{ "152913-21914776": { "datetime_modified":"20261103T060210", "datetime_start":"20261103T093000", "datetime_end":"20261103T163000", "has_end_time":1, "date_start":"2026-11-03", "date_end":"2026-11-03", "time_start":"09:30:00", "time_end":"16:30:00", "time_zone":"America\/Detroit", "event_title":"Gift of Life Swab Week", "occurrence_title":"", "combined_title":"Gift of Life Swab Week", "event_subtitle":"", "event_type":"Community Service", "event_type_id":"4", "description":"Gift of Life is a national bone marrow and stem cell registry that connects patients battling blood cancers like leukemia and lymphoma with donors who can save their lives. Most patients don't have a match in their family, so they rely on strangers joining the registry. Our University of Michigan chapter has added over 2,700 Wolverines to the registry, leading to 18 confirmed matches and 3 life-saving transplants. This fall's Swab Week runs November 2 to 6 on the Diag, and this week we are going up against Ohio State in registrations. Joining takes about five minutes: fill out a quick form and swab your cheek. If you're between 18 and 35 and in good health, stop by, bring your friends, and you could be the match that gives someone a second chance at life. If your interested in volunteering please reach out we would love to have you help out. Go Blue!", "occurrence_notes":null, "guid":"152913-21914776@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/152913", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"The Diag", "has_livestream":0, "cost":"", "tags":[], "website":"https:\/\/maizepages.umich.edu\/event\/12820954", "sponsors":[ { "group_name":"Maize Pages Student Organizations", "group_id":"2390", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/11\/event_152913_original-141.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_thumb\/media\/attachments\/2026\/11\/event_152913_original-141.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large\/media\/attachments\/2026\/11\/event_152913_original-141.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2026\/11\/event_152913_original-141.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_lightbox\/media\/attachments\/2026\/11\/event_152913_original-141.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2026\/11\/event_152913_original-141.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2026\/11\/event_152913_original-141.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2026\/11\/event_152913_original-141.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large_lightbox\/media\/attachments\/2026\/11\/event_152913_original-141.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2026\/11\/event_152913_original-141.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2026\/11\/event_152913_original-141.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2026\/11\/event_152913_original-141.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid\/media\/attachments\/2026\/11\/event_152913_original-141.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2026\/11\/event_152913_original-141.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_large\/media\/attachments\/2026\/11\/event_152913_original-141.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_thumb\/media\/attachments\/2026\/11\/event_152913_original-141.png" }, "occurrence_count":1, "first_occurrence":21914776 } , "153438-21915858": { "datetime_modified":"20261103T063210", "datetime_start":"20261103T100000", "datetime_end":"20261103T110000", "has_end_time":1, "date_start":"2026-11-03", "date_end":"2026-11-03", "time_start":"10:00:00", "time_end":"11:00:00", "time_zone":"America\/Detroit", "event_title":" International Students Career Series: How to Build Your Network", "occurrence_title":"", "combined_title":" International Students Career Series: How to Build Your Network", "event_subtitle":"", "event_type":"Careers \/ Jobs", "event_type_id":"2", "description":"You can\u2019t start networking unless you know where to begin! For many international students, the idea of approaching and interacting with professionals in the U.S. can feel intimidating \u2014 and that\u2019s okay. In this interactive workshop, you\u2019ll learn practical strategies forfinding and connecting with contacts, as well as how to conduct informational interviews. These conversations let you explore careers and companies by hearing directly from professionals about their day-to-day work \u2014 without the pressure of a formal job interview.Networking is all about building genuine relationships, and often those connections can lead to exciting opportunities down the road. This session is open to all students. For a head start, check out our website before attending to familiarize yourself with the basics.Review Networking Resources: https:\/\/www.youtube.com\/watch?v=8PHpx31Amwc&t=2shttps:\/\/careercenter.umich.edu\/article\/networking-resources\u00a0This event's information is shown in Handshake as well as on the Happening @ Michigan calendar so that it will be seen by a larger number of U-M Students. You can only register to attend this event within Handshake. If you'd liketo indicate that you'll be attending this event and see more details, please go to this webpage: https:\/\/umich.joinhandshake.com\/events\/2039291\/share_previewWe want to ensure full and equitable participation in our events. If an accessibility accommodation would promote your full participation in this event, please indicate your accommodation requirements via the link below, preferably at least 14 days prior to the program to ensure sufficient time