{ "152899-21914734": { "datetime_modified":"20260925T170255", "datetime_start":"20261015T143000", "datetime_end":"20261015T160000", "has_end_time":1, "date_start":"2026-10-15", "date_end":"2026-10-15", "time_start":"14:30:00", "time_end":"16:00:00", "time_zone":"America\/Detroit", "event_title":"Understanding the K-12 STEM Ecosystem in Michigan: Strengthening U-M\u2019s Contribution", "occurrence_title":"", "combined_title":"Understanding the K-12 STEM Ecosystem in Michigan: Strengthening U-M\u2019s Contribution", "event_subtitle":"", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"Organizational change for student success begins well before college. Join campus leaders and experts for an in-depth look at the K-12 and pre-college STEM ecosystem in Michigan that shapes students' pathways long before they enter higher education. This session connects research to practice by examining the current status of STEM education in the state, lessons learned from U-M's Wolverine Pathways program, and identifying concrete opportunities to deepen U-M\u2019s contribution toward sustained institutional and statewide impact.\n\n\nFeaturing:\n\nDeborah Loewenberg Ball, Jessie Jean Storey-Fry Distinguished University Professor of Education, University of Michigan\n\nCarla O\u2019Connor, Director, Wolverine Pathways and University Diversity and Social Transformation Professor, University of Michigan\n\nMegan Schrauben, MiSTEM Network Executive Director\n\n\nAbout the series:\n\nReimagining STEM Student Success is a new series designed to advance the recommendations of the STEM Success Working Group by positioning organizational change as the primary lever for student success. Across five sessions, expert insights will connect research to concrete U-M practices to transform our campus systems, cultures, and structures.\n\n\nSponsors:\n\nAccess & Opportunity; Center for Educational Outreach (CEO); Comprehensive Studies Program; Michigan Program for Advancing Cultural Transformation (M-PACT); Office of Faculty Development at the U-M Medical School; Office of the Vice Provost for Undergraduate Education; Student Success Initiative; Phillip J. Bowman Center for Scholarship to Practice; UROP: A Center for Research, Scholarship and Creative Inquiry", "occurrence_notes":null, "guid":"152899-21914734@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/152899", "building_id":"1000120", "building_name":"Michigan Union", "campus_maps_id":"191", "room":"Pendleton", "location_name":"Michigan Union", "has_livestream":0, "cost":"", "tags":["AEM Featured"], "website":"https:\/\/myumi.ch\/9Jq61", "sponsors":[ { "group_name":"Phillip J. Bowman Center for Scholarship to Practice", "group_id":"3258", "website":"http:\/\/bowmancenter.umich.edu" }, { "group_name":"Comprehensive Studies Program CSP", "group_id":"1051", "website":"" }, { "group_name":"Center for Educational Outreach", "group_id":"3607", "website":"" }, { "group_name":"UROP - Undergraduate Research Opportunity Program", "group_id":"3702", "website":"https:\/\/twitter.com\/UROPumich" }, { "group_name":"Michigan Program for Advancing Cultural Transformation (M-PACT)", "group_id":"5262", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/09\/event_152899_original-2.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2026\/09\/event_152899_original-2.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/09\/event_152899_original-2.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2026\/09\/event_152899_original-2.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2026\/09\/event_152899_original-2.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2026\/09\/event_152899_original-2.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2026\/09\/event_152899_original-2.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2026\/09\/event_152899_original-2.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large_lightbox\/media\/attachments\/2026\/09\/event_152899_original-2.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2026\/09\/event_152899_original-2.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2026\/09\/event_152899_original-2.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2026\/09\/event_152899_original-2.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2026\/09\/event_152899_original-2.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2026\/09\/event_152899_original-2.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_large\/media\/attachments\/2026\/09\/event_152899_original-2.