{ "116406-21836731": { "datetime_modified":"20240126T122105", "datetime_start":"20240403T153000", "datetime_end":"20240403T163000", "has_end_time":1, "date_start":"2024-04-03", "date_end":"2024-04-03", "time_start":"15:30:00", "time_end":"16:30:00", "time_zone":"America\/Detroit", "event_title":"MIPSE Seminar | To Ignition and Beyond", "occurrence_title":"", "combined_title":"MIPSE Seminar | To Ignition and Beyond: Dr. Denise Hinkel, Lawrence Livermore National Laboratory", "event_subtitle":"Dr. Denise Hinkel, Lawrence Livermore National Laboratory", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"Abstract: \r\nThe National Ignition Facility (NIF) at Lawrence Livermore National Laboratory is the world\u2019s most energetic laser now capable of providing 2.2 MJ of laser light at 351 nm to the target chamber. The primary goal of NIF is to demonstrate fusion ignition (and then as high-as-possible yield), an un-precedented proof-of-principle. On August 8, 2021, fusion ignition was demonstrated at NIF according to several ignition metrics. This was achieved using the indirectly driven laser fusion concept, where laser light is converted to x-rays upon striking the interior of a high-Z cavity, creating a radiation oven for a capsule comprised of heavy hydrogen fuel (which when driven to appropriate conditions undergoes fusion) surrounded by an ablator. The experiment, N210808, burned about 2% of the fuel, using 1.9 MJ of laser energy and producing 1.37 MJ of fusion yield. Repeat experiments showed variability to unintentional degradations such as capsule quality and low mode asymmetries, and so, to enhance robustness, a larger capsule was fielded, using 7% more laser energy, i.e., 2.05 MJ. This experiment (N221204), and its repeat (N230729), achieved 3.15 and 3.88 MJ of fusion yield, or a target gain of 1.5 -1.9, burning up to 5% of the fuel.\r\n This presentation reviews background material and guiding principles, as well as important lessons learned. Additionally, the challenges that lie ahead of the national inertial confinement fusion program will be outlined.\r\n\r\nAbout the Speaker: \r\nDr. Denise Hinkel is a physicist at Lawrence Livermore National Lab and serves as Modeling Lead for the Inertial Confinement Fusion (ICF) Program as well as Associate Division Leader for ICF and High Energy Density Physics (HED) in the Design Physics Division. She is also technical coordinator of a special program. Denise\u2019s expertise spans theoretical analyses to massively parallel computing, basic plasma physics to reduced model descriptions and design and analysis of laser-based experiments using radiation-hydrodynamics simulations. She applied her design expertise to a series of NIF shots known as the \u201cHigh Foot\u201d, where for the first time the energy released in fusion reactions exceeded the energy used to compress the fuel. Denise has served as the point-of-contact for Laboratory Directed Research and Development, managing the portfolio and developing strategic plans with her directorate and institution. Denise received the MS and PhD in Physics from UCLA and became Fellow of the American Physical Society (APS) in 2007. In 2022, she served as Chair of the APS Division of Plasma Physics. She has received multiple awards, has provided physics outreach to students of all ages, and has served on many review committees.\r\n\r\nThis is a hybrid event. For Zoom link, please see MIPSE website:\r\nhttps:\/\/mipse.umich.edu\/seminars_2324.php#winter2024", "occurrence_notes":null, "guid":"116406-21836731@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/116406", "building_id":"1000448", "building_name":"Electrical Engineering and Computer Science Building", "campus_maps_id":"56", "room":"1005", "location_name":"Electrical Engineering and Computer Science Building", "has_livestream":0, "cost":"", "tags":["Engineering","Michigan Engineering","Physics","Plasma","Research","seminar","Talk"], "website":"https:\/\/mipse.umich.edu\/seminars_2324.php", "sponsors":[ { "group_name":"Michigan Institute for Plasma Science and Engineering (MIPSE)", "group_id":"4073", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2023\/12\/event_116406_original-1.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2023\/12\/event_116406_original-1.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2023\/12\/event_116406_original-1.jpeg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2023\/12\/event_116406_original-1.jpeg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2023\/12\/event_116406_original-1.jpeg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2023\/12\/event_116406_original-1.jpeg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2023\/12\/event_116406_original-1.jpeg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2023\/12\/event_116406_original-1.jpeg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2023\/12\/event_116406_original-1.jpeg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2023\/12\/event_116406_original-1.jpeg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2023\/12\/event_116406_original-1.jpeg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2023\/12\/event_116406_original-1.jpeg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2023\/12\/event_116406_original-1.jpeg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2023\/12\/event_116406_original-1.jpeg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2023\/12\/event_116406_original-1.jpeg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2023\/12\/event_116406_original-1.jpeg" }, "occurrence_count":1, "first_occurrence":21836731 } , "120915-21845543": { "datetime_modified":"20240418T123153", "datetime_start":"20240403T153000", "datetime_end":"20240403T161500", "has_end_time":1, "date_start":"2024-04-03", "date_end":"2024-04-03", "time_start":"15:30:00", "time_end":"16:15:00", "time_zone":"America\/Detroit", "event_title":"Pathways