{ "138328-21882777": { "datetime_modified":"20260227T104430", "datetime_start":"20260319T120000", "datetime_end":"20260319T130000", "has_end_time":1, "date_start":"2026-03-19", "date_end":"2026-03-19", "time_start":"12:00:00", "time_end":"13:00:00", "time_zone":"America\/Detroit", "event_title":"Introducing the Longitudinal Study of Health and Ageing in Kenya (LOSHAK)", "occurrence_title":"", "combined_title":"Introducing the Longitudinal Study of Health and Ageing in Kenya (LOSHAK): Josh Ehrlich, part of the ISR Insights Speaker Series", "event_subtitle":"Josh Ehrlich, part of the ISR Insights Speaker Series", "event_type":"Lecture \/ Discussion", "event_type_id":"13", "description":"Many countries in Sub-Saharan Africa are experiencing rapid demographic shifts, including an unprecedented aging of their populations. Kenya is at the front end of these transitions and is projected to experience a 4-fold increase in the number of adults over age 60 in just three decades. The Longitudinal Study of Health and Ageing in Kenya (LOSHAK) was developed to collect data on health and economic wellbeing among older Kenyans. LOSHAK is harmonized with other studies in the Health and Retirement Study (HRS) and Harmonized Cognitive Assessment Protocol (HCAP) families of studies. We anticipate that LOSHAK will serve as an important resource for policy, public health, and economic planners in Kenya and the region as they aim to address the varied social, health, and economic consequences of aging populations. This talk will focus on the development of LOSHAK and plans for its future.\n\nWatch a preview of this talk at https:\/\/youtu.be\/uGRcmnvYbBc", "occurrence_notes":null, "guid":"138328-21882777@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/138328", "building_id":"1000145", "building_name":"Institute For Social Research", "campus_maps_id":"76", "room":"1430", "location_name":"Institute For Social Research", "has_livestream":0, "cost":"", "tags":["Insights Speaker Series","Social Sciences","Public Health"], "website":"https:\/\/isr.umich.edu\/about\/faculty-profiles\/josh-ehrlich\/", "sponsors":[ { "group_name":"Institute for Social Research", "group_id":"3285", "website":"http:\/\/isr.umich.edu" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2025\/11\/event_138328_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2025\/11\/crop-event_138328_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2025\/11\/crop-event_138328_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2025\/11\/crop-event_138328_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2025\/11\/crop-event_138328_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2025\/11\/crop-event_138328_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2025\/11\/crop-event_138328_original-1.png", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2025\/11\/crop-event_138328_original-1.png", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2025\/11\/crop-event_138328_original-1.png", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2025\/11\/crop-event_138328_original-1.png", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2025\/11\/crop-event_138328_original-1.png", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2025\/11\/crop-event_138328_original-1.png", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2025\/11\/crop-event_138328_original-1.png", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2025\/11\/crop-event_138328_original-1.png", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2025\/11\/crop-event_138328_original-1.png", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2025\/11\/crop-event_138328_original-1.png" }, "occurrence_count":1, "first_occurrence":21882777 } , "145583-21897554": { "datetime_modified":"20260319T112048", "datetime_start":"20260319T120000", "datetime_end":"20260319T130000", "has_end_time":1, "date_start":"2026-03-19", "date_end":"2026-03-19", "time_start":"12:00:00", "time_end":"13:00:00", "time_zone":"America\/Detroit", "event_title":"IPE - Booking Flights on a Budget", "occurrence_title":"", "combined_title":"IPE - Booking Flights on a Budget", "event_subtitle":"", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Learn how to book your flight in the most savvy way! Save money by booking on the right sites at the right time and more.", "occurrence_notes":null, "guid":"145583-21897554@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/145583", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"", "has_livestream":0, "cost":"", "tags":["Sessions"], "website":"https:\/\/sessions.studentlife.umich.edu\/p\/track\/16597", "sponsors":[ { "group_name":"Sessions @ Michigan", "group_id":"4791", "website":"https:\/\/sessions.studentlife.umich.edu\/" } ], "image_url":"", "styled_images":{ "event_thumb":"", "event_large":"", "event_large_2x":"", "event_large_lightbox":"", "group_thumb":"", "group_thumb_square":"", "group_large":"", "group_large_lightbox":"", "event_large_crop":"", "event_list":"", "event_list_2x":"", "event_grid":"", "event_grid_2x":"", "event_feature_large":"", "event_feature_thumb":"" }, "occurrence_count":1, "first_occurrence":21897554 } , "145539-21897495": { "datetime_modified":"20260319T181514", "datetime_start":"20260319T120000", "datetime_end":"20260319T170000", "has_end_time":1, "date_start":"2026-03-19", "date_end":"2026-03-19", "time_start":"12:00:00", "time_end":"17:00:00", "time_zone":"America\/Detroit", "event_title":"Legacies: Contemporary Art Dialogues with Clay", "occurrence_title":"", "combined_title":"Legacies: Contemporary Art Dialogues with Clay", "event_subtitle":"", "event_type":"Exhibition", "event_type_id":"7", "description":"\n\nOn the occasion of the 2026 NCECA conference in Detroit, Stamps Gallery presents an exhibition of new and recent work by diverse intergenerational artists working in clay locally and nationally. Collectively, these works preserve and evolve age-old artistic traditions from weaving, mark-making, and pottery as contemporary forms of resistance and resilience; recovery and regeneration that draw on diasporic and ancestral knowledge of world-building and translation.\n\nFeaturing work by Maya Davis, Adebunmi Gbadebo, Nicole Marroquin, Marie Woo, and Hedy Yang. Curated by Srimoyee Mitra.\n\nDDD Project Space, 2857 East Grand Blvd Suite 104, Detroit MI\n\nExhibition Dates and Hours: March 13\u2009\u2013\u200928, 2026\n\nFri., March 13 and 20: 12\u20146 p.m.\nSat., March 14 and 21: 12\u20145 p.m.\nTue\u2014Wed, March 24\u201425: 11 a.m.\u20145 p.m.\nThu., March 26: 12\u20147 p.m.\nFri., March 27: 12\u20149 p.m.\nSat., March 28: 12\u20145 p.m.\n\nExhibition Reception: Fri., March 27, 5:30\u2009\u2014\u20099 p.m.", "occurrence_notes":null, "guid":"145539-21897495@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/145539", "building_id":"null", "building_name":"Off Campus Location", "campus_maps_id":"1", "room":"", "location_name":"DDD Project Space, 2857 E Grand Blvd, Detroit, MI 48202", "has_livestream":0, "cost":"", "tags":["Art"], "website":"https:\/\/stamps.umich.edu\/events\/legacies-contemporary-art-dialogues-with-clay", "sponsors":[ { "group_name":"Penny W Stamps School of Art & Design", "group_id":"3157", "website":"http:\/\/stamps.umich.edu\/" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/03\/event_145539_original-4.jpg", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2026\/03\/event_145539_original-4.jpg", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/03\/event_145539_original-4.jpg", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2026\/03\/event_145539_original-4.jpg", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2026\/03\/event_145539_original-4.jpg", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2026\/03\/event_145539_original-4.jpg", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2026\/03\/event_145539_original-4.jpg", "group_large":"https:\/\/events.umich.edu\/media\/cache\/group_large\/media\/attachments\/2026\/03\/event_145539_original-4.jpg", "group_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/group_large_lightbox\/media\/attachments\/2026\/03\/event_145539_original-4.jpg", "event_large_crop":"https:\/\/events.umich.edu\/media\/cache\/event_large_crop\/media\/attachments\/2026\/03\/event_145539_original-4.jpg", "event_list":"https:\/\/events.umich.edu\/media\/cache\/event_list\/media\/attachments\/2026\/03\/event_145539_original-4.jpg", "event_list_2x":"https:\/\/events.umich.edu\/media\/cache\/event_list_2x\/media\/attachments\/2026\/03\/event_145539_original-4.jpg", "event_grid":"https:\/\/events.umich.edu\/media\/cache\/event_grid\/media\/attachments\/2026\/03\/event_145539_original-4.jpg", "event_grid_2x":"https:\/\/events.umich.edu\/media\/cache\/event_grid_2x\/media\/attachments\/2026\/03\/event_145539_original-4.jpg", "event_feature_large":"https:\/\/events.umich.edu\/media\/cache\/event_feature_large\/media\/attachments\/2026\/03\/event_145539_original-4.jpg", "event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2026\/03\/event_145539_original-4.jpg" }, "occurrence_count":12, "first_occurrence":21897491 } , "146398-21899041": { "datetime_modified":"20260310T103518", "datetime_start":"20260319T120000", "datetime_end":"20260319T130000", "has_end_time":1, "date_start":"2026-03-19", "date_end":"2026-03-19", "time_start":"12:00:00", "time_end":"13:00:00", "time_zone":"America\/Detroit", "event_title":"MCDB Dissertation Defense Seminar> Bacterial Ribonuclease HII and Ribonucleotide Excision Repair", "occurrence_title":"", "combined_title":"MCDB Dissertation Defense Seminar> Bacterial Ribonuclease HII and Ribonucleotide Excision Repair: Julianna R. Cresti", "event_subtitle":"Julianna R. Cresti", "event_type":"Workshop \/ Seminar", "event_type_id":"21", "description":"Although RNA-DNA hybrids are essential to the perpetuation of life, if left unresolved, ribonucleoside monophosphates (rNMPs) embedded in the genome are a threat to faithful DNA replication, genomic integrity, and genetic inheritance. Single rNMPs, which differ from deoxyribonucleoside monophosphates (dNMPs) by a single 2\u2032 \u2013OH group, often become misincorporated in the genome by replicative DNA polymerases during DNA replication. Although DNA polymerases have a steric exclusion mechanism to prevent rNTPs from accessing their active site, rNTPs outnumber dNTPs in the cell and as a result are still frequently used as substrates during synthesis. rNMPs, also known as \u201csugar errors,\u201d that go unrepaired can lead to increased mutagenesis in the form of transitions, single-stranded breaks, and even lethal double-stranded breaks (DSBs) due to the reactivity of the 2\u2032 \u2013OH. However, cells have evolved to combat sugar errors through ribonucleotide excision repair (RER), which is initiated by Ribonuclease HII\/H2 (RNase HII). RNase HII is a Type 2 RNase H enzyme that makes a 5\u2032 incision to a rNMP in double-stranded DNA (dsDNA), permitting subsequent entry by a DNA polymerase. The polymerase extends from the 3\u2032 \u2013OH of the nick, displacing the downstream DNA containing the rNMP to generate a 5\u2032 flap, which can be resolved by a flap endonuclease (FEN). Finally, DNA ligase seals the gap in the backbone. The junction-sensing module of RNase HII is a critical structural element that gives the protein its unique ability to specifically recognize single rNMPs by their 2\u2032 \u2013OH. RER has been previously studied in eukaryotes, archaea, and bacteria, although the breadth of lesions addressed by bacterial RNase HII enzymes has not yet been established. We performed in vitro assays using RNase HII purified from Escherichia coli and Bacillus subtilis and dsDNA substrates containing single canonical, mismatched, and damaged rNMPs. Specifically, E. coli RNase HII (EcoRNase HII) was equally active on all four canonical rNMPs, including rUMP, while B. subtilis RNase HII (BsuRNase HII) was inefficient at processing rGMP. In a mismatched context, EcoRNase HII activity on rAMP and rGMP was unchanged from that on canonical rNMPs. Conversely, BsuRNase HII activity on rG:dT was significantly reduced from that on rG:dC. Further, EcoRNase HII demonstrated weak activity on r8oG:dC, while BsuRNase HII could not resolve r8oG:dC nor rOH:dC. This observation is similar to that reported for archaeal and eukaryotic RNase HII homologs. Together, our results show that bacterial RNase HII proteins have different substrate preferences. Surprisingly, both EcoRNase HII and BsuRNase HII are able to incise rUMP, suggesting that RER, and not base excision repair (BER), is the primary pathway for rUMP repair. Moreover, mismatched rNMP errors appear to be substrates for both RER and mismatch repair (MMR). Finally, damaged rNMP errors in B. subtilis must be repaired by an alternative pathway, potentially BER, although this has not yet been tested.", "occurrence_notes":null, "guid":"146398-21899041@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/146398", "building_id":"1005169", "building_name":"Biological Sciences Building", "campus_maps_id":"631", "room":"1010", "location_name":"Biological Sciences Building", "has_livestream":0, "cost":"", "tags":["Dissertation Defense","Bsbsigns","Biology"], "website":"https:\/\/lsa.umich.edu\/mcdb\/news-events\/all-events.html#q=&filter=&start=&end=03\/10\/2027&tags=", "sponsors":[ { "group_name":"Department of Molecular, Cellular, and Developmental Biology", "group_id":"3755", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/03\/event_146398_original-1.png", "styled_images":{ 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"event_feature_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_feature_thumb\/media\/attachments\/2026\/03\/event_146398_original-1.png" }, "occurrence_count":1, "first_occurrence":21899041 } , "143528-21893352": { "datetime_modified":"20260319T060050", "datetime_start":"20260319T120000", "datetime_end":"20260319T235959", "has_end_time":1, "date_start":"2026-03-19", "date_end":"2026-03-19", "time_start":"12:00:00", "time_end":"23:59:59", "time_zone":"America\/Detroit", "event_title":"Northwest Challenge 2026", "occurrence_title":"", "combined_title":"Northwest Challenge 2026", "event_subtitle":"", "event_type":"Other", "event_type_id":"22", "description":"tourney in seattle, wa!", "occurrence_notes":null, "guid":"143528-21893352@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/143528", "building_id":"", "building_name":"", "campus_maps_id":"", "room":"", "location_name":"University of Washington", "has_livestream":0, "cost":"", "tags":[], 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"event_type":"Exhibition", "event_type_id":"7", "description":"Thomas Paine\u2019s \u201cCommon Sense\u201d was one of the most influential works of the American Revolution. The first edition was published on January 10, 1776, with an initial print run of just 1,000 copies; but within weeks demand soared. The students of Andy Murphy\u2019s POLISCI 495 course co-curated the exhibition \u201cRevolutionary Paine\u201d to document the whirlwind caused by its publication. On view at the Clements January 16-May 8, weekdays from 12-4 pm.", "occurrence_notes":null, "guid":"143999-21894454@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/143999", "building_id":"1000159", "building_name":"William Clements Library", "campus_maps_id":"165", "room":"Avenir Foundation Reading Room", "location_name":"William Clements Library", "has_livestream":0, "cost":"", "tags":["Americana","history","Exhibition","Exhibit"], "website":"https:\/\/clements.umich.edu\/exhibit\/revolutionary-paine\/", "sponsors":[ { "group_name":"William L. Clements Library", "group_id":"1727", "website":"" } ], "image_url":"https:\/\/events.umich.edu\/media\/attachments\/2026\/01\/event_143999_original-1.png", "styled_images":{ "event_thumb":"https:\/\/events.umich.edu\/media\/cache\/event_thumb\/media\/attachments\/2026\/01\/event_143999_original-1.png", "event_large":"https:\/\/events.umich.edu\/media\/cache\/event_large\/media\/attachments\/2026\/01\/event_143999_original-1.png", "event_large_2x":"https:\/\/events.umich.edu\/media\/cache\/event_large_2x\/media\/attachments\/2026\/01\/event_143999_original-1.png", "event_large_lightbox":"https:\/\/events.umich.edu\/media\/cache\/event_large_lightbox\/media\/attachments\/2026\/01\/event_143999_original-1.png", "group_thumb":"https:\/\/events.umich.edu\/media\/cache\/group_thumb\/media\/attachments\/2026\/01\/event_143999_original-1.png", "group_thumb_square":"https:\/\/events.umich.edu\/media\/cache\/group_thumb_square\/media\/attachments\/2026\/01\/event_143999_original-1.png", 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U\u2011M, and treat your taste buds to chocolate delights from Central and Eastern Europe.\n\nExpand Your Palate\nExperience the diverse flavors of Slavic chocolate and broaden your culinary horizons.\n\nExplore Academic Opportunities\nDiscover the enriching programs and resources available through the Slavic Department.\n\nConnect with Peers\nMeet fellow students who share your interest in Slavic culture and chocolate indulgence.\n\nAll students from any U\u2011M school, college, or unit are welcome to join us in the 1st-floor MLB lobby.", "occurrence_notes":null, "guid":"146348-21898939@events.umich.edu", "permalink":"http:\/\/events.umich.edu\/event\/146348", "building_id":"1000207", "building_name":"Modern Languages Building", "campus_maps_id":"111", "room":"1st-Floor Lobby", "location_name":"Modern Languages Building", "has_livestream":0, "cost":"", "tags":["European","Language Resource Center","Info Session","Free","Food","Culture","Crees"], "website":"", "sponsors":[ { 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The largest bell, which strikes the hour, weighs 12 tons, while the smallest bell, 4\u00bd octaves above, weighs just 15 pounds.\n\nThirty-minute recitals are performed on the Charles Baird Carillon at noon every weekday that classes are in session, followed by visitor Q&A with the carillonist. The bell chamber may be accessed via a combination of elevator and stairs. Take the elevator to the highest floor possible (floor 8), and then climb two flights of stairs (39 steps) to the bell chamber (floor 10). Hearing protection earmuffs are provided for visitors. Be prepared to walk on ice and snow in the bell chamber during winter. Built in 1936, the Charles Baird Carillon is not ADA accessible. 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