{ "133612-21873303": { "datetime_modified":"20250310T090903", "datetime_start":"20250408T120000", "datetime_end":"20250408T130000", "has_end_time":1, "date_start":"2025-04-08", "date_end":"2025-04-08", "time_start":"12:00:00", "time_end":"13:00:00", "time_zone":"America\/Detroit", "event_title":"Elliot S. Valenstein Distinguished Lecture | Synapse Specific Structural Plasticity: A Cellular Mechanism of Spaced Learning", "occurrence_title":"", "combined_title":"Elliot S. Valenstein Distinguished Lecture | Synapse Specific Structural Plasticity: A Cellular Mechanism of Spaced Learning: Kristen Harris, Professor of Neuroscience at the University of Texas at Austin", "event_subtitle":"Kristen Harris, Professor of Neuroscience at the University of Texas at Austin", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"Synapses form trillions of connections in the brain. Long-term potentiation (LTP) is a cellular mechanism vital for learning that modifies the strength and structure of synapses. Three-dimensional electron microscopy reveals distinct pre- to post-synaptic arrangements: strong active zones (AZs) with tightly docked vesicles, weak AZs with loose or non-docked vesicles, and nascent zones (NZs) with a postsynaptic density but no presynaptic vesicles. LTP can be temporarily saturated preventing further increases in synaptic strength. I will discuss how NZ plasticity provides a time dependent and synapse-specific AZ expansion during LTP that ultimately encourages highly effective dendritic spine clusters regulated by the spine apparatus. I will also tell you why we have developed a new synaptopodin knockout rat system to investigate mechanisms of this process. We propose that the saturation of LTP protects recently formed memories and that the regrowth of nascent zones may account for the advantage of spaced over massed learning.\r\n\r\nAbout the speaker: Kristen Harris\u2019s professional career started at Harvard Medical school where she rose to the rank of associate professor. She was the recruited as a full Professor to Boston Univ. where she helped establish their graduate program in experimental and computational neuroscience. She was recruited as a Georgia Research Alliance Eminent scholar to the Medical College of Georgia, and in 2006 joined the Center for Learning and Memory at the University of Texas at Austin. She is renowned for her work on synapse structure and function pioneering three-dimensional reconstruction from serial section electron microscopy. Her lab had developed novel tools sharing them and data (synapseweb.clm.utexas.edu) that are widely used resources. She is the recipient of Sloan Research Fellowship, Javits Merit Award, Brain Research Foundation Fellowship, and continuous funding for her lab, including her current lead as PI on the NSF NeuroNex grant to investigate synaptic weight with 26 international and national coPIs. She is known for innovative teaching and presentations at conferences worldwide. She was recently elected to the National Academy of Sciences.\r\n\r\nThe talk will be followed by a reception with light refreshments.", "occurrence_notes":null, "guid":"133612-21873303@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/133612", "building_id":"1000166", "building_name":"East Hall", "campus_maps_id":"53", "room":"4448", "location_name":"East Hall", "has_livestream":0, "cost":"", "tags":["Neuroscience","Psychology"], "website":"", "sponsors":[ { "group_name":"Department of Psychology", "group_id":"3615", "website":"http:\/\/www.lsa.umich.edu\/psych\/" }, { "group_name":"Brain & Behavior", "group_id":"3662", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2025\/03\/event_133612_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2025\/03\/event_133612_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2025\/03\/event_133612_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2025\/03\/event_133612_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2025\/03\/event_133612_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2025\/03\/event_133612_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2025\/03\/event_133612_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2025\/03\/event_133612_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large_lightbox\/media\/attachments\/2025\/03\/event_133612_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2025\/03\/event_133612_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2025\/03\/event_133612_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2025\/03\/event_133612_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2025\/03\/event_133612_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2025\/03\/event_133612_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_large\/media\/attachments\/2025\/03\/event_133612_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2025\/03\/event_133612_original-1.png" }, "occurrence_count":1, "first_occurrence":21873303 } , "134413-21874331": { "datetime_modified":"20250511T155034", "datetime_start":"20250408T120000", "datetime_end":"20250408T140000", "has_end_time":1, "date_start":"2025-04-08", "date_end":"2025-04-08", "time_start":"12:00:00", "time_end":"14:00:00", "time_zone":"America\/Detroit", "event_title":"Graduate and Professional Student Appreciation Week: Grad Grub", "occurrence_title":"", "combined_title":"Graduate and Professional Student Appreciation Week: Grad Grub", "event_subtitle":"", "event_type":"Social \/ Informal Gathering", "event_type_id":"19", "description":"Take a break and grab some delicious food at Grad Grub, a special food truck rally in celebration of National Graduate and Professional Student Appreciation Week! Stop by to pick up a voucher and enjoy a meal from one of the featured food trucks:\n\n\nWhoa! Tacos\n\n\nWanderbowls\n\n\nLittle Caesars\n\n\nA tent will be set up outside for shade and shelter, and the East and West Conference Rooms on the 4th floor of Rackham will be available for additional seating and weather protection.