{ "120052-21843991": { "datetime_modified":"20240328T163210", "datetime_start":"20240412T100000", "datetime_end":"20240412T110000", "has_end_time":1, "date_start":"2024-04-12", "date_end":"2024-04-12", "time_start":"10:00:00", "time_end":"11:00:00", "time_zone":"America\/Detroit", "event_title":"Michael Woodroofe Lecture Series: Kathryn Roeder, UPMC Professor of Statistics and Life Sciences, Statistics & Data Science Dietrich College of Humanities and Social Sciences, Carnegie Mellon University", "occurrence_title":"", "combined_title":"Michael Woodroofe Lecture Series: Kathryn Roeder, UPMC Professor of Statistics and Life Sciences, Statistics & Data Science Dietrich College of Humanities and Social Sciences, Carnegie Mellon University: \u201cTesting for differential expression in single-cell data with unmeasured confounders\u201d", "event_subtitle":"\u201cTesting for differential expression in single-cell data with unmeasured confounders\u201d", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"When aiming to identify differentially expressed genes, thousands of simultaneous hypothesis tests are performed, which could be biased by the presence of unmeasured confounders. In the context of linear models, surrogate variable models and related approaches have been developed to control for the effect of confounding factors with considerable success. However, in recent years, differential expression testing has been dramatically expanded to include a variety of genomic readouts for which the linear model rarely holds. A Poisson, negative binomial or Bernoulli model is likely more appropriate. Inspired by this advancement we develop a solution for multivariate generalized linear models in the presence of arbitrary confounding effects. We establish consistency and asymptotic normality of our proposed test statistic. Numerical experiments demonstrate that the proposed method controls the false discovery rate and is more powerful than alternative methods. By comparing single-cell RNA- seq counts from Lupus and control samples, we demonstrate the suitability of adjusting confounding effects when significant covariates are absent from the model. If time permits we will explore how proximal causing learning methods could provide an alternative approach for removing the effects of unmeasured confounders.", "occurrence_notes":null, "guid":"120052-21843991@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/120052", "building_id":"1000167", "building_name":"West Hall", "campus_maps_id":"163", "room":"340", "location_name":"West Hall", "has_livestream":0, "cost":"", "tags":["seminar"], "website":"https:\/\/lsa.umich.edu\/stats", "sponsors":[ { "group_name":"Department of Statistics", "group_id":"3473", "website":"" }, { "group_name":"Department of Statistics Seminar Series", "group_id":"3585", "website":"" }, { "group_name":"Michael Woodroofe Lecture Series", "group_id":"3869", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2024\/03\/event_120052_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2024\/03\/event_120052_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2024\/03\/event_120052_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2024\/03\/event_120052_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2024\/03\/event_120052_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2024\/03\/event_120052_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2024\/03\/event_120052_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2024\/03\/event_120052_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2024\/03\/event_120052_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2024\/03\/event_120052_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2024\/03\/event_120052_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2024\/03\/event_120052_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2024\/03\/event_120052_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2024\/03\/event_120052_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2024\/03\/event_120052_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2024\/03\/event_120052_original-1.png" }, "occurrence_count":1, "first_occurrence":21843991 } , "119221-21842434": { "datetime_modified":"20240221T155241", "datetime_start":"20240412T100000", "datetime_end":"20240412T160000", "has_end_time":1, "date_start":"2024-04-12", "date_end":"2024-04-12", "time_start":"10:00:00", "time_end":"16:00:00", "time_zone":"America\/Detroit", "event_title":"Products from Pollution: Carbon Capture and Conversion", "occurrence_title":"", "combined_title":"Products from Pollution: Carbon Capture and Conversion: Adding value while fighting climate change", "event_subtitle":"Adding value while fighting climate change", "event_type":"Exhibition", "event_type_id":"7", "description":"Phasing out fossil fuels is a primary means to fight climate change, but it alone is not enough. Even if all emissions ceased tomorrow, atmospheric CO2 levels are already dangerously high and the climate would keep warming before it eventually stabilizes. We have to reduce or \u201ccapture\u201d legacy CO2 to avert disaster. As the International Panel on Climate Change stated, the *only* way we can meet our climate goal is to use carbon capture in our climate change fighting tool kit. \r\n\r\nMany of the products that we use every day are made with carbon. Treating legacy CO2 as a resource with economic value rather than a pollutant allows us to generate revenue while also fighting climate change. \r\n\r\nHowever, not all uses or types of captured CO2 are equal in terms of environmental or economic benefits. This exhibit includes a video game that helps explain the pros and cons associated with different methods and applications of carbon capture. \r\n\r\nAdditionally, it also provides examples of two types of carbon removal, an interactive block activity, and sample products made from captured CO2.", "occurrence_notes":null, "guid":"119221-21842434@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/119221", "building_id":"0", "building_name":"Matthaei Botanical Gardens", "campus_maps_id":"554", "room":"", "location_name":"Matthaei Botanical Gardens", "has_livestream":0, "cost":"", "tags":["climate","Sustainability","Environment","Engineering","Climate Change","carbon reduction"], "website":"", "sponsors":[ { "group_name":"Global CO2 Initiative", "group_id":"5002", "website":"https:\/\/www.globalco2initiative.org\/" }, { "group_name":"Matthaei Botanical Gardens & Nichols