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        "has_end_time":1,
        "date_start":"2026-10-20",
        "date_end":"2026-10-20",
        "time_start":"09:00:00",
        "time_end":"20:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Faster and More Fun: American Home Cooking in the 1920s",
        "occurrence_title":"",
        "combined_title":"Faster and More Fun: American Home Cooking in the 1920s: American Home Cooking",
        "event_subtitle":"American Home Cooking",
        "event_type":"Exhibition",
        "event_type_id":"7",
        "description":"Visit the Hatcher Gallery Exhibit Room to see historical materials that illustrate women\u2019s changing relationship with food, cooking, and technology during the heady decade of the 1920s, sandwiched between WWI and the Great Depression. This exhibit features materials from the Janice Bluestein Longone Culinary Archive, as well as select items from the Art, Architecture, and Engineering Special Collections and the Transportation History Collection.\n\nAs America rang in a new decade in the 1920s, cookbook authors and appliance manufacturers stood ready to offer the newly emancipated and forward-thinking American woman a vision for her future, a vision that would be scientifically  grounded, speedy enough to make time for leisure as well as housework, and guaranteed to bring fun to that most humdrum of chores: planning and preparing meals for a family three times a day, 365 days a year.",
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                "guid":"150658-21909800@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/150658",
        "building_id":"1000181",
        "building_name":"Hatcher Graduate Library",
        "campus_maps_id":"65",
        "room":"Hatcher Gallery Exhibit Room, 1st Floor",
        "location_name":"Hatcher Graduate Library",
        "has_livestream":0,
        "cost":"",
        "tags":["Culinary History","Free","Library"],
        "website":"https:\/\/www.lib.umich.edu\/events",
        "sponsors":[
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                "group_id":"1186",
                "website":"https:\/\/www.facebook.com\/UMichLibrary\/"                }                    ],
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    {
        "datetime_modified":"20260728T142037",
        "datetime_start":"20261020T090000",
        "datetime_end":"20261020T170000",
        "has_end_time":1,
        "date_start":"2026-10-20",
        "date_end":"2026-10-20",
        "time_start":"09:00:00",
        "time_end":"17:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Grand Vision",
        "occurrence_title":"",
        "combined_title":"Grand Vision: An exhibition by Olayami Dabls",
        "event_subtitle":"An exhibition by Olayami Dabls",
        "event_type":"Exhibition",
        "event_type_id":"7",
        "description":"Visiting artist Olayami Dabls is a storyteller, curator, educator, and mentor. He is the founder of the MBAD African Bead Museum in Detroit. Through material culture, Dabls presents commentary on the past, present, and future from African and African-American perspectives, with the understanding that generations of African ancestors used visual materials to convey information about their identity as well as send messages for healing and protection. Dabls is a luminary; for decades he has re-imagined what a museum space can be, accessible to everyone, free from the underpinnings of colonialism and the Western, often white, frame. *Grand Vision* includes a conceptual installation in the Gallery, presenting Dabls\u2019s own work in visual conversation with African beads and artifacts from Dabls\u2019s Bead Museum collections. \n\nAdditionally, Dabls\u2019s iconic outdoor sculpture *Iron Teaching Rocks Table Manners* will be installed on the U-M campus grounds near UMMA, at the intersection of State Street and South University from September 17- October 11, 2026. The project\u2019s range intends to more fully articulate the many facets of Dabls\u2019 creative practice, and the overlay of art, history, identity, community, and healing.",
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        "building_id":"1005179",
        "building_name":"202 S. Thayer",
        "campus_maps_id":"524",
        "room":"Institute for the Humanities Gallery",
        "location_name":"202 S. Thayer",
        "has_livestream":0,
        "cost":"",
        "tags":["African American","Art","Detroit","Exhibition","Humanities","Michigan Arts Festival","Visual Arts"],
        "website":"http:\/\/www.lsa.umich.edu\/humanities",
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                "group_id":"1130",
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    {
        "datetime_modified":"20260922T182157",
        "datetime_start":"20261020T090000",
        "datetime_end":"20261020T163000",
        "has_end_time":1,
        "date_start":"2026-10-20",
        "date_end":"2026-10-20",
        "time_start":"09:00:00",
        "time_end":"16:30:00",
        "time_zone":"America\/Detroit",
        "event_title":"Student Life Facilitation Training October 2026",
        "occurrence_title":"Student Life Facilitation Training Day 2",
