{ "136285-21878394": { "datetime_modified":"20250722T094520", "datetime_start":"20250807T160000", "datetime_end":"20250807T170000", "has_end_time":1, "date_start":"2025-08-07", "date_end":"2025-08-07", "time_start":"16:00:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"Merck Symposium", "occurrence_title":"", "combined_title":"Merck Symposium: Ryan Shenvi from Scripps Research in California", "event_subtitle":"Ryan Shenvi from Scripps Research in California", "event_type":"Conference \/ Symposium", "event_type_id":"5", "description":"Ryan Shenvi Title: Attempts to deliver on the promise of natural products\r\n\r\nRyan Shenvi Abstract: Natural product (NP) total synthesis involves experimental discovery and decision-making at every stage: why this route and not another? Why this intermediate and not its close analog? Why this NP, optimized for the producer organism\u2019s survival in its ecological niche, and not a close analog, optimized for therapeutic use? The vast numbers of options surrounding all possible choices exceed human capacity for evaluation. Our group has begun to make these decisions with the aid of computation. These calculations, which contain numerous approximations, are not taken at face value, but instead subjected to experimental interrogation. If correct, however, computational predictions can greatly simplify our choice of reagent, choice of intermediate (subTGT), or even choice of NP target (TGT).", "occurrence_notes":null, "guid":"136285-21878394@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/136285", "building_id":"1005047", "building_name":"Palmer Commons", "campus_maps_id":"188", "room":"Forum Hall", "location_name":"Palmer Commons", "has_livestream":0, "cost":"", "tags":["Biosciences","Chemistry","Organic Chemistry","Science"], "website":"", "sponsors":[ { "group_name":"Department of Chemistry", "group_id":"3761", "website":"https:\/\/lsa.umich.edu\/chem" }, { "group_name":"Organic Chemistry", "group_id":"4389", "website":"" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21878394 } , "134783-21875114": { "datetime_modified":"20250509T114740", "datetime_start":"20250807T200000", "datetime_end":"", "has_end_time":0, "date_start":"2025-08-07", "date_end":"", "time_start":"20:00:00", "time_end":"", "time_zone":"America\/Detroit", "event_title":"Doolin'", "occurrence_title":"", "combined_title":"Doolin': Presented by The Ark", "event_subtitle":"Presented by The Ark", "event_type":"Performance", "event_type_id":"15", "description":"France\u2019s premier Celtic band\r\n\r\nAfter three years of breakout touring at some of the biggest roots festivals in the United States and Canada, and another three years locked out of the live performance world they have so ambitiously cultivated, Doolin\u2019, France\u2019s premiere practitioners of Irish and Celtic music, return to touring with a new album entitled CIRCUS BOY. \r\n\r\nRecorded in part in the US (Chicago, Kansas City and Pittsburgh) during their 2019 tour, the album was completed at the legendary Studio Ferber in Paris, France, under the direction of two legendary producers, Olivier Lude and Patrice Renson, both of whom have collaborated with some of the biggest names in French music. While their 2016 album drew its inspiration from the fusion of traditional Irish music, French chanson, and American roots music, CIRCUS BOY is resolutely more adventurous, as evidenced by their original compositions as well as by the added punch and sonic elements that were brought to the project by producers Lude and Renson. \r\n\r\nWilfried Besse\u2019s vocals are supported as usual by the driving rhythm section of Josselin Fournel (percussion), S\u00e9bastien Sauni\u00e9 (bass) and Nicolas Besse (guitars), and the trad-Irish influence remains evidenced through the whistles of Jacob Fournel, the bodhran of his brother, Josselin, and the nimble accordion playing of Nicolas\u2019 brother, Wilfried. But CIRCUS BOY represents a more powerful and bigger musical vision for the band, made possible by the introduction of piano, drums, and brass as new sonic elements. That said, the Irish music tradition is not complete without the presence of a fiddle or two, and on CIRCUS BOY Doolin\u2019 includes three of the best European fiddlers of the genre: Niahm Gallagher, Niall Murphy, and Guilhem Cavaill\u00e9, himself a founding member of the band.", "occurrence_notes":null, "guid":"134783-21875114@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/134783", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"ARK Reserved", "has_livestream":0, "cost":"See site for pricing information", "tags":["Ark","Mutotix"], "website":"https:\/\/mutotix.umich.edu\/5717\/5718", "sponsors":[ { "group_name":"Michigan Union Ticket Office (MUTO)", "group_id":"1053", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2025\/04\/event_134783_original-1.jpg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2025\/04\/event_134783_original-1.jpg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2025\/04\/event_134783_original-1.jpg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2025\/04\/event_134783_original-1.jpg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2025\/04\/event_134783_original-1.jpg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2025\/04\/event_134783_original-1.jpg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2025\/04\/event_134783_original-1.jpg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2025\/04\/event_134783_original-1.jpg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2025\/04\/event_134783_original-1.jpg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2025\/04\/event_134783_original-1.jpg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2025\/04\/event_134783_original-1.jpg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2025\/04\/event_134783_original-1.jpg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2025\/04\/event_134783_original-1.jpg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2025\/04\/event_134783_original-1.jpg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2025\/04\/event_134783_original-1.jpg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2025\/04\/event_134783_original-1.jpg" }, "occurrence_count":1, "first_occurrence":21875114 } }