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        "event_title":"Art On The Move",
        "occurrence_title":"",
        "combined_title":"Art On The Move",
        "event_subtitle":"",
        "event_type":"Fair \/ Festival",
        "event_type_id":"10",
        "description":"What\u2019s Included:\r\nStamps Gallery Tour \u2013 explore contemporary art and meet featured artist Stacey L. Kirby.\r\nFeel Good Friday: Queer Night \u2013 Halloween Edition at UMMA \u2013 a night of queer magic, creativity, and community!\r\n\r\nHighlights at UMMA:\r\nLive performances by Na Bonsai & Cherriel\r\nFilm screenings with Kris McKinney\r\nCostume contest hosted by Baddie Brooks (costumes encouraged, no masks or fake weapons)\r\nMini portraits by ruby flwrs, Miriam Uhura, Yhasmin Wilder, Miranda Kyle\r\nProjections by Venusloc, photobooths & community tables\r\n\r\nTrip Details:\r\nDeparture: 4:00 PM from \r\nUM-Flint- 400 Mill Street Flint, MI 48503\r\nReturn: 11:00 PM\r\n\r\nSnacks provided on the bus\r\n\r\nSeats are limited \u2013 RSVP today!\r\nhttps:\/\/campusconnections.umflint.edu\/CGS\/rsvp_boot?id=382852\r\nEveryone is welcome\u2014don\u2019t miss this chance to explore art, celebrate community, and enjoy a fierce Halloween night out.",
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        "tags":["Michigan Arts Festival","Halloween","Art"],
        "website":"https:\/\/campusconnections.umflint.edu\/CGS\/rsvp_boot?id=382852",
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        "datetime_modified":"20251008T121103",
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        "event_title":"CCMB\/DCMB Special Seminar featuring Hagen Tilgner, PhD (Prof. at Weil Cornell Medical College)",
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        "combined_title":"CCMB\/DCMB Special Seminar featuring Hagen Tilgner, PhD (Prof. at Weil Cornell Medical College): \"A single-cell view of splicing (dys)regulation across in development and the diseases of the brain.\"",
        "event_subtitle":"\"A single-cell view of splicing (dys)regulation across in development and the diseases of the brain.\"",
        "event_type":"Workshop \/ Seminar",
        "event_type_id":"21",
        "description":"Abstract\r\nComplex tissue includes diverse cell types employing distinct RNA isoforms. To untangle full-length cell-type specific brain isoforms, we developed single-cell long-read technology for many thousands of cells (from previous approaches for 10-100 cells) in fresh tissues (ScISOr-Seq; Gupta..Tilgner, 20181) and in frozen tissues (SnISOr-Seq; Hardwick..Tilgner, 20222). These approaches revealed the rules of combination of TSSs, alternative exons and poly(A) sites and their cell-type specificity. Autism-associated exons (as previously described) but also FTD-associated exons are highly variably-used across cell types2. For spatial resolution, we developed spatially-barcoded isoform sequencing with 60um (Joglekar..Tilgner, 20213), 10um (Foord..Tilgner, 20254) and 220nm (Michielsen..Tilgner, biorxiv5) spots, showing that often isoform switches correlate with precise boundaries of brain structures (e.g., choroid plexus to hippocampus). However, genes including Snap25, use a gradient of exon inclusion through the brain3. Choroid plexus epithelial cells show a dramatically distinct isoform profile, which originates most strongly from TSS usage3. During human puberty, layer4-excitatory splicing is more regulated than in other cortical layers \u2013 probably influenced by retroviral sequences4. More generally, we can now detect isoform-expression variability that does not correspond to known brain structures5.\r\n\r\n\r\nFor the NIH Brain Initiative, we have mapped single-cell isoforms across development, brain regions and species. Neurotransmitter release and reuptake as well as synapse turnover genes harbor variability in the same cell type across anatomical regions but the same cell type traced across development shows more isoform variability than across adult anatomical regions. Moreover, most cell-type-specific exons in adult mouse hippocampus behave similarly in human hippocampi. However, human brains have evolved additional cell-type specificity in splicing (Joglekar..Tilgner, 20246). Additionally, the concurrent measurement of chromatin and splicing patterns in post-mortem human brain shows broadly-speaking convergent dysregulation of both modalities in similar cell types in Alzheimer\u2019s disease but more divergence between both modalities in evolution (Hu..Tilgner, 20257). Finally, we have advanced our understanding of error sources of PacBio and ONT (Mikheenko..Tilgner, 20228) and implemented highly accurate long-read software (Prjibelski..Tilgner, 20239).",
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        "tags":["Biology","Basic Science","Bioinformatics","Biosciences","Life Science"],
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        "datetime_start":"20251024T160000",
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        "has_end_time":1,
        "date_start":"2025-10-24",
        "date_end":"2025-10-24",
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        "event_title":"Lessons of Authoritarianism and Democratic Resilience in Latin America:    Cuba's Digital Revolution: Between Quiescence and Revolt",
        "occurrence_title":"",
        "combined_title":"Lessons of Authoritarianism and Democratic Resilience in Latin America:    Cuba's Digital Revolution: Between Quiescence and Revolt: Harold Cardenas Lema and Michaelanne Thomas",
        "event_subtitle":"Harold Cardenas Lema and Michaelanne Thomas",
        "event_type":"Lecture \/ Discussion",