        "combined_title":"Student Life Facilitation Training October 2026: Multiple conference events and sessions: Student Life Facilitation Training Day 2",
        "event_subtitle":"Multiple conference events and sessions",
        "event_type":"Conference \/ Symposium",
        "event_type_id":"5",
        "description":"The Student Life Facilitation Committee and Student Life Professional Development are proud to announce that we are offering a staff-oriented facilitation training opportunity once again! A similar training has been offered to students and we have adapted the curriculum to provide staff with the skills and knowledge necessary to build confidence and ability in facilitation.The training will take place on Monday, October 19 & Tuesday, October 20, 9:00am-4:30pm in the Connector Multipurpose Room. Attendance is required for the full training. A light breakfast & lunch will be provided.The training is comprised of a 16-hour training curriculum designed to: 1) prepare participants to facilitate dialogues, meetings, and workshops involving two or more individuals; 2) be available to staff within Student Life; 3) supplement unit-specific trainings; 4) maximize divisional resources; and 5) be module-based and repeatable.We encourage you to register, participate, and gain invaluable skills throughout the training. This training is free to Student Life staff and $100 for staff in other departments. We have a minimum cap of 10 and a maximum cap of 16 participants. If we do not meet the minimum we will need to cancel the training. If we meet the maximum you will have the opportunity to join a waitlist.\u00a0Please communicate any accessibility\/accommodation needs to the coordinating group at slfacilitation@umich.edu at least two weeks in advance of the training or as soon as possible.\u00a0Registration for this training closes on October 12th.",
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        "tags":["Sessions"],
        "website":"https:\/\/sessions.studentlife.umich.edu\/p\/track\/17451",
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        "datetime_modified":"20260922T093359",
        "datetime_start":"20261020T093000",
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        "has_end_time":1,
        "date_start":"2026-10-20",
        "date_end":"2026-10-20",
        "time_start":"09:30:00",
        "time_end":"11:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"CoderSpaces - Tuesdays",
        "occurrence_title":"",
        "combined_title":"CoderSpaces - Tuesdays: weekly data science hubs",
        "event_subtitle":"weekly data science hubs",
        "event_type":"Workshop \/ Seminar",
        "event_type_id":"21",
        "description":"Are you grappling with a piece of code, trying to compute on a cluster, or just getting started with a new method such as machine learning? Then we might have just the right space for you.\n\nAll members of the U-M community are invited to join our weekly virtual CoderSpaces to get research support and connect with others.\n\nTuesdays, 9:30-11 a.m. ET, via Zoom (Meeting ID: 513 103 7575)\nWednesdays, 1:30-3 p.m. ET, via Zoom (Meeting ID: 513 103 7575)",
        "occurrence_notes":"Please sign in with your U-M Zoom account (SSO) to access the meeting room.",
                "guid":"152608-21914058@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/152608",
        "building_id":"null",
        "building_name":"Off Campus Location",
        "campus_maps_id":"1",
        "room":"https:\/\/umich.zoom.us\/j\/5131037575?omn=94024500517",
        "location_name":"Virtual",
        "has_livestream":1,
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        "livestream_id":"5131037575",        
        "livestream_link":"https:\/\/umich.zoom.us\/j\/5131037575",        
        "cost":"",
        "tags":["Ai","Artificial Intelligence","Data","Data Analysis","Data Collection","Data Curation","Data Linkage","Data Management","Data Science","Great Lakes Cluster","High Performance Computing","Machine Learning","Social Science","Social Sciences","Statistics"],
        "website":"",
        "sponsors":[
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                "group_name":"Institute for Social Research",
                "group_id":"3285",
                "website":"http:\/\/isr.umich.edu"                }                    ],
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        "datetime_modified":"20260922T182157",
        "datetime_start":"20261020T100000",
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        "has_end_time":1,
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        "date_end":"2026-10-20",
        "time_start":"10:00:00",
        "time_end":"11:15:00",
        "time_zone":"America\/Detroit",
        "event_title":"2026 Ethics & Compliance Week",
        "occurrence_title":"",
        "combined_title":"2026 Ethics & Compliance Week: Multiple conference events and sessions",
        "event_subtitle":"Multiple conference events and sessions",
        "event_type":"Conference \/ Symposium",
        "event_type_id":"5",
        "description":"The Ethics, Integrity, and Compliance Office is hosting the inaugural Ethics & Compliance Week at the University of Michigan. Please join us in supporting the university through ethics and compliance educational sessions.\u00a0",
