{ "114673-21833285": { "datetime_modified":"20231031T102006", "datetime_start":"20231206T160000", "datetime_end":"20231206T170000", "has_end_time":1, "date_start":"2023-12-06", "date_end":"2023-12-06", "time_start":"16:00:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"Weekly DCMB \/ CCMB Seminar Series", "occurrence_title":"", "combined_title":"Weekly DCMB \/ CCMB Seminar Series: Keynote: Nathan E. Hudson, PhD, \"Probing the polymerization and structure of a blood clot\"", "event_subtitle":"Keynote: Nathan E. Hudson, PhD, \"Probing the polymerization and structure of a blood clot\"", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"Abstract:\r\nHeart attack, ischemic stroke, and venous thromboembolism are leading causes of death and disability worldwide and often result from aberrant blood clotting. Fibrin is a hierarchical biomaterial that forms the structural backbone of blood clots during the hemostatic process. Clots form when individual fibrin molecules polymerize into linear fibers which then branch into a 3-D gel at sites of injuries. These fibrin networks trap red blood cells and other vascular constituents during the wound healing process. \r\n\r\nUsing a suite of biophysical approaches, we probe the multiscale formation and structure of fibrin networks. At the molecular scale we establish that individual fibrin molecules are not rigid but adapt multiple conformations that likely assist in polymerization. At the fiber scale, we quantify the processes that govern gelation. Moreover, we demonstrate that fibers exhibit remarkable elastic properties that enable the clot to hold together, even under high tension. At the network scale we reveal how relative changes in the initial concentrations of blood clot components result in remarkably different gel structures.\r\n\r\nTaken together, these results provide a wholistic framework for understanding the mechanisms that that determine blood clot structures and linking alterations in these processes to pathologies.\r\n\r\nhttps:\/\/umich-health.zoom.us\/j\/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09\r\n\r\nResearch Projects:\r\nNathan Hudson studies the exciting field of molecular biophysics. Work in the Hudson lab uses techniques including protein engineering, centrifuge force microscopy, FRET and microfluidics to understand how mechanical force regulates biological function. Projects involve measuring the biomechanical properties of blood coagulation proteins and determining the force-depending binding kinetics of adhesion molecules. There are both graduate- and undergraduate-level projects in the lab and numerous students have won awards for their research with Dr. Hudson.", "occurrence_notes":"https:\/\/umich-health.zoom.us\/j\/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09", "guid":"114673-21833285@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/114673", "building_id":"1005047", "building_name":"Palmer Commons", "campus_maps_id":"188", "room":"Forum Hall", "location_name":"Palmer Commons", "has_livestream":0, "cost":"", "tags":["Basic Science","Talk","Structural Biology","seminar","Science","Research","Public Health","Precision Health","Physics","Pediatrics","Michigan Engineering","Medicine","Mathematics","Life Science","Lecture","Information and Technology","Applications","Biology","Biomedical Engineering","Biosciences","Cardiovascular","Chemistry","Discussion","Education","Electrical Engineering and Computer Science","Engineering","Free","Graduate Students","Human Genetics","Learning Health Systems"], "website":"https:\/\/medicine.umich.edu\/dept\/computational-medicine-bioinformatics\/events", "sponsors":[ { "group_name":"DCMB Seminar Series", "group_id":"3754", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2023\/10\/event_114673_original-1.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2023\/10\/event_114673_original-1.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2023\/10\/event_114673_original-1.jpeg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2023\/10\/event_114673_original-1.jpeg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2023\/10\/event_114673_original-1.jpeg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2023\/10\/event_114673_original-1.jpeg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2023\/10\/event_114673_original-1.jpeg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2023\/10\/event_114673_original-1.jpeg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2023\/10\/event_114673_original-1.jpeg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2023\/10\/event_114673_original-1.jpeg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2023\/10\/event_114673_original-1.jpeg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2023\/10\/event_114673_original-1.jpeg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2023\/10\/event_114673_original-1.jpeg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2023\/10\/event_114673_original-1.jpeg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2023\/10\/event_114673_original-1.jpeg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2023\/10\/event_114673_original-1.jpeg" }, "occurrence_count":1, "first_occurrence":21833285 } , "114711-21833346": { "datetime_modified":"20231221T123059", "datetime_start":"20231206T163000", "datetime_end":"20231206T171500", "has_end_time":1, "date_start":"2023-12-06", "date_end":"2023-12-06", "time_start":"16:30:00", "time_end":"17:15:00", "time_zone":"America\/Detroit", "event_title":"Create Classroom Impact & Advance Your Career with City Year", "occurrence_title":"", "combined_title":"Create Classroom Impact & Advance Your Career with City Year", "event_subtitle":"", "event_type":"Careers \/ Jobs", "event_type_id":"2", "description":"Discover if a year of service in the classroom supporting student growth is right for you. Join this 45-minute-long virtual info sessionand Q&A with a currently serving AmeriCorps Member to learn about City Year and the transferable skills you will gain working with us.", "occurrence_notes":null, "guid":"114711-21833346@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/114711", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"", "has_livestream":0, "cost":"", "tags":[], "website":"", "sponsors":[ { "group_name":"University Career Center UCC", "group_id":"1140", "website":"http:\/\/careercenter.umich.edu" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21833346 } , "115325-21834428": { "datetime_modified":"20231116T132803", "datetime_start":"20231206T163000", "datetime_end":"20231206T183000", "has_end_time":1, "date_start":"2023-12-06", "date_end":"2023-12-06", "time_start":"16:30:00", "time_end":"18:30:00", "time_zone":"America\/Detroit", "event_title":"Trade Show | Get Outside! Be Well!", "occurrence_title":"", "combined_title":"Trade Show | Get Outside! Be Well!: Student-generated products that encourage your well being!", "event_subtitle":"Student-generated products that encourage your well being!", "event_type":"Exhibition", "event_type_id":"7", "description":"University of Michigan's Art & Design, Business, Engineering, and School of Information students are gearing up for the Integrated Product Development (IPD) Trade Show! Members of our community will gather to view and make purchase decisions from the \"best of the best\" of their work over the past semester in this interdisciplinary course.\r\n\r\nIPD is an experiential, cross-disciplinary course that puts teams of students from Art & Design, Business, Engineering, and Information in a competitive product development environment. This innovative course has been featured on CNN and written in the New York Times, Wall Street Journal, and Businessweek. The course is hosted by the Tauber Institute for Global Operations and is taught jointly by faculty members Sheldon Davis of the Stephen M. Ross School of Business and Stephanie Tharp from the Penny W. Stamps School of Art & Design.\r\n\r\nThe Problem Statement: to design a tangible outdoor wellness product that empowers adults over 40 to engage with nature, improve their physical and\/or mental well-being, and foster a habit of outdoor activities.\r\n\r\nSee the actual products and test them out. Then cast your vote! Network, have fun, and meet up with friends, old and new!\r\n\r\nParking is via street meter, or public parking is available in the Hill Street Structure Parking Garage.\r\n\r\nThe event is free and open to the public.\r\n\r\nGREAT LOCATION: The \"Winter Garden\", first floor of the Ross School of Business, 701 Tappan, Ann Arbor, MI", "occurrence_notes":"First floor of the Ross School of Business", "guid":"115325-21834428@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/115325", "building_id":"1005188", "building_name":"Ross School of Business", "campus_maps_id":"547", "room":"The Winter Garden", "location_name":"Ross School of Business", "has_livestream":0, "cost":"", "tags":["Art","Business","Engineering","Fitness","Information and Technology","Mindfulness","Outdoors","Well-being"], "website":"https:\/\/tauber.umich.edu\/news-events\/events\/ipd-trade-show-get-outside-be-well", "sponsors":[ { "group_name":"Tauber Institute for Global Operations", "group_id":"3409", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2023\/11\/event_115325_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2023\/11\/event_115325_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2023\/11\/event_115325_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2023\/11\/event_115325_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2023\/11\/event_115325_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2023\/11\/event_115325_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2023\/11\/event_115325_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2023\/11\/event_115325_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2023\/11\/event_115325_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2023\/11\/event_115325_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2023\/11\/event_115325_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2023\/11\/event_115325_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2023\/11\/event_115325_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2023\/11\/event_115325_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2023\/11\/event_115325_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2023\/11\/event_115325_original-1.png" }, "occurrence_count":1, "first_occurrence":21834428 } }