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Words and phrases, emoticons and emojis, pronouns in bios, tattoos and piercings, skin color and eye shape, flags and insignia, diplomas and certificates, standardized test scores, and prices in markets \u2014 these are all carriers of information demanding attention and interpretation. We attach meanings to these messages, and they shape our actions in ways large and small. This lecture is motivated by the conviction that something useful can be said about economic and social life if one examines signals \u2014 despite their bewildering variety and complexity \u2014 from a unified perspective, with a focus on statistical inference and strategic incentives.\n\nRajiv Sethi is a Professor of Economics at Barnard College, Columbia University and an External Professor at the Santa Fe Institute. He is a 2025-26 fellow at the Center for Advanced Study in the Behavioral Sciences (CASBS) at Stanford University. 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