{ "146268-21898808": { "datetime_modified":"20260306T133125", "datetime_start":"20260320T150000", "datetime_end":"20260320T173000", "has_end_time":1, "date_start":"2026-03-20", "date_end":"2026-03-20", "time_start":"15:00:00", "time_end":"17:30:00", "time_zone":"America\/Detroit", "event_title":"Bike Repair Hours", "occurrence_title":"", "combined_title":"Bike Repair Hours", "event_subtitle":"", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Does your bike need a tune-up? Need help fixing a flat or getting your gears to shift smoothly? \nSign up for a 30-minute slot and your bike for peer-to-peer bike repair and maintenance. Our volunteers can help you diagnose bike problems, guide you through repairs, and provide the tools & materials needed to get you back to riding.\n\nEvery Wednesday from 4-6pm and Friday from 3-5:30pm in the Duderstadt Fabrication Underground (B430-Lower Level) SIGN UP HERE: https:\/\/tr.ee\/Lp9kLnnfP9\n \nThe Duderstadt Fabrication Underground's Bike Repair rack is available for use during all operation hours (M-F 12-6p). WoW Volunteers will only be there at our dedicated support hours with additional materials (tire patches, grease, etc). \n\nThis is NOT a drop-off service: ALL participants are expected to stay and participate in repairs to learn basic bike maintenance with the support of our volunteers. Expect to get your hands dirty and leave feeling more confident in your skills!\n\nIf you are interested in becoming a volunteer at any skill level for our new program, please email wolverinesonwheels-admin@umich.edu or sign up here: https:\/\/docs.google.com\/spreadsheets\/d\/1QVMuOatF-toPc_ky9QIAeeD0ob-ndBGA4uUFm9EAZ0g\/edit?usp=sharing", "occurrence_notes":"Wipe your tires THEN your bike down using the elevator. 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The aim of the bigger project is to present a big picture account that brings together the metaphysical, moral\/rational, and political aspects of free agency in relation to each other. The first part is about the metaphysics of the free will problem. The middle, the topic of this talk, is about rational or intentional agency. And the third part is about political freedom. The aim of the talk is to present an account of practical rational capacities that shows how the idea of acting under rational constraints gets us (part of) an account of free will, as well as to say a little about how I see this as relating to the metaphysics, especially the intuitive idea that, when the agent acts, the future is (at least in some ways) open. \n\n\n\nLucy Allais is a philosopher who holds academic positions at both the University of the Witwatersrand and Johns Hopkins University. 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Join us this Friday to celebrate :)", "occurrence_notes":null, "guid":"146727-21899557@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/146727", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"East Quad Basement", "has_livestream":0, "cost":"", "tags":[], "website":"https:\/\/maizepages.umich.edu\/event\/12344496", "sponsors":[ { "group_name":"Maize Pages Student Organizations", "group_id":"2390", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/03\/event_146727_original-11.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_thumb\/media\/attachments\/2026\/03\/event_146727_original-11.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/03\/event_146727_original-11.png", 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As transfer students, the Ambassadors understand the questions you have and designed a tour with the needs of transfer students in mind.\n\nPlease register using the link to the right.", "occurrence_notes":null, "guid":"95236-21895064@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/95236", "building_id":"1000150", "building_name":"LSA Building", "campus_maps_id":"87", "room":"1180 (Transfer Student Center)", "location_name":"LSA Building", "has_livestream":0, "cost":"", "tags":["transfer","Transfer Student Center","Transfer Students"], "website":"https:\/\/events.blackthorn.io\/en\/Hn1RKit7\/g\/1mzVXSHRqX", "sponsors":[ { "group_name":"LSA Transfer Student Center", "group_id":"4442", "website":"" }, { "group_name":"LSA Student Recruitment", "group_id":"4928", "website":"https:\/\/lsa.umich.edu\/lsa\/faculty-staff\/undergraduate-education\/student-recruitment.html" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2022\/05\/event_95236_original-1.jpeg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2022\/05\/event_95236_original-1.jpeg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2022\/05\/event_95236_original-1.jpeg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2022\/05\/event_95236_original-1.jpeg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2022\/05\/event_95236_original-1.jpeg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2022\/05\/event_95236_original-1.jpeg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2022\/05\/event_95236_original-1.jpeg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2022\/05\/event_95236_original-1.jpeg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2022\/05\/event_95236_original-1.jpeg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2022\/05\/event_95236_original-1.jpeg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2022\/05\/event_95236_original-1.jpeg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2022\/05\/event_95236_original-1.jpeg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2022\/05\/event_95236_original-1.jpeg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2022\/05\/event_95236_original-1.jpeg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2022\/05\/event_95236_original-1.jpeg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2022\/05\/event_95236_original-1.jpeg" }, "occurrence_count":5, "first_occurrence":21895061 } , "146579-21899308": { "datetime_modified":"20260313T144639", "datetime_start":"20260320T150000", "datetime_end":"20260320T163000", "has_end_time":1, "date_start":"2026-03-20", "date_end":"2026-03-20", "time_start":"15:00:00", "time_end":"16:30:00", "time_zone":"America\/Detroit", "event_title":"Many Voices, One Community: Oral Histories of Black Life at Michigan Law", "occurrence_title":"", "combined_title":"Many Voices, One Community: Oral Histories of Black Life at Michigan Law", "event_subtitle":"", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"Critical Oral Histories captures the evolving story of Michigan Law through the stories of its alumni. As part of the University\u2019s efforts to create a more inclusive history, this project strengthens intergenerational connections between professors, students, and alumni and celebrates the diverse experiences that have shaped the Michigan Law community. Join us for an interactive experience of Michigan Law\u2019s Oral History archives, highlighted by a panel of alumni participants whose stories form the heart of the project. They will offer reflections on their time at Michigan Law, the impact it\u2019s had on their careers, and guidance for today\u2019s students.", "occurrence_notes":null, "guid":"146579-21899308@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/146579", "building_id":"1000179", "building_name":"Hutchins Hall", "campus_maps_id":"72", "room":"Robert B. 