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        "room":"",
        "location_name":"2nd Floor | Pendleton Room",
        "has_livestream":0,
        "cost":"",
        "tags":["Sessions"],
        "website":"https:\/\/sessions.studentlife.umich.edu\/p\/track\/17221",
        "sponsors":[
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                "group_name":"Sessions @ Michigan",
                "group_id":"4791",
                "website":"https:\/\/sessions.studentlife.umich.edu\/"                }                    ],
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    {
        "datetime_modified":"20260824T112111",
        "datetime_start":"20261020T100000",
        "datetime_end":"20261020T113000",
        "has_end_time":1,
        "date_start":"2026-10-20",
        "date_end":"2026-10-20",
        "time_start":"10:00:00",
        "time_end":"11:30:00",
        "time_zone":"America\/Detroit",
        "event_title":"Introduction to Digital Accessibility",
        "occurrence_title":"",
        "combined_title":"Introduction to Digital Accessibility: Presenter: ITS Accessibility Team",
        "event_subtitle":"Presenter: ITS Accessibility Team",
        "event_type":"Workshop \/ Seminar",
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        "description":"Course details and registration are available on the Organizational Learning website.",
        "occurrence_notes":null,
                "guid":"150780-21910162@events.umich.edu",
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        "has_livestream":1,
        "livestream_type":"other",
        "livetream_require_login":0,
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        "cost":"",
        "tags":["Accessibility","Digital Accessibility","Information and Technology"],
        "website":"https:\/\/hr.umich.edu\/working-u-m\/professional-development\/courses\/introduction-digital-accessibility",
        "sponsors":[
             {
                "group_name":"Organizational Learning",
                "group_id":"2606",
                "website":"https:\/\/hr.umich.edu\/organizational-learning"                }                    ],
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        "datetime_modified":"20260914T165019",
        "datetime_start":"20261020T100000",
        "datetime_end":"20261020T170000",
        "has_end_time":1,
        "date_start":"2026-10-20",
        "date_end":"2026-10-20",
        "time_start":"10:00:00",
        "time_end":"17:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Pictured Rocks Fall Break",
        "occurrence_title":"",
        "combined_title":"Pictured Rocks Fall Break",
        "event_subtitle":"",
        "event_type":"Well-being",
        "event_type_id":"12",
        "description":"Pictured Rocks Fall Break is a five-day expedition from October 16\u201320, 2026.  to one of Michigan's most breathtaking landscapes during the peak of fall color.\n\nThroughout the long weekend, you'll hike through colorful autumn forests, discover hidden coves, and take in sweeping views from cliffs rising nearly 200 feet above the crystal-clear waters of Lake Superior. Register by October 6, 2026 to secure your spot! Cost: $755\n\nThis expedition offers two ways to experience Pictured Rocks. Approximately 8\u201310 participants will backpack a section of the lakeshore trail, carrying everything needed for several days in the backcountry while camping at remote sites. \n\nThe remaining participants will establish a comfortable tent basecamp, explore the region through day hikes and scenic destinations, and support the backpacking team with transportation and logistics. \n\nThe program takes place October 16\u201320, 2026. Participants will spend four nights tent camping throughout Pictured Rocks National Lakeshore before returning to the Adventure Leadership Resource Center located on Central Campus during the evening on Tuesday, October 20.\nThe program includes transportation, meals during the expedition, campsite reservations, all group camping equipment, and the opportunity to borrow personal camping gear \u2014 including a backpack, sleeping bag, sleeping pad, and headlamp \u2014 at no additional cost. Personal clothing and toiletries are not included.",
        "occurrence_notes":null,
                "guid":"152142-21913138@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/152142",
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        "building_name":"Off Campus Location",
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        "tags":["Adventure Leadership","Community","Leadership","Nature","outdoor adventures","Outdoors","recreation","Well-being","Wellness"],
        "website":"http:\/\/google.com\/url?q=https:\/\/recreation.umich.edu\/trips\/findyourtrip\/&sa=D&source=docs&ust=1789422104457078&usg=AOvVaw2fSctYMtNHkQrj7mv07HkT",
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                "group_name":"Department of Michigan Recreation",
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        "time_start":"12:00:00",
        "time_end":"16:00:00",