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2026\/09\/event_152899_original-2.png" }, "occurrence_count":1, "first_occurrence":21914734 } , "153338-21915654": { "datetime_modified":"20261006T070018", "datetime_start":"20261015T150000", "datetime_end":"20261015T160000", "has_end_time":1, "date_start":"2026-10-15", "date_end":"2026-10-15", "time_start":"15:00:00", "time_end":"16:00:00", "time_zone":"America\/Detroit", "event_title":"Biomedical Engineering (BME 500) Seminar Series", "occurrence_title":"", "combined_title":"Biomedical Engineering (BME 500) Seminar Series: \"Immunoengineered Platforms for Type 1 Diabetes,\" with Alice Tomei, Ph.D.", "event_subtitle":"\"Immunoengineered Platforms for Type 1 Diabetes,\" with Alice Tomei, Ph.D.", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Immunoengineered Platforms for Type 1 Diabetes\n\nAbstract:\nImmunoengineering applies quantitative problem-solving and engineering tools\u2014such as biomaterials and cellular and protein engineering\u2014to address complex challenges in human health that traditional biomedical science alone cannot solve. In this seminar, Dr. Tomei will present advanced immunoengineering platforms designed for targeted interventions in type 1 diabetes (T1D), focusing on two main frontiers: disease prevention via antigen-specific tolerance and safer, more effective beta-cell replacement therapies.\n\nFor T1D Prevention: Dr. Tomei will discuss the development of macroporous scaffold slices designed to harness the tolerogenic properties of lymph node fibroblastic reticular cells via transplantation in murine models. Additionally, she will show the development of decellularized lymph node scaffold sections to demonstrate that the pro-inflammatory T1D lymph node environment reprograms stromal cells into a diabetes-prone phenotype. These insights aim to inspire antigen-specific preventive approaches that avoid the risks of broad systemic immunosuppression.\n\nFor T1D Treatment: She will address the limitations of islet encapsulation in confined transplantation sites. To tackle this, she will introduce an in vitro platform built to investigate the relative contributions of direct versus indirect allorejection. Furthermore, she will present a biomaterial platform engineered with IgG-brining peptides for the sustained, localized delivery of biological drugs (such as co-stimulatory blockers and anti-inflammatory agents). This approach achieves allograft survival rates comparable to systemic drug administration while eliminating systemic spillover and avoiding the associated risks of immunodeficiency. Finally, Dr. Tomei will demonstrate the feasibility of achieving localized immunomodulation at the islet transplantation site through the co-delivery of islet-alloantigen-primed tolerogenic lymph node stromal cells. Overall, these approaches could expand the safety and clinical applicability of beta-cell replacement therapy. \n\nBio:\nDr. Alice Tomei is the Dr. Leonard and Diane F. Pinchuk Family Associate Professor of Biomedical Engineering at the University of Miami, with secondary appointments in Surgery, Microbiology and Immunology, and Molecular and Cellular Pharmacology. She earned her M.S. in Materials Engineering from the Politecnico di Milano, Italy, in 2004 and her Ph.D. in Bioengineering and Biotechnology from the \u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne (EPFL), Switzerland, in 2008.\n\nDr. Tomei directs the Islet Immunoengineering Laboratory at the Diabetes Research Institute (DRI), where her research integrates bioengineering, biomaterials, and immunology to develop innovative immunoengineering strategies for localized immune modulation, improving islet transplantation outcomes and inducing antigen-specific immune tolerance as a path toward a cure for type 1 diabetes. Her research program is supported by the National Institutes of Health (NIH) and Breakthrough T1D.\n\nDr. Tomei has trained and mentored 5 postdoctoral fellows, 15 Ph.D. students, 22 M.S. students, 34 undergraduate students, and 4 high school students in the fields of tissue engineering and immunoengineering. She has served as a standing member of the NIH BMBI Study Section and is currently President-Elect of the Cell Transplant and Regenerative Medicine Society (CTRMS).\n\nHer contributions have been recognized with numerous honors, including the JDRF Career Development Award, the Eliahu I. Jury Early Career Research Award, the Alexander Orr Excellence in Teaching Award, the Young Innovator in Cellular and Molecular Bioengineering Award, and the Johnson A. 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