{
    "108481-21819637":
    {
        "datetime_modified":"20230731T103959",
        "datetime_start":"20230803T130000",
        "datetime_end":"20230803T140000",
        "has_end_time":1,
        "date_start":"2023-08-03",
        "date_end":"2023-08-03",
        "time_start":"13:00:00",
        "time_end":"14:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Physics Graduate Student Symposium (PGSS) | Ultrafast Time-Resolved Spectroscopy Using Optical and X-ray Probes Elucidates the Structural and Electronic Evolution of Photoexcited Coenzyme B12",
        "occurrence_title":"",
        "combined_title":"Physics Graduate Student Symposium (PGSS) | Ultrafast Time-Resolved Spectroscopy Using Optical and X-ray Probes Elucidates the Structural and Electronic Evolution of Photoexcited Coenzyme B12: Taylor McClain, Fifth Year (U-M Biophysics)",
        "event_subtitle":"Taylor McClain, Fifth Year (U-M Biophysics)",
        "event_type":"Workshop \/ Seminar",
        "event_type_id":"21",
        "description":"Coenzyme B12, also known as adenosylcobalamin (AdoCbl), is an important enzymatic cofactor in prokaryotic and eukaryotic species. This molecule consists of a central cobalt coordinated equatorially to a corrin ring ligand, with a lower axial dimethylbenzimidazole \u03b1-ligand and an upper axial deoxyadenosyl \u03b2-ligand. AdoCbl\u2019s ground state reactivity has been studied in detail, but it was only recently that its role as chromophore in the bacterial photoreceptor protein CarH showed a biological usage of the molecule\u2019s inherent light-sensitivity. The light-induced response of AdoCbl can be characterized using time-resolved spectroscopies. Presently, our group has performed studies with transient absorption (TA) UV-Vis spectroscopy, X-ray absorption spectroscopy, and X-ray emission spectroscopy. TA spectroscopy provides electronic information about the valence orbitals of the system. The X-ray spectroscopies are element-specific probes of the electronic and atomic structure around the central cobalt atom of the AdoCbl. These studies reveal a distinct solvent-dependence of AdoCbl photochemistry as well as a dynamic dance of structural distortions immediately following light excitation. Time-dependent density functional theory (TD-DFT) and finite difference method (FDM) calculations are used to simulate the X-ray absorption and emission spectra. This information is crucial for understanding the CarH protein more deeply as well as bringing cobalamin-based light-mediated drug delivery and optogenetic applications closer to reality.",
        "occurrence_notes":null,
                "guid":"108481-21819637@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/108481",
        "building_id":"1000167",
        "building_name":"West Hall",
        "campus_maps_id":"163",
        "room":"340",
        "location_name":"West Hall",
        "has_livestream":0,
        "cost":"",
        "tags":["Graduate Students","Physics"],
        "website":"",
        "sponsors":[
             {
                "group_name":"Department of Physics",
                "group_id":"1965",
                "website":""                }                    ],
        "image_url":"",
        "styled_images":{
                                        "event_thumb":"",
                                            "event_large":"",
                                            "event_large_2x":"",
                                            "event_large_lightbox":"",
                                            "group_thumb":"",
                                            "group_thumb_square":"",
                                            "group_large":"",
                                            "group_large_lightbox":"",
                                            "event_large_crop":"",
                                            "event_list":"",
                                            "event_list_2x":"",
                                            "event_grid":"",
                                            "event_grid_2x":"",
                                            "event_feature_large":"",
                                            "event_feature_thumb":""                    },
        "occurrence_count":1,
        "first_occurrence":21819637
    }    ,    "109044-21820833":
    {
        "datetime_modified":"20230710T121027",
        "datetime_start":"20230803T130000",
        "datetime_end":"20230803T150000",
        "has_end_time":1,
        "date_start":"2023-08-03",
        "date_end":"2023-08-03",
        "time_start":"13:00:00",
        "time_end":"15:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"RISEing Scholars Spotlight",
        "occurrence_title":"",
        "combined_title":"RISEing Scholars Spotlight",
        "event_subtitle":"",
        "event_type":"Other",
        "event_type_id":"22",
        "description":"What can fossil plants reveal about the past? And what do proteins have to do with cancer? Find out at this special Scientist Spotlight featuring high school scholars from the D-RISE and Earth-RISE programs, two immersive summer research experiences for the next generation of scientists. Participate in hands-on-activities and explore a variety of topics ranging from paleobotany to medical science.",
        "occurrence_notes":null,
                "guid":"109044-21820833@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/109044",
        "building_id":"1005169",
        "building_name":"Museum of Natural History",
        "campus_maps_id":"646",
        "room":"",
        "location_name":"Museum of Natural History",
        "has_livestream":0,
        "cost":"",
        "tags":["Free","Museum","natural history museum","Natural Sciences","Science"],
        "website":"",
        "sponsors":[
             {
                "group_name":"Museum of Natural History",
                "group_id":"3445",
                "website":""                }                    ],
        "image_url":"",
        "styled_images":{
                                        "event_thumb":"",
                                            "event_large":"",
                                            "event_large_2x":"",
                                            "event_large_lightbox":"",
                                            "group_thumb":"",
                                            "group_thumb_square":"",
                                            "group_large":"",
                                            "group_large_lightbox":"",
                                            "event_large_crop":"",
                                            "event_list":"",
                                            "event_list_2x":"",
                                            "event_grid":"",
                                            "event_grid_2x":"",
                                            "event_feature_large":"",
                                            "event_feature_thumb":""                    },
        "occurrence_count":1,
        "first_occurrence":21820833
    }    }