{ "123501-21851005": { "datetime_modified":"20240814T121111", "datetime_start":"20240903T160000", "datetime_end":"20240903T170000", "has_end_time":1, "date_start":"2024-09-03", "date_end":"2024-09-03", "time_start":"16:00:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"Math & MCAIM Colloquium: Homogenization of kirigami and origami-based mechanical metamaterials", "occurrence_title":"", "combined_title":"Math & MCAIM Colloquium: Homogenization of kirigami and origami-based mechanical metamaterials: Ian Tobasco (Rutgers)", "event_subtitle":"Ian Tobasco (Rutgers)", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Mechanical metamaterials are many-body elastic systems that deform in unusual ways, due to the interactions of nearly rigid building blocks. Examples include origami patterns with many folds, or kirigami patterns made by cutting material from an elastic sheet. In either case, the local deformations of the pattern involve internal degrees of freedom which must be matched with the usual global Euclidean invariances \u2014 e.g., groups of origami panels move by coordinated rotations and translations, but it is still possible to bend the whole pattern into a curved shape. This talk will introduce the homogenization problem for kirigami and origami metamaterials to a broad audience, and describe our recent results. Our goal is to explain the link between the design of the individual cuts\/folds and the bulk deformations they produce. This is joint work with Paul Plucinsky (U. Southern California, Aerospace and Mechanical Engineering) and Paolo Celli (Stony Brook U., Civil Engineering).\r\n\r\nThis talk will be mathematically self-contained, not assuming a background in elasticity.\r\n\r\nEvent will be in-person and on Zoom: https:\/\/umich.zoom.us\/j\/98734707290", "occurrence_notes":null, "guid":"123501-21851005@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/123501", "building_id":"1000166", "building_name":"East Hall", "campus_maps_id":"53", "room":"1360", "location_name":"East Hall", "has_livestream":0, "cost":"", "tags":["AEM Featured","Mathematics"], "website":"https:\/\/sites.lsa.umich.edu\/mcaim\/", "sponsors":[ { "group_name":"Colloquium Series - Department of Mathematics", "group_id":"4884", "website":"" }, { "group_name":"Department of Mathematics", "group_id":"3791", "website":"" }, { "group_name":"MCAIM - Department of Mathematics", "group_id":"4897", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2024\/08\/event_123501_original-1.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2024\/08\/event_123501_original-1.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2024\/08\/event_123501_original-1.jpeg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2024\/08\/event_123501_original-1.jpeg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2024\/08\/event_123501_original-1.jpeg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2024\/08\/event_123501_original-1.jpeg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2024\/08\/event_123501_original-1.jpeg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2024\/08\/event_123501_original-1.jpeg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2024\/08\/event_123501_original-1.jpeg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2024\/08\/event_123501_original-1.jpeg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2024\/08\/event_123501_original-1.jpeg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2024\/08\/event_123501_original-1.jpeg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2024\/08\/event_123501_original-1.jpeg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2024\/08\/event_123501_original-1.jpeg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2024\/08\/event_123501_original-1.jpeg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2024\/08\/event_123501_original-1.jpeg" }, "occurrence_count":1, "first_occurrence":21851005 } , "125054-21854298": { "datetime_modified":"20240827T112354", "datetime_start":"20240903T160000", "datetime_end":"", "has_end_time":0, "date_start":"2024-09-03", "date_end":"", "time_start":"16:00:00", "time_end":"", "time_zone":"America\/Detroit", "event_title":"Protein dynamics: Connecting in vitro, in cell, and in vivo", "occurrence_title":"", "combined_title":"Protein dynamics: Connecting in vitro, in cell, and in vivo: Caitlin Davis (Yale)", "event_subtitle":"Caitlin Davis (Yale)", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Our current understanding of in vitro protein folding is due to decades of experimental and computational research that provided high-resolution characterization of protein structure, identification of folding principles, and development of folding algorithms. This research has benefited scientists broadly. For example, machine learning can now predict a protein\u2019s 3D shape from its amino-acid sequence, proteins can be designed de novo for a specific fold or function, and supercomputers can simulate milliseconds of protein dynamics with all-atom resolution. With the success of in vitro studies, it is essential that we now turn our attention in vivo. While