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        "time_start":"16:00:00",
        "time_end":"17:00:00",
        "time_zone":"America\/Detroit",
        "event_title":"Basic Research Computing on  the Great Lakes Cluster Workshop",
        "occurrence_title":"",
        "combined_title":"Basic Research Computing on  the Great Lakes Cluster Workshop: Jiashu Han",
        "event_subtitle":"Jiashu Han",
        "event_type":"Workshop \/ Seminar",
        "event_type_id":"21",
        "description":"\u201cGreat Lakes is a campus-wide high performance computing cluster (HPC) that serves the broad\r\nneeds of researchers across the university. The Great Lakes HPC Cluster is available to all researchers\r\non all campuses for simulation, modeling, machine learning, data science, genomics, and more. It\r\nuses Slurm workload manager to schedule jobs on a linux based operating system.\u201d\r\n(Source:\r\nhttps:\/\/its.umich.edu\/advanced-research-computing\/high-performance-computing\/great-lakes)\r\nThis workshop will cover some basic computing topics using the U-M Great Lakes Cluster.",
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        "room":"B737",
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        "datetime_modified":"20240815T095933",
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        "time_zone":"America\/Detroit",
        "event_title":"DCMB \/ CCMB Weekly Seminar",
        "occurrence_title":"",
        "combined_title":"DCMB \/ CCMB Weekly Seminar: Jingyi Jessica Li, PhD, \"Permutation Enhances the Rigor of Single-Cell Data Analysis\u201d",
        "event_subtitle":"Jingyi Jessica Li, PhD, \"Permutation Enhances the Rigor of Single-Cell Data Analysis\u201d",
        "event_type":"Lecture \/ Discussion",
        "event_type_id":"13",
        "description":"Abstract:\r\nEnsuring the reliability and accuracy of single-cell data analysis is critical, particularly in visualizing complex biological structures and addressing data sparsity. This talk introduces two novel statistical methods\u2014scDEED and mcRigor\u2014that leverage permutation-based techniques to enhance the rigor of these analyses.\r\n\r\nscDEED ([Xia et al., 2024, Nature Communications](https:\/\/www.nature.com\/articles\/s41467-024-45891-y)) addresses the challenge of evaluating the reliability of two-dimensional (2D) embeddings produced by visualization methods like t-SNE and UMAP, which are commonly used to visualize cell clusters. These methods, however, can sometimes misrepresent data structure, leading to erroneous interpretations. scDEED calculates a reliability score for each cell embedding, comparing the consistency between a cell's neighbors in the 2D embedding space and its pre-embedding neighbors. Cells with low reliability scores are flagged as dubious, while those with high scores are deemed trustworthy. Additionally, scDEED provides guidance for optimizing t-SNE and UMAP hyperparameters by minimizing the number of dubious embeddings, significantly improving visualization reliability across multiple datasets.\r\n\r\nmcRigor focuses on enhancing metacell partitioning in single-cell RNA-seq and ATAC-seq data analysis, a common strategy to address data sparsity by aggregating similar single cells into metacells. Existing algorithms often fail to verify metacell homogeneity, risking bias and spurious findings. mcRigor introduces a feature-correlation-based statistic to measure heterogeneity within a metacell, identifying dubious metacells composed of heterogeneous single cells. By optimizing metacell partitioning algorithm hyperparameters, mcRigor enhances the reliability of downstream analyses. Moreover, mcRigor allows for benchmarking and selecting the most suitable partitioning algorithm for a dataset, ensuring more robust discoveries.\r\n\r\nscDEED and mcRigor demonstrate the power of permutation-based approaches in refining single-cell data analysis, providing researchers with tools to achieve more accurate and reproducible insights into complex cellular processes.",
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        "datetime_modified":"20241002T170035",
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        "event_title":"Former Governors John Kasich and Steve Bullock on Democracy and Civic Discourse",
        "occurrence_title":"",
        "combined_title":"Former Governors John Kasich and Steve Bullock on Democracy and Civic Discourse: A Conversation Across Differences",
        "event_subtitle":"A Conversation Across Differences",
        "event_type":"Lecture \/ Discussion",
        "event_type_id":"13",
