{ "146965-21899887": { "datetime_modified":"20260325T140233", "datetime_start":"20260528T160000", "datetime_end":"20260528T171500", "has_end_time":1, "date_start":"2026-05-28", "date_end":"2026-05-28", "time_start":"16:00:00", "time_end":"17:15:00", "time_zone":"America\/Detroit", "event_title":"Co-Fractionation \u2018Multi-omics\u2019 Mass Spectrometry for Lipid-Protein Interactome Analysis", "occurrence_title":"", "combined_title":"Co-Fractionation \u2018Multi-omics\u2019 Mass Spectrometry for Lipid-Protein Interactome Analysis: Gavin Reid (University of Melbourne)", "event_subtitle":"Gavin Reid (University of Melbourne)", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Lipids play essential roles in regulating various biological processes through functional interactions with integral or peripherally associated proteins and protein complexes. While mass spectrometry (MS)-based strategies have enabled global lipidome and proteome identification and quantitative profiling, high-throughput strategies to investigate the lipid-protein \u2018interactome\u2019 at the systems level are currently lacking. Here, I will first describe the development of advanced \u2018shotgun\u2019 lipidomics data acquisition workflows, including the use of ion-mobility for selective enrichment of low abundance lipid classes, and UV-photodissociation MS\/MS to enable complete lipid structural characterisation [e.g., Anal. Chem. 2024, 96, 12296-12307.; Anal. Bioanal. Chem. 2020, 412, 2339\u20132351.], and their application to characterise a novel cause of autosomal regressive multisystem mitochondrial disease resulting from deleterious variants in cardiolipin synthase 1 (CRLS1) [Human Mol. Genetics. 2022, 31, 3597-3612.]. Next, using an integrated \u2018multi-omics\u2019 workflow for comprehensive lipidome and proteome profiling, I will report that the knockout of non-mitochondrial genes in peroxisome, endoplasmic reticulum (ER) and Golgi organelles also results in mitochondrial dysfunction, caused by unexpected alterations in ether-glycerophospholipid metabolic pathways [Nature. Cell Biol. 2024, 26, 57-71]. Finally, to investigate the lipid\u2013protein interaction relationships in these systems, a novel Co-Fractionation Multi-Omics Mass Spectrometry (CF-MOMS) strategy will be described to characterise global alterations in the lipid-protein \u2018interactome interactomes in WT and CRLS1KO cell lines, and to highlight the functional involvement of cardiolipin-protein interactions in maintaining the assembly\/stability and activity of mitochondrial membrane proteins.", "occurrence_notes":null, "guid":"146965-21899887@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/146965", "building_id":"1000158", "building_name":"Chemistry Dow Lab", "campus_maps_id":"34", "room":"1640", "location_name":"Chemistry Dow Lab", "has_livestream":0, "cost":"", "tags":["Chemistry","Analytical Chemistry"], "website":"https:\/\/findanexpert.unimelb.edu.au\/profile\/28892-gavin-reid", "sponsors":[ { "group_name":"Department of Chemistry", "group_id":"3761", "website":"https:\/\/lsa.umich.edu\/chem" }, { "group_name":"Analytical Chemistry", "group_id":"4384", "website":"" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21899887 } , "148451-21904292": { "datetime_modified":"20260528T120013", "datetime_start":"20260528T170000", "datetime_end":"20260528T183000", "has_end_time":1, "date_start":"2026-05-28", "date_end":"2026-05-28", "time_start":"17:00:00", "time_end":"18:30:00", "time_zone":"America\/Detroit", "event_title":"ADHD Student - Visit the Peony Garden at the Arb!", "occurrence_title":"", "combined_title":"ADHD Student - Visit the Peony Garden at the Arb!", "event_subtitle":"", "event_type":"Social \/ Informal Gathering", "event_type_id":"19", "description":"Join the ADHD Student Group at the Arb to enjoy the blooms and a short walk! Art supplies will be available if you'd like to draw or paint the flowers. Please reach out to Lily Walker at lilywalk@umich.edu with any questions. Hope to see you there!!