evidence that the cellular environment perturbs protein behaviors emerged over half a century ago, we still have limited fundamental information about the effects of these cooperative cellular interactions on protein properties. The gap in knowledge is largely attributable to the transient nature of interactions in the cellular milieu and challenges associated with studying protein structure, stability, and dynamics in living cells. Here we leverage groundbreaking spectro-microscopy methods, fast relaxation fluorescence imaging (FReI) and optical photothermal infrared imaging (O-PTIR) in combination with functional biochemical assays, in vitro biophysical spectroscopy, and numerical analysis solutions, to characterize in-cell protein dynamics. Our work addresses the following questions: 1. What is the physiochemical code to protein folding? Do classic in vitro protein principles translate to cells? 2. Can we develop methods to visualize the spatial distribution of metabolism and associated metabolic protein structural dynamics in living cells? 3. How does thermal adaptation and acclimation by organisms change the stability, folding, and aggregation of proteins in differentiated tissues? Overall, this work will lead to a greater understanding of protein homeostasis in health and disease.", "occurrence_notes":null, "guid":"125054-21854298@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/125054", "building_id":"1000158", "building_name":"Chemistry Dow Lab", "campus_maps_id":"34", "room":"1640", "location_name":"Chemistry Dow Lab", "has_livestream":0, "cost":"", "tags":["Chemical Biology","Chemistry"], "website":"https:\/\/chem.yale.edu\/faculty\/caitlin-davis", "sponsors":[ { "group_name":"Department of Chemistry", "group_id":"3761", "website":"https:\/\/lsa.umich.edu\/chem" }, { "group_name":"LSA Biophysics", "group_id":"3767", "website":"" }, { "group_name":"Chemical Biology", "group_id":"4385", "website":"" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21854298 } , "125189-21854515": { "datetime_modified":"20240828T101738", "datetime_start":"20240903T170000", "datetime_end":"20240903T180000", "has_end_time":1, "date_start":"2024-09-03", "date_end":"2024-09-03", "time_start":"17:00:00", "time_end":"18:00:00", "time_zone":"America\/Detroit", "event_title":"24-25 Board Fellows Program Info Session", "occurrence_title":"", "combined_title":"24-25 Board Fellows Program Info Session", "event_subtitle":"", "event_type":"Presentation", "event_type_id":"16", "description":"Business+Impact\u2019s Nonprofit Board Fellowship Program places top graduate students as non-voting members on boards at Southeast Michigan nonprofits. An application for the program is available on our website, and is due Fri, Sept 6 at Noon.\r\n\r\nYou must attend an info session like this one in order to apply to participate in the program for 2024-25.\r\n\r\nFellows can provide valuable capacity in strategic adaptation, fund development, sustainability strategies, business plans, and dashboards. Session attendees will learn about the program and hear from former participants.", "occurrence_notes":null, "guid":"125189-21854515@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/125189", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Virtual", "has_livestream":1, "livestream_type":"other", "livetream_require_login":0, "livestream_id":"", "livestream_link":"", "cost":"", "tags":["Social Impact"], "website":"https:\/\/docs.google.com\/forms\/d\/e\/1FAIpQLScBYJgIt4cKXHnRI1aEOHehmjJT__Kw9WBufng64LfQzItjfQ\/viewform", "sponsors":[ { "group_name":"Business+Impact at Michigan Ross", "group_id":"4222", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2024\/08\/event_125189_original-1.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2024\/08\/event_125189_original-1.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2024\/08\/event_125189_original-1.jpeg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2024\/08\/event_125189_original-1.jpeg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2024\/08\/event_125189_original-1.jpeg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2024\/08\/event_125189_original-1.jpeg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2024\/08\/event_125189_original-1.jpeg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2024\/08\/event_125189_original-1.jpeg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2024\/08\/event_125189_original-1.jpeg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2024\/08\/event_125189_original-1.jpeg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2024\/08\/event_125189_original-1.jpeg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2024\/08\/event_125189_original-1.jpeg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2024\/08\/event_125189_original-1.jpeg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2024\/08\/event_125189_original-1.jpeg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2024\/08\/event_125189_original-1.jpeg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2024\/08\/event_125189_original-1.jpeg" }, "occurrence_count":3, "first_occurrence":21854514 } }