for arranging your requested accommodation(s) or exploring suitable alternatives. If you have any questions regarding access to our programs, please don't hesitate to reach out to Jocelyn Gaydos at jmgaydos@umich.edu. Accessibility accommodation form: https:\/\/forms.gle\/FmFn35ZLxJ8kvPfSA\u00a0#UCC", "occurrence_notes":null, "guid":"153438-21915858@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/153438", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"", "has_livestream":0, "cost":"", "tags":[], "website":"", "sponsors":[ { "group_name":"University Career Center UCC", "group_id":"1140", "website":"http:\/\/careercenter.umich.edu" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21915858 } , "153123-21915121": { "datetime_modified":"20260930T145225", "datetime_start":"20261103T110000", "datetime_end":"20261103T130000", "has_end_time":1, "date_start":"2026-11-03", "date_end":"2026-11-03", "time_start":"11:00:00", "time_end":"13:00:00", "time_zone":"America\/Detroit", "event_title":"FA26 MSminor Colloquium", "occurrence_title":"", "combined_title":"FA26 MSminor Colloquium", "event_subtitle":"", "event_type":"Presentation", "event_type_id":"16", "description":"The Museum Studies Minor program is hosting its Fall 2026 Colloquium. Museum Studies Minor students will share their experience during their internships.", "occurrence_notes":null, "guid":"153123-21915121@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/153123", "building_id":"1000152", "building_name":"Tisch Hall", "campus_maps_id":"541", "room":"G026", "location_name":"Tisch Hall", "has_livestream":0, "cost":"", "tags":["museum studies program","museum studies"], "website":"", "sponsors":[ { "group_name":"Museum Studies Program", "group_id":"1801", "website":"" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21915121 } , "151306-21911347": { "datetime_modified":"20261103T102104", "datetime_start":"20261103T110000", "datetime_end":"20261103T140000", "has_end_time":1, "date_start":"2026-11-03", "date_end":"2026-11-03", "time_start":"11:00:00", "time_end":"14:00:00", "time_zone":"America\/Detroit", "event_title":"IPE Study Abroad Fair", "occurrence_title":"", "combined_title":"IPE Study Abroad Fair", "event_subtitle":"", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"IPE will host a STUDY ABROAD FAIR- for engineering students on Tuesday, November 3 in Pierpont Commons.\u00a0Stop by and talk with advisors and students who studied abroad to learn more!Plus Games & Prizes!ATtend to Win a $1,000 travel grant", "occurrence_notes":null, "guid":"151306-21911347@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/151306", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"Pierpont Commons", "has_livestream":0, "cost":"", "tags":["Sessions"], "website":"https:\/\/sessions.studentlife.umich.edu\/p\/track\/17769", "sponsors":[ { "group_name":"Sessions @ Michigan", "group_id":"4791", "website":"https:\/\/sessions.studentlife.umich.edu\/" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21911347 } , "153927-21916755": { "datetime_modified":"20261021T141949", "datetime_start":"20261103T110000", "datetime_end":"20261103T120000", "has_end_time":1, "date_start":"2026-11-03", "date_end":"2026-11-03", "time_start":"11:00:00", "time_end":"12:00:00", "time_zone":"America\/Detroit", "event_title":"MCDB Dissertation Defense Seminar> The Regulation and Interactome of an H4K20-Specific Demethylase in Dosage Compensation of C. elegans", "occurrence_title":"", "combined_title":"MCDB Dissertation Defense Seminar> The Regulation and Interactome of an H4K20-Specific Demethylase in Dosage Compensation of C. elegans: Anati Alyaa Binti Azhar", "event_subtitle":"Anati Alyaa Binti Azhar", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"In species that use sex chromosomes to differentiate between its sexes, there is a difference in sex chromosome number and the number of gene copies which results in unequal gene dosage. In species that cannot tolerate this imbalance in gene dosage, the dosage compensation process is applied in which the gene expression levels between the two sexes are made equal. In mammals, female somatic cells (XX) have one X chromosome inactivated to equalize to the single X chromosome in male somatic cells (XY). In C. elegans, hermaphrodites (XX) downregulate both X chromosomes by half to equalize to the single X chromosome in their male counterparts (XO). \n\nDosage compensation in C. elegans is conducted primarily by the Dosage Compensation Complex (DCC), a multimeric set of proteins including a CondensinIDC complex and several additional proteins that bind, compact and downregulate the X chromosomes in hermaphrodites. One of the non-condensin proteins in the DCC is DPY-21, a Histone 4 Lysine 20 (H4K20)- specific demethylase. DPY-21 binds to the hermaphroditic X chromosomes and converts H4K20 di-methylation (H4K20me2) into mono-methylation (H4K20me1). This results in the enrichment of the repressive H4K20me1 mark on the X and the transcriptional downregulation of the X chromosomes. Although DPY-21 is part of the DCC, it localizes to the X chromosomes at a later stage of embryogenesis and does not bind mitotic chromosomes, contrasting to the other DCC components. Additionally, DPY-21 has been shown to have a DCC-independent role in the germline where dosage compensation in unrequired. This drives the question of the regulation of DPY-21 and its interactors in addition to the DCC. \n\nThe first part of my thesis is the characterization of DPY-21 regulation through phosphorylation. Using CRISPR\/Cas9 site-directed mutagenesis, I