Into Teaching-Marshall Teacher Residency", "occurrence_title":"", "combined_title":"Pathways Into Teaching-Marshall Teacher Residency", "event_subtitle":"", "event_type":"Careers \/ Jobs", "event_type_id":"2", "description":"The Pathways Into Teaching workshop is an overview of the various pathways into teaching, including Master's programs, Intern Programsand Teacher Residencies. This workshop is perfect for anyone considering a career in education and will be facilitated by representative from the Marshall Teacher Residency Program.", "occurrence_notes":null, "guid":"120915-21845543@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/120915", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"", "has_livestream":0, "cost":"", "tags":[], "website":"", "sponsors":[ { "group_name":"University Career Center UCC", "group_id":"1140", "website":"http:\/\/careercenter.umich.edu" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21845543 } , "116006-21836059": { "datetime_modified":"20240329T142000", "datetime_start":"20240403T160000", "datetime_end":"20240403T173000", "has_end_time":1, "date_start":"2024-04-03", "date_end":"2024-04-03", "time_start":"16:00:00", "time_end":"17:30:00", "time_zone":"America\/Detroit", "event_title":"Algebraic Geometry Seminar: Hom schemes for algebraic groups", "occurrence_title":"", "combined_title":"Algebraic Geometry Seminar: Hom schemes for algebraic groups: Sean Cotner (U. Michigan)", "event_subtitle":"Sean Cotner (U. Michigan)", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Grothendieck showed that morphisms of projective varieties are parameterized by a scheme. This fails tremendously for affine varieties. However, group structures tend to be rigidifying, and indeed homomorphisms of affine groups are sometimes also parameterized by a scheme. In this talk, I will discuss the general problem of parameterizing homomorphisms of algebraic groups, both over a field (at first) and over a general base (by the end). Over a field, the main result has a surprisingly elementary proof, which we will describe. We will also give several examples throughout which illustrate strange phenomena that crop up.", "occurrence_notes":null, "guid":"116006-21836059@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/116006", "building_id":"1000166", "building_name":"East Hall", "campus_maps_id":"53", "room":"4096", "location_name":"East Hall", "has_livestream":0, "cost":"", "tags":["Mathematics"], "website":"", "sponsors":[ { "group_name":"Algebraic Geometry Seminar - Department of Mathematics", "group_id":"4880", "website":"" }, { "group_name":"Department of Mathematics", "group_id":"3791", "website":"" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21836059 } , "119341-21842589": { "datetime_modified":"20240226T094521", "datetime_start":"20240403T160000", "datetime_end":"20240403T170000", "has_end_time":1, "date_start":"2024-04-03", "date_end":"2024-04-03", "time_start":"16:00:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"DCMB \/ CCMB Weekly Seminar featuring Christina Leslie, PhD (of Memorial Sloan Kettering Cancer Center)", "occurrence_title":"", "combined_title":"DCMB \/ CCMB Weekly Seminar featuring Christina Leslie, PhD (of Memorial Sloan Kettering Cancer Center): Advances in predictive models for single-cell and regulatory genomics", "event_subtitle":"Advances in predictive models for single-cell and regulatory genomics", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"Abstract:\r\n\r\nThe last several years have brought notable successes in the application of machine learning approaches, and especially deep learning models, to problems in single-cell and regulatory genomics. The advent of single-cell chromatin accessibility (scATAC-seq) and multiome (scRNA+ATAC-seq) brings new machine learning challenges and opportunities to link chromatin state to developmental trajectories, gene regulation, and even higher order chromatin organization. We will present recent models from our group to exploit these new single-cell data modalities: CellSpace, a sequence-informed embedding algorithm for scATAC-seq that learns biologically meaningful latent structure while mitigating batch effects; SCARlink, a gene-level regression model for multiome data that identifies cell-type-specific enhancers and enables interpretation of disease-associated genetic variants; and ChromaFold, a deep learning model that predicts the 3D contact map from scATAC-seq alone.\r\n\r\nhttps:\/\/umich-health.zoom.us\/j\/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09", "occurrence_notes":null, "guid":"119341-21842589@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/119341", "building_id":"1005047", "building_name":"Palmer Commons", "campus_maps_id":"188", "room":"Forum Hall and NCRC #520, Room 1122", "location_name":"Palmer Commons", "has_livestream":0, "cost":"", "tags":["Learning Health Systems","Talk","Structural Biology","seminar","Science","Research","Public Health","Precision Health","Physics","Pediatrics","Michigan Engineering","Medicine","Mathematics","Life Science","Lecture","Applications","Information and Technology","Human Genetics","Graduate Students","Free","Engineering","Electrical Engineering and Computer Science","Education","Discussion","Chemistry","Cardiovascular","Biosciences","Biomedical Engineering","Biology","Basic Science"], "website":"https:\/\/medicine.umich.edu\/dept\/computational-medicine-bioinformatics\/events\/202404\/ccmb-seminar-christina-leslie-phd", "sponsors":[ { "group_name":"DCMB Seminar Series", "group_id":"3754", "website":"" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21842589 } }