        "description":"Two former governors, one Republican and one Democrat, considered moderates in their respective parties, discuss ways in which to have civil and civic discourse in an era of political divisiveness. \r\n\r\nSpeaker bios:\r\n\r\nJohn Kasich served as the 69th Governor of Ohio (2011-2019). He touts his accomplishments as \"leading the Ohio Comeback, restoring Ohio\u2019s fiscal stability, diversifying the state\u2019s economy with more than 500,000 new private-sector jobs, expanding health care coverage for low-income Ohioans, protecting vulnerable residents, and championing a number of reforms to protect the environment.\" Kasich ran for President during the 2016 GOP primary. He was the last candidate to leave the race and finished third in the total delegate count. His message focused on unifying Americans rather than dividing them, championing the great potential of our citizens to make positive impacts in their own communities, a strong national defense and the importance of our international alliances. He previously served in Congress (1982-2000), where he was Chairman of the House Budget Committee and also served for 18 years on the Armed Services Committee. \r\n\r\nSteve Bullock was elected Montana\u2019s 24th Governor, serving from 2013-2020. He worked with a Republican-majority legislature to improve access to health care, kick dark money out of state elections, make record investments in education, protect access to public lands, invest in infrastructure, and strengthen Montana\u2019s economy. Bullock brought diverse interests together to address challenging issues, from sage grouse and forest management to the Main Street Montana Project. By executive action, he led the nation in preserving net neutrality and combating dark money. Nationally, Bullock was elected Chair of the National Governors Association, Western Governors Association and Democratic Governors Association. Bullock served as Montana\u2019s attorney general from 2009-2013. As attorney general, Bullock defended Montana\u2019s hundred-year ban on corporate campaign spending, gaining national prominence for leading the challenge to the Supreme Court\u2019s Citizens United decision.",
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        "datetime_modified":"20241007T100231",
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        "time_zone":"America\/Detroit",
        "event_title":"Reconstruction Problems",
        "occurrence_title":"",
        "combined_title":"Reconstruction Problems: Katherine Williams Booth",
        "event_subtitle":"Katherine Williams Booth",
        "event_type":"Workshop \/ Seminar",
        "event_type_id":"21",
        "description":"How much structure can we recover with limited information about a map? These reconstruction problems can be both surprising in how much structure can be built up, but also very sensitive to slight variations. In this talk, I will discuss iterations of this type of problem from several different areas, including complex analysis, Riemannian geometry, algebraic geometry, and geometric group theory.",
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        "datetime_modified":"20241024T123151",
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        "event_title":"Stand out when applying: Best practices & tips",
        "occurrence_title":"",
        "combined_title":"Stand out when applying: Best practices & tips",
        "event_subtitle":"",
        "event_type":"Careers \/ Jobs",
        "event_type_id":"2",
        "description":"Are you a nursing student aspiring to make a lasting impression during the application process? Join us for an exclusive webinar, where the esteemed Placement Coordinators from Mayo Clinic, with their wealth of experience in sifting through thousands of resumes and conducting daily interviews, will reveal the secrets to setting yourself apart and securing your dream nursing position.In this invaluable session, youwill:1. Insider Insights: Gain unique insights into the world of resume evaluation and interview selection directly from Mayo Clinic Placement Coordinators. Understand what sets exceptional candidates apart and how you can align your skills and experiences with the expectations of top healthcare institutions.2. Crafting a Winning Resume: Learn the artof creating a standout nursing resume that captures attention and highlights your unique strengths. Discover the key elements that Mayo Clinic looks for when reviewing resumes and get practical tips to make your application stand out.3. Preparing for Success in Interviews: Unlock the secrets to acing nursing interviews with confidence. Mayo Clinic Placement Coordinators will share best practices, common pitfalls to avoid, and strategies for effectively showcasing your passion for nursing and commitmentto