\nAs a bonus, attendees will receive a cozy Rackham-branded crewneck sweatshirt, while supplies last.\nCome for the food, stay for the fun, and celebrate with your fellow graduate and professional students!\nRegistration is encouraged at https:\/\/myumi.ch\/4mdZA.\nWe want to ensure full and equitable participation in our events. If an accommodation would promote your full participation in this event, please follow the registration link to indicate your accommodation requirements. Please let us know as soon as possible in order to have adequate time, preferably one week, to arrange for your requested accommodations or an effective alternative.", "occurrence_notes":null, "guid":"134413-21874331@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/134413", "building_id":"0", "building_name":"Ingalls Mall", "campus_maps_id":"558", "room":"", "location_name":"Ingalls Mall", "has_livestream":0, "cost":"", "tags":["Graduate Students"], "website":"https:\/\/rackham.umich.edu\/event\/graduate-and-professional-student-appreciation-week-grad-grub\/", "sponsors":[ { "group_name":"Rackham Graduate School", "group_id":"1187", "website":"https:\/\/www.facebook.com\/umichgradschool" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21874331 } , "132404-21870888": { "datetime_modified":"20250205T181823", "datetime_start":"20250408T120000", "datetime_end":"20250408T123000", "has_end_time":1, "date_start":"2025-04-08", "date_end":"2025-04-08", "time_start":"12:00:00", "time_end":"12:30:00", "time_zone":"America\/Detroit", "event_title":"Kathy Beck, carillon", "occurrence_title":"", "combined_title":"Kathy Beck, carillon", "event_subtitle":"", "event_type":"Performance", "event_type_id":"15", "description":"Kathy Beck performs on the Charles Baird Carillon, an instrument of 53 bronze bells located inside the Burton Memorial Tower. The largest bell, which strikes the hour, weighs 12 tons, while the smallest bell, 4\u00bd octaves above, weighs just 15 pounds.\n\nThirty-minute recitals are performed on the Charles Baird\u00a0Carillon\u00a0at noon every weekday that classes are in session, followed by visitor Q&A with the carillonist.\u00a0The bell chamber may be accessed via a combination of elevator and stairs. Take the elevator to the highest floor possible (floor 8), and then climb two flights of stairs (39 steps) to the bell chamber (floor 10). Hearing protection earmuffs are provided for visitors. Be prepared to walk on ice and snow in the bell chamber during winter.\u00a0Built in 1936, the Charles Baird\u00a0Carillon\u00a0is not ADA accessible. Visitors with mobility concerns are invited to\u00a0visit the Lurie\u00a0Carillon.", "occurrence_notes":null, "guid":"132404-21870888@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/132404", "building_id":"1000155", "building_name":"Burton Memorial Tower", "campus_maps_id":"25", "room":"", "location_name":"Burton Memorial Tower", "has_livestream":0, "cost":"Free - no tickets required", "tags":["Free","Music","Talk"], "website":"", "sponsors":[ { "group_name":"School of Music, Theatre & Dance (SMTD)", "group_id":"155", "website":"http:\/\/smtd.umich.edu\/events" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2025\/02\/event_132404_original-1.jpg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_thumb\/media\/attachments\/2025\/02\/event_132404_original-1.jpg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2025\/02\/event_132404_original-1.jpg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_2x\/media\/attachments\/2025\/02\/event_132404_original-1.jpg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2025\/02\/event_132404_original-1.jpg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2025\/02\/event_132404_original-1.jpg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2025\/02\/event_132404_original-1.jpg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2025\/02\/event_132404_original-1.jpg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large_lightbox\/media\/attachments\/2025\/02\/event_132404_original-1.jpg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2025\/02\/event_132404_original-1.jpg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2025\/02\/event_132404_original-1.jpg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2025\/02\/event_132404_original-1.jpg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2025\/02\/event_132404_original-1.jpg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2025\/02\/event_132404_original-1.jpg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_large\/media\/attachments\/2025\/02\/event_132404_original-1.jpg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_thumb\/media\/attachments\/2025\/02\/event_132404_original-1.jpg" }, "occurrence_count":1, "first_occurrence":21870888 } }