/\/www.ii.umich.edu\/wcee", "sponsors":[ { "group_name":"Weiser Center for Europe and Eurasia", "group_id":"3111", "website":"http:\/\/www.ii.umich.edu\/wcee" }, { "group_name":"Judaic Studies", "group_id":"1059", "website":"" }, { "group_name":"International Institute", "group_id":"1968", "website":"http:\/\/www.ii.umich.edu" }, { "group_name":"Center for Russian, East European, and Eurasian Studies", "group_id":"3097", "website":"http:\/\/www.ii.umich.edu\/crees" }, { "group_name":"Frankel Center for Judaic Studies", "group_id":"4621", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2021\/09\/event_86156_original-1.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2021\/09\/event_86156_original-1.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2021\/09\/event_86156_original-1.jpeg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2021\/09\/event_86156_original-1.jpeg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2021\/09\/event_86156_original-1.jpeg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2021\/09\/event_86156_original-1.jpeg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2021\/09\/event_86156_original-1.jpeg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2021\/09\/event_86156_original-1.jpeg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2021\/09\/event_86156_original-1.jpeg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2021\/09\/event_86156_original-1.jpeg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2021\/09\/event_86156_original-1.jpeg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2021\/09\/event_86156_original-1.jpeg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2021\/09\/event_86156_original-1.jpeg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2021\/09\/event_86156_original-1.jpeg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2021\/09\/event_86156_original-1.jpeg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2021\/09\/event_86156_original-1.jpeg" }, "occurrence_count":1, "first_occurrence":21631747 } , "85277-21626163": { "datetime_modified":"20220621T152447", "datetime_start":"20211208T121500", "datetime_end":"20211208T124500", "has_end_time":1, "date_start":"2021-12-08", "date_end":"2021-12-08", "time_start":"12:15:00", "time_end":"12:45:00", "time_zone":"America\/Detroit", "event_title":"VIRTUAL | CEW+Inspire Midweek Mindfulness-Guided Sit", "occurrence_title":"", "combined_title":"VIRTUAL | CEW+Inspire Midweek Mindfulness-Guided Sit", "event_subtitle":"", "event_type":"Well-being", "event_type_id":"12", "description":"As part of the\u00a0CEW+Inspire\u00a0initiative, CEW+ holds mindful meditation sits virtually on Wednesdays at 12:15.\r\n\r\nRSVP here to receive the Zoom link: https:\/\/myumi.ch\/r8zv7\r\n\r\nMindfulness Meditation is a skill that can be learned and when practiced has the power to enhance a sense of wellbeing, focus, and interconnectedness. As we all continue to navigate uncertainty and challenges that are inherent in the act of being human, we benefit from and are grateful for diverse cultures and traditions across the globe. Collectively they have passed on a wide variety of contemplative practices that encourage reflection, silence, and centering into the present moment to help us cope and better respond. Engaging in contemplative practices support the individual, by cultivating a sense of awareness and well-being, and benefit society by enhancing one\u2019s capacity to create connection and community, and to become an agent of positive social change. There are many forms of contemplative practices, including meditation. Mindfulness meditation is one form aimed to help focus our awareness on the present moment as it unfolds, moment to moment, without judgment. Research on mindfulness continues to find a wide range of benefits. In short, Mindfulness may be viewed as cognitive training that bolsters our ability to handle stress, poor mood, and threat. It also increases our capacity to focus our attention on what is most important to us and to be more compassionate to ourselves and to others.\r\n\r\nOn Wednesdays from 12:15 - 12:45 pm,\u00a0we come together in community to practice this skill in an open and supportive virtual space. Whether you are new to mindfulness meditation or are an experienced practitioner each session is designed to offer guidance and support to assist you. Join this supportive community and experience the gift of present moment awareness.", "occurrence_notes":null, "guid":"85277-21626163@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/85277", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Virtual", "has_livestream":0, "cost":"", "tags":["Free","Mindfulness","Virtual","Well-being","Wellness","Work-life Balance"], "website":"https:\/\/myumi.ch\/r8zv7", "sponsors":[ { "group_name":"CEW+", "group_id":"2927", "website":"http:\/\/cew.umich.edu" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2021\/12\/event_85277_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2021\/12\/event_85277_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2021\/12\/event_85277_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2021\/12\/event_85277_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2021\/12\/event_85277_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2021\/12\/event_85277_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2021\/12\/event_85277_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2021\/12\/event_85277_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2021\/12\/event_85277_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2021\/12\/event_85277_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2021\/12\/event_85277_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2021\/12\/event_85277_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2021\/12\/event_85277_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2021\/12\/event_85277_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2021\/12\/event_85277_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2021\/12\/event_85277_original-1.png" }, "occurrence_count":41, "first_occurrence":21626147 } , "89425-21663058": { "datetime_modified":"20211129T132610", "datetime_start":"20211208T130000", "datetime_end":"20211208T153000", "has_end_time":1, "date_start":"2021-12-08", "date_end":"2021-12-08", "time_start":"13:00:00", "time_end":"15:30:00", "time_zone":"America\/Detroit", "event_title":"A Gentle Introduction to Esri's StoryMaps", "occurrence_title":"", "combined_title":"A Gentle Introduction to Esri's StoryMaps: Do you have a story to tell? Looking for innovative ways to communicate research? Interested in exploring multimedia assignments?", "event_subtitle":"Do you have a story to tell? Looking for innovative ways to communicate research? Interested in exploring multimedia assignments?", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"ArcGIS StoryMaps provide a powerful and engaging approach for educational activities, instructional delivery, dissemination of research, public outreach, and more! Together we\u2019ll explore StoryMaps\u2019 intuitive interface to combine interactive maps, text, images, and multimedia content into a web-based, visually compelling, responsive narrative. We\u2019ll address accessibility, preservation, and portability of your StoryMaps, highlighting both strengths and limitations of the platform.\r\n\r\n(This will be a virtual workshop; Zoom connection info will be sent to registered participants shortly before the workshop.)", "occurrence_notes":"Register for Zoom link: https:\/\/ttc.iss.lsa.umich.edu\/ttc\/sessions\/a-gentle-introduction-to-esri-storymaps\/", "guid":"89425-21663058@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/89425", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Virtual", "has_livestream":0, "cost":"", "tags":["Digital Humanities","Digital Scholarship","Digital Studies","Gis","Humanities","Lsa","Qualitative Social Sciences"], "website":"https:\/\/ttc.iss.lsa.umich.edu\/ttc\/sessions\/a-gentle-introduction-to-esri-storymaps\/", "sponsors":[ { "group_name":"LSA Technology Services", "group_id":"4207", "website":"" }, { "group_name":"University Library", "group_id":"1186", "website":"https:\/\/www.facebook.com\/UMichLibrary\/" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2021\/11\/event_89425_original-1.jpg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2021\/11\/event_89425_original-1.jpg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2021\/11\/event_89425_original-1.jpg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2021\/11\/event_89425_original-1.jpg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2021\/11\/event_89425_original-1.jpg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2021\/11\/event_89425_original-1.jpg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2021\/11\/event_89425_original-1.jpg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2021\/11\/event_89425_original-1.jpg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large_lightbox\/media\/attachments\/2021\/11\/event_89425_original-1.jpg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2021\/11\/event_89425_original-1.jpg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2021\/11\/event_89425_original-1.jpg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2021\/11\/event_89425_original-1.jpg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid\/media\/attachments\/2021\/11\/event_89425_original-1.jpg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2021\/11\/event_89425_original-1.jpg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_large\/media\/attachments\/2021\/11\/event_89425_original-1.jpg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_thumb\/media\/attachments\/2021\/11\/event_89425_original-1.jpg" }, "occurrence_count":1, "first_occurrence":21663058 } , "89633-21664590": { "datetime_modified":"20211130T173215", "datetime_start":"20211208T130000", "datetime_end":"20211208T150000", "has_end_time":1, "date_start":"2021-12-08", "date_end":"2021-12-08", "time_start":"13:00:00", "time_end":"15:00:00", "time_zone":"America\/Detroit", "event_title":"BLI Destress Fest: Wind Down Wednesday", "occurrence_title":"", "combined_title":"BLI Destress Fest: Wind Down Wednesday", "event_subtitle":"", "event_type":"Well-being", "event_type_id":"12", "description":"It is that time of the year again! With finals coming up, the BLI is here to take off some of your stress! We are excited to invite you to our DESTRESS FEST to combat your anxiety! \r\n\r\nCome relax with the BLI:\r\n- Chair Massages \ud83d\udc86(Please note, while everyone is welcome to this event, the massages are reserved for BLI Members!)