\r\nWhere:\u00a0Nichols Arboretum (1610 Washington Heights, Ann Arbor, MI 48104)\r\nWhen: Thursday May 28th from 5pm - 6:30pm\r\n*Note on parking: for folks commuting, parking near the gardens in lot M28 (1500 Washington Heights) is free after 5pm!", "occurrence_notes":null, "guid":"148451-21904292@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/148451", "building_id":"1000005", "building_name":"Nichols Arboretum", "campus_maps_id":"119", "room":"", "location_name":"Nichols Arboretum", "has_livestream":0, "cost":"", "tags":[], "website":"https:\/\/maizepages.umich.edu\/event\/12478020", "sponsors":[ { "group_name":"Maize Pages Student Organizations", "group_id":"2390", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/05\/event_148451_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2026\/05\/event_148451_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/05\/event_148451_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2026\/05\/event_148451_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2026\/05\/event_148451_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2026\/05\/event_148451_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2026\/05\/event_148451_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2026\/05\/event_148451_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2026\/05\/event_148451_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2026\/05\/event_148451_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2026\/05\/event_148451_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2026\/05\/event_148451_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2026\/05\/event_148451_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2026\/05\/event_148451_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2026\/05\/event_148451_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2026\/05\/event_148451_original-1.png" }, "occurrence_count":1, "first_occurrence":21904292 } , "147886-21902314": { "datetime_modified":"20260506T165253", "datetime_start":"20260528T170000", "datetime_end":"20260528T183000", "has_end_time":1, "date_start":"2026-05-28", "date_end":"2026-05-28", "time_start":"17:00:00", "time_end":"18:30:00", "time_zone":"America\/Detroit", "event_title":"Virtual Pre-Law Information Sessions", "occurrence_title":"", "combined_title":"Virtual Pre-Law Information Sessions: For students who have been admitted", "event_subtitle":"For students who have been admitted", "event_type":"Livestream \/ Virtual", "event_type_id":"24", "description":"The Pre-Law Primer Sessions are designed for incoming students interested in exploring the pre-law path at U-M. We recommend that students attend their scheduled Virtual Academic Advising Session before attending a Pre-Law Primer Session.", "occurrence_notes":null, "guid":"147886-21902314@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/147886", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"Virtual", "has_livestream":1, "livestream_type":"zoom", "livetream_require_login":0, "livestream_id":"92257209762", "livestream_link":"https:\/\/umich.zoom.us\/j\/92257209762", "cost":"", "tags":["Pre Law","Newnan Lsa Pre-law","Newnan Lsa Academic Advising Center","Newnan Academic Advising","Newnan","Advising"], "website":"", "sponsors":[ { "group_name":"Newnan LSA Pre-Law", "group_id":"4048", "website":"" }, { "group_name":"Newnan LSA Academic Advising Center", "group_id":"3721", "website":"" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":10, "first_occurrence":21902314 } , "142827-21891719": { "datetime_modified":"20260225T101055", "datetime_start":"20260528T200000", "datetime_end":"", "has_end_time":0, "date_start":"2026-05-28", "date_end":"", "time_start":"20:00:00", "time_end":"", "time_zone":"America\/Detroit", "event_title":"Dave & Kristi", "occurrence_title":"", "combined_title":"Dave & Kristi: Presented by The Ark", "event_subtitle":"Presented by The Ark", "event_type":"Performance", "event_type_id":"15", "description":"\u201cIrrepressible verve and joy.\u201d \u2013Daniel Bracken, Wheatland Music Festival\n\nOne time garage rock troubadour Dave Boutette, and former Radio City Rockette Kristi Lynn Davis make what could be considered an unexpected musical pairing, but they have certainly found a way to make it work. Since pairing Dave\u2019s celebrated songwriting with Kristi\u2019s natural gift for harmony, the duo has delighted audiences at music festivals, house concerts, and listening rooms from Michigan\u2019s Upper Peninsula to the Maryland shore. Their most recent release THE CHICKADEES reached #11 on the Folk DJ Chart in June of 2025.\n\nFor additional spark in the set list that night, Dave & Kristi will be bringing along Jason Dennie on mandolin and Brad Phillips on fiddle.