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        "event_title":"\u201cWho Counts? A History of Voting in America\u201d",
        "occurrence_title":"",
        "combined_title":"\u201cWho Counts? A History of Voting in America\u201d",
        "event_subtitle":"",
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        "description":"Changes over the course of the nineteenth century in how Americans voted, from voice vote to public ballot box to private voting booth, also saw changes in the material culture that surrounded voting. Ballots and ballot boxes, campaign pins and ribbons, blank lists and pre-printed party tickets, lanterns and banners\u2013the creative forces of the American print industry filled the country\u2019s cities and small towns with the ephemera of electioneering.\n\nAs you look at the items in this exhibit, think about what they tell us about how Americans in the past felt about voting, and about how voting felt. How did Election Days feel when they were full of parades and music and public drinking? What was it like to vote when everyone around you knew who you voted for? And, most of all, who counted as a voter, and who did the counting?\n\nOn view September 11-December 22, weekdays from 12-4 pm.",
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        "location_name":"William Clements Library",
        "has_livestream":0,
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        "tags":["american culture","american history","Americana","Event","Exhibit","Exhibition","history","In Person","libraries","Library","Tour","William L Clements"],
        "website":"https:\/\/clements.umich.edu\/exhibit\/who-counts\/",
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        "date_end":"2026-10-20",
        "time_start":"12:00:00",
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        "event_title":"Avoiding Assumptions & Normalizing Disability",
        "occurrence_title":"",
        "combined_title":"Avoiding Assumptions & Normalizing Disability",
        "event_subtitle":"",
        "event_type":"Workshop \/ Seminar",
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        "description":"Join this practical, perspective-shifting workshop to explore how everyday assumptions can unintentionally undermine disability inclusion. Together, we\u2019ll examine common misconceptions\u2014such as assuming someone using a mobility cane needs assistance, or that two people with the same diagnosis will have the same needs\u2014and consider how these assumptions can shape our interactions. \n\nParticipants will learn how viewing disability as a natural part of human diversity can help us respond with greater respect, awareness, and openness. This workshop offers an opportunity to reflect, challenge assumptions, and build more inclusive practices in everyday settings.\n\nAmerican Sign Language (ASL) interpreting services and Communication Access Realtime Translation (CART) captioning services will be provided. If you need additional accommodations to participate in this webinar, please email the ADA Coordinator at ADAcoordinator@umich.edu.",
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        "tags":["Accessibility","Culture","Disability","Diversity","Inclusion","Ndeam","Virtual","Workshop"],
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    {
        "datetime_modified":"20260922T121523",
        "datetime_start":"20261020T120000",
        "datetime_end":"20261020T170000",
        "has_end_time":1,
        "date_start":"2026-10-20",
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        "time_zone":"America\/Detroit",
        "event_title":"Cosmo Whyte: Under the Quiet, Beyond the Eye",
        "occurrence_title":"",
        "combined_title":"Cosmo Whyte: Under the Quiet, Beyond the Eye",
        "event_subtitle":"",
        "event_type":"Exhibition",
        "event_type_id":"7",
        "description":"\n\nCurated by Srimoyee Mitra\n\nStamps Gallery kicks off the fall 2026 semester with an ambitious mid-career survey of interdisciplinary artist Cosmo Whyte. Born and raised in Jamaica, Whyte completed a BFA from Bennington College and earned an MFA from the University of Michigan. He is currently a faculty member at the School of the Arts and Architecture, UCLA.\n\nThis exhibition brings together two central concerns that animate Whyte\u2019s artistic practice: the archive, both personal and public, as a site of disturbance; and migration as a lived experience of refuge, refusal, and reinvention. In Whyte\u2019s work, the archive is never static or neutral. Rather, it is a contested space where official histories encounter memory, inheritance, and the fragments of stories carried across generations. His practice moves within this charged interstitial terrain, between what has been recorded and what has been remembered, between institutional knowledge and embodied experience. Whyte invites the viewer to consider the fluidity of geographic borders and layered cultural identities that have persisted despite societal unrest caused by racial and socio-economic hierarchies across generations. In an era of intensified border politics and renewed debates over national identity, Whyte\u2019s work offers a timely meditation on memory, movement, and belonging.\n\nPresented with support from the U-M Institute for Humanities, the U-M LSA Center for Latin American and Caribbean Studies, and the U-M Library.",