        "event_type_id":"13",
        "description":"A new digital revolution is underway in Cuba. Despite the continued repression of freedoms of speech and assembly, a new generation of Cubans have used digital technologies and social media to fundamentally transform how citizens debate, inform and challenge the authoritarian status quo on the island. From animal rights activists to domestic violence awareness campaigns, to the thousands that took to the streets in cities throughout the island in July 2021, these activities have been organized and documented primarily through new independent digital means. Many young people, intellectuals and artists have developed a whole sector of unique digital spaces for national debate and dialogue to advocate for a more inclusive Cuba. Join us for a dialogue with Dr. Michaelanne Thomas (UMSI) and Harold C\u00e1rdenas Lema, co-founder and former director of one of the foremost digital spaces for Cubans by Cubans on the island, La Joven Cuba.\r\n\r\nAccommodation: If there is anything we can do to make this event accessible to you, please contact us. Please be aware that advance notice is necessary as some accommodations may require more time for the university to arrange.\r\n   Email: -- lacs.office@umich.edu",
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        "tags":["Latin America","Center For Latin American And Caribbean Studies","Discussion","Lecture"],
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                "group_id":"3274",
                "website":"http:\/\/www.ii.umich.edu\/lacs"                },             {
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                "group_id":"1968",
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                "group_name":"Center for Emerging Democracies",
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        "datetime_modified":"20251013T152841",
        "datetime_start":"20251024T160000",
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        "event_title":"Modular embeddings of Fuchsian groups",
        "occurrence_title":"",
        "combined_title":"Modular embeddings of Fuchsian groups: Matthew Stover",
        "event_subtitle":"Matthew Stover",
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        "event_type_id":"21",
        "description":"A Fuchsian group \\Gamma has a modular embedding if its adjoint trace field is a totally real number field and every unbounded Galois conjugate \\Gamma^\\sigma comes equipped with a holomorphic (or conjugate holomorphic) map {\\phi^\\sigma : \\mathbb{B}^1 \\to \\mathbb{B}^1} intertwining the actions of \\Gamma and \\Gamma^\\sigma on the Poincar\u00e9 disk \\mathbb{B}^1. I will describe why these should be rare and special, the previously-known examples (coming from triangle groups and Teichm\\'uller curves), and my recent construction of the first cocompact nonarithmetic Fuchsian groups with a modular embedding that are not commensurable with a triangle group.",
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        "location_name":"East Hall",
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        "tags":["Mathematics"],
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        "sponsors":[
             {
                "group_name":"Topology Seminar - Department of Mathematics",
                "group_id":"4910",
                "website":""                },             {
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        "datetime_modified":"20250912T113154",
        "datetime_start":"20251024T160000",
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        "has_end_time":1,
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        "date_end":"2025-10-24",
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        "time_zone":"America\/Detroit",
        "event_title":"NERS Colloquium: Nuclear Energy in the United States: Growth or Decline?",
        "occurrence_title":"",
        "combined_title":"NERS Colloquium: Nuclear Energy in the United States: Growth or Decline?: Speaker: Jacopo Buongiorno, Massachusetts Institute of Technology",
        "event_subtitle":"Speaker: Jacopo Buongiorno, Massachusetts Institute of Technology",
        "event_type":"Workshop \/ Seminar",
        "event_type_id":"21",
        "description":"The NERS Colloquia Series invites leading researchers, industry experts, and thought leaders from across the nuclear engineering and radiological sciences community to share their insights with students, faculty, and guests. Covering a wide range of topics\u2014from cutting-edge research and emerging technologies to policy, education, and professional development\u2014the weekly talks offer an opportunity to explore current issues and innovations shaping the future of the field.",
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                "guid":"136755-21879086@events.umich.edu",
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        "tags":["Engineering","Michigan Engineering","Nuclear","Nuclear Engineering and Radiological Sciences","Science","Sustainability"],
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        "datetime_modified":"20250923T144811",
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        "time_start":"16:00:00",
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        "event_title":"Professor Renee Jorgensen, the Max Mendel Shaye Professor of Public Philosophy, Politics, and Economics, Endowed Professorship Lecture",
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        "event_title":"Summer in South Asia Symposium",
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