{ "133290-21872697": { "datetime_modified":"20250228T094314", "datetime_start":"20250402T160000", "datetime_end":"20250402T170000", "has_end_time":1, "date_start":"2025-04-02", "date_end":"2025-04-02", "time_start":"16:00:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"DCMB Weekly Seminar featuring Vicky Yao, PhD (of Rice University)", "occurrence_title":"", "combined_title":"DCMB Weekly Seminar featuring Vicky Yao, PhD (of Rice University): \"Integrative computational approaches for modeling complex disease biology across scales and systems\"", "event_subtitle":"\"Integrative computational approaches for modeling complex disease biology across scales and systems\"", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"Abstract: To effectively model the molecular underpinnings of complex traits and diseases, computational methods must integrate diverse data types, handle partial or limited observations, and remain robust to variations in dataset size. In this talk, I will present several recent methods developed to address these challenges across diverse studies, assay types, and organisms, leveraging novel statistical and machine learning approaches. First, I will introduce ALPINE, an NMF-based framework that disentangles the influence of technical and non-relevant phenotypic factors in single-cell transcriptomic data, enabling the integration of multiple studies. Integrating across data types, I will discuss our method, seismic, which combines genome-wide association studies with single-cell RNA sequencing to prioritize disease-relevant cell types, linking genetic variation to cellular function. Finally, I will discuss ETNA, a machine translation-inspired approach that embeds protein-protein interaction networks from different organisms into a shared space, facilitating cross-species functional comparisons. 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This workshop will be presented by the International Center and the Language Resource Center. \r\n\r\nDinner will be provided!\r\n\r\nThis session is part of the International Center\u2019s Global Wolverines: Preparing You to Have a Successful International Experience event series.", "occurrence_notes":null, "guid":"134307-21874152@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/134307", "building_id":"1005177", "building_name":"North Quad", "campus_maps_id":"553", "room":"Language Resource Center (1500 North Quad)", "location_name":"North Quad", "has_livestream":0, "cost":"", "tags":["International"], "website":"https:\/\/sessions.studentlife.umich.edu\/track\/event\/session\/91830", "sponsors":[ { "group_name":"International Center", "group_id":"1060", "website":"" }, { "group_name":"Language Resource Center", "group_id":"3209", "website":"http:\/\/lsa.umich.edu\/lrc" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2025\/03\/event_134307_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2025\/03\/event_134307_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2025\/03\/event_134307_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2025\/03\/event_134307_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2025\/03\/event_134307_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2025\/03\/event_134307_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2025\/03\/event_134307_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2025\/03\/event_134307_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2025\/03\/event_134307_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2025\/03\/event_134307_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2025\/03\/event_134307_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2025\/03\/event_134307_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2025\/03\/event_134307_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2025\/03\/event_134307_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2025\/03\/event_134307_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2025\/03\/event_134307_original-1.png" }, "occurrence_count":1, "first_occurrence":21874152 } , "133827-21873602": { "datetime_modified":"20250313T120810", "datetime_start":"20250402T160000", "datetime_end":"20250402T170000", "has_end_time":1, "date_start":"2025-04-02", "date_end":"2025-04-02", "time_start":"16:00:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"National Security in the 2020s: Looking Back and Ahead", "occurrence_title":"", "combined_title":"National Security in the 2020s: Looking Back and Ahead: Washington Post Journalist John Hudson in conversation with Associate Professor of Practice Javed Ali", "event_subtitle":"Washington Post Journalist John Hudson in conversation with Associate Professor of Practice Javed Ali", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"This event will explore national security and foreign policy in the 2020s, focusing on the key issues and challenges faced during both the Biden and Trump administrations. Moderated by Javed Ali, Associate Professor of Practice at the Gerald R. Ford School of Public Policy, the fireside chat will provide valuable insights into the evolving landscape of global security. The discussion will offer a comprehensive look at how these administrations have shaped U.S. foreign policy. It\u2019s a great opportunity to engage with critical topics that are impacting national security today.\r\n\r\nFrom the Speaker's Bio:\r\n\r\nJohn Hudson is a reporter at The Washington Post covering the State Department and national security. He was part of the team that was a finalist for the Pulitzer Prize for Public Service for coverage of the murder of journalist Jamal Khashoggi. He has reported from dozens of countries, including Ukraine, China, Afghanistan, India, Georgia, Belarus, Pakistan, Malaysia, Ethiopia, Vietnam, Colombia, Costa Rica, France, Kenya, Nigeria and many more. In 2022 and 2023, he covered the war in Ukraine. In 2008, he covered the war in Georgia. He appears frequently on MSNBC and CNN. Hudson holds a B.A. in International Relations from Michigan State University.\r\n\r\nJaved Ali is an associate professor of practice at the Gerald R. Ford School of Public Policy, he joined the Weiser Diplomacy Center in 2021. Ali brings more than 20 years of professional experience in national security and intelligence issues in Washington, DC. He held positions in the Defense Intelligence Agency and the Department of Homeland Security before joining the Federal Bureau of Investigation. While at the FBI, he also held senior roles on joint duty assignments at the National Intelligence Council, the National Counterterrorism Center, and the National Security Council under the Trump Administration. 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