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        "event_title":"Biomedical Engineering Seminar Series",
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        "combined_title":"Biomedical Engineering Seminar Series: \"Learning What Matters: Neural Mechanisms of Flexible Navigation,\" with Annabelle Singer, Ph.D.",
        "event_subtitle":"\"Learning What Matters: Neural Mechanisms of Flexible Navigation,\" with Annabelle Singer, Ph.D.",
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        "description":"Learning What Matters: Neural Mechanisms of Flexible Navigation\r\nAbstract:\r\nGoal-directed navigation in a dynamic world requires quickly identifying important locations and adapting behavioral plans to new information. In this talk I will describe neural circuit mechanisms of rapid spatial learning and of adapting to new information to guide navigation. Identifying crucial locations in a new environment depends on neural computations that rapidly represent locations and connect location information to key outcomes like food, however the mechanisms to trigger these computations at behaviorally relevant locations is not well understood. We find that inhibitory interneurons in hippocampal CA3 play a causal role in identifying and exploiting new food locations. Inhibitory interneurons in CA3 drastically reduce firing on approach to and in goal locations. Sparse optogenetic stimulation to prevent goal-related decreases in interneuron firing impaired learning of goal locations and disrupted neural representations of goal locations. These results reveal that goal-selective decreases in inhibitory activity enable learning important locations. Navigation also requires rapidly updating choices in the face of new information. In hippocampus and prefrontal cortex, neural activity representing future goals is theorized to support navigation planning. Yet how prospective goal representations incorporate new, pivotal information is unknown. Using virtual reality, we precisely introduced new crucial information during navigation and recorded neural activity as mice flexibly adapted their planned destinations. We found that new information triggered increased prospective representations and reorganization to rapidly shift to the new choice. This prospective code updating depended on the degree of behavioral adaptation needed. These studies reveal new mechanisms by which animals rapidly learn crucial new locations and adapt to new information that requires updating navigation plans.\r\n\r\nBio:\r\nDr. Annabelle Singer is the McCamish Foundation Early Career Professor in the Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. Her research seeks to understand how neural activity produces memories and regulates brain immune function, with the goal of developing new therapies for brain disease. Dr. Singer\u2019s work has shown that coordinated electrical activity across hippocampal neurons encodes memories and fails in models of Alzheimer\u2019s disease. She discovered that driving specific patterns of neural activity, such as gamma oscillations, reduces Alzheimer\u2019s pathology and alters brain immune function. Using non-invasive sensory stimulation, she is translating these discoveries from rodents to humans to pioneer radically new treatments for disease.\r\n\r\nDr. Singer is a Packard Fellow, Kavli Fellow, and recipient of the National Academy of Engineering\u2019s Gilbreth Lectureship, the Society for Neuroscience\u2019s Janett Rosenberg Trubatch Career Development Award, and the American Neurological Association\u2019s Derek Denny-Brown Young Neurological Scholar Award. Her discoveries have inspired more than 20 clinical trials of brain stimulation across multiple diseases and have been featured on PBS, Nature News, Quanta Magazine, The New York Times, Radiolab, and multiple documentaries. Dr. Singer trained as a postdoctoral fellow in Ed Boyden\u2019s Synthetic Neurobiology Group at MIT and earned her Ph.D. in Neuroscience at UCSF.",
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        "event_title":"Participatory Storytelling & Theater Workshop",
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        "description":"The Center for World Performance Studies welcomes guest artists Ova Saopeng and Stephanie \u201cSoultree\u201d Camba from TeAda Productions, the Los Angeles-based nomadic theater rooted in the stories of immigrants, refugees and indigenous peoples for a week-long residency.\n\nAt this workshop, come play in a safe and fun environment and discover the untapped capability of your voice, body and imagination. Through theater and storytelling techniques the TeAda Methodology instills mindfulness, builds teamwork, and explores cultural connections. TeAda approaches this process by honoring each person individually as a community collectively. This workshop will fine tune your listening, observational and performance skills. Participants will be encouraged to engage, move and share. No experience necessary!\n\nWorkshop Location: Walgreen Drama Center, Studio 2 (1435-WDC)\n\nWorkshop participants are invited to join TeAda Co-Artistic Director, Ova Saopeng, and Stephanie \u201cSoultree\u201d Camba, Diaspora Programs and Operations Director, for conversation and pizza following the open workshop. \n\nPizza & Dialogue with TeAda Artists at 5:30 pm \/ Location: Dance Building, Conference Room\n\n*If you are a person with a disability who requires an accommodation to participate in this event, please contact the Center for World Performance Studies at cwps.information@umich.edu at least one week in advance of this event. Please be aware that advance notice is necessary as some accommodations may require more time for the University to arrange.*",
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        "event_title":"The Department of Astronomy 2025-2026 Colloquium Series Presents:",
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        "combined_title":"The Department of Astronomy 2025-2026 Colloquium Series Presents:: Dr. Erik Peterson & Dr. Nicholas Kern Post Doc Colloquium",
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        "event_title":"2026 Leadership Crisis Challenge",
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        "description":"The application window for the 2026 Leadership Crisis Challenge opens on Wednesday, January 7!\r\n\r\nABOUT\r\nLeadership Crisis Challenge (LCC) is a premier action-based learning experience that immerses participants in a simulated business and media crisis, powered by the Sanger Leadership Center at Michigan Ross. Students play the part of executives responding to the issues as they unfold, while leveraging the expertise of communication coaches, faculty, and a board of directors made up of esteemed U-M alumni, to prepare for a press conference attended by real members of the media.\r\n\r\nLCC is open to ALL U-M students. There are two levels of competition\u2014graduate and undergraduate. Two undergraduate teams and two graduate teams will receive a scholarship, split among participants. In addition to the competition, there will be educational workshops, a networking session, and access to the Big House field.\r\n\r\nDon't miss out on this amazing, one-of-a-kind opportunity! Apply by January 21.\r\n\r\nAGENDA\r\nThursday, January 29, approx. 4\u201310 PM\r\nMichigan Ross\r\n\r\nFriday, January 30, approx. 9 AM\u20135 PM\r\nJack Roth Stadium Club at Michigan Stadium\r\n\u2022 Boardroom Presentation: Teams will be assigned a 55-minute window to present to, and receive feedback from, a board of directors in the morning or early afternoon\r\n\u2022 Press Conference: The final round of competition begins at 3 PM and ends by 5 PM\r\nSee the full agenda on our website.\r\n\r\nTIME COMMITMENT\r\nApproximately 10 hours over 2 days\r\n\r\nQuestions? Email Sanger at rossleaders@umich.edu.",
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