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        "location_name":"Stamps Gallery, 201 South Division Street Ann Arbor, Michigan 48104",
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        "tags":["Art"],
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    {
        "datetime_modified":"20260917T125554",
        "datetime_start":"20261020T120000",
        "datetime_end":"20261020T130000",
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        "date_start":"2026-10-20",
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        "time_start":"12:00:00",
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        "event_title":"Woll Family Speaker Series Presents:  Dr. Nathan Houchens",
        "occurrence_title":"",
        "combined_title":"Woll Family Speaker Series Presents:  Dr. Nathan Houchens: \"Toward a More Sacred Healthcare: How Individuals, Teams, and Systems can Foster Sacred Moments\" w\/Dr. Nathan Houchens",
        "event_subtitle":"\"Toward a More Sacred Healthcare: How Individuals, Teams, and Systems can Foster Sacred Moments\" w\/Dr. Nathan Houchens",
        "event_type":"Livestream \/ Virtual",
        "event_type_id":"24",
        "description":"About This Event\nIs medicine a sacred practice? Nathan Houchens, MD, a\u202fProfessor of Internal Medicine at the University of Michigan, thinks so.\u202fAs the\u202fExecutive Director of the Sacred Moments Initiative, he leads a multidisciplinary group devoted to studying, cataloging, educating about, sharing and spreading the message of sacred moments in the clinical world. As part of that work, he\u202fhosts\u202f\u201cBoundless Moments,\u201d\u202fa storytelling podcast in which sacred moments come to life through the voices of those who lived them.\u202fHe also serves as the\u202fActing\u202fChief of Medicine at the Veterans Affairs Ann Arbor Healthcare System\u202fand the Director of the Patient Safety and Quality Improvement Learning Program\u202ffor the Internal Medicine Residency. \n\nDr. Houchens\u202fhas a wealth of experience in\u202ffacilitating\u202fcommunication skills training at the local, regional and national levels. His research and interests revolve around interpersonal relationships, connection\u202fand\u202fcommunication in healthcare settings.\u202fHe emphasizes the role communication plays in patient and provider satisfaction, education, professionalism and humanism. He has found that sacred moments in healthcare tie many of these together. He has authored\u202fmore than 90\u202fpeer-reviewed publications, one book (\"Teaching Inpatient Medicine: Connecting, Coaching, and Communicating in the Hospital, 2nd\u202fEdition\")\u202fand\u202fthree\u202fbook chapters.",
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                "guid":"152365-21913591@events.umich.edu",
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        "livestream_id":"97138636952",        
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        "tags":["Boundless Moments","Cataloging","Clinical Education","Health Care Equity","Healthcare","Healthcare Education","Humanism","Internal Medicine","Internal Medicine Residency","Learning Program","Medicine","Patient Safety","Sacred Moments Initiative","Spirituality"],
        "website":"https:\/\/medschool.umich.edu\/events\/woll-family-speaker-series\/toward-more-sacred-healthcare-how-individuals-teams-and-systems-can-foster-sacred-moments-speaker-dr\/2026-10-20",
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        "datetime_modified":"20260922T182157",
        "datetime_start":"20261020T130000",
        "datetime_end":"20261020T143000",
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        "date_end":"2026-10-20",
        "time_start":"13:00:00",
        "time_end":"14:30:00",
        "time_zone":"America\/Detroit",
        "event_title":"2026 Ethics & Compliance Week",
        "occurrence_title":"Conflict Resolution for Leaders",
        "combined_title":"2026 Ethics & Compliance Week: Multiple conference events and sessions: Conflict Resolution for Leaders",
        "event_subtitle":"Multiple conference events and sessions",
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        "event_type_id":"5",
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        "location_name":"2nd Floor | Pendleton Room",
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        "tags":["Sessions"],
        "website":"https:\/\/sessions.studentlife.umich.edu\/p\/track\/17221",
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        "event_title":"eRPM Proposal Preparation and Unit Review Class",
        "occurrence_title":"eRPM Proposal Preparation and Unit Review - 10\/20\/26",
        "combined_title":"eRPM Proposal Preparation and Unit Review Class: eRPM Proposal Preparation and Unit Review - 10\/20\/26",
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        "description":"This instructor-led, hands-on training session covers the process of preparing and submitting proposals using the eResearch Proposal Management (eRPM) system, including Grants.gov to create and edit a Proposal Approval Form (PAF).",