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Through this lack of compartmentalization, the bacterial DNA or nucleoid, is free to act as a platform for both organization and coordination of complex bacterial structures and processes. A lack of a membrane boundary also increases the influence that the metabolic state of the cell can have on the DNA. The ParA family of ATPases is a well characterized family of positioning systems that is known to use the nucleoid as a matrix to organize chromosomes, plasmids, chemotaxis arrays, and bacterial microcompartments (BMCs). One of the best characterized BMCs is the carboxysome. Carboxysomes are proteinaceous structures that encapsulate the enzyme ribulose-1,5-bisphosphate carboxylase\/oxygenase (RuBisCO). Cyanobacteria and some chemoautotrophs use carboxysomes to enhance carbon fixation, maximizing the amount of carbon that can later be turned into biomass. Our group has worked to characterize the ParA-like positioning system, the maintenance of carboxysome distribution (Mcd) system, that organizes carboxysomes along the length of the cell. This is a two-component system, with the ParA-like ATPase, McdA, and its partner protein McdB, that interacts with carboxysomes. When McdA binds the nucleoid non-specifically in its ATP-bound state, McdB-coated carboxysomes stimulate the hydrolysis of ATP, causing McdA to dissociate from the nucleoid. This creates dynamic gradients of McdA, with McdB bound carboxysomes constantly chasing higher concentrations of McdA, thereby distributing carboxysomes along the nucleoid. \nWe have worked to characterize both McdA and McdB and their role in carboxysome positioning, however, until my thesis work, we did not consider the contribution of the nucleoid in the organization of carboxysomes. As a result, current models treat the nucleoid as a benign matrix for positioning by the McdAB system. Also, the McdAB system has been primarily studied in exponential cells grown under continuous light conditions. However, the natural environment of cyanobacteria fluctuates, with changing amounts of nutrient availability. Cells often change the compaction state of their DNA in response to environmental changes, so we used several environmental conditions, to induce changes in nucleoid architecture, to assess effects on the McdAB system and carboxysome organization. We found that the nucleoid is not a passive matrix and can contribute to carboxysome positioning during times of reduced McdAB localization. These findings likely apply to other cargoes that use the nucleoid as a positioning scaffold, and it is necessary to reassess how we understand subcellular organization in bacteria under this new paradigm. \nWhile we have investigated carboxysome organization and its McdAB positioning system, we have largely not considered other subcellular structures that could influence carboxysome distribution. Polyphosphate granules are a storage form of phosphate that is conserved across all domains of life and have been implicated in diverse cellular processes, including the regulation of bacterial chromatin. Through electron microscopy studies, carboxysomes and polyphosphate (polyP) granules have been shown to physically interact. The exact mechanism of this relationship and the significance of this association have not been investigated. We find that polyP influences both nucleoid compaction state and carboxysome positioning in the model cyanobacterium Synechococcus elongatus PCC 7942. Together, this work highlights the broader roles of both the nucleoid and other subcellular structures in the organization of the model BMC, the carboxysome.", "occurrence_notes":null, "guid":"146399-21899042@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/146399", "building_id":"1005169", "building_name":"Biological Sciences Building", "campus_maps_id":"631", "room":"1010", "location_name":"Biological Sciences Building", "has_livestream":0, "cost":"", "tags":["Biology","Bsbsigns","Dissertation Defense"], "website":"https:\/\/lsa.umich.edu\/mcdb\/news-events\/all-events.html#q=&filter=&start=&end=03\/10\/2027&tags=", "sponsors":[ { "group_name":"Department of Molecular, Cellular, and Developmental Biology", "group_id":"3755", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/03\/event_146399_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_thumb\/media\/attachments\/2026\/03\/event_146399_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/03\/event_146399_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2026\/03\/event_146399_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2026\/03\/event_146399_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb\/media\/attachments\/2026\/03\/event_146399_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_thumb_square\/media\/attachments\/2026\/03\/event_146399_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/group_large\/media\/attachments\/2026\/03\/event_146399_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2026\/03\/event_146399_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_large_crop\/media\/attachments\/2026\/03\/event_146399_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_list\/media\/attachments\/2026\/03\/event_146399_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2026\/03\/event_146399_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2026\/03\/event_146399_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_grid_2x\/media\/attachments\/2026\/03\/event_146399_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/resolve\/event_feature_large\/media\/attachments\/2026\/03\/event_146399_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2026\/03\/event_146399_original-1.png" }, "occurrence_count":1, "first_occurrence":21899042 } , "146723-21899555": { "datetime_modified":"20260317T184026", "datetime_start":"20260320T150000", "datetime_end":"20260320T180000", "has_end_time":1, "date_start":"2026-03-20", "date_end":"2026-03-20", "time_start":"15:00:00", "time_end":"18:00:00", "time_zone":"America\/Detroit", "event_title":"Residential College Aquarium Grand Opening!", "occurrence_title":"", "combined_title":"Residential College Aquarium Grand Opening!", "event_subtitle":"", "event_type":"Ceremony \/ Service", "event_type_id":"3", "description":"Michigan Fishkeeping is partnering with the Residential College and the University of Michigan Arts Initiative (through their student mini-grant program) to unveil an aquarium in East Quad! 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