Arboretum", "group_id":"1072", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2024\/02\/event_119221_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2024\/02\/event_119221_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2024\/02\/event_119221_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2024\/02\/event_119221_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2024\/02\/event_119221_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2024\/02\/event_119221_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2024\/02\/event_119221_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2024\/02\/event_119221_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2024\/02\/event_119221_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2024\/02\/event_119221_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2024\/02\/event_119221_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2024\/02\/event_119221_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2024\/02\/event_119221_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2024\/02\/event_119221_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2024\/02\/event_119221_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2024\/02\/event_119221_original-1.png" }, "occurrence_count":44, "first_occurrence":21842393 } , "121141-21845879": { "datetime_modified":"20240404T110149", "datetime_start":"20240412T100000", "datetime_end":"20240412T190000", "has_end_time":1, "date_start":"2024-04-12", "date_end":"2024-04-12", "time_start":"10:00:00", "time_end":"19:00:00", "time_zone":"America\/Detroit", "event_title":"Reframing Our Language Experience (ROLE) Collective Symposium", "occurrence_title":"", "combined_title":"Reframing Our Language Experience (ROLE) Collective Symposium: Rejecting Harmful Native Speaker\/Signer Ideologies", "event_subtitle":"Rejecting Harmful Native Speaker\/Signer Ideologies", "event_type":"Conference \/ Symposium", "event_type_id":"5", "description":"The Reframing Our Language Experience (ROLE) Collective was co-founded by Dr. Savithry Namboodiripad (U-M Linguistics) and Dr. Ethan Kutlu (University of Iowa). Currently, the collective has over 50 scholars. \r\n\r\nThe 1st ROLE Collective Symposium will take place this year online on April 12th (keynotes and short talks) and April 19th (workshop). The theme of this symposium is \u201cRejecting Harmful Native Speaker\/Signer Ideologies.\u201d\r\n\r\nStructure of the Symposium\r\nThe one-week difference between Day 1 and Day 2 is to ensure that any attendees who may not have been able to attend some or all of the talks on Day 1 will have enough time to watch the videos and be prepared for the second day. In addition, though all of the short talks will be uploaded online only, and not broadcast synchronously on Day 1, there will be a synchronous discussion of these talks on Day 2.\r\n\r\nDay 2 will begin with a structured discussion of the short talks. Then, participants will split up into at least 5 themed breakout rooms to work together to discuss how to address harmful notions of language in various contexts. These contexts include research practices (e.g., how to ethically and accurately capture differences in language experience, how to implement conceptual changes via novel statistical methods, how to recruit participants without relying on the native speaker\/signer construct), clinical assessments (e.g., creating resources about how language ideologies can lead to misdiagnoses of individuals whose language practices are marginalized, and advocating for the further development of assessment materials which are inclusive of a broader range of language\/varieties), admissions processes (e.g., creating white papers for graduate and undergraduate programs to eschew native speaker\/signer ideologies in assessments of the language of incoming students), evaluation of academic language (e.g., creating guidelines for editors and reviewers to assess the language of submitted manuscript\/grant application without relying on the native speaker construct), communicating with the public (e.g., creating public-facing information for the affirmation of all kinds of language experience), and whatever other priorities are identified by participants \u2013 participants\u2019 priorities will be identified via a survey distributed after the first symposium day and before the workshop day.", "occurrence_notes":null, "guid":"121141-21845879@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/121141", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Virtual", "has_livestream":0, "cost":"", "tags":["Language Policy"], "website":"https:\/\/uiowa.zoom.us\/meeting\/register\/tJAkdO6orTouHNUhOKAhD6MCXGLFIC9s9kDW#\/registration", "sponsors":[ { "group_name":"Department of Linguistics", "group_id":"3480", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2024\/04\/event_121141_original-1.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2024\/04\/event_121141_original-1.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2024\/04\/event_121141_original-1.jpeg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2024\/04\/event_121141_original-1.jpeg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2024\/04\/event_121141_original-1.jpeg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2024\/04\/event_121141_original-1.jpeg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2024\/04\/event_121141_original-1.jpeg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2024\/04\/event_121141_original-1.jpeg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2024\/04\/event_121141_original-1.jpeg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2024\/04\/event_121141_original-1.jpeg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2024\/04\/event_121141_original-1.jpeg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2024\/04\/event_121141_original-1.jpeg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2024\/04\/event_121141_original-1.jpeg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2024\/04\/event_121141_original-1.jpeg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2024\/04\/event_121141_original-1.jpeg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2024\/04\/event_121141_original-1.jpeg" }, "occurrence_count":2, "first_occurrence":21845879 } , "120362-21844614": { "datetime_modified":"20240412T092027", "datetime_start":"20240412T100000", "datetime_end":"20240412T110000", "has_end_time":1, "date_start":"2024-04-12", "date_end":"2024-04-12", "time_start":"10:00:00", "time_end":"11:00:00", "time_zone":"America\/Detroit", "event_title":"Semester abroad at Vrije Universiteit Amsterdam (VU) in Amsterdam, Netherlands", "occurrence_title":"", "combined_title":"Semester abroad at Vrije Universiteit Amsterdam (VU) in Amsterdam, Netherlands", "event_subtitle":"", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Learn all about the VU program in Amsterdam, what is has to offer and the best academic opportunites.\u00a0", "occurrence_notes":null, "guid":"120362-21844614@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/120362", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"Virtual", "has_livestream":0, "cost":"", "tags":["Sessions"], "website":"https:\/\/sessions.studentlife.umich.edu\/p\/track\/11390", "sponsors":[ { "group_name":"Sessions @ Michigan", "group_id":"4791", "website":"https:\/\/sessions.studentlife.umich.edu\/" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21844614 } }