{ "125102-21854410": { "datetime_modified":"20250320T143910", "datetime_start":"20250415T160000", "datetime_end":"", "has_end_time":0, "date_start":"2025-04-15", "date_end":"", "time_start":"16:00:00", "time_end":"", "time_zone":"America\/Detroit", "event_title":"From Helicases to CRISPR: How RNA Stability and Specificity Shape Biology", "occurrence_title":"", "combined_title":"From Helicases to CRISPR: How RNA Stability and Specificity Shape Biology: Rick Russell (UT Austin)", "event_subtitle":"Rick Russell (UT Austin)", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"The fundamental properties of the RNA double helix\u2014high structural stability and strict base-pairing specificity\u2014have profoundly influenced biological systems throughout evolutionary history and up to today. While the stability allows helices to serve as rigid scaffolds within structured RNAs, it also creates significant energetic barriers to rearrangement, necessitating RNA helicases as chaperones in RNA folding and remodeling. At the same time, the high specificity of Watson-Crick base pairing enables RNA-guided mechanisms, exemplified by CRISPR-Cas enzymes that leverage this specificity for DNA targeting. This talk will explore how these core biophysical properties have shaped RNA\u2019s biological roles, driven evolution of protein families, and enabled modern genome-editing tools.", "occurrence_notes":null, "guid":"125102-21854410@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/125102", "building_id":"1000158", "building_name":"Chemistry Dow Lab", "campus_maps_id":"34", "room":"1640", "location_name":"Chemistry Dow Lab", "has_livestream":0, "cost":"", "tags":["Chemistry","Chemical Biology"], "website":"https:\/\/molecularbiosci.utexas.edu\/directory\/rick-russell", "sponsors":[ { "group_name":"Department of Chemistry", "group_id":"3761", "website":"https:\/\/lsa.umich.edu\/chem" }, { "group_name":"LSA Biophysics", "group_id":"3767", "website":"" }, { "group_name":"Chemical Biology", "group_id":"4385", "website":"" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21854410 } , "131291-21868121": { "datetime_modified":"20250121T100030", "datetime_start":"20250415T160000", "datetime_end":"20250415T170000", "has_end_time":1, "date_start":"2025-04-15", "date_end":"2025-04-15", "time_start":"16:00:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"German Convo on the Go", "occurrence_title":"", "combined_title":"German Convo on the Go", "event_subtitle":"", "event_type":"Social \/ Informal Gathering", "event_type_id":"19", "description":"Members of the U-M community can walk and talk in German with Mary Gell (magell@umich.edu), German language instructor. Meet at Burton Tower, 'rain or shine', for a 1-hour walk. If the temperature is dangerously low, this event will meet in room 3110 Modern Languages Building. Please contact Mary if you have questions. Note that the group leaves at 4pm sharp.", "occurrence_notes":"Group leaves at 4pm sharp.", "guid":"131291-21868121@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/131291", "building_id":"1000155", "building_name":"Burton Memorial Tower", "campus_maps_id":"25", "room":"", "location_name":"Burton Memorial Tower", "has_livestream":0, "cost":"", "tags":["Germanic Languages And Literatures","German Studies","German"], "website":"", "sponsors":[ { "group_name":"Germanic Languages & Literatures", "group_id":"3621", "website":"http:\/\/www.facebook.com\/umichGerman\/" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2025\/01\/event_131291_original-1.jpg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2025\/01\/event_131291_original-1.jpg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2025\/01\/event_131291_original-1.jpg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2025\/01\/event_131291_original-1.jpg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2025\/01\/event_131291_original-1.jpg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2025\/01\/event_131291_original-1.jpg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2025\/01\/event_131291_original-1.jpg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2025\/01\/event_131291_original-1.jpg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2025\/01\/event_131291_original-1.jpg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2025\/01\/event_131291_original-1.jpg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2025\/01\/event_131291_original-1.jpg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2025\/01\/event_131291_original-1.jpg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2025\/01\/event_131291_original-1.jpg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2025\/01\/event_131291_original-1.jpg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2025\/01\/event_131291_original-1.jpg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2025\/01\/event_131291_original-1.jpg" }, "occurrence_count":12, "first_occurrence":21868109 } , "98429-21864889": { "datetime_modified":"20241211T161203", "datetime_start":"20250415T160000", "datetime_end":"20250415T170000", "has_end_time":1, "date_start":"2025-04-15", "date_end":"2025-04-15", "time_start":"16:00:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"Newnan Info Session for LSA + School of Information Multiple Dependent Degree Program (MDDP)", "occurrence_title":"", "combined_title":"Newnan Info Session for LSA + School of Information Multiple Dependent Degree Program (MDDP)", "event_subtitle":"", "event_type":"Livestream \/ Virtual", "event_type_id":"24", "description":"Want to learn more about earning a dual undergraduate degree between LSA and the School of Information (SI)? This session is for you, whether you are currently an SI student or a Newnan-advised LSA student.\r\n\r\nStudents interested in exploring or declaring a dual degree between LSA and SI should attend one of these group info sessions to get started. This session will also cover instructions on how to schedule an advising appointment for more individualized support.\r\n\r\nPlease note: students arriving more than 5 minutes after the session start time will not be admitted.", "occurrence_notes":"If you are more than 5 minutes late, you will not be admitted.", "guid":"98429-21864889@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/98429", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Virtual", "has_livestream":1, "livestream_type":"zoom", "livetream_require_login":0, "livestream_id":"9896895189", "livestream_link":"https:\/\/umich.zoom.us\/j\/9896895189", "cost":"", "tags":["Advising","Information and Technology","Newnan"], "website":"", "sponsors":[ { "group_name":"LSA MDDP (Joint Degree) Info Sessions", "group_id":"4728", "website":"" }, { "group_name":"SAA", "group_id":"3442", "website":"" }, { "group_name":"Newnan LSA Academic Advising Center", "group_id":"3721", "website":"" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":17, "first_occurrence":21825344 } }