\r\n- Coloring activities \ud83c\udfa8\r\n- A HUGE jigsaw puzzle \ud83e\udde9\r\n- and Board Games \ud83c\udfb2\r\n- First 20 to register get a Zingerman's Grab and Go Lunch! All those on the waitlist are welcome to attend :)", "occurrence_notes":null, "guid":"89633-21664590@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/89633", "building_id":"1000165", "building_name":"Weiser Hall", "campus_maps_id":"47", "room":"8th floor - BLI", "location_name":"Weiser Hall", "has_livestream":0, "cost":"", "tags":["Leadership","Social","Well-being"], "website":"https:\/\/sessions.studentlife.umich.edu\/track\/event\/session\/50943", "sponsors":[ { "group_name":"Barger Leadership Institute", "group_id":"3540", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2021\/11\/event_89633_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2021\/11\/event_89633_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2021\/11\/event_89633_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2021\/11\/event_89633_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2021\/11\/event_89633_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2021\/11\/event_89633_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2021\/11\/event_89633_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2021\/11\/event_89633_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large_lightbox\/media\/attachments\/2021\/11\/event_89633_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2021\/11\/event_89633_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2021\/11\/event_89633_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2021\/11\/event_89633_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2021\/11\/event_89633_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2021\/11\/event_89633_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2021\/11\/event_89633_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2021\/11\/event_89633_original-1.png" }, "occurrence_count":1, "first_occurrence":21664590 } , "89542-21664062": { "datetime_modified":"20211129T095043", "datetime_start":"20211208T130000", "datetime_end":"20211208T140000", "has_end_time":1, "date_start":"2021-12-08", "date_end":"2021-12-08", "time_start":"13:00:00", "time_end":"14:00:00", "time_zone":"America\/Detroit", "event_title":"BME PhD Defense: Melissa Lemke", "occurrence_title":"", "combined_title":"BME PhD Defense: Melissa Lemke: A Systems Approach to Elucidate Personalized Mechanistic Complexities of Antibody-Fc Receptor Activation Post-Vaccination", "event_subtitle":"A Systems Approach to Elucidate Personalized Mechanistic Complexities of Antibody-Fc Receptor Activation Post-Vaccination", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"Department of Biomedical Engineering Final Oral Examination\r\n\r\nMelissa Lemke\r\n\r\nA Systems Approach to Elucidate Personalized Mechanistic Complexities of Antibody-Fc Receptor Activation Post-Vaccination\r\n\r\nOne of the most significant challenges to current human healthcare is the emergence of antigenically variable viruses that evade traditional vaccination approaches. Human immunodeficiency virus (HIV) is one such virus that emerged over 30 years ago and still has no effective vaccine. Like many other antigenically variable viruses, after infection, HIV quickly mutates to evade broadly neutralizing antibodies that bind tightly to key sites to prevent infection. Over 250 clinical trials have been performed to date to develop an effective HIV vaccine, with only one providing moderate protection; the RV144 Thai trial, estimated to be 31% effective but has not been replicated in other populations. Rather than broadly neutralizing antibodies, the trial identified IgG antibodies with the capacity to induce Fc effector functions as a correlate of protection. These functions are triggered by less specific antibodies that bind HIV antigen and Fc receptors on the surface of innate immune cells to form immune complexes to activate protective cellular functions. Understanding how to increase the formation of IgG-FcR complexes may improve vaccine efficacy, but variation in IgG and FcR features across individuals suggests that protective mechanisms need to be understood on a personalized basis. There are multiple subclasses of protective IgGs, each having different concentrations and affinities to FcRs in different individuals. Genetics can also play a role, with FcR polymorphisms changing FcR binding affinity and IgG1 allotypes changing IgG subclass concentrations. Mechanistic ordinary differential equation (ODE) modeling of this system offers the opportunity to account for these factors on a personalized basis and deconvolve which are most influential and determine how to improve protection universally.\r\n\r\n\r\nWe developed an ODE model of IgG-Fc\u03b3RIIIa immune complex formation to elucidate how personalized variability in IgG subclass concentration and genetic factors may contribute to complex formation after vaccination. We validated the model with RV144 plasma samples and used it to discover new mechanisms that underpin complex formation. This enabled the identification of genetic and post-translational features that influenced complex formation and suggested the best interventions on a personalized basis. For example, although IgG3 was associated with protection in RV144 and has the highest affinity to Fc\u03b3RIIIas, the model suggested that IgG1 may play a more essential role, though it also may be highly variable; due to high IgG1 concentration variability across individuals. The model identified RV144 vaccinees who were predicted to be sensitive, insensitive, or negatively affected by increases in HIV-specific IgG1, which was validated experimentally with the addition of HIV-specific IgG1 monoclonal antibodies to vaccine samples. The model also gave important insights into how to maximize IgG-Fc\u03b3RIIIa complex formation in different genetic backgrounds. We found that individuals with certain IgG1 allotypes were predicted to be more responsive to vaccine adjuvant strategies that increase antibody affinity (e.g., glycosylation modifications) compared to other allotypes, which were predicted to be more responsive to vaccine boosting regimens that increase IgG1 antibody concentration. Finally, simulations in mixed-allotype populations suggest that the benefit of boosting IgG1 concentration versus IgG1 affinity may depend upon the frequency of a specific IgG1 allotype (G1m-1,3) in the population. 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