{ "128764-21861599": { "datetime_modified":"20241205T063119", "datetime_start":"20241120T110000", "datetime_end":"20241120T120000", "has_end_time":1, "date_start":"2024-11-20", "date_end":"2024-11-20", "time_start":"11:00:00", "time_end":"12:00:00", "time_zone":"America\/Detroit", "event_title":"Articulating and Leveraging Your Transferable Skills", "occurrence_title":"", "combined_title":"Articulating and Leveraging Your Transferable Skills", "event_subtitle":"", "event_type":"Careers \/ Jobs", "event_type_id":"2", "description":"In partnership with Rackham Graduate school, The topic forthis session is transferable skills -- translating skills you've gained during graduate school to the job market. We\u2019ll spend the first few minutes reviewing transferable skills, and the remainder of the session discussing different types of graduate school experiences, with a focus on articulating the transferable skills gained from these experiences. To get themost out of the session, please come prepared with questions and\/or experiences to share. This event is intended to be interactive and therefore arecording will not be available.", "occurrence_notes":null, "guid":"128764-21861599@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/128764", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"", "has_livestream":0, "cost":"", "tags":[], "website":"", "sponsors":[ { "group_name":"University Career Center UCC", "group_id":"1140", "website":"http:\/\/careercenter.umich.edu" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21861599 } , "128511-21861057": { "datetime_modified":"20241030T091958", "datetime_start":"20241120T110000", "datetime_end":"20241120T190000", "has_end_time":1, "date_start":"2024-11-20", "date_end":"2024-11-20", "time_start":"11:00:00", "time_end":"19:00:00", "time_zone":"America\/Detroit", "event_title":"Beautiful Works of Art - Student Art Exhibition", "occurrence_title":"", "combined_title":"Beautiful Works of Art - Student Art Exhibition", "event_subtitle":"", "event_type":"Exhibition", "event_type_id":"7", "description":"Join us in our 4th floor Atrium to view our next student art exhibition, Beautiful Works of Art. This exhibition showcases favorite pieces of art from 5 undergraduate students from the Stamps School of Art & Design. Each artist brings her unique style to the exhibit with works spanning painting, illustration and multimedia. \r\n\r\nThe exhibition will be on display from October 31 - November 27.\r\n\r\nArtists include Cate Bennett, Georgia Gutkin, Chloe Kreindler, Meggie Kennedy & Brianna Sorkin", "occurrence_notes":null, "guid":"128511-21861057@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/128511", "building_id":"1005047", "building_name":"Palmer Commons", "campus_maps_id":"188", "room":"4th Floor Atrium", "location_name":"Palmer Commons", "has_livestream":0, "cost":"", "tags":["Arts","Art","Visual Arts","Palmercommons","Free","Exhibition","Culture"], "website":"", "sponsors":[ { "group_name":"Palmer Commons", "group_id":"3423", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2024\/10\/event_128511_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2024\/10\/event_128511_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2024\/10\/event_128511_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2024\/10\/event_128511_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2024\/10\/event_128511_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2024\/10\/event_128511_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2024\/10\/event_128511_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2024\/10\/event_128511_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2024\/10\/event_128511_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2024\/10\/event_128511_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2024\/10\/event_128511_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2024\/10\/event_128511_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2024\/10\/event_128511_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2024\/10\/event_128511_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2024\/10\/event_128511_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2024\/10\/event_128511_original-1.png" }, "occurrence_count":28, "first_occurrence":21861037 } , "129010-21862017": { "datetime_modified":"20241111T120336", "datetime_start":"20241120T110000", "datetime_end":"20241120T120000", "has_end_time":1, "date_start":"2024-11-20", "date_end":"2024-11-20", "time_start":"11:00:00", "time_end":"12:00:00", "time_zone":"America\/Detroit", "event_title":"DCMB \/ CCMB Weekly Seminar featuring Jennifer Phillips-Cremins, PhD (of University of Pennsylvania)", "occurrence_title":"", "combined_title":"DCMB \/ CCMB Weekly Seminar featuring Jennifer Phillips-Cremins, PhD (of University of Pennsylvania): Talk title: \"The Science of Connections: Bridging chromatin, synaptic plasticity, and neurophysiology\"", "event_subtitle":"Talk title: \"The Science of Connections: Bridging chromatin, synaptic plasticity, and neurophysiology\"", "event_type":"Livestream \/ Virtual", "event_type_id":"24", "description":"Abstract:\r\n\r\nThe Cremins Laboratory works at the spatial biology-technology interface to investigate the structure-function relationship of connections in the brain across the scales of chromatin, synapses, and circuits in normal neurophysiology and in neurological disorders. We have thus far focused in the nucleus on creating kilobase-resolution maps of higher-order folding of the chromatin fiber and understanding how classic epigenetic modifications work through long-range connections to govern genome function in neurodevelopment. We have developed and applied new molecular and computational technologies to elucidate chromatin folding patterns at kilobase-resolution genome-wide, thus discovering that long-range looping interactions in cis and inter-chromosomal interactions in trans change substantially during neural lineage commitment, somatic cell reprogramming, activation of post-mitotic neural circuits, and in neurological disorders. We have demonstrated that cohesin-mediated loops are necessary for the establishment of new gene expression programs in post-mitotic neurons, including the upregulation of genes encoding axon guidance, dendritic spine morphology, and synaptic plasticity during neuron maturation in vivo as well as activity-dependent transcription during neural stimulation in vitro. We have also identified cohesin-mediated loops anchored by divergently-oriented CTCF binding sites that are necessary and sufficient for the firing efficiency and localization of human replication origins during S phase re-entry after mitosis. Using fragile X syndrome as a natural perturbation, we have uncovered BREACHes (Beacons of Repeat Expansion Anchored by Contacting Heterochromatin) - rare inter-chromosomal interactions connecting heterochromatinized synaptic genes susceptible to repeat instability, thus providing early insight into the genome\u2019s structure-function relationship. Here, I will present new unpublished data describing 3D genome miswiring in a human neuron model with rare familial Alzheimer\u2019s mutations as well as the functional link among loops and activity-dependent gene expression during neural circuit activation in vitro and in vivo. The long-term goal of the Cremins lab is to elucidate how the genome\u2019s structure-function relationship influences synaptic plasticity and neurophysiology during memory encoding and consolidation and how this goes awry in intractable neurological disorders. \r\n\r\nBio:\r\n\r\nJennifer Phillips-Cremins, Ph.D. is an Associate Professor and Deans' Faculty Fellow in Engineering and Medicine at the University of Pennsylvania with primary appointments in the Departments of Genetics and Bioengineering. Dr. Cremins obtained her Ph.D. in Biomedical Engineering from the Georgia Institute of Technology in the laboratory of Andres Garcia. She conducted a multi-disciplinary postdoc in the laboratories of Job Dekker and Victor Corces. Dr. Cremins runs the Laboratory of Chromatin and Spatial Neurobiology at UPenn. Her primary research interests lie in understanding the long-range chromatin architecture mechanisms that govern neural specification and synaptic plasticity in healthy neurons and how chromatin-synapse communication is dysregulated in neurodevelopmental and neurodegenerative diseases. She has been selected as a 2014 New York Stem Cell Foundation Robertson Investigator, a 2015 Albert P. Sloan Foundation Fellow, a 2016 and 2018 Kavli Frontiers of Science Fellow, 2015 NIH Director's New Innovator Awardee, 2020 NSF CAREER Awardee, a 2020 CZI Neurodegenerative Disease Pairs Awardee, the 2022 ISSCR Susan B. Lim Outstanding New Investigator Award, and as a recipient of the 2021 NIH Pioneer Award.", "occurrence_notes":null, "guid":"129010-21862017@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/129010", "building_id":"1005047", "building_name":"Palmer Commons", "campus_maps_id":"188", "room":"Forum Hall", "location_name":"Palmer Commons", "has_livestream":0, "cost":"", "tags":["Learning Health Systems","Virtual","Lecture","Life Science","Mathematics","Medicine","Michigan Engineering","Pediatrics","Physics","Precision Health","Public Health","Research","Science","seminar","Structural Biology","Talk","Undergraduate","Discussion","Applications","Basic Science","Biointerfaces","Biology","Biomedical Engineering","Biosciences","Cardiovascular","Chemistry","Information and Technology","Education","Electrical Engineering and Computer Science","Engineering","Free","Graduate Students","Human Genetics","In Person"], "website":"https:\/\/medschool.umich.edu\/events\/ccmb-seminar-series\/ccmb-seminar-jennifer-e-phillips-cremins-phd\/2024-11-20", "sponsors":[ { "group_name":"DCMB Seminar Series", "group_id":"3754", "website":"" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21862017 } }