patient care.4. Navigating Online Applications: Understand thenuances of online application systems and discover how to optimize your digital presence. Learn how to use technology to your advantage and increase your chances of being noticed in the competitive healthcare job market.5. Mayo Clinic Culture Fit: Explore the unique culture at Mayo Clinic and understand what qualities and values they prioritize in their nursing team. Learn how to align your personal and professional attributes withthe Mayo Clinic ethos to demonstrate your suitability as a candidate.6. Interactive Q&amp;A Session: Get personalized advice by participating in an interactive Q&amp;A session with Mayo Clinic Placement Coordinators. This is your chance to have your specific questions answered and gain insights tailored to your nursing career aspirations.Don't miss this golden opportunity to gain a competitive edge in your nursing career journey. Register now for \"Stand Out When Applying\" and let Mayo Clinic's expert Placement Coordinators guide you toward success!",
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        "date_end":"2024-10-09",
        "time_start":"16:00:00",
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        "time_zone":"America\/Detroit",
        "event_title":"The Invented Library of an Invented Disciple: Reimagining the \u201cJohannine\u201d Literature",
        "occurrence_title":"",
        "combined_title":"The Invented Library of an Invented Disciple: Reimagining the \u201cJohannine\u201d Literature: Hugo M\u00e9ndez",
        "event_subtitle":"Hugo M\u00e9ndez",
        "event_type":"Lecture \/ Discussion",
        "event_type_id":"13",
        "description":"The Christian Bible contains four texts attributed to a disciple of Jesus named \u201cJohn\u201d: the Gospel of John and the letters of 1 John, 2 John, and 3 John. But what do we know about the origins of these texts? Who really wrote them?\r\n\r\nThis presentation argues that these works are a chain of pseudepigrapha\u2014falsely authored works\u2014written by multiple pens over several decades.\r\n\r\nThe author of the Gospel invented a disciple of Jesus to serve as the narrator of his text; the authors of the letters, in turn, co-opted this character, fleshing out so many afterlives for him. This presentation traces this arc, showing how a single act of disguised authorship inspired a new literary tradition and shaped twenty centuries of Christian culture.\r\n\r\nHugo M\u00e9ndez is an Associate Professor of Religious Studies at the University of North Carolina at Chapel Hill, where he teaches New Testament and early Christianity. He is the author of *The Cult of Stephen in Jerusalem: Inventing a Patron Martyr* (Oxford University Press, 2022) and co-author of *The New Testament: A Historical Introduction to the Early Christian Writings*, 8th ed. (Oxford, 2024).",
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        "event_title":"The Joseph and Sally Handleman Lecture Series presents Jessica Watson",
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        "combined_title":"The Joseph and Sally Handleman Lecture Series presents Jessica Watson: Jessica Watson",
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        "description":"Celebrating Milestones: A Voyage Around the World\r\n\r\nOn Wednesday, Oct. 9, please join Sharon F. Matusik, Edward J. Frey Dean of Business, for a conversation with Jessica Watson, the youngest person to sail solo, nonstop, and unassisted around the world. At age 16, Watson spent 210 days at sea navigating some of the world\u2019s most challenging stretches of ocean. Watson\u2019s journey around the world is a testament to resilience. Amid adversity, she recognized the value of appreciating small victories and acknowledging progress at every step. Her perseverance and grit demonstrate that we all have the power to live our dreams \u2014 no matter how small or big they are.\r\n\r\nWhile sailing around the world, Watson filmed a documentary about her experience, which was later narrated by Sir Richard Branson. Within three months of her return to Australia, she authored a book titled True Spirit, which told the story of her voyage. In February of 2024, a film adaptation of her book was released on Netflix and had over 30 million viewing hours in the first 10 days following its release. Now aged 30, Watson has completed an MBA, authored a second book, and currently works as a management consultant within Deloitte\u2019s Human Capital Practice.\r\n\r\n\r\nOct. 9, presentation 4-5 pm, reception to follow \r\nMichigan Ross Tauber Colloquium\r\nFree and open to the public -\u00a0RSVP Required",
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