\n\nDave & Kristi\u2019s songs mix many schools of American roots and popular music including folk, blues, swing, and old time country. The lyrics testify to the power of true love, rebirth, Polka bands, coffee, and migrating fish.", "occurrence_notes":null, "guid":"142827-21891719@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/142827", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"ARK Reserved", "has_livestream":0, "cost":"See Site For Pricing Information", "tags":["Ark","Mutotix"], "website":"https:\/\/mutotix.umich.edu\/6256\/6257", "sponsors":[ { "group_name":"Michigan Union Ticket Office (MUTO)", "group_id":"1053", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2025\/12\/event_142827_original-1.jpg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2025\/12\/event_142827_original-1.jpg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2025\/12\/event_142827_original-1.jpg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2025\/12\/event_142827_original-1.jpg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2025\/12\/event_142827_original-1.jpg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2025\/12\/event_142827_original-1.jpg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2025\/12\/event_142827_original-1.jpg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2025\/12\/event_142827_original-1.jpg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2025\/12\/event_142827_original-1.jpg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2025\/12\/event_142827_original-1.jpg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2025\/12\/event_142827_original-1.jpg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2025\/12\/event_142827_original-1.jpg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2025\/12\/event_142827_original-1.jpg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2025\/12\/event_142827_original-1.jpg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2025\/12\/event_142827_original-1.jpg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2025\/12\/event_142827_original-1.jpg" }, "occurrence_count":1, "first_occurrence":21891719 } , "146151-21898509": { "datetime_modified":"20260303T152543", "datetime_start":"20260528T200000", "datetime_end":"20260528T230000", "has_end_time":1, "date_start":"2026-05-28", "date_end":"2026-05-28", "time_start":"20:00:00", "time_end":"23:00:00", "time_zone":"America\/Detroit", "event_title":"Echoes of the Past: Greektown as Seen by Sam Karres", "occurrence_title":"", "combined_title":"Echoes of the Past: Greektown as Seen by Sam Karres", "event_subtitle":"", "event_type":"Exhibition", "event_type_id":"7", "description":"Explore the personal sketchbooks of Sam Karres, Greek-American painter and artist, as he illustrates the daily life of residents in Greektown, Detroit. This exhibit highlights Detroit\u2019s Greek-American community and urban scenery during the late 20th century. Experience art and life through Sam\u2019s eyes with scenes of music, dance, restaurants, and the faces of the community. Let the vivid watercolor paintings and expressive sketches transport you to a Greektown of the past, and learn more about Sam Karres\u2019 life as an artist.\n\nFeaturing works from the Sam Karres Archive, 1955-2012, held by the University of Michigan Library's Special Collection Research Center. Curated by Annelie Zissis and Arthur Pfeifer-Rubey, Library Engagement Fellows.", "occurrence_notes":null, "guid":"146151-21898509@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/146151", "building_id":"1000181", "building_name":"Hatcher Graduate Library", "campus_maps_id":"65", "room":"Clark Library (2nd floor)", "location_name":"Hatcher Graduate Library", "has_livestream":0, "cost":"", "tags":["Library","Free"], "website":"https:\/\/www.lib.umich.edu\/events", "sponsors":[ { "group_name":"University Library", "group_id":"1186", "website":"https:\/\/www.facebook.com\/UMichLibrary\/" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/03\/event_146151_original-1.jpg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2026\/03\/event_146151_original-1.jpg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/03\/event_146151_original-1.jpg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2026\/03\/event_146151_original-1.jpg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2026\/03\/event_146151_original-1.jpg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2026\/03\/event_146151_original-1.jpg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2026\/03\/event_146151_original-1.jpg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2026\/03\/event_146151_original-1.jpg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2026\/03\/event_146151_original-1.jpg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2026\/03\/event_146151_original-1.jpg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2026\/03\/event_146151_original-1.jpg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2026\/03\/event_146151_original-1.jpg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2026\/03\/event_146151_original-1.jpg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2026\/03\/event_146151_original-1.jpg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2026\/03\/event_146151_original-1.jpg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2026\/03\/event_146151_original-1.jpg" }, "occurrence_count":141, "first_occurrence":21898454 } }