generated a dpy-21 phosphomutant C.elegans strain by mutating the phosphosites of DPY-21 into Alanines to render them non-phosphorylatable. Through physiological assays, I found that the dpy-21 phosphomutant C. elegans strain has defects in embryogenesis and larval stages. In embryogenesis, the phosphomutations disrupts DPY-21\u2019s localization to the X chromosomes and delays the enrichment of H4K20me1 to the X chromosomes. Through biochemical and imaging analysis, I demonstrate that the global levels of 4K20me1 is increased in the phosphomutant strain, suggesting that the mutant protein may be hyperactive. At the larval stages, the dpy-21 phosphomutant strain exhibits developmental delay and increased propensity to form dauers. These defects are resolved by adulthood which implies that DPY-21\u2019s activity is most critical in the embryonic and larval stages.\n\nThe second part of my work revealed novel interactors of DPY-21. I conducted an immunoprecipitation-mass spectrometry (IP-MS ) on DPY-21 to establish its interacting partners and found the kinase SPK-1 to be a top interactor of DPY-21. In spk-1 mutants, there is delayed H4K20me1 enrichment on the X chromosomes in embryogenesis which ultimately results in disrupted H4K20me1 enrichment on the X chromosomes in adults. This shows that SPK-1 may regulate DPY-21 although this may be indirect. Taken together, my work has characterized a novel dpy-21 mutant for the field that leads to its hyperactivity in generating H4K20me1 globally as well as the novel interactor SPK-1 that may regulate DPY-21.", "occurrence_notes":null, "guid":"153927-21916755@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/153927", "building_id":"1005169", "building_name":"Biological Sciences Building", "campus_maps_id":"631", "room":"1010", "location_name":"Biological Sciences Building", "has_livestream":0, "cost":"", "tags":["Thesis Defense","Graduate Students","Bsbsigns","Biology"], "website":"https:\/\/lsa.umich.edu\/mcdb\/news-events\/all-events.html#q=&filter=&start=&end=10\/21\/2027&tags=", "sponsors":[ { "group_name":"Department of Molecular, Cellular, and Developmental Biology", "group_id":"3755", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/10\/event_153927_original-1.jpg", "styled_images":{ 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"time_zone":"America\/Detroit", "event_title":"The Allocative Cost of War: A View to a Kill. . .ing of Productivity", "occurrence_title":"", "combined_title":"The Allocative Cost of War: A View to a Kill. . .ing of Productivity: Yuriy Gorodnichenko, University of California, Berkeley", "event_subtitle":"Yuriy Gorodnichenko, University of California, Berkeley", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Why is war so economically costly? Our answer is that modern war lowers output not only by destroying productive factors, but also by making the surviving economy work less efficiently. Using uniquely comprehensive firm-level data collected during Russia\u2019s full-scale invasion of Ukraine in 2022, we document a dramatic collapse in allocative productivity in Ukraine. To sharpen identification and explore key mechanisms (including the role of war intensity, internal displacement, reallocation, and macroeconomic instability), we exploit spatial heterogeneity across Ukrainian districts and comparisons with Russian aggression in 2014 and the 2008 Global Financial Crisis. Our key policy implication is that restoring allocative efficiency\u2013and preparing institutional arrangements that facilitate rapid reallocation in times of stress\u2013is critical for sustaining economic capacity, defense, and national security.", "occurrence_notes":null, "guid":"149568-21906713@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/149568", "building_id":"1005177", "building_name":"North Quad", "campus_maps_id":"553", "room":"4325", "location_name":"North Quad", "has_livestream":0, "cost":"", "tags":["seminar","Macroeconomics","Economics"], "website":"http:\/\/www.lsa.umich.edu\/econ", "sponsors":[ { "group_name":"Department of Economics", "group_id":"3302", "website":"http:\/\/www.lsa.umich.edu\/econ" }, { "group_name":"Michael Beauregard Seminar in Macroeconomics", "group_id":"3552", "website":"" }, { "group_name":"Department of Economics Seminars", "group_id":"3566", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/07\/event_149568_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2026\/07\/event_149568_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/07\/event_149568_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2026\/07\/event_149568_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2026\/07\/event_149568_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2026\/07\/event_149568_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2026\/07\/event_149568_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2026\/07\/event_149568_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2026\/07\/event_149568_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2026\/07\/event_149568_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2026\/07\/event_149568_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2026\/07\/event_149568_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2026\/07\/event_149568_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2026\/07\/event_149568_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2026\/07\/event_149568_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2026\/07\/event_149568_original-1.png" }, "occurrence_count":1, "first_occurrence":21906713 } }