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    {
        "datetime_modified":"20260921T164909",
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        "event_title":"Positive Links Speaker Series",
        "occurrence_title":"",
        "combined_title":"Positive Links Speaker Series: The Power of Beliefs: How Seven Core Beliefs Shape Performance, Well-Being, and Collective Thriving",
        "event_subtitle":"The Power of Beliefs: How Seven Core Beliefs Shape Performance, Well-Being, and Collective Thriving",
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        "event_title":"The Distribution of Federally-Insured Mortgages, 1935-1975: Evidence from Local Land Records (with Jacob Faber, Andreas Ferrara, Jonathan Rose, Thomas Storrs, Katherine Thomas, Gabrielle Toborg, Randall Walsh, and Wenfei Xu)",
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        "datetime_modified":"20260922T101958",
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        "event_title":"History in a Time of Forgetting",
        "occurrence_title":"",
        "combined_title":"History in a Time of Forgetting",
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        "description":"What do we \u2014 as individuals, communities, and members of a nation \u2014 choose to remember? What, or who, is erased from accounts of our shared past? And who benefits from the official and unofficial narratives constructed about the nation\u2019s collective history? \n\nIn 2026, as the country celebrates the 250th anniversary of the signing of the Declaration of Independence, the current presidential administration has taken concerted steps to shape and disseminate a very specific version of the nation\u2019s history. Notably, their efforts involve limiting the stories that are told about our past to conceal difficult truths, ignoring real complexities from the historical record, undermining the difficult work of historical research, and seeking to avoid the processes of interpreting and discussing the meaning of our past. But we can also see the resistance to this rewriting and its erasures in the persistence of existing histories, as well as the continued proliferation of alternate histories in a variety of spheres and locations that are not subject to governmental control.\n\nThis webinar accompanies the publication of Spark Magazine\u2019s upcoming series, \u201cHistory in a Time of Forgetting,\u201d which grapples with what it means to engage in and uplift historical research amid the present national climate. The online webinar will feature series curators Jennifer Brady and Camron Michael Amin, from the University of Michigan's Inclusive History Project, in conversation with series contributors Elisa Alfonso, David Porter, S. Shani Saunders, and Tenisha Tevis. These writers take a range of approaches to history and remembering, exploring pop culture analysis, community storykeeping, personal history, and public pedagogy.",
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        "tags":["AEM Featured"],
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        "event_title":"Mechanistic Insights into Metal-Protein Interactions: Implications for Neurodegenerative Disease Progression and Intervention",
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        "combined_title":"Mechanistic Insights into Metal-Protein Interactions: Implications for Neurodegenerative Disease Progression and Intervention: Katlyn Meier | University of Miami",
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        "description":"Elevated levels of protein expression and aberrant metal exposure have been reported in many neurodegenerative diseases, including Huntington\u2019s Disease (HD). While there is currently no cure for HD, metal chelation therapies have been shown to assuage disease symptoms including chorea. These observations underscore the critical need to understand how metal-protein interactions are involved in disease pathogenesis. Our objective in this work is to elucidate the role of copper (Cu) and other biorelevant metals in HD and, more specifically, their interactions with the huntingtin protein (htt). We aimed to characterize the Cu-htt interaction and speciation trends in our in vitro HD system, as well as the influence of disease-relevant Cu concentrations on protein oligomerization\/aggregation both in vitro and in vivo. We utilized multiple spectroscopic techniques (circular dichroism, electron paramagnetic resonance, UV-Vis absorption, dynamic light scattering, and mass spectrometry) that cover a broad range of energy scales, allowing us to characterize protein structure at the molecular, secondary structure, and quaternary structure levels. Additionally, site-directed mutagenesis of several putative metal binding residues was used to define the roles of specific amino acids in mediating oligomerization\/aggregation, metal binding, and redox chemistry. Taken together, our work has led to the first report of multiple copper binding sites in non-pathological htt and provides insight into one pathway for depletion of native htt pools that may contribute to HD.",
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