{
    "150650-21909759":
    {
        "datetime_modified":"20260924T111012",
        "datetime_start":"20260930T160000",
        "datetime_end":"20260930T170000",
        "has_end_time":1,
        "date_start":"2026-09-30",
        "date_end":"2026-09-30",
        "time_start":"16:00:00",
        "time_end":"17:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"CCMB\/DCMB Weekly Bioinformatics Seminar Series featuring Jianzhi Zhang, PhD (Professor, Ecology and Evolutionary Biology, U-M)",
        "occurrence_title":"",
        "combined_title":"CCMB\/DCMB Weekly Bioinformatics Seminar Series featuring Jianzhi Zhang, PhD (Professor, Ecology and Evolutionary Biology, U-M): \"Multi-environment fitness landscapes suggest effectively endless adaptation\"",
        "event_subtitle":"\"Multi-environment fitness landscapes suggest effectively endless adaptation\"",
        "event_type":"Workshop \/ Seminar",
        "event_type_id":"21",
        "description":"Jianzhi (George) Zhang is a Professor of Ecology and Evolutionary Biology interested in the relative roles of chance and necessity in evolution. He got his B. S. from Fudan University in Shanghai, China, and his Ph. D. in Genetics from Pennsylvania State University. He was a  Fogarty postdoctoral fellow at the National Institute of Allergy and Infectious Diseases before moving to the University of Michigan.\n\nAbstract\n\nAdaptive evolution proceeds through beneficial nucleotide substitutions in the genome, yet the number of such substitutions (N) required to reach a local or global fitness peak where no single mutation further increases fitness remains unknown. Here we estimate N by simulating adaptive walks on two large, complete, multi-environment adaptive landscapes inferred from massive empirical data using machine learning, with validation from smaller experimentally mapped landscapes. We find that N rises linearly with the number of variable sites (L) in the landscape, regardless of prior adaptation in another environment. Extrapolation suggests a minimal N of 10^5 for typical prokaryotes and 10^7 for mammals. By contrast, in highly rugged shuffled landscapes, N is markedly reduced, while fitness gains also shrink. The relatively smooth empirical landscapes therefore enable greater fitness gains while lengthening adaptive walks, rendering even local fitness peaks effectively unreachable before environments change. These results explain the persistence of fitness gains in long-term evolution experiments and the widespread occurrence of beneficial mutations across species. They suggest that populations continuously adapt while remaining far from fitness optima, challenging the long-held view that adaptation culminates at fitness peaks.",
        "occurrence_notes":null,
                "guid":"150650-21909759@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/150650",
        "building_id":"1000190",
        "building_name":"Medical Science Unit I",
        "campus_maps_id":"104",
        "room":"4B700",
        "location_name":"Medical Science Unit I",
        "has_livestream":0,
        "cost":"",
        "tags":["Genome","Basic Science","Bioinformatics","Biology","Biosciences","Ecology"],
        "website":"https:\/\/umich.zoom.us\/j\/93929606089?pwd=SHh6R1FOQm8xMThRemdxTEFMWWpVdz09",
        "sponsors":[
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                "group_id":"3754",
                "website":""                },             {
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    {
        "datetime_modified":"20260926T002115",
        "datetime_start":"20260930T160000",
        "datetime_end":"20260930T180000",
        "has_end_time":1,
        "date_start":"2026-09-30",
        "date_end":"2026-09-30",
        "time_start":"16:00:00",
        "time_end":"18:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Distinguished University Professor Lectureship Series",
        "occurrence_title":"Distinguished University Professorship Lecture Series",
        "combined_title":"Distinguished University Professor Lectureship Series: Distinguished University Professorship Lecture Series",
        "event_subtitle":"",
        "event_type":"Workshop \/ Seminar",
        "event_type_id":"21",
        "description":"Sponsored by the Office of the President and the Office of the Provost, this event features three Distinguished University Professors speaking on their professional and scholarly experiences. Each concise lecture will be followed by a brief Q & A.\u00a0\u201cThe 1857 Indian Revolution and the Rubaiyat of Omar Khayyam\u201d by Juan Cole (Richard P. Mitchell Distinguished University Professor of History and Professor of History, College of Literature, Science, and the Arts).\n\"Paying Attention\" by John Jonides (Edward E. Smith Distinguished University Professor of Psychology and Neuroscience, Co-Director, Magnetic Resonance Imaging Facility, Professor of Radiology, Medical School and Professor of Psychology, College of Literature, Science, and the Arts).\n\u201cStudying Aging and Dementia in Patients and Populations\u201d by Kenneth Langa (A. Regula Herzog Distinguished University Professor of Internal Medicine and Survey Research, Cyrus Sturgis Research Professor of Internal Medicine, Professor of Internal Medicine, Research Professor, Institute of Gerontology, Medical School, Research Professor, Survey Research Center, Institute for Social Research).\nNot able to attend in person? The event will be available via livestream here.",
        "occurrence_notes":null,
                "guid":"149970-21907457@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/149970",
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        "room":"",
        "location_name":"Michigan League Ballroom",
        "has_livestream":0,
        "cost":"",
        "tags":["Sessions"],
        "website":"https:\/\/sessions.studentlife.umich.edu\/p\/track\/17435",
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                "group_name":"Sessions @ Michigan",
                "group_id":"4791",
                "website":"https:\/\/sessions.studentlife.umich.edu\/"                }                    ],
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    }    ,    "149935-21907396":
    {
        "datetime_modified":"20260917T115242",
        "datetime_start":"20260930T160000",
        "datetime_end":"20260930T180000",
        "has_end_time":1,
        "date_start":"2026-09-30",
        "date_end":"2026-09-30",
        "time_start":"16:00:00",
        "time_end":"18:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Distinguished University Professorship Lecture Series",
        "occurrence_title":"",
        "combined_title":"Distinguished University Professorship Lecture Series",
        "event_subtitle":"",
        "event_type":"Lecture \/ Discussion",
        "event_type_id":"13",
        "description":"Sponsored by the Office of the President and the Office of the Provost, this event features three Distinguished University Professors speaking on their professional and scholarly experiences. Each concise lecture will be followed by a brief Q & A.\n\n\u201cThe 1857 Indian Revolution and the Rubaiyat of Omar Khayyam\u201d by Juan Cole (Richard P. Mitchell Distinguished University Professor of History and Professor of History, College of Literature, Science, and the Arts).\n\n\"Paying Attention\" by John Jonides (Edward E. Smith Distinguished University Professor of Psychology and Neuroscience, Co-Director, Magnetic Resonance Imaging Facility, Professor of Radiology, Medical School and Professor of Psychology, College of Literature, Science, and the Arts).\n\n\u201cStudying Aging and Dementia in Patients and Populations\u201d by Kenneth Langa (A. Regula Herzog Distinguished University Professor of Internal Medicine and Survey Research, Cyrus Sturgis Research Professor of Internal Medicine, Professor of Internal Medicine, Research Professor, Institute of Gerontology, Medical School, Research Professor, Survey Research Center, Institute for Social Research).",
        "occurrence_notes":null,
                "guid":"149935-21907396@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/149935",
        "building_id":"1000191",
        "building_name":"Michigan League",
        "campus_maps_id":"108",
        "room":"League Ballroom | Second Floor",
        "location_name":"Michigan League",
        "has_livestream":0,
        "cost":"",
        "tags":["Reception","AEM Featured","dup","lecture"],
        "website":"https:\/\/www.youtube.com\/watch?v=Xpf3lmSnYZ0",
        "sponsors":[
             {
                "group_name":"University and Development Events",
                "group_id":"3213",
                "website":""                },             {
                "group_name":"Department of History",
                "group_id":"3470",
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                "group_name":"Department of Psychology",
                "group_id":"3615",
                "website":"http:\/\/www.lsa.umich.edu\/psych\/"                }                    ],
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    }    ,    "151752-21912119":
    {
        "datetime_modified":"20260908T151707",
        "datetime_start":"20260930T160000",
        "datetime_end":"20260930T170000",
        "has_end_time":1,
        "date_start":"2026-09-30",
        "date_end":"2026-09-30",
        "time_start":"16:00:00",
        "time_end":"17:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"German Convo on the Go",
        "occurrence_title":"",
        "combined_title":"German Convo on the Go",
        "event_subtitle":"",
        "event_type":"Social \/ Informal Gathering",
        "event_type_id":"19",
        "description":"Meet at Burton Tower for a 1-hour walk and talk in German with Mary Gell (magell@umich.edu). This event happens 'rain or shine.' Open to speakers of German at all levels.",
        "occurrence_notes":null,
                "guid":"151752-21912119@events.umich.edu",
        "permalink":"http:\/\/events.umich.edu\/event\/151752",
        "building_id":"1000155",
        "building_name":"Burton Memorial Tower",
        "campus_maps_id":"25",
        "room":"Meet Outside the Tower",
        "location_name":"Burton Memorial Tower",
        "has_livestream":0,
        "cost":"",
        "tags":["German Studies","Language","Germanic Languages And Literatures","Humanities","German","European"],
        "website":"",
        "sponsors":[
             {
                "group_name":"Germanic Languages & Literatures",
                "group_id":"3621",
                "website":"http:\/\/www.facebook.com\/umichGerman\/"                }                    ],
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    }    ,    "152157-21913156":
    {
        "datetime_modified":"20260914T181717",
        "datetime_start":"20260930T160000",
        "datetime_end":"20260930T172000",
        "has_end_time":1,
        "date_start":"2026-09-30",
        "date_end":"2026-09-30",
        "time_start":"16:00:00",
        "time_end":"17:20:00",
        "time_zone":"America\/Detroit",
        "event_title":"Leyya Mona Tawil and collaborators in \"Happy Days Finale\"",
        "occurrence_title":"",
        "combined_title":"Leyya Mona Tawil and collaborators in \"Happy Days Finale\": Work-in-progress showing followed by Q&A",
        "event_subtitle":"Work-in-progress showing followed by Q&A",
        "event_type":"Performance",
        "event_type_id":"15",
        "description":"Join us for an informal showing of *Happy Days Finale*, a new performance work by Leyya Mona Tawil in collaboration with Zari Lionudakis (dance), John MacDoughall Parker (music), and Scott Tallenger (costume).\n\nWhat does happiness mean in a time of revolution? With each day anew, what is our capacity for communion, grief, resistance, chance? In a world of relentless injustice and collapse, we question what is ending and what is beginning. DANCE ELIXIR's *Happy Days Finale* is an invitation to test these questions, in body and time.\n\nAt the heart of *Happy Days Finale* is Tawil\u2019s \u201cchoice-based choreography,\u201d where each performance unfolds uniquely. The dance composition is driven by decisions that transform the work into an ever-evolving conversation between movement, space, and sound. Tawil calls it \u201can act of agility and adaptability,\u201d - a dance that contains multiple truths with every iteration.\n\n*Happy Days Finale* is an invitation to think critically and collaboratively, to explore how we, as a community, can face the challenges of today\u2019s world. Tawil has created a space for modeling new ways of being in an unpredictable world. *Happy Days Finale* proposes dancemaking as a potent tool for liberation, urging us to question, to mourn, and to labor, together.\n\nPresented by Daring Dances and the Center for World Performance Studies.\n\n*If you are a person with a disability who requires an accommodation to participate in this event, please contact the Center for World Performance Studies at cwps.information@umich.edu at least one week in advance of this event. Please be aware that advance notice is necessary as some accommodations may require more time for the University to arrange.*\n\nBIOGRAPHIES\n\nLEYYA MONA TAWIL, Conceptual Score, Choreography, and Performance\nDirector of DANCE ELIXIR, Leyya Mona Tawil is an artist, performer, and cultural activist working in hybrid performance practices. Tawil is Palestinian and Syrian; engaged in the world as such. Her choreographies and sound projects have been presented throughout the states, Europe, and the Arab world. Highlight engagements: \u201cMy Name is Palestine\u201d exhibit at Southern Exposure (SF), performance commissions from Abrons Arts Center (NYC) and Sibelius Museum (Turku), and residencies with Sharjah Art Foundation (UAE), Wysing Arts\/British Council (UK) and PlayHouse Labs (Detroit). Tawil was nominated for a 2019 \u201cBessies\u201d Award in Music (NYC) and received the Ruth Arts Artist Choice Award 2026. She has stewarded TAC Temescal Art Center in Oakland since 1997, and is the founding director of Arab.AMP - a platform for worldbuilding artists from the Arab\/SWANA diaspora and our allied communities.\n\nZARI LIONUDAKIS, Dance Collaborator and Performer\nZari Lionudakis is an artist and educator who challenges perceptions of either\/or. A lone wolf in lineage, heritage and praxis, Zari's work in liminal space bleeds into her performance, technique classes, scholarship and healing modalities. The late historian Hayden White called Zari a \"radical visionary,\" as every mode of Zari's work challenges existing notions of what \"is.\" Whether ballet or vernacular, slang or scholarship, Zari uses languages that work towards liberation. She has performed extensively with DANCE ELIXIR since its founding in 2003.\n\nJOHN MACDOUGALL PARKER, Music Collaborator and Performer\nJohn MacDougall Parker creates improvisational future-folk compositions where sound is amalgamated and congealed into a resolution of crossed signals. He has devised instruments focused on the interface between humans and machines, which are arranged to make music in the moment. Parker, of American and Korean origin, floats between NYC and S\u00e3o Paulo.\n\nSCOTT TALLENGER, Costumes\nScott Tallenger is a Left-Handed\/Right Brained, photographer, skateboarder and fashion designer. Based in Detroit and working nationally, Scott specializes in one-of-a-kind event garments and accessories.  His first costume collaboration with performer Leyya Mona Tawil was in 2006, and he has since created over 11 unique costumes for DANCE ELIXIR.",
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        "building_name":"Off Campus Location",
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        "room":"",
        "location_name":"Multipurpose Room, Trotter Multicultural Center, 428 S State St, Ann Arbor, MI 48109",
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        "cost":"Free - no tickets required",
        "tags":["Talk","Discussion","Dance","Free","Music","Social Impact"],
        "website":"",
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                "group_id":"155",
                "website":"http:\/\/smtd.umich.edu\/events"                },             {
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        "description":"Abstract: Recently the TCS query learning ala Nisan--Mansur--Linial got the boost from a harmonic analysis random algorithm. This problem has a non-commutative version where one needs to learn a very big matrix (so-called d-local hamiltonians) from  a few random queries.\nThe corresponding harmonic analysis results have a drawback that it is still not known how tight they are. We will discuss this and show tightness for some of them. Interestingly, one such tightness result is closely related to Einstein--Podolsky--Rosen paradox from quantum mechanics. On a close issue: arguably the main problem in understanding the speed up  of quantum algorithms versus classical ones for a certain collection of problems (called Aaronson--Ambainis conjecture and still open